Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage
![](/themes/Miragereponivs//images/openAccess.png)
2019
Authors
Hendriksen, Rene S.![](/themes/Miragereponivs/images/orcid.png)
Munk, Patrick
![](/themes/Miragereponivs/images/orcid.png)
Njage, Patrick
![](/themes/Miragereponivs/images/orcid.png)
van Bunnik, Bram
![](/themes/Miragereponivs/images/orcid.png)
McNally, Luke
Lukjancenko, Oksana
Roder, Timo
![](/themes/Miragereponivs/images/orcid.png)
Nieuwenhuijse, David
Pedersen, Susanne Karlsmose
![](/themes/Miragereponivs/images/orcid.png)
Kjeldgaard, Jette
![](/themes/Miragereponivs/images/orcid.png)
Kaas, Rolf S.
![](/themes/Miragereponivs/images/orcid.png)
Clausen, Philip
![](/themes/Miragereponivs/images/orcid.png)
Vogt, Josef Korbinian
![](/themes/Miragereponivs/images/orcid.png)
Leekitcharoenphon, Pimlapas
![](/themes/Miragereponivs/images/orcid.png)
van de Schans, Milou G. M.
![](/themes/Miragereponivs/images/orcid.png)
Zuidema, Tina
Husman, Ana Maria de Roda
Rasmussen, Simon
Petersen, Bent
![](/themes/Miragereponivs/images/orcid.png)
Amid, Clara
![](/themes/Miragereponivs/images/orcid.png)
Cochrane, Guy
![](/themes/Miragereponivs/images/orcid.png)
Sicheritz-Ponten, Thomas
Schmitt, Heike
![](/themes/Miragereponivs/images/orcid.png)
Alvarez, Jorge Raul Matheu
Aidara-Kane, Awa
Pamp, Sunje J.
![](/themes/Miragereponivs/images/orcid.png)
Lund, Ole
![](/themes/Miragereponivs/images/orcid.png)
Hald, Tine
![](/themes/Miragereponivs/images/orcid.png)
Woolhouse, Mark
Koopmans, Marion P.
![](/themes/Miragereponivs/images/orcid.png)
Vigre, Hakan
Petersen, Thomas Nordahl
![](/themes/Miragereponivs/images/orcid.png)
Aarestrup, Frank M.
![](/themes/Miragereponivs/images/orcid.png)
Bego, Artan
Rees, Catherine
Cassar, Susan
Coventry, Kris
Collignon, Peter
Allerberger, Franz
Rahube, Teddie O.
![](/themes/Miragereponivs/images/orcid.png)
Oliveira, Guilherme
Ivanov, Ivan
Vuthy, Yith
Sopheak, Thet
Yost, Christopher K.
![](/themes/Miragereponivs/images/orcid.png)
Ke, Changwen
Zheng, Huanying
Li, Baisheng
Jiao, Xiaoyang
Donado-Godoy, Pilar
Coulibaly, Kalpy Julien
Jergović, Matijana
Hrenović, Jasna
![](/themes/Miragereponivs/images/orcid.png)
Karpiskova, Renata
![](/themes/Miragereponivs/images/orcid.png)
Eduardo Villacis, Jose
![](/themes/Miragereponivs/images/orcid.png)
Legesse, Mengistu
Eguale, Tadesse
![](/themes/Miragereponivs/images/orcid.png)
Heikinheimo, Annamari
![](/themes/Miragereponivs/images/orcid.png)
Malania, Lile
Nitsche, Andreas
![](/themes/Miragereponivs/images/orcid.png)
Brinkmann, Annika
Saba, Courage Kosi Setsoafia
Kocsis, Bela
![](/themes/Miragereponivs/images/orcid.png)
Solymosi, Norbert
Thorsteinsdottir, Thorunn R.
Hatha, Abdulla Mohamed
![](/themes/Miragereponivs/images/orcid.png)
Alebouyeh, Masoud
Morris, Dearbhaile
![](/themes/Miragereponivs/images/orcid.png)
Cormican, Martin
![](/themes/Miragereponivs/images/orcid.png)
O'Connor, Louise
Moran-Gilad, Jacob
![](/themes/Miragereponivs/images/orcid.png)
Alba, Patricia
![](/themes/Miragereponivs/images/orcid.png)
Battisti, Antonio
![](/themes/Miragereponivs/images/orcid.png)
Shakenova, Zeinegul
Kiiyukia, Ciira
Ng'eno, Eric
Raka, Lul
Avsejenko, Jelena
Berzins, Aivars
![](/themes/Miragereponivs/images/orcid.png)
Bartkevics, Vadims
![](/themes/Miragereponivs/images/orcid.png)
Penny, Christian
Rajandas, Heraa
![](/themes/Miragereponivs/images/orcid.png)
Parimannan, Sivachandran
![](/themes/Miragereponivs/images/orcid.png)
Haber, Malcolm Vella
Pal, Pushkar
![](/themes/Miragereponivs/images/orcid.png)
Jeunen, Gert-Jan
Gemmell, Neil
Fashae, Kayode
Holmstad, Rune
Hasan, Rumina
Shakoor, Sadia
Rojas, Maria Luz Zamudio
Wasyl, Dariusz
![](/themes/Miragereponivs/images/orcid.png)
Bosevska, Golubinka
Kochubovski, Mihail
Radu, Cojocaru
Gassama, Amy
Radosavljević, Vladimir
![](/themes/Miragereponivs/images/orcid.png)
Wuertz, Stefan
Zuniga-Montanez, Rogelio
![](/themes/Miragereponivs/images/orcid.png)
Tay, Moon Y. F.
Gavacova, Dagmar
Pastuchova, Katarina
Truska, Peter
Trkov, Marija
![](/themes/Miragereponivs/images/orcid.png)
Esterhuyse, Kerneels
Keddy, Karen
![](/themes/Miragereponivs/images/orcid.png)
Cerda-Cuellar, Marta
![](/themes/Miragereponivs/images/orcid.png)
Pathirage, Sujatha
Norrgren, Leif
Orn, Stefan
Larsson, D. G. Joakim
![](/themes/Miragereponivs/images/orcid.png)
Van der Heijden, Tanja
Kumburu, Happiness Houka
Sanneh, Bakary
Bidjada, Pawou
Njanpop-Lafourcade, Berthe-Marie
Nikiema-Pessinaba, Somtinda Christelle
Levent, Belkis
Meschke, John Scott
Beck, Nicola Koren
Chinh, Dang Van
Nguyen, Do Phuc
Doan Minh Nguyen, Tran
Kwenda, Geoffrey
Tabo, Djim-Adjim
Wester, Astrid Louise
Cuadros-Orellana, Sara
![](/themes/Miragereponivs/images/orcid.png)
Article (Published version)
Metadata
Show full item recordAbstract
Antimicrobial resistance (AMR) is a serious threat to global public health, but obtaining representative data on AMR for healthy human populations is difficult. Here, we use meta-genomic analysis of untreated sewage to characterize the bacterial resistome from 79 sites in 60 countries. We find systematic differences in abundance and diversity of AMR genes between Europe/North-America/Oceania and Africa/Asia/South-America. Antimicrobial use data and bacterial taxonomy only explains a minor part of the AMR variation that we observe. We find no evidence for cross-selection between antimicrobial classes, or for effect of air travel between sites. However, AMR gene abundance strongly correlates with socio-economic, health and environmental factors, which we use to predict AMR gene abundances in all countries in the world. Our findings suggest that global AMR gene diversity and abundance vary by region, and that improving sanitation and health could potentially limit the global burden of AMR.... We propose metagenomic analysis of sewage as an ethically acceptable and economically feasible approach for continuous global surveillance and prediction of AMR.
Source:
Nature Communications, 2019, 10Publisher:
- Nature Portfolio, Berlin
Funding / projects:
- 643476
- World Health Organization
- Villum Foundation [VKR023052]
- Novo Nordisk Foundation [NNF16OC0021856]
DOI: 10.1038/s41467-019-08853-3
ISSN: 2041-1723
PubMed: 30850636
WoS: 000460631100009
Scopus: 2-s2.0-85062620273
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Institution/Community
Naučni institut za veterinarstvo SrbijeTY - JOUR AU - Hendriksen, Rene S. AU - Munk, Patrick AU - Njage, Patrick AU - van Bunnik, Bram AU - McNally, Luke AU - Lukjancenko, Oksana AU - Roder, Timo AU - Nieuwenhuijse, David AU - Pedersen, Susanne Karlsmose AU - Kjeldgaard, Jette AU - Kaas, Rolf S. AU - Clausen, Philip AU - Vogt, Josef Korbinian AU - Leekitcharoenphon, Pimlapas AU - van de Schans, Milou G. M. AU - Zuidema, Tina AU - Husman, Ana Maria de Roda AU - Rasmussen, Simon AU - Petersen, Bent AU - Amid, Clara AU - Cochrane, Guy AU - Sicheritz-Ponten, Thomas AU - Schmitt, Heike AU - Alvarez, Jorge Raul Matheu AU - Aidara-Kane, Awa AU - Pamp, Sunje J. AU - Lund, Ole AU - Hald, Tine AU - Woolhouse, Mark AU - Koopmans, Marion P. AU - Vigre, Hakan AU - Petersen, Thomas Nordahl AU - Aarestrup, Frank M. AU - Bego, Artan AU - Rees, Catherine AU - Cassar, Susan AU - Coventry, Kris AU - Collignon, Peter AU - Allerberger, Franz AU - Rahube, Teddie O. AU - Oliveira, Guilherme AU - Ivanov, Ivan AU - Vuthy, Yith AU - Sopheak, Thet AU - Yost, Christopher K. AU - Ke, Changwen AU - Zheng, Huanying AU - Li, Baisheng AU - Jiao, Xiaoyang AU - Donado-Godoy, Pilar AU - Coulibaly, Kalpy Julien AU - Jergović, Matijana AU - Hrenović, Jasna AU - Karpiskova, Renata AU - Eduardo Villacis, Jose AU - Legesse, Mengistu AU - Eguale, Tadesse AU - Heikinheimo, Annamari AU - Malania, Lile AU - Nitsche, Andreas AU - Brinkmann, Annika AU - Saba, Courage Kosi Setsoafia AU - Kocsis, Bela AU - Solymosi, Norbert AU - Thorsteinsdottir, Thorunn R. AU - Hatha, Abdulla Mohamed AU - Alebouyeh, Masoud AU - Morris, Dearbhaile AU - Cormican, Martin AU - O'Connor, Louise AU - Moran-Gilad, Jacob AU - Alba, Patricia AU - Battisti, Antonio AU - Shakenova, Zeinegul AU - Kiiyukia, Ciira AU - Ng'eno, Eric AU - Raka, Lul AU - Avsejenko, Jelena AU - Berzins, Aivars AU - Bartkevics, Vadims AU - Penny, Christian AU - Rajandas, Heraa AU - Parimannan, Sivachandran AU - Haber, Malcolm Vella AU - Pal, Pushkar AU - Jeunen, Gert-Jan AU - Gemmell, Neil AU - Fashae, Kayode AU - Holmstad, Rune AU - Hasan, Rumina AU - Shakoor, Sadia AU - Rojas, Maria Luz Zamudio AU - Wasyl, Dariusz AU - Bosevska, Golubinka AU - Kochubovski, Mihail AU - Radu, Cojocaru AU - Gassama, Amy AU - Radosavljević, Vladimir AU - Wuertz, Stefan AU - Zuniga-Montanez, Rogelio AU - Tay, Moon Y. F. AU - Gavacova, Dagmar AU - Pastuchova, Katarina AU - Truska, Peter AU - Trkov, Marija AU - Esterhuyse, Kerneels AU - Keddy, Karen AU - Cerda-Cuellar, Marta AU - Pathirage, Sujatha AU - Norrgren, Leif AU - Orn, Stefan AU - Larsson, D. G. Joakim AU - Van der Heijden, Tanja AU - Kumburu, Happiness Houka AU - Sanneh, Bakary AU - Bidjada, Pawou AU - Njanpop-Lafourcade, Berthe-Marie AU - Nikiema-Pessinaba, Somtinda Christelle AU - Levent, Belkis AU - Meschke, John Scott AU - Beck, Nicola Koren AU - Chinh, Dang Van AU - Nguyen, Do Phuc AU - Doan Minh Nguyen, Tran AU - Kwenda, Geoffrey AU - Tabo, Djim-Adjim AU - Wester, Astrid Louise AU - Cuadros-Orellana, Sara PY - 2019 UR - https://reponivs.nivs.rs/handle/123456789/389 AB - Antimicrobial resistance (AMR) is a serious threat to global public health, but obtaining representative data on AMR for healthy human populations is difficult. Here, we use meta-genomic analysis of untreated sewage to characterize the bacterial resistome from 79 sites in 60 countries. We find systematic differences in abundance and diversity of AMR genes between Europe/North-America/Oceania and Africa/Asia/South-America. Antimicrobial use data and bacterial taxonomy only explains a minor part of the AMR variation that we observe. We find no evidence for cross-selection between antimicrobial classes, or for effect of air travel between sites. However, AMR gene abundance strongly correlates with socio-economic, health and environmental factors, which we use to predict AMR gene abundances in all countries in the world. Our findings suggest that global AMR gene diversity and abundance vary by region, and that improving sanitation and health could potentially limit the global burden of AMR. We propose metagenomic analysis of sewage as an ethically acceptable and economically feasible approach for continuous global surveillance and prediction of AMR. PB - Nature Portfolio, Berlin T2 - Nature Communications T1 - Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage VL - 10 DO - 10.1038/s41467-019-08853-3 UR - conv_363 ER -
@article{ author = "Hendriksen, Rene S. and Munk, Patrick and Njage, Patrick and van Bunnik, Bram and McNally, Luke and Lukjancenko, Oksana and Roder, Timo and Nieuwenhuijse, David and Pedersen, Susanne Karlsmose and Kjeldgaard, Jette and Kaas, Rolf S. and Clausen, Philip and Vogt, Josef Korbinian and Leekitcharoenphon, Pimlapas and van de Schans, Milou G. M. and Zuidema, Tina and Husman, Ana Maria de Roda and Rasmussen, Simon and Petersen, Bent and Amid, Clara and Cochrane, Guy and Sicheritz-Ponten, Thomas and Schmitt, Heike and Alvarez, Jorge Raul Matheu and Aidara-Kane, Awa and Pamp, Sunje J. and Lund, Ole and Hald, Tine and Woolhouse, Mark and Koopmans, Marion P. and Vigre, Hakan and Petersen, Thomas Nordahl and Aarestrup, Frank M. and Bego, Artan and Rees, Catherine and Cassar, Susan and Coventry, Kris and Collignon, Peter and Allerberger, Franz and Rahube, Teddie O. and Oliveira, Guilherme and Ivanov, Ivan and Vuthy, Yith and Sopheak, Thet and Yost, Christopher K. and Ke, Changwen and Zheng, Huanying and Li, Baisheng and Jiao, Xiaoyang and Donado-Godoy, Pilar and Coulibaly, Kalpy Julien and Jergović, Matijana and Hrenović, Jasna and Karpiskova, Renata and Eduardo Villacis, Jose and Legesse, Mengistu and Eguale, Tadesse and Heikinheimo, Annamari and Malania, Lile and Nitsche, Andreas and Brinkmann, Annika and Saba, Courage Kosi Setsoafia and Kocsis, Bela and Solymosi, Norbert and Thorsteinsdottir, Thorunn R. and Hatha, Abdulla Mohamed and Alebouyeh, Masoud and Morris, Dearbhaile and Cormican, Martin and O'Connor, Louise and Moran-Gilad, Jacob and Alba, Patricia and Battisti, Antonio and Shakenova, Zeinegul and Kiiyukia, Ciira and Ng'eno, Eric and Raka, Lul and Avsejenko, Jelena and Berzins, Aivars and Bartkevics, Vadims and Penny, Christian and Rajandas, Heraa and Parimannan, Sivachandran and Haber, Malcolm Vella and Pal, Pushkar and Jeunen, Gert-Jan and Gemmell, Neil and Fashae, Kayode and Holmstad, Rune and Hasan, Rumina and Shakoor, Sadia and Rojas, Maria Luz Zamudio and Wasyl, Dariusz and Bosevska, Golubinka and Kochubovski, Mihail and Radu, Cojocaru and Gassama, Amy and Radosavljević, Vladimir and Wuertz, Stefan and Zuniga-Montanez, Rogelio and Tay, Moon Y. F. and Gavacova, Dagmar and Pastuchova, Katarina and Truska, Peter and Trkov, Marija and Esterhuyse, Kerneels and Keddy, Karen and Cerda-Cuellar, Marta and Pathirage, Sujatha and Norrgren, Leif and Orn, Stefan and Larsson, D. G. Joakim and Van der Heijden, Tanja and Kumburu, Happiness Houka and Sanneh, Bakary and Bidjada, Pawou and Njanpop-Lafourcade, Berthe-Marie and Nikiema-Pessinaba, Somtinda Christelle and Levent, Belkis and Meschke, John Scott and Beck, Nicola Koren and Chinh, Dang Van and Nguyen, Do Phuc and Doan Minh Nguyen, Tran and Kwenda, Geoffrey and Tabo, Djim-Adjim and Wester, Astrid Louise and Cuadros-Orellana, Sara", year = "2019", abstract = "Antimicrobial resistance (AMR) is a serious threat to global public health, but obtaining representative data on AMR for healthy human populations is difficult. Here, we use meta-genomic analysis of untreated sewage to characterize the bacterial resistome from 79 sites in 60 countries. We find systematic differences in abundance and diversity of AMR genes between Europe/North-America/Oceania and Africa/Asia/South-America. Antimicrobial use data and bacterial taxonomy only explains a minor part of the AMR variation that we observe. We find no evidence for cross-selection between antimicrobial classes, or for effect of air travel between sites. However, AMR gene abundance strongly correlates with socio-economic, health and environmental factors, which we use to predict AMR gene abundances in all countries in the world. Our findings suggest that global AMR gene diversity and abundance vary by region, and that improving sanitation and health could potentially limit the global burden of AMR. We propose metagenomic analysis of sewage as an ethically acceptable and economically feasible approach for continuous global surveillance and prediction of AMR.", publisher = "Nature Portfolio, Berlin", journal = "Nature Communications", title = "Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage", volume = "10", doi = "10.1038/s41467-019-08853-3", url = "conv_363" }
Hendriksen, R. S., Munk, P., Njage, P., van Bunnik, B., McNally, L., Lukjancenko, O., Roder, T., Nieuwenhuijse, D., Pedersen, S. K., Kjeldgaard, J., Kaas, R. S., Clausen, P., Vogt, J. K., Leekitcharoenphon, P., van de Schans, M. G. M., Zuidema, T., Husman, A. M. d. R., Rasmussen, S., Petersen, B., Amid, C., Cochrane, G., Sicheritz-Ponten, T., Schmitt, H., Alvarez, J. R. M., Aidara-Kane, A., Pamp, S. J., Lund, O., Hald, T., Woolhouse, M., Koopmans, M. P., Vigre, H., Petersen, T. N., Aarestrup, F. M., Bego, A., Rees, C., Cassar, S., Coventry, K., Collignon, P., Allerberger, F., Rahube, T. O., Oliveira, G., Ivanov, I., Vuthy, Y., Sopheak, T., Yost, C. K., Ke, C., Zheng, H., Li, B., Jiao, X., Donado-Godoy, P., Coulibaly, K. J., Jergović, M., Hrenović, J., Karpiskova, R., Eduardo Villacis, J., Legesse, M., Eguale, T., Heikinheimo, A., Malania, L., Nitsche, A., Brinkmann, A., Saba, C. K. S., Kocsis, B., Solymosi, N., Thorsteinsdottir, T. R., Hatha, A. M., Alebouyeh, M., Morris, D., Cormican, M., O'Connor, L., Moran-Gilad, J., Alba, P., Battisti, A., Shakenova, Z., Kiiyukia, C., Ng'eno, E., Raka, L., Avsejenko, J., Berzins, A., Bartkevics, V., Penny, C., Rajandas, H., Parimannan, S., Haber, M. V., Pal, P., Jeunen, G., Gemmell, N., Fashae, K., Holmstad, R., Hasan, R., Shakoor, S., Rojas, M. L. Z., Wasyl, D., Bosevska, G., Kochubovski, M., Radu, C., Gassama, A., Radosavljević, V., Wuertz, S., Zuniga-Montanez, R., Tay, M. Y. F., Gavacova, D., Pastuchova, K., Truska, P., Trkov, M., Esterhuyse, K., Keddy, K., Cerda-Cuellar, M., Pathirage, S., Norrgren, L., Orn, S., Larsson, D. G. J., Van der Heijden, T., Kumburu, H. H., Sanneh, B., Bidjada, P., Njanpop-Lafourcade, B., Nikiema-Pessinaba, S. C., Levent, B., Meschke, J. S., Beck, N. K., Chinh, D. V., Nguyen, D. P., Doan Minh Nguyen, T., Kwenda, G., Tabo, D., Wester, A. L.,& Cuadros-Orellana, S.. (2019). Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage. in Nature Communications Nature Portfolio, Berlin., 10. https://doi.org/10.1038/s41467-019-08853-3 conv_363
Hendriksen RS, Munk P, Njage P, van Bunnik B, McNally L, Lukjancenko O, Roder T, Nieuwenhuijse D, Pedersen SK, Kjeldgaard J, Kaas RS, Clausen P, Vogt JK, Leekitcharoenphon P, van de Schans MGM, Zuidema T, Husman AMDR, Rasmussen S, Petersen B, Amid C, Cochrane G, Sicheritz-Ponten T, Schmitt H, Alvarez JRM, Aidara-Kane A, Pamp SJ, Lund O, Hald T, Woolhouse M, Koopmans MP, Vigre H, Petersen TN, Aarestrup FM, Bego A, Rees C, Cassar S, Coventry K, Collignon P, Allerberger F, Rahube TO, Oliveira G, Ivanov I, Vuthy Y, Sopheak T, Yost CK, Ke C, Zheng H, Li B, Jiao X, Donado-Godoy P, Coulibaly KJ, Jergović M, Hrenović J, Karpiskova R, Eduardo Villacis J, Legesse M, Eguale T, Heikinheimo A, Malania L, Nitsche A, Brinkmann A, Saba CKS, Kocsis B, Solymosi N, Thorsteinsdottir TR, Hatha AM, Alebouyeh M, Morris D, Cormican M, O'Connor L, Moran-Gilad J, Alba P, Battisti A, Shakenova Z, Kiiyukia C, Ng'eno E, Raka L, Avsejenko J, Berzins A, Bartkevics V, Penny C, Rajandas H, Parimannan S, Haber MV, Pal P, Jeunen G, Gemmell N, Fashae K, Holmstad R, Hasan R, Shakoor S, Rojas MLZ, Wasyl D, Bosevska G, Kochubovski M, Radu C, Gassama A, Radosavljević V, Wuertz S, Zuniga-Montanez R, Tay MYF, Gavacova D, Pastuchova K, Truska P, Trkov M, Esterhuyse K, Keddy K, Cerda-Cuellar M, Pathirage S, Norrgren L, Orn S, Larsson DGJ, Van der Heijden T, Kumburu HH, Sanneh B, Bidjada P, Njanpop-Lafourcade B, Nikiema-Pessinaba SC, Levent B, Meschke JS, Beck NK, Chinh DV, Nguyen DP, Doan Minh Nguyen T, Kwenda G, Tabo D, Wester AL, Cuadros-Orellana S. Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage. in Nature Communications. 2019;10. doi:10.1038/s41467-019-08853-3 conv_363 .
Hendriksen, Rene S., Munk, Patrick, Njage, Patrick, van Bunnik, Bram, McNally, Luke, Lukjancenko, Oksana, Roder, Timo, Nieuwenhuijse, David, Pedersen, Susanne Karlsmose, Kjeldgaard, Jette, Kaas, Rolf S., Clausen, Philip, Vogt, Josef Korbinian, Leekitcharoenphon, Pimlapas, van de Schans, Milou G. M., Zuidema, Tina, Husman, Ana Maria de Roda, Rasmussen, Simon, Petersen, Bent, Amid, Clara, Cochrane, Guy, Sicheritz-Ponten, Thomas, Schmitt, Heike, Alvarez, Jorge Raul Matheu, Aidara-Kane, Awa, Pamp, Sunje J., Lund, Ole, Hald, Tine, Woolhouse, Mark, Koopmans, Marion P., Vigre, Hakan, Petersen, Thomas Nordahl, Aarestrup, Frank M., Bego, Artan, Rees, Catherine, Cassar, Susan, Coventry, Kris, Collignon, Peter, Allerberger, Franz, Rahube, Teddie O., Oliveira, Guilherme, Ivanov, Ivan, Vuthy, Yith, Sopheak, Thet, Yost, Christopher K., Ke, Changwen, Zheng, Huanying, Li, Baisheng, Jiao, Xiaoyang, Donado-Godoy, Pilar, Coulibaly, Kalpy Julien, Jergović, Matijana, Hrenović, Jasna, Karpiskova, Renata, Eduardo Villacis, Jose, Legesse, Mengistu, Eguale, Tadesse, Heikinheimo, Annamari, Malania, Lile, Nitsche, Andreas, Brinkmann, Annika, Saba, Courage Kosi Setsoafia, Kocsis, Bela, Solymosi, Norbert, Thorsteinsdottir, Thorunn R., Hatha, Abdulla Mohamed, Alebouyeh, Masoud, Morris, Dearbhaile, Cormican, Martin, O'Connor, Louise, Moran-Gilad, Jacob, Alba, Patricia, Battisti, Antonio, Shakenova, Zeinegul, Kiiyukia, Ciira, Ng'eno, Eric, Raka, Lul, Avsejenko, Jelena, Berzins, Aivars, Bartkevics, Vadims, Penny, Christian, Rajandas, Heraa, Parimannan, Sivachandran, Haber, Malcolm Vella, Pal, Pushkar, Jeunen, Gert-Jan, Gemmell, Neil, Fashae, Kayode, Holmstad, Rune, Hasan, Rumina, Shakoor, Sadia, Rojas, Maria Luz Zamudio, Wasyl, Dariusz, Bosevska, Golubinka, Kochubovski, Mihail, Radu, Cojocaru, Gassama, Amy, Radosavljević, Vladimir, Wuertz, Stefan, Zuniga-Montanez, Rogelio, Tay, Moon Y. F., Gavacova, Dagmar, Pastuchova, Katarina, Truska, Peter, Trkov, Marija, Esterhuyse, Kerneels, Keddy, Karen, Cerda-Cuellar, Marta, Pathirage, Sujatha, Norrgren, Leif, Orn, Stefan, Larsson, D. G. Joakim, Van der Heijden, Tanja, Kumburu, Happiness Houka, Sanneh, Bakary, Bidjada, Pawou, Njanpop-Lafourcade, Berthe-Marie, Nikiema-Pessinaba, Somtinda Christelle, Levent, Belkis, Meschke, John Scott, Beck, Nicola Koren, Chinh, Dang Van, Nguyen, Do Phuc, Doan Minh Nguyen, Tran, Kwenda, Geoffrey, Tabo, Djim-Adjim, Wester, Astrid Louise, Cuadros-Orellana, Sara, "Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage" in Nature Communications, 10 (2019), https://doi.org/10.1038/s41467-019-08853-3 ., conv_363 .