Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1-Challenged Broiler Chickens
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2022
Аутори
Đurđević, Biljana![](/themes/Miragereponivs/images/orcid.png)
Pajić, Marko
![](/themes/Miragereponivs/images/orcid.png)
Knezević, Slobodan
![](/themes/Miragereponivs/images/orcid.png)
Polaček, Vladimir
Nešić, Ksenija
![](/themes/Miragereponivs/images/orcid.png)
Vucicević, Ivana
![](/themes/Miragereponivs/images/orcid.png)
Ostojić-Andrić, Dusica
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
This experiment was performed to investigate the protective eff ect of a new combined adsorbent (bentonite + yeast cell wall extract) previously tested in vitro, on the occurrence of pathological lesions in broilers fed a diet contaminated with aflatoxin B1 until 21 days of age. A total of 96 one-day old Ross 308 hybrid broiler chickens were divided into four groups: group I (control), group II (5 g/kg adsorbent), group III (5 g/kg adsorbent + 2 mg/kg aflatoxin B1), and group IV (2 mg/kg aflatoxin B1). Grossly, AFB1 and AFB1+adsorbent fed birds showed enlargement, friable texture of liver and enlargement and pallorness of kidneys. Spleen revealed size reduction. No gross-pathological changes were observed in control and group II. Histopathologically, lesions were observed in aflatoxicated groups. Liver revealed vacuolar cell degeneration, periportal and perivascular infiltration of mononuclear cells. Kidneys revealed mild to moderate degree of haemorrhages, tubular epithelial necrosis ...and infiltration of mononuclear cells along with heterophils. In group IV, catarrhal enteritis characterized by desquamation of epithelial cells were found in the duodenum. A milder form of gross and histopathological lesions was seen in group III. In conclusion, the present study revealed that supplementation of a new combined toxin binder product in the concentration of 5 g/kg could not completely ameliorate afl atoxicity in broilers, although it met the stringent European regulation requirements for the minimum of 90% aflatoxin binding efficiency in in vitro study.
Кључне речи:
Pathological lesions / Broilers / Aflatoxin B1 / AdsorbentИзвор:
Kafkas Universitesi Veteriner Fakultesi Dergisi, 2022, 28, 2, 185-191Издавач:
- Kafkas Univ, Veteriner Fakultesi Dergisi, Kars
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200031 (Научни институт за ветеринарство 'Нови Сад', Нови Сад) (RS-MESTD-inst-2020-200031)
- Inovation Fund of the Republic of Serbia [721]
DOI: 10.9775/kvfd.2021.26654
ISSN: 1300-6045
WoS: 000744658000001
Scopus: 2-s2.0-85127980664
Институција/група
Naučni institut za veterinarstvo SrbijeTY - JOUR AU - Đurđević, Biljana AU - Pajić, Marko AU - Knezević, Slobodan AU - Polaček, Vladimir AU - Nešić, Ksenija AU - Vucicević, Ivana AU - Ostojić-Andrić, Dusica PY - 2022 UR - https://reponivs.nivs.rs/handle/123456789/482 AB - This experiment was performed to investigate the protective eff ect of a new combined adsorbent (bentonite + yeast cell wall extract) previously tested in vitro, on the occurrence of pathological lesions in broilers fed a diet contaminated with aflatoxin B1 until 21 days of age. A total of 96 one-day old Ross 308 hybrid broiler chickens were divided into four groups: group I (control), group II (5 g/kg adsorbent), group III (5 g/kg adsorbent + 2 mg/kg aflatoxin B1), and group IV (2 mg/kg aflatoxin B1). Grossly, AFB1 and AFB1+adsorbent fed birds showed enlargement, friable texture of liver and enlargement and pallorness of kidneys. Spleen revealed size reduction. No gross-pathological changes were observed in control and group II. Histopathologically, lesions were observed in aflatoxicated groups. Liver revealed vacuolar cell degeneration, periportal and perivascular infiltration of mononuclear cells. Kidneys revealed mild to moderate degree of haemorrhages, tubular epithelial necrosis and infiltration of mononuclear cells along with heterophils. In group IV, catarrhal enteritis characterized by desquamation of epithelial cells were found in the duodenum. A milder form of gross and histopathological lesions was seen in group III. In conclusion, the present study revealed that supplementation of a new combined toxin binder product in the concentration of 5 g/kg could not completely ameliorate afl atoxicity in broilers, although it met the stringent European regulation requirements for the minimum of 90% aflatoxin binding efficiency in in vitro study. PB - Kafkas Univ, Veteriner Fakultesi Dergisi, Kars T2 - Kafkas Universitesi Veteriner Fakultesi Dergisi T1 - Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1-Challenged Broiler Chickens EP - 191 IS - 2 SP - 185 VL - 28 DO - 10.9775/kvfd.2021.26654 UR - conv_580 ER -
@article{ author = "Đurđević, Biljana and Pajić, Marko and Knezević, Slobodan and Polaček, Vladimir and Nešić, Ksenija and Vucicević, Ivana and Ostojić-Andrić, Dusica", year = "2022", abstract = "This experiment was performed to investigate the protective eff ect of a new combined adsorbent (bentonite + yeast cell wall extract) previously tested in vitro, on the occurrence of pathological lesions in broilers fed a diet contaminated with aflatoxin B1 until 21 days of age. A total of 96 one-day old Ross 308 hybrid broiler chickens were divided into four groups: group I (control), group II (5 g/kg adsorbent), group III (5 g/kg adsorbent + 2 mg/kg aflatoxin B1), and group IV (2 mg/kg aflatoxin B1). Grossly, AFB1 and AFB1+adsorbent fed birds showed enlargement, friable texture of liver and enlargement and pallorness of kidneys. Spleen revealed size reduction. No gross-pathological changes were observed in control and group II. Histopathologically, lesions were observed in aflatoxicated groups. Liver revealed vacuolar cell degeneration, periportal and perivascular infiltration of mononuclear cells. Kidneys revealed mild to moderate degree of haemorrhages, tubular epithelial necrosis and infiltration of mononuclear cells along with heterophils. In group IV, catarrhal enteritis characterized by desquamation of epithelial cells were found in the duodenum. A milder form of gross and histopathological lesions was seen in group III. In conclusion, the present study revealed that supplementation of a new combined toxin binder product in the concentration of 5 g/kg could not completely ameliorate afl atoxicity in broilers, although it met the stringent European regulation requirements for the minimum of 90% aflatoxin binding efficiency in in vitro study.", publisher = "Kafkas Univ, Veteriner Fakultesi Dergisi, Kars", journal = "Kafkas Universitesi Veteriner Fakultesi Dergisi", title = "Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1-Challenged Broiler Chickens", pages = "191-185", number = "2", volume = "28", doi = "10.9775/kvfd.2021.26654", url = "conv_580" }
Đurđević, B., Pajić, M., Knezević, S., Polaček, V., Nešić, K., Vucicević, I.,& Ostojić-Andrić, D.. (2022). Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1-Challenged Broiler Chickens. in Kafkas Universitesi Veteriner Fakultesi Dergisi Kafkas Univ, Veteriner Fakultesi Dergisi, Kars., 28(2), 185-191. https://doi.org/10.9775/kvfd.2021.26654 conv_580
Đurđević B, Pajić M, Knezević S, Polaček V, Nešić K, Vucicević I, Ostojić-Andrić D. Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1-Challenged Broiler Chickens. in Kafkas Universitesi Veteriner Fakultesi Dergisi. 2022;28(2):185-191. doi:10.9775/kvfd.2021.26654 conv_580 .
Đurđević, Biljana, Pajić, Marko, Knezević, Slobodan, Polaček, Vladimir, Nešić, Ksenija, Vucicević, Ivana, Ostojić-Andrić, Dusica, "Evaluation of the Effects of New Combined Adsorbent on Occurrence of Pathological Lesions in Aflatoxin B1-Challenged Broiler Chickens" in Kafkas Universitesi Veteriner Fakultesi Dergisi, 28, no. 2 (2022):185-191, https://doi.org/10.9775/kvfd.2021.26654 ., conv_580 .