Toxicity of high uranium doses in broilers and protection with mineral adsorbents
Само за регистроване кориснике
2019
Аутори
Mitrović, Branislava![](/themes/Miragereponivs/images/orcid.png)
Stojanović, Mirjana
![](/themes/Miragereponivs/images/orcid.png)
Sekulić, Zivko
Andrić, Velibor
![](/themes/Miragereponivs/images/orcid.png)
Vićentijević, Mihajlo
![](/themes/Miragereponivs/images/orcid.png)
Vranjes, Borjana
![](/themes/Miragereponivs/images/orcid.png)
Чланак у часопису (Објављена верзија)
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Метаподаци
Приказ свих података о документуАпстракт
The aim of this study was to determine the uranium distribution and histopathological changes in broiler organs (kidney, liver, and brain) and muscle after 7 days of contamination with high doses of uranyl nitrate hexahydrate (UN), and the protective efficiency of three different mineral adsorbents (organobentonite, organozeolite, and sepiolite). During the 7 days, the UN administration was 50mg per day, and administration of adsorbents was 2g per day immediately after UN. In control group where broilers received only UN, histopathological changes such as necrosis of intestinal villi, oedema, vacuolisation and abruption of epithelial cells in renal tubules, oedema and vacuolisation of the cytoplasm of hepatocytes, and dystrophic changes in the neurons of the medulla oblongata were observed. In contrast, when the adsorbents organobentonite, organozeolite, and sepiolite were administered, no histopathological changes were observed in liver and brain. The investigated adsorbents showed th...e highest protective effects in liver (80-92%), compared to the kidney (77-86%), brain (37-64%), and meat (31-63%).
Кључне речи:
Uranyl nitrate / Toxicity / Histopathological changes / Broilers / AdsorbentsИзвор:
Radiation and Environmental Biophysics, 2019, 58, 3, 385-391Издавач:
- Springer, New York
Финансирање / пројекти:
- Развој технологија и производа на бази минералних сировина и отпадне биомасе у циљу заштите ресурса за производњу безбедне хране (RS-MESTD-Technological Development (TD or TR)-31003)
- Освајање технолошких поступака добијања еколошких материјала на бази неметаличних минералних сировина (RS-MESTD-Technological Development (TD or TR)-34013)
DOI: 10.1007/s00411-019-00790-5
ISSN: 0301-634X
PubMed: 30972493
WoS: 000474439000007
Scopus: 2-s2.0-85068765195
Институција/група
Naučni institut za veterinarstvo SrbijeTY - JOUR AU - Mitrović, Branislava AU - Stojanović, Mirjana AU - Sekulić, Zivko AU - Andrić, Velibor AU - Vićentijević, Mihajlo AU - Vranjes, Borjana PY - 2019 UR - https://reponivs.nivs.rs/handle/123456789/397 AB - The aim of this study was to determine the uranium distribution and histopathological changes in broiler organs (kidney, liver, and brain) and muscle after 7 days of contamination with high doses of uranyl nitrate hexahydrate (UN), and the protective efficiency of three different mineral adsorbents (organobentonite, organozeolite, and sepiolite). During the 7 days, the UN administration was 50mg per day, and administration of adsorbents was 2g per day immediately after UN. In control group where broilers received only UN, histopathological changes such as necrosis of intestinal villi, oedema, vacuolisation and abruption of epithelial cells in renal tubules, oedema and vacuolisation of the cytoplasm of hepatocytes, and dystrophic changes in the neurons of the medulla oblongata were observed. In contrast, when the adsorbents organobentonite, organozeolite, and sepiolite were administered, no histopathological changes were observed in liver and brain. The investigated adsorbents showed the highest protective effects in liver (80-92%), compared to the kidney (77-86%), brain (37-64%), and meat (31-63%). PB - Springer, New York T2 - Radiation and Environmental Biophysics T1 - Toxicity of high uranium doses in broilers and protection with mineral adsorbents EP - 391 IS - 3 SP - 385 VL - 58 DO - 10.1007/s00411-019-00790-5 UR - conv_525 ER -
@article{ author = "Mitrović, Branislava and Stojanović, Mirjana and Sekulić, Zivko and Andrić, Velibor and Vićentijević, Mihajlo and Vranjes, Borjana", year = "2019", abstract = "The aim of this study was to determine the uranium distribution and histopathological changes in broiler organs (kidney, liver, and brain) and muscle after 7 days of contamination with high doses of uranyl nitrate hexahydrate (UN), and the protective efficiency of three different mineral adsorbents (organobentonite, organozeolite, and sepiolite). During the 7 days, the UN administration was 50mg per day, and administration of adsorbents was 2g per day immediately after UN. In control group where broilers received only UN, histopathological changes such as necrosis of intestinal villi, oedema, vacuolisation and abruption of epithelial cells in renal tubules, oedema and vacuolisation of the cytoplasm of hepatocytes, and dystrophic changes in the neurons of the medulla oblongata were observed. In contrast, when the adsorbents organobentonite, organozeolite, and sepiolite were administered, no histopathological changes were observed in liver and brain. The investigated adsorbents showed the highest protective effects in liver (80-92%), compared to the kidney (77-86%), brain (37-64%), and meat (31-63%).", publisher = "Springer, New York", journal = "Radiation and Environmental Biophysics", title = "Toxicity of high uranium doses in broilers and protection with mineral adsorbents", pages = "391-385", number = "3", volume = "58", doi = "10.1007/s00411-019-00790-5", url = "conv_525" }
Mitrović, B., Stojanović, M., Sekulić, Z., Andrić, V., Vićentijević, M.,& Vranjes, B.. (2019). Toxicity of high uranium doses in broilers and protection with mineral adsorbents. in Radiation and Environmental Biophysics Springer, New York., 58(3), 385-391. https://doi.org/10.1007/s00411-019-00790-5 conv_525
Mitrović B, Stojanović M, Sekulić Z, Andrić V, Vićentijević M, Vranjes B. Toxicity of high uranium doses in broilers and protection with mineral adsorbents. in Radiation and Environmental Biophysics. 2019;58(3):385-391. doi:10.1007/s00411-019-00790-5 conv_525 .
Mitrović, Branislava, Stojanović, Mirjana, Sekulić, Zivko, Andrić, Velibor, Vićentijević, Mihajlo, Vranjes, Borjana, "Toxicity of high uranium doses in broilers and protection with mineral adsorbents" in Radiation and Environmental Biophysics, 58, no. 3 (2019):385-391, https://doi.org/10.1007/s00411-019-00790-5 ., conv_525 .