Uloga Harderove žlezde u imunom odgovoru pilića sa maternalnim imunitetom na vakcinu protiv virusnog infektivnog bronhitisa
Role of Harderian gland in immune response of chickens with maternal immunity to vaccine against infectious bronchitis virus
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2012
Authors
Spalević, Ljiljana![](/themes/Miragereponivs/images/orcid.png)
Ivetić, Vojin
Jakić-Dimić, Dobrila
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Maslić-Strižak, Danka
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Potkonjak, Aleksandar
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Pavlović, Nikola
Article (Published version)
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U ovom radu je ispitivana uloga Harderove žlezde u imunološkom odgovoru nakon vakcinacije protiv infektivnog bronhitisa (IB). Ogledom je obuhvaćeno 100 brojlerskih pilića koji su podeljeni u dve grupe. Ogledna grupa vakcinisana je prvog dana starosti protiv infektivnog bronhitisa vakcinom Bronhivet I, koja sadrži živi atenuirani soj H120. Kontrolna grupa nije imunizovana. Ogled je trajao 21 dan. Ispitivani su krvni serumi 1, 7, 14. i 21. dana na prisustvo specifičnih antitela prema infektivnom bronhitisu (ELISA test). Praćene su histološke promene u građi Harderove žlezde u odnosu na primenjenu vakcinu. Ovim istraživanjem je dokazana uloga Harderove žlezde kao sekundarnog limfoidnog organa kod vakcinacije brojlerskih pilića protiv infektivnog bronhitisa. Prisutna maternalna antitela na IB nemaju negativan uticaj na vakcinaciju pilića prvog dana starosti. Vakcinalni virus delimično oštećuje Harderovu žlezdu.
In this study we investigated the role of the Harderian gland in the immune response following vaccination against infectious bronchitis (IB). The experiment was carried out on 100 broiler chicks which were divided into two experimental groups. Experimental group O was vaccinated on the first day of age against infectious bronchitis with vaccine Bronhivet I batches that contain a live attenuated strain H120 and the control group did not get immunized. The experiment lasted 21 days. Blood sera were examined on days 1, 7, 14 and 21 for the presence of specific antibodies against infectious bronchitis (ELISA test). Histological changes were observed in the structure of the Harderian gland in relation to the applied vaccine. This research demonstrated the role of the Harderian gland as a secondary lymphoid organ in broiler vaccination against infectious bronchitis. Maternal antibodies present in the IB had no negative impact on the vaccination of chickens on the first day of age. The vacci...ne virus partially damaged the Harderian gland.
Keywords:
sekundarni limfoidni organ / maternalna antitela / infektivni bronhitis / Harderova žlezda / secondary lymphoid organ / maternal antibodies / infectious bronchitis / Harderian glandSource:
Veterinarski glasnik, 2012, 66, 3-4, 211-218Publisher:
- Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd
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Naučni institut za veterinarstvo SrbijeTY - JOUR AU - Spalević, Ljiljana AU - Ivetić, Vojin AU - Jakić-Dimić, Dobrila AU - Maslić-Strižak, Danka AU - Potkonjak, Aleksandar AU - Pavlović, Nikola PY - 2012 UR - https://reponivs.nivs.rs/handle/123456789/193 AB - U ovom radu je ispitivana uloga Harderove žlezde u imunološkom odgovoru nakon vakcinacije protiv infektivnog bronhitisa (IB). Ogledom je obuhvaćeno 100 brojlerskih pilića koji su podeljeni u dve grupe. Ogledna grupa vakcinisana je prvog dana starosti protiv infektivnog bronhitisa vakcinom Bronhivet I, koja sadrži živi atenuirani soj H120. Kontrolna grupa nije imunizovana. Ogled je trajao 21 dan. Ispitivani su krvni serumi 1, 7, 14. i 21. dana na prisustvo specifičnih antitela prema infektivnom bronhitisu (ELISA test). Praćene su histološke promene u građi Harderove žlezde u odnosu na primenjenu vakcinu. Ovim istraživanjem je dokazana uloga Harderove žlezde kao sekundarnog limfoidnog organa kod vakcinacije brojlerskih pilića protiv infektivnog bronhitisa. Prisutna maternalna antitela na IB nemaju negativan uticaj na vakcinaciju pilića prvog dana starosti. Vakcinalni virus delimično oštećuje Harderovu žlezdu. AB - In this study we investigated the role of the Harderian gland in the immune response following vaccination against infectious bronchitis (IB). The experiment was carried out on 100 broiler chicks which were divided into two experimental groups. Experimental group O was vaccinated on the first day of age against infectious bronchitis with vaccine Bronhivet I batches that contain a live attenuated strain H120 and the control group did not get immunized. The experiment lasted 21 days. Blood sera were examined on days 1, 7, 14 and 21 for the presence of specific antibodies against infectious bronchitis (ELISA test). Histological changes were observed in the structure of the Harderian gland in relation to the applied vaccine. This research demonstrated the role of the Harderian gland as a secondary lymphoid organ in broiler vaccination against infectious bronchitis. Maternal antibodies present in the IB had no negative impact on the vaccination of chickens on the first day of age. The vaccine virus partially damaged the Harderian gland. PB - Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd T2 - Veterinarski glasnik T1 - Uloga Harderove žlezde u imunom odgovoru pilića sa maternalnim imunitetom na vakcinu protiv virusnog infektivnog bronhitisa T1 - Role of Harderian gland in immune response of chickens with maternal immunity to vaccine against infectious bronchitis virus EP - 218 IS - 3-4 SP - 211 VL - 66 DO - 10.2298/VETGL1204211S UR - conv_94 ER -
@article{ author = "Spalević, Ljiljana and Ivetić, Vojin and Jakić-Dimić, Dobrila and Maslić-Strižak, Danka and Potkonjak, Aleksandar and Pavlović, Nikola", year = "2012", abstract = "U ovom radu je ispitivana uloga Harderove žlezde u imunološkom odgovoru nakon vakcinacije protiv infektivnog bronhitisa (IB). Ogledom je obuhvaćeno 100 brojlerskih pilića koji su podeljeni u dve grupe. Ogledna grupa vakcinisana je prvog dana starosti protiv infektivnog bronhitisa vakcinom Bronhivet I, koja sadrži živi atenuirani soj H120. Kontrolna grupa nije imunizovana. Ogled je trajao 21 dan. Ispitivani su krvni serumi 1, 7, 14. i 21. dana na prisustvo specifičnih antitela prema infektivnom bronhitisu (ELISA test). Praćene su histološke promene u građi Harderove žlezde u odnosu na primenjenu vakcinu. Ovim istraživanjem je dokazana uloga Harderove žlezde kao sekundarnog limfoidnog organa kod vakcinacije brojlerskih pilića protiv infektivnog bronhitisa. Prisutna maternalna antitela na IB nemaju negativan uticaj na vakcinaciju pilića prvog dana starosti. Vakcinalni virus delimično oštećuje Harderovu žlezdu., In this study we investigated the role of the Harderian gland in the immune response following vaccination against infectious bronchitis (IB). The experiment was carried out on 100 broiler chicks which were divided into two experimental groups. Experimental group O was vaccinated on the first day of age against infectious bronchitis with vaccine Bronhivet I batches that contain a live attenuated strain H120 and the control group did not get immunized. The experiment lasted 21 days. Blood sera were examined on days 1, 7, 14 and 21 for the presence of specific antibodies against infectious bronchitis (ELISA test). Histological changes were observed in the structure of the Harderian gland in relation to the applied vaccine. This research demonstrated the role of the Harderian gland as a secondary lymphoid organ in broiler vaccination against infectious bronchitis. Maternal antibodies present in the IB had no negative impact on the vaccination of chickens on the first day of age. The vaccine virus partially damaged the Harderian gland.", publisher = "Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd", journal = "Veterinarski glasnik", title = "Uloga Harderove žlezde u imunom odgovoru pilića sa maternalnim imunitetom na vakcinu protiv virusnog infektivnog bronhitisa, Role of Harderian gland in immune response of chickens with maternal immunity to vaccine against infectious bronchitis virus", pages = "218-211", number = "3-4", volume = "66", doi = "10.2298/VETGL1204211S", url = "conv_94" }
Spalević, L., Ivetić, V., Jakić-Dimić, D., Maslić-Strižak, D., Potkonjak, A.,& Pavlović, N.. (2012). Uloga Harderove žlezde u imunom odgovoru pilića sa maternalnim imunitetom na vakcinu protiv virusnog infektivnog bronhitisa. in Veterinarski glasnik Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd., 66(3-4), 211-218. https://doi.org/10.2298/VETGL1204211S conv_94
Spalević L, Ivetić V, Jakić-Dimić D, Maslić-Strižak D, Potkonjak A, Pavlović N. Uloga Harderove žlezde u imunom odgovoru pilića sa maternalnim imunitetom na vakcinu protiv virusnog infektivnog bronhitisa. in Veterinarski glasnik. 2012;66(3-4):211-218. doi:10.2298/VETGL1204211S conv_94 .
Spalević, Ljiljana, Ivetić, Vojin, Jakić-Dimić, Dobrila, Maslić-Strižak, Danka, Potkonjak, Aleksandar, Pavlović, Nikola, "Uloga Harderove žlezde u imunom odgovoru pilića sa maternalnim imunitetom na vakcinu protiv virusnog infektivnog bronhitisa" in Veterinarski glasnik, 66, no. 3-4 (2012):211-218, https://doi.org/10.2298/VETGL1204211S ., conv_94 .