TY  - CONF
AU  - Ninković, Milan
AU  - Žutić, Jadranka
AU  - Maksimović Zorić, Jelena
AU  - Jezdimirović, Nemanja
AU  - Milićević, Vesna
PY  - 2024-04-10
UR  - https://reponivs.nivs.rs/handle/123456789/974
AB  - Слинавка и шап (СиШ) спада у нарочито опасне заразне болести  домаћих папкара  и карактерише је веома нагло и брзо ширење. Болест се преноси директним и индиректним контактом. Вирус је јако отпоран у окружењу где је присутна болест и унутар исте фарме се може лако проширити путем различитих вектора, опреме и чак ветра. Циљ овог  рада је прикаже принципе и процедуре санитарних мера на газдинству у случају појаве Слинавке и Шапа. Важан сегмент сузбијања заразе јесте и дезинфекција зараженог газдинства, објеката, опреме, возила, отпадног и другог контаминираног материјала. Поштовање процедура чишћења, прања, дезинфекције су од виталног значаја за искорењивање СиШ на газдинству. Након уклањања лешева врши се прелиминарна дезинфекција газдинства. После 24 сата започиње се просес текућег чишћења и дезинфекције по завршетку дезинфекције, врши се одмор објекта у трајању од 7 дана при чему се врши завршно чишћење и дезинфекција објеката. Поновно усељевање животиња у објекте  могуће након укидања мера у зараженом и угроженој зони. Мере и начин ближег поступања на газдинству у случају су дефинисане правилником о утврђивању мера за рано откривање, дијагностику, спречавање ширења, сузбијање и искорењивање заразне болести Слинавке и Шап, "Службени гласник Републике Србије, 15/10".
AB  - Foot-and-mouth disease (FMD) is one of the particularly dangerous infectious diseases of domestic ungulates and is characterized by a very sudden and rapid spread. The disease is transmitted by direct and indirect contact. The virus is very resistant in the environment where the disease is present and within the same farm it can easily spread through different vectors, equipment and even wind. The aim of this work is to present the principles and procedures of sanitary measures on the farm in case of the occurrence of FMD. Disinfection of infected farms, facilities, equipment, vehicles, waste and other contaminated material is an important segment of infection control. Observance of cleaning, washing, disinfection procedures are of vital importance for the eradication of MFD on the farm. After removing the corpses, preliminary disinfection of the farm is carried out. After 24 hours, the process of ongoing cleaning and disinfection begins, after 7 days of rest, the final cleaning and disinfection of the facilities is carried out. Repopulation of animals into facilities is carried out after the lifting of measures in the infected and protective zone. The measures and method of closer treatment on the farm in the case are defined by the rulebook on establishing measures for early detection, diagnosis, prevention of spread, suppression and eradication of the infectious disease FMD, "Official Gazette of the Republic of Serbia, 15/10".
PB  - Beograd : Fakultet veterinarske medicine, Sekcija za zoonoze
C3  - XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
T1  - Примена санитарних мера на газдинству у случају појаве слинавке и шапа
T1  - Implementation of sanitary measures on the farm in the case of Foot and mouth disease
EP  - 111
SP  - 110
ER  - 

@conference{
author = "Ninković, Milan and Žutić, Jadranka and Maksimović Zorić, Jelena and Jezdimirović, Nemanja and Milićević, Vesna",
year = "2024-04-10",
abstract = "Слинавка и шап (СиШ) спада у нарочито опасне заразне болести  домаћих папкара  и карактерише је веома нагло и брзо ширење. Болест се преноси директним и индиректним контактом. Вирус је јако отпоран у окружењу где је присутна болест и унутар исте фарме се може лако проширити путем различитих вектора, опреме и чак ветра. Циљ овог  рада је прикаже принципе и процедуре санитарних мера на газдинству у случају појаве Слинавке и Шапа. Важан сегмент сузбијања заразе јесте и дезинфекција зараженог газдинства, објеката, опреме, возила, отпадног и другог контаминираног материјала. Поштовање процедура чишћења, прања, дезинфекције су од виталног значаја за искорењивање СиШ на газдинству. Након уклањања лешева врши се прелиминарна дезинфекција газдинства. После 24 сата започиње се просес текућег чишћења и дезинфекције по завршетку дезинфекције, врши се одмор објекта у трајању од 7 дана при чему се врши завршно чишћење и дезинфекција објеката. Поновно усељевање животиња у објекте  могуће након укидања мера у зараженом и угроженој зони. Мере и начин ближег поступања на газдинству у случају су дефинисане правилником о утврђивању мера за рано откривање, дијагностику, спречавање ширења, сузбијање и искорењивање заразне болести Слинавке и Шап, "Службени гласник Републике Србије, 15/10"., Foot-and-mouth disease (FMD) is one of the particularly dangerous infectious diseases of domestic ungulates and is characterized by a very sudden and rapid spread. The disease is transmitted by direct and indirect contact. The virus is very resistant in the environment where the disease is present and within the same farm it can easily spread through different vectors, equipment and even wind. The aim of this work is to present the principles and procedures of sanitary measures on the farm in case of the occurrence of FMD. Disinfection of infected farms, facilities, equipment, vehicles, waste and other contaminated material is an important segment of infection control. Observance of cleaning, washing, disinfection procedures are of vital importance for the eradication of MFD on the farm. After removing the corpses, preliminary disinfection of the farm is carried out. After 24 hours, the process of ongoing cleaning and disinfection begins, after 7 days of rest, the final cleaning and disinfection of the facilities is carried out. Repopulation of animals into facilities is carried out after the lifting of measures in the infected and protective zone. The measures and method of closer treatment on the farm in the case are defined by the rulebook on establishing measures for early detection, diagnosis, prevention of spread, suppression and eradication of the infectious disease FMD, "Official Gazette of the Republic of Serbia, 15/10".",
publisher = "Beograd : Fakultet veterinarske medicine, Sekcija za zoonoze",
journal = "XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.",
title = "Примена санитарних мера на газдинству у случају појаве слинавке и шапа, Implementation of sanitary measures on the farm in the case of Foot and mouth disease",
pages = "111-110"
}

Ninković, M., Žutić, J., Maksimović Zorić, J., Jezdimirović, N.,& Milićević, V.. (2024-04-10). Примена санитарних мера на газдинству у случају појаве слинавке и шапа. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
Beograd : Fakultet veterinarske medicine, Sekcija za zoonoze., 110-111.

Ninković M, Žutić J, Maksimović Zorić J, Jezdimirović N, Milićević V. Примена санитарних мера на газдинству у случају појаве слинавке и шапа. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.. 2024;:110-111..

Ninković, Milan, Žutić, Jadranka, Maksimović Zorić, Jelena, Jezdimirović, Nemanja, Milićević, Vesna, "Примена санитарних мера на газдинству у случају појаве слинавке и шапа" in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god. (2024-04-10):110-111.

TY  - CONF
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Branislav
AU  - Savić, Božidar
AU  - Milovanović, Bojan
AU  - Glišić, Dimitrije
AU  - Maletić, Jelena
AU  - Šolaja, Sofija
AU  - Milićević, Vesna
PY  - 2024
UR  - https://reponivs.nivs.rs/handle/123456789/952
AB  - Дивље свиње могу бити резервоари различитих бактерија, вируса и паразита и
могу се пренети на домаће свиње па и на људе индиректним или директним
контактом. Порцине цитомегаловирус (ПЦМВ) препознат је као главни
узрочник атрофичног ринитиса код свиња свих старосних категорија.
Међународни комитет за таксономију вируса (ИТЦВ) је порцине
цитомегаловирус сврстао у suid betaherpesvirus 2 (SuBHV2), и припада
подфамилији Betaherpesvirinae и фамилији Herpesviridae, али није сврстан ни у
један род. Генетска истраживања су показала да је ПЦМВ генетски сроднији
хуманим херпес вирусима (ХХВ) 6А, 6Б и 7. Поред тога, доказано је да ПЦМВ
доприноси репродуктивним проблемима код крмача и резултира раним
неонаталним губицима. Инфекција ПЦМВ-ом је раширена широм света и има
високу преваленцију, посебно у земљама са интензивном производњом свиња.
Клинички пролази непримећено због стеченог имунитета запата, и обично се
јавља код млађих категорија животиња. Нажалост, сама болест и инфекција су
углавном занемарени.
Како бисмо открили улогу дивљих свиња у епидемиологији ПЦМВ-а,
користили смо реал-тиме ПЦР тестирање 50 узорака (лимфни чвор, слезина и
бубрег) пореклом од одстрељених дивљих свиња.
Испитивање је потврдило присуство генома ПЦМВ у 4/50 (8%) узорака. Ови
резултати указују на релативно ниску али не и занемарљиву преваленцију
вируса у популацији дивљих свиња, што може да представља значајан ризик и
за популацију домаћих свиња.
AB  - Wild boars can be reservoirs of various bacteria, viruses, and parasites and can be
transmitted to domestic pigs and even humans through indirect or direct contact.
Porcine cytomegalovirus (PCMV) is recognized as the main cause of atrophic rhinitis
in pigs of all age categories. The International Committee on Taxonomy of Viruses
(ICTV) has classified porcine cytomegalovirus into suid betaherpesvirus 2
(SuBHV2), belonging to the subfamily Betaherpesvirinae and family Herpesviridae,
but it is not classified into any genus. Genetic research has shown that PCMV is
genetically closer to human herpes viruses (HHV) 6A, 6B, and 7. Additionally, it has
been proven that PCMV contributes to reproductive problems in sows and results in
early neonatal losses. PCMV infection is widespread worldwide and has a high
prevalence, especially in countries with intensive pig production. Clinically, it often
goes unnoticed due to acquired maternal immunity and usually occurs in younger
animal categories. Unfortunately, the disease itself and the infection are largely
neglected.
To discover the role of wild boars in PCMV epidemiology, we used real-time PCR
testing of 50 samples (lymph nodes, spleen, and kidney) originating from shot wild
boars.
Testing confirmed the presence of PCMV genome in 4 out of 50 (8%) samples. These
results indicate a relatively low but not negligible prevalence of the virus in the wild
boar population, which may pose a significant risk to the domestic pig population.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
T1  - Prva molekularna detekcija porcine citomegalovirusa kod divljih svinja u Srbiji
T1  - First molecular detection of porcine cytomegalovirus in wild boars in Serbia
EP  - 79
SP  - 78
ER  - 

@conference{
author = "Jezdimirović, Nemanja and Kureljušić, Branislav and Savić, Božidar and Milovanović, Bojan and Glišić, Dimitrije and Maletić, Jelena and Šolaja, Sofija and Milićević, Vesna",
year = "2024",
abstract = "Дивље свиње могу бити резервоари различитих бактерија, вируса и паразита и
могу се пренети на домаће свиње па и на људе индиректним или директним
контактом. Порцине цитомегаловирус (ПЦМВ) препознат је као главни
узрочник атрофичног ринитиса код свиња свих старосних категорија.
Међународни комитет за таксономију вируса (ИТЦВ) је порцине
цитомегаловирус сврстао у suid betaherpesvirus 2 (SuBHV2), и припада
подфамилији Betaherpesvirinae и фамилији Herpesviridae, али није сврстан ни у
један род. Генетска истраживања су показала да је ПЦМВ генетски сроднији
хуманим херпес вирусима (ХХВ) 6А, 6Б и 7. Поред тога, доказано је да ПЦМВ
доприноси репродуктивним проблемима код крмача и резултира раним
неонаталним губицима. Инфекција ПЦМВ-ом је раширена широм света и има
високу преваленцију, посебно у земљама са интензивном производњом свиња.
Клинички пролази непримећено због стеченог имунитета запата, и обично се
јавља код млађих категорија животиња. Нажалост, сама болест и инфекција су
углавном занемарени.
Како бисмо открили улогу дивљих свиња у епидемиологији ПЦМВ-а,
користили смо реал-тиме ПЦР тестирање 50 узорака (лимфни чвор, слезина и
бубрег) пореклом од одстрељених дивљих свиња.
Испитивање је потврдило присуство генома ПЦМВ у 4/50 (8%) узорака. Ови
резултати указују на релативно ниску али не и занемарљиву преваленцију
вируса у популацији дивљих свиња, што може да представља значајан ризик и
за популацију домаћих свиња., Wild boars can be reservoirs of various bacteria, viruses, and parasites and can be
transmitted to domestic pigs and even humans through indirect or direct contact.
Porcine cytomegalovirus (PCMV) is recognized as the main cause of atrophic rhinitis
in pigs of all age categories. The International Committee on Taxonomy of Viruses
(ICTV) has classified porcine cytomegalovirus into suid betaherpesvirus 2
(SuBHV2), belonging to the subfamily Betaherpesvirinae and family Herpesviridae,
but it is not classified into any genus. Genetic research has shown that PCMV is
genetically closer to human herpes viruses (HHV) 6A, 6B, and 7. Additionally, it has
been proven that PCMV contributes to reproductive problems in sows and results in
early neonatal losses. PCMV infection is widespread worldwide and has a high
prevalence, especially in countries with intensive pig production. Clinically, it often
goes unnoticed due to acquired maternal immunity and usually occurs in younger
animal categories. Unfortunately, the disease itself and the infection are largely
neglected.
To discover the role of wild boars in PCMV epidemiology, we used real-time PCR
testing of 50 samples (lymph nodes, spleen, and kidney) originating from shot wild
boars.
Testing confirmed the presence of PCMV genome in 4 out of 50 (8%) samples. These
results indicate a relatively low but not negligible prevalence of the virus in the wild
boar population, which may pose a significant risk to the domestic pig population.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.",
title = "Prva molekularna detekcija porcine citomegalovirusa kod divljih svinja u Srbiji, First molecular detection of porcine cytomegalovirus in wild boars in Serbia",
pages = "79-78"
}

Jezdimirović, N., Kureljušić, B., Savić, B., Milovanović, B., Glišić, D., Maletić, J., Šolaja, S.,& Milićević, V.. (2024). Prva molekularna detekcija porcine citomegalovirusa kod divljih svinja u Srbiji. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 78-79.

Jezdimirović N, Kureljušić B, Savić B, Milovanović B, Glišić D, Maletić J, Šolaja S, Milićević V. Prva molekularna detekcija porcine citomegalovirusa kod divljih svinja u Srbiji. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.. 2024;:78-79..

Jezdimirović, Nemanja, Kureljušić, Branislav, Savić, Božidar, Milovanović, Bojan, Glišić, Dimitrije, Maletić, Jelena, Šolaja, Sofija, Milićević, Vesna, "Prva molekularna detekcija porcine citomegalovirusa kod divljih svinja u Srbiji" in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god. (2024):78-79.

TY  - CONF
AU  - Savić, Božidar
AU  - Milićević, Vesna
AU  - Kureljušić, Branislav
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Maksimović Zorić, Jelena
AU  - Stevnčević, Ognjen
PY  - 2024
UR  - https://reponivs.nivs.rs/handle/123456789/953
AB  - Репродуктивни и респираторни синдром свиња (енгл. Porcine Reproductive and Respiratory
Syndrome – PRRS), је контагиозна вирусна афекција свиња која тренутно представља
економски најзначајније инфективно обољење свиња, ендемично у многим земљама у
свету укључујучи и нашу земљу. PRRS је узрокован са вирусом репродуктивног и
респираторног синдрома свиња (енгл. Porcine Reproductive and Respiratory Syndrome Virus
– PRRSV), а с краја 90-их година прошлог века, када је обољење по први пут
дијагностиковано у нашој земљи, постоји релативно ограничен број епидемиолошких
студија овог обољења и молекуларних истраживања овог вируса који циркулишу у
популацији свиња. Описана су два генотипа PRRSV: тип-1 или Европски тип (Lelystad -
прототип) и тип-2 или Амерички тип (VR-2332 – прототип). Од недавно, PRRSV тип-1 и
тип-2 су класификовани као две засебне врсте унутар рода Betaarterivirus и то као
Betaarterivirus suid 1 (PRRSV1) и Betaarterivirus suid 2 (PRRSV2). У оквиру генотипа 1
(PRRSV1) се разликују 4 генетске линије (подтипа) (1, 2, 3 и 4) у које су сврстани изолати
вируса пореклом из различитих географских региона Европе. Унутар подтипова 1 и 3, се
диференцирају кластери 1А-1Г и 3А-3Г док подтип 2 чини јединствена група изолата, без
дефинисаних кластера. У нашој земљи, PRRS је био искључиво узрокован генотипом 1
(PRRSV1), међутим, 2022 године, детектован је и генотип 2 вируса (PRRSV2), на фарми
која је вршила увоз свиња из Европске уније. Анализом генома овог вируса је установљено
да је најсличнији тзв. вакциналним-сојевима (vaccine-like strain), односно да је вирус
највероватније пореклом из вакцине (МLV PRRSV2 вакцина) која је употребљена за
имунизацију свиња против PRRSV2 у земљи извозници. Циљ овог истраживањ је био да
се установи генетски диверзитет изолата PRRSV1 пореклом са фарми свиња из наше земље
у периоду од 2012 до 2022 године. У ту сврху, извршено је секвенцирање 36 ОРФ5 гена
изолата PRRSV1 коришћењем Сангер методе, које су потом поређене и анализиране
заједно са 106 секвенци ОРФ5 гена PRRSV1 из генетских линија 1, 2 и 3, које репрезентују
комплетан спектар генетског диверзитета ових подтипова (секвенце кластера 1А-1Г, 3А-
3Г и линије 2), применом различитих модула са предефинисаним параметарима у оквиру
софтверских пакета CLC – MainWorkbench и Mega X. Прикупљене секвнеце ОРФ5 гена су
депоноване у „NCBI“ бази биоинформатичких података. Филогенетском анализом је
установљено да су сви изолати PRRSV1 детектовани у периооду од 2012 до 2022 године у
нашој земљи груписани у два подтипа, односно подтип 1 и 3. У оквиру линије 1, се налази
7 изолата и то: 2 изолата у кластеру 1А, 2 у кластеру 1Б, 2 у кластеру 1Д и један изолат у
кластеру 1Ф. У оквиру линије 2, 29 секвенци је груписано у кластер 3Ц. Добијени
резултати представљају важне информације за будуће епидемиолошке анализе PRRSV1
инфекције укључујући утврђивање повезаности односно сродности између изолата вируса,
поређење нових секвенци са секвенцама пореклом од вакциналних сојева вируса,
разликовање вакциналних од „дивљих“ сојева вируса и утврђивање „уноса“ нових вируса
у популацију. Оваква епидемиолошка истраживања треба искористити за установљавање
критичних тачака у биосигурносним мерама на конкретним фармама, те имплементирати
одговарајуће промене како би се PRRSV инфекција успешно превенирала и контролисала.
AB  - Porcine Reproductive and Respiratory Syndrome (PRRS) is a contagious viral disease
of swine that currently represents the most economically significant infectious disease
of pigs, endemic in many countries worldwide, including Serbia. PRRS is caused by the
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). Since the late 1990s,
when the disease was first diagnosed in the Serbia, there have been only few
epidemiological and molecular studies on circulating PPRS-viruses. Two genotypes of
PRRSV have been described: type 1 or European type (prototype Lelystad) and type 2
or American type (prototype VR-2332). Recently, PRRSV type 1 and type 2 have been
classified as two separate species within the genus Betaarterivirus, namely
Betaarterivirus suid 1 (PRRSV1) and Betaarterivirus suid 2 (PRRSV2). Within
genotype 1 (PRRSV1), four genetic lineages (subtypes) (1, 2, 3, and 4) have been
distinguished, in which isolates from different geographic regions of Europe are
classified. Within subtypes 1 and 3, clusters 1A-1G and 3A-3G are further differentiated,
while subtype 2 consists of a unique group of isolates, without defined clusters. In Serbia,
PRRS was exclusively caused by genotype 1 (PRRSV1); however, in 2022, a genotype
2 (PRRSV2) was detected on a farm that imported pigs from the European Union.
Genome analysis of this virus revealed its similarity to vaccine-like strains, indicating
that the virus most likely originated from a vaccine (MLV PRRSV2 vaccine) used for
immunization against PRRSV2 in the exporting country.
The aim of this study was to establish the genetic diversity of PRRSV1 isolates
originating from pig farms in Serbia from 2012 to 2022. For this purpose, sequencing of
36 ORF5 gene of PRRSV1 was performed using the Sanger method, which were then
compared and analyzed together with 106 ORF5 gene sequences of PRRSV1 from
genetic lineages 1, 2, and 3, representing the full range of genetic diversity of this
subtype (sequences from 1A-1G, 3A-3G clusters, and lineage 2), by using different
modules with predefined parameters within the software packages CLC –
MainWorkbench and Mega X. The obtained ORF5 gene sequences were deposited in the
NCBI database. Phylogenetic analysis revealed that all PRRSV1 isolates detected in the
Serbia from 2012 to 2022 were grouped into two subtypes, subtype 1 and 3. Within
lineage 1, there were 7 isolates: 2 in cluster 1A, 2 in cluster 1B, 2 in cluster 1D, and one
isolate in cluster 1F. Within lineage 2, 29 sequences were grouped in cluster 3C.
The obtained results provide important information for future epidemiological studies of
PRRSV1 infection, including the relatedness between isolates, comparing new obtianed
sequences with sequences originating from vaccine strains, differentiating vaccine
strains from "wild" strains, and determining the introduction of new strains into the
population. Such epidemiological studies can be used for find critical points in the
biosecurity on the given farms and implement changes in the others to prevent and
control PRRSV infection.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
T1  - Genetski diverzitet ORF5 gena virusa reproduktivnog i respiratornog sindroma svinja tip 1 od 2012 do 2022 godine
T1  - Genetic diversity of the ORF5 gene of type 1 porcine reproductive and respiratory syndrome virus in Serbia from 2012 to 2022
EP  - 103
SP  - 102
ER  - 

@conference{
author = "Savić, Božidar and Milićević, Vesna and Kureljušić, Branislav and Jezdimirović, Nemanja and Milovanović, Bojan and Maksimović Zorić, Jelena and Stevnčević, Ognjen",
year = "2024",
abstract = "Репродуктивни и респираторни синдром свиња (енгл. Porcine Reproductive and Respiratory
Syndrome – PRRS), је контагиозна вирусна афекција свиња која тренутно представља
економски најзначајније инфективно обољење свиња, ендемично у многим земљама у
свету укључујучи и нашу земљу. PRRS је узрокован са вирусом репродуктивног и
респираторног синдрома свиња (енгл. Porcine Reproductive and Respiratory Syndrome Virus
– PRRSV), а с краја 90-их година прошлог века, када је обољење по први пут
дијагностиковано у нашој земљи, постоји релативно ограничен број епидемиолошких
студија овог обољења и молекуларних истраживања овог вируса који циркулишу у
популацији свиња. Описана су два генотипа PRRSV: тип-1 или Европски тип (Lelystad -
прототип) и тип-2 или Амерички тип (VR-2332 – прототип). Од недавно, PRRSV тип-1 и
тип-2 су класификовани као две засебне врсте унутар рода Betaarterivirus и то као
Betaarterivirus suid 1 (PRRSV1) и Betaarterivirus suid 2 (PRRSV2). У оквиру генотипа 1
(PRRSV1) се разликују 4 генетске линије (подтипа) (1, 2, 3 и 4) у које су сврстани изолати
вируса пореклом из различитих географских региона Европе. Унутар подтипова 1 и 3, се
диференцирају кластери 1А-1Г и 3А-3Г док подтип 2 чини јединствена група изолата, без
дефинисаних кластера. У нашој земљи, PRRS је био искључиво узрокован генотипом 1
(PRRSV1), међутим, 2022 године, детектован је и генотип 2 вируса (PRRSV2), на фарми
која је вршила увоз свиња из Европске уније. Анализом генома овог вируса је установљено
да је најсличнији тзв. вакциналним-сојевима (vaccine-like strain), односно да је вирус
највероватније пореклом из вакцине (МLV PRRSV2 вакцина) која је употребљена за
имунизацију свиња против PRRSV2 у земљи извозници. Циљ овог истраживањ је био да
се установи генетски диверзитет изолата PRRSV1 пореклом са фарми свиња из наше земље
у периоду од 2012 до 2022 године. У ту сврху, извршено је секвенцирање 36 ОРФ5 гена
изолата PRRSV1 коришћењем Сангер методе, које су потом поређене и анализиране
заједно са 106 секвенци ОРФ5 гена PRRSV1 из генетских линија 1, 2 и 3, које репрезентују
комплетан спектар генетског диверзитета ових подтипова (секвенце кластера 1А-1Г, 3А-
3Г и линије 2), применом различитих модула са предефинисаним параметарима у оквиру
софтверских пакета CLC – MainWorkbench и Mega X. Прикупљене секвнеце ОРФ5 гена су
депоноване у „NCBI“ бази биоинформатичких података. Филогенетском анализом је
установљено да су сви изолати PRRSV1 детектовани у периооду од 2012 до 2022 године у
нашој земљи груписани у два подтипа, односно подтип 1 и 3. У оквиру линије 1, се налази
7 изолата и то: 2 изолата у кластеру 1А, 2 у кластеру 1Б, 2 у кластеру 1Д и један изолат у
кластеру 1Ф. У оквиру линије 2, 29 секвенци је груписано у кластер 3Ц. Добијени
резултати представљају важне информације за будуће епидемиолошке анализе PRRSV1
инфекције укључујући утврђивање повезаности односно сродности између изолата вируса,
поређење нових секвенци са секвенцама пореклом од вакциналних сојева вируса,
разликовање вакциналних од „дивљих“ сојева вируса и утврђивање „уноса“ нових вируса
у популацију. Оваква епидемиолошка истраживања треба искористити за установљавање
критичних тачака у биосигурносним мерама на конкретним фармама, те имплементирати
одговарајуће промене како би се PRRSV инфекција успешно превенирала и контролисала., Porcine Reproductive and Respiratory Syndrome (PRRS) is a contagious viral disease
of swine that currently represents the most economically significant infectious disease
of pigs, endemic in many countries worldwide, including Serbia. PRRS is caused by the
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). Since the late 1990s,
when the disease was first diagnosed in the Serbia, there have been only few
epidemiological and molecular studies on circulating PPRS-viruses. Two genotypes of
PRRSV have been described: type 1 or European type (prototype Lelystad) and type 2
or American type (prototype VR-2332). Recently, PRRSV type 1 and type 2 have been
classified as two separate species within the genus Betaarterivirus, namely
Betaarterivirus suid 1 (PRRSV1) and Betaarterivirus suid 2 (PRRSV2). Within
genotype 1 (PRRSV1), four genetic lineages (subtypes) (1, 2, 3, and 4) have been
distinguished, in which isolates from different geographic regions of Europe are
classified. Within subtypes 1 and 3, clusters 1A-1G and 3A-3G are further differentiated,
while subtype 2 consists of a unique group of isolates, without defined clusters. In Serbia,
PRRS was exclusively caused by genotype 1 (PRRSV1); however, in 2022, a genotype
2 (PRRSV2) was detected on a farm that imported pigs from the European Union.
Genome analysis of this virus revealed its similarity to vaccine-like strains, indicating
that the virus most likely originated from a vaccine (MLV PRRSV2 vaccine) used for
immunization against PRRSV2 in the exporting country.
The aim of this study was to establish the genetic diversity of PRRSV1 isolates
originating from pig farms in Serbia from 2012 to 2022. For this purpose, sequencing of
36 ORF5 gene of PRRSV1 was performed using the Sanger method, which were then
compared and analyzed together with 106 ORF5 gene sequences of PRRSV1 from
genetic lineages 1, 2, and 3, representing the full range of genetic diversity of this
subtype (sequences from 1A-1G, 3A-3G clusters, and lineage 2), by using different
modules with predefined parameters within the software packages CLC –
MainWorkbench and Mega X. The obtained ORF5 gene sequences were deposited in the
NCBI database. Phylogenetic analysis revealed that all PRRSV1 isolates detected in the
Serbia from 2012 to 2022 were grouped into two subtypes, subtype 1 and 3. Within
lineage 1, there were 7 isolates: 2 in cluster 1A, 2 in cluster 1B, 2 in cluster 1D, and one
isolate in cluster 1F. Within lineage 2, 29 sequences were grouped in cluster 3C.
The obtained results provide important information for future epidemiological studies of
PRRSV1 infection, including the relatedness between isolates, comparing new obtianed
sequences with sequences originating from vaccine strains, differentiating vaccine
strains from "wild" strains, and determining the introduction of new strains into the
population. Such epidemiological studies can be used for find critical points in the
biosecurity on the given farms and implement changes in the others to prevent and
control PRRSV infection.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.",
title = "Genetski diverzitet ORF5 gena virusa reproduktivnog i respiratornog sindroma svinja tip 1 od 2012 do 2022 godine, Genetic diversity of the ORF5 gene of type 1 porcine reproductive and respiratory syndrome virus in Serbia from 2012 to 2022",
pages = "103-102"
}

Savić, B., Milićević, V., Kureljušić, B., Jezdimirović, N., Milovanović, B., Maksimović Zorić, J.,& Stevnčević, O.. (2024). Genetski diverzitet ORF5 gena virusa reproduktivnog i respiratornog sindroma svinja tip 1 od 2012 do 2022 godine. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 102-103.

Savić B, Milićević V, Kureljušić B, Jezdimirović N, Milovanović B, Maksimović Zorić J, Stevnčević O. Genetski diverzitet ORF5 gena virusa reproduktivnog i respiratornog sindroma svinja tip 1 od 2012 do 2022 godine. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.. 2024;:102-103..

Savić, Božidar, Milićević, Vesna, Kureljušić, Branislav, Jezdimirović, Nemanja, Milovanović, Bojan, Maksimović Zorić, Jelena, Stevnčević, Ognjen, "Genetski diverzitet ORF5 gena virusa reproduktivnog i respiratornog sindroma svinja tip 1 od 2012 do 2022 godine" in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god. (2024):102-103.

TY  - CONF
AU  - Maksimović Zorić, Jelena
AU  - Veljović, Ljubiša
AU  - Glišić, Dimitrije
AU  - Kureljušić, Branislav
AU  - Jezdimirović, Nemanja
AU  - Stanojević, Slobodan
AU  - Maletić, Jelena
AU  - Ninković, Milan
AU  - Aksić, Đorđe
AU  - Savić, Božidar
PY  - 2024
UR  - https://reponivs.nivs.rs/handle/123456789/951
AB  - Афричка куга свиња (АКС) је први пут потврђена на територији Републике
Србије у јулу 2019. године, код домаћих свиња на епизоотиолошком подручју
Града Београда. Епизоотиолошким увиђајем је установљено да је неодговорно
понашање људи довело до уноса вируса из околних земаља и ширења заразе. У
првом таласу регистрована су жаришта у три насељена места, а применом
законом прописаних мера, болест је стављена под контролу и одјављена
децембра 2019. године. Упркос поновном уносу вируса из околних земаља и
ширењу заразе у популацијама дивљих и домаћих свиња у североисточним,
централним, источним и јужним деловима земље, ситуација на територији
епизоотиолошког подручја Града Београда у периоду од 2020. до 2022. године
је била стабилна. Поновно избијање заразе десило се 9. јуна 2023. године када
је болест потврђена код угинуле дивље свиње пронађене у ловишту
"Панчевачки рит", на територији општине Палилула. Већ 12. јуна потврђен је и
први случај код екстензивно узгајаних домаћих свиња у насљеном месту
Крњача. Зараза је убрзо потврђена и код дивљих свиња суседног ловишта "Рит"
и домаћих свиња других насељених места општине Палилула (Бесни Фок,
Дунавац, Јабучки Рит, Ковилово, Падинска Скела, Борча, Овча, Сланци, Велико
Село, Вишњица). У периоду од 9. јуна до 5. августа болест је потврђена на 157
газдинстава, односно код 223 домаће и код 110 дивљих свиња, те је посумњано
да су активности људи уз неадекватне биосигурносне мере на газдинствима
допринеле настанку епизоотије. Током јула и августа 2023. године зараза је
потврђена и код дивљих и домаћих свиња на територијама општина Земун,
Гроцка, Чукарица и Обреновац, где је регистровано 34 позитивна газдинстава и
једно ловиште. Од 26. септембра до 28. децембра није било нових случајева
заразе на епизоотиолошком подручју Града Београда, те је зараза одјављена 26.
децембра, односно 3 месеца после последњег потврђеног случаја АКС.
AB  - African swine fever (ASF) was first confirmed in the Republic of Serbia in July 2019,
in domestic pigs settled within the Belgrade epizootiology area. Through an
epizootiological investigation, it was concluded that the outbreak was a result of
irresponsible human behaviour which led to the introduction of the virus from
surrounding countries and its further spread. In the first wave, three outbreaks were
detected in three villages and by implementing regulatory measures for disease
control, the infection was successfully resolved in December 2019. Although the virus
re-entered from neighboring countries and spread across the northeast, central,
eastern, and southern regions, there were no new disease outbreaks in the Belgrade
epizootiological unit during the 2020-2022 period. Despite efforts to control the
infection, the disease reappeared in June 2023, spreading rapidly among wild boars
and domestic pigs in various settlements and hunting grounds of Palilula municipality.
During the two-month period, the disease was confirmed on 157 holdings,
respectively in 223 domestic pigs and 110 wild boars, implying the significance of
human behaviour and poor biosecurity measures on the epizootic spread of the
disease. During July and August 2023, the infection was confirmed in wild boars and
domestic pigs in the municipalities Zemun, Grocka, Čukarica, and Obrenovac, where
34 holdings and one hunting ground were declared positive. From September 26th to
December 28th, there were no new cases of infection in the Belgrade epizootiology
area, and the infection was resolved on December 26th, i.e. 3 months after the last
confirmed case of ASF.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
T1  - Afrička kuga svinja - epizootiološka situacija na teritoriji okruga grada Beograda u periodu od 2019. do 2023. godine
T1  - African swine fever - epizootiological situation in the Belgrade city area in the period from 2019 to 2023
EP  - 91
SP  - 90
ER  - 

@conference{
author = "Maksimović Zorić, Jelena and Veljović, Ljubiša and Glišić, Dimitrije and Kureljušić, Branislav and Jezdimirović, Nemanja and Stanojević, Slobodan and Maletić, Jelena and Ninković, Milan and Aksić, Đorđe and Savić, Božidar",
year = "2024",
abstract = "Афричка куга свиња (АКС) је први пут потврђена на територији Републике
Србије у јулу 2019. године, код домаћих свиња на епизоотиолошком подручју
Града Београда. Епизоотиолошким увиђајем је установљено да је неодговорно
понашање људи довело до уноса вируса из околних земаља и ширења заразе. У
првом таласу регистрована су жаришта у три насељена места, а применом
законом прописаних мера, болест је стављена под контролу и одјављена
децембра 2019. године. Упркос поновном уносу вируса из околних земаља и
ширењу заразе у популацијама дивљих и домаћих свиња у североисточним,
централним, источним и јужним деловима земље, ситуација на територији
епизоотиолошког подручја Града Београда у периоду од 2020. до 2022. године
је била стабилна. Поновно избијање заразе десило се 9. јуна 2023. године када
је болест потврђена код угинуле дивље свиње пронађене у ловишту
"Панчевачки рит", на територији општине Палилула. Већ 12. јуна потврђен је и
први случај код екстензивно узгајаних домаћих свиња у насљеном месту
Крњача. Зараза је убрзо потврђена и код дивљих свиња суседног ловишта "Рит"
и домаћих свиња других насељених места општине Палилула (Бесни Фок,
Дунавац, Јабучки Рит, Ковилово, Падинска Скела, Борча, Овча, Сланци, Велико
Село, Вишњица). У периоду од 9. јуна до 5. августа болест је потврђена на 157
газдинстава, односно код 223 домаће и код 110 дивљих свиња, те је посумњано
да су активности људи уз неадекватне биосигурносне мере на газдинствима
допринеле настанку епизоотије. Током јула и августа 2023. године зараза је
потврђена и код дивљих и домаћих свиња на територијама општина Земун,
Гроцка, Чукарица и Обреновац, где је регистровано 34 позитивна газдинстава и
једно ловиште. Од 26. септембра до 28. децембра није било нових случајева
заразе на епизоотиолошком подручју Града Београда, те је зараза одјављена 26.
децембра, односно 3 месеца после последњег потврђеног случаја АКС., African swine fever (ASF) was first confirmed in the Republic of Serbia in July 2019,
in domestic pigs settled within the Belgrade epizootiology area. Through an
epizootiological investigation, it was concluded that the outbreak was a result of
irresponsible human behaviour which led to the introduction of the virus from
surrounding countries and its further spread. In the first wave, three outbreaks were
detected in three villages and by implementing regulatory measures for disease
control, the infection was successfully resolved in December 2019. Although the virus
re-entered from neighboring countries and spread across the northeast, central,
eastern, and southern regions, there were no new disease outbreaks in the Belgrade
epizootiological unit during the 2020-2022 period. Despite efforts to control the
infection, the disease reappeared in June 2023, spreading rapidly among wild boars
and domestic pigs in various settlements and hunting grounds of Palilula municipality.
During the two-month period, the disease was confirmed on 157 holdings,
respectively in 223 domestic pigs and 110 wild boars, implying the significance of
human behaviour and poor biosecurity measures on the epizootic spread of the
disease. During July and August 2023, the infection was confirmed in wild boars and
domestic pigs in the municipalities Zemun, Grocka, Čukarica, and Obrenovac, where
34 holdings and one hunting ground were declared positive. From September 26th to
December 28th, there were no new cases of infection in the Belgrade epizootiology
area, and the infection was resolved on December 26th, i.e. 3 months after the last
confirmed case of ASF.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.",
title = "Afrička kuga svinja - epizootiološka situacija na teritoriji okruga grada Beograda u periodu od 2019. do 2023. godine, African swine fever - epizootiological situation in the Belgrade city area in the period from 2019 to 2023",
pages = "91-90"
}

Maksimović Zorić, J., Veljović, L., Glišić, D., Kureljušić, B., Jezdimirović, N., Stanojević, S., Maletić, J., Ninković, M., Aksić, Đ.,& Savić, B.. (2024). Afrička kuga svinja - epizootiološka situacija na teritoriji okruga grada Beograda u periodu od 2019. do 2023. godine. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 90-91.

Maksimović Zorić J, Veljović L, Glišić D, Kureljušić B, Jezdimirović N, Stanojević S, Maletić J, Ninković M, Aksić Đ, Savić B. Afrička kuga svinja - epizootiološka situacija na teritoriji okruga grada Beograda u periodu od 2019. do 2023. godine. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.. 2024;:90-91..

Maksimović Zorić, Jelena, Veljović, Ljubiša, Glišić, Dimitrije, Kureljušić, Branislav, Jezdimirović, Nemanja, Stanojević, Slobodan, Maletić, Jelena, Ninković, Milan, Aksić, Đorđe, Savić, Božidar, "Afrička kuga svinja - epizootiološka situacija na teritoriji okruga grada Beograda u periodu od 2019. do 2023. godine" in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god. (2024):90-91.

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Vićić, Ivan
AU  - Bradić, Milijana
AU  - Maletić, Jelena
AU  - Jezdimirović, Nemanja
AU  - Savić, Božidar
AU  - Milovanović, Bojan
AU  - Karabasil, Neđeljko
PY  - 2024
UR  - https://reponivs.nivs.rs/handle/123456789/955
AB  - Интензивирањем бројлерске производње дошло је до значајног повећања
преваленције различитих патолошких стања чија основна етиологија почива у
самом технолошком процесу производње. Појава контактног дерматитиса на
плантарној кожи екстремитета („foot pad dermatitis“), затим на скочном зглобу
(„hock burns“) и на грудима („breast burns“) данас представља врло раширену
појаву у интензивној производњи, наносећи значајне економске губитке услед
смањеног прираста и одбацивања трупова на линији клања. Поред интензивирања
бројлерске производње значајан утицај на њихову појаву имају исхрана, услови и
начин држања (врста простирке) и генетска предиспозиција. Најзначајнији
фактор ризика за настанак лезија је влажна простирка посебно у комбинацији са
штетним дејством амонијака. Појава лезија има веома велики значај као
индикатор добробити имајући у виду да постоје претпоставке да су установљене
лезије врло болне и да често онемогућавају нормално кретање пилића.
Макроскопским прегледом лезија на плантарној површини уочавају се
инфламаторне лезије праћене некрозом на јастучићима табана и/или на прстима.
Лезије се ређе могу установити на тибиометатарзалним зглобовима. Код благог
облика постоји дисколорација на кожи, хиперкератоза, а у тежим случајевима
јавња се едем, ерозије и улцерације.
Хистопатолошки, благе лезије се карактеришу умереном хиперплазијом и/или
хиперкератозом епидермиса, конгестијом и едемом, уз присуство благог
инфламаторног инфилтрата у форми периваскулитиса и субепителијалне
инфилтрације мононуклеарним ћелијама и мањим бројем гранулоцита. Умерене
суперфицијелне лезије се карактеришу врло израженом хиперплазијом и
хиперкератозом епидермиса, егзоцитозом, појавом пустула и красти, конгестијом
и инфилтрацијом дермиса мононуклеарним и гранулоцитиним инфилтратом.
Тешке, дубоке лезије се карактеришу некрозом епидермиса који је замењен
некротичним гнојним садржајем, појавом гранулационог ткива, израженом
инфламаторном инфилтрацијом (периваскулитис и субепителна инфилтрација)
доминантно хетерофилним гранулоцитима и мононуклеарним ћелијама.
Имајући у виду да је појава контактног дерматитиса све учесталија појава како на
фармама бројлерских пилића тако и на кланици приликом прегледа трупова на
линија клања неопходно је имплементирати програм контроле овог патолошког
стања и на тај начин побољшати добробит и обезбедити производњу квалитетног
и безбедног пилећег меса.
AB  - The intensification of broiler production has led to a significant increase in the
prevalence of various pathological conditions, whose basic etiology lies in the
production process itself. The occurrence of contact dermatitis on the plantar skin of
extremities ("foot pad dermatitis"), then on the hock joint ("hock burns"), and on the
breasts ("breast burns") is today a very widespread phenomenon in intensive production,
causing significant economic losses due to reduced growth and carcass rejection on the
slaughter line. In addition to the intensification of broiler production, significant factors
influencing their occurrence are nutrition, housing conditions (type of bedding), and
genetic predisposition. The most significant risk factor for lesion formation is wet
bedding, especially in combination with the harmful effects of ammonia. The
occurrence of lesions is very important as an indicator of welfare, considering that there
are assumptions that established lesions are very painful and often prevent normal
chicken movement. Macroscopic examination of lesions on the plantar surface reveals
inflammatory lesions accompanied by necrosis on the foot pads and/or toes. Lesions are
less commonly found on the tibiotarsal joints. In mild forms, discoloration of the skin,
hyperkeratosis, and in severe cases, edema, erosions, and ulcerations occur.
Histopathologically, mild lesions are characterized by moderate epidermal hyperplasia
and/or hyperkeratosis, congestion and edema, with the presence of mild inflammatory
infiltrate in the form of perivasculitis and subepithelial infiltration of mononuclear cells
and a small number of granulocytes. Moderate superficial lesions are characterized by
very pronounced epidermal hyperplasia and hyperkeratosis, exocytosis, appearance of
pustules and crusts, congestion, and infiltration of the dermis with mononuclear and
granulocytic infiltrate. Severe, deep lesions are characterized by epidermal necrosis
replaced by necrotic purulent content, appearance of granulation tissue, pronounced
inflammatory infiltration (perivasculitis and subepithelial infiltration) predominantly
with heterophilic granulocytes and mononuclear cells. Considering that the occurrence
of contact dermatitis is becoming more frequent both on broiler farms and in
slaughterhouses during carcass examination on the slaughter line, it is necessary to
implement a control program for this pathological condition
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
T1  - Kontaktni pododermatitis kod brojlerskih pilića – patološki aspekt -
T1  - Contact pododermatitis in broiler chickens – pathological aspect –
EP  - 147
SP  - 146
ER  - 

@conference{
author = "Kureljušić, Branislav and Vićić, Ivan and Bradić, Milijana and Maletić, Jelena and Jezdimirović, Nemanja and Savić, Božidar and Milovanović, Bojan and Karabasil, Neđeljko",
year = "2024",
abstract = "Интензивирањем бројлерске производње дошло је до значајног повећања
преваленције различитих патолошких стања чија основна етиологија почива у
самом технолошком процесу производње. Појава контактног дерматитиса на
плантарној кожи екстремитета („foot pad dermatitis“), затим на скочном зглобу
(„hock burns“) и на грудима („breast burns“) данас представља врло раширену
појаву у интензивној производњи, наносећи значајне економске губитке услед
смањеног прираста и одбацивања трупова на линији клања. Поред интензивирања
бројлерске производње значајан утицај на њихову појаву имају исхрана, услови и
начин држања (врста простирке) и генетска предиспозиција. Најзначајнији
фактор ризика за настанак лезија је влажна простирка посебно у комбинацији са
штетним дејством амонијака. Појава лезија има веома велики значај као
индикатор добробити имајући у виду да постоје претпоставке да су установљене
лезије врло болне и да често онемогућавају нормално кретање пилића.
Макроскопским прегледом лезија на плантарној површини уочавају се
инфламаторне лезије праћене некрозом на јастучићима табана и/или на прстима.
Лезије се ређе могу установити на тибиометатарзалним зглобовима. Код благог
облика постоји дисколорација на кожи, хиперкератоза, а у тежим случајевима
јавња се едем, ерозије и улцерације.
Хистопатолошки, благе лезије се карактеришу умереном хиперплазијом и/или
хиперкератозом епидермиса, конгестијом и едемом, уз присуство благог
инфламаторног инфилтрата у форми периваскулитиса и субепителијалне
инфилтрације мононуклеарним ћелијама и мањим бројем гранулоцита. Умерене
суперфицијелне лезије се карактеришу врло израженом хиперплазијом и
хиперкератозом епидермиса, егзоцитозом, појавом пустула и красти, конгестијом
и инфилтрацијом дермиса мононуклеарним и гранулоцитиним инфилтратом.
Тешке, дубоке лезије се карактеришу некрозом епидермиса који је замењен
некротичним гнојним садржајем, појавом гранулационог ткива, израженом
инфламаторном инфилтрацијом (периваскулитис и субепителна инфилтрација)
доминантно хетерофилним гранулоцитима и мононуклеарним ћелијама.
Имајући у виду да је појава контактног дерматитиса све учесталија појава како на
фармама бројлерских пилића тако и на кланици приликом прегледа трупова на
линија клања неопходно је имплементирати програм контроле овог патолошког
стања и на тај начин побољшати добробит и обезбедити производњу квалитетног
и безбедног пилећег меса., The intensification of broiler production has led to a significant increase in the
prevalence of various pathological conditions, whose basic etiology lies in the
production process itself. The occurrence of contact dermatitis on the plantar skin of
extremities ("foot pad dermatitis"), then on the hock joint ("hock burns"), and on the
breasts ("breast burns") is today a very widespread phenomenon in intensive production,
causing significant economic losses due to reduced growth and carcass rejection on the
slaughter line. In addition to the intensification of broiler production, significant factors
influencing their occurrence are nutrition, housing conditions (type of bedding), and
genetic predisposition. The most significant risk factor for lesion formation is wet
bedding, especially in combination with the harmful effects of ammonia. The
occurrence of lesions is very important as an indicator of welfare, considering that there
are assumptions that established lesions are very painful and often prevent normal
chicken movement. Macroscopic examination of lesions on the plantar surface reveals
inflammatory lesions accompanied by necrosis on the foot pads and/or toes. Lesions are
less commonly found on the tibiotarsal joints. In mild forms, discoloration of the skin,
hyperkeratosis, and in severe cases, edema, erosions, and ulcerations occur.
Histopathologically, mild lesions are characterized by moderate epidermal hyperplasia
and/or hyperkeratosis, congestion and edema, with the presence of mild inflammatory
infiltrate in the form of perivasculitis and subepithelial infiltration of mononuclear cells
and a small number of granulocytes. Moderate superficial lesions are characterized by
very pronounced epidermal hyperplasia and hyperkeratosis, exocytosis, appearance of
pustules and crusts, congestion, and infiltration of the dermis with mononuclear and
granulocytic infiltrate. Severe, deep lesions are characterized by epidermal necrosis
replaced by necrotic purulent content, appearance of granulation tissue, pronounced
inflammatory infiltration (perivasculitis and subepithelial infiltration) predominantly
with heterophilic granulocytes and mononuclear cells. Considering that the occurrence
of contact dermatitis is becoming more frequent both on broiler farms and in
slaughterhouses during carcass examination on the slaughter line, it is necessary to
implement a control program for this pathological condition",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.",
title = "Kontaktni pododermatitis kod brojlerskih pilića – patološki aspekt -, Contact pododermatitis in broiler chickens – pathological aspect –",
pages = "147-146"
}

Kureljušić, B., Vićić, I., Bradić, M., Maletić, J., Jezdimirović, N., Savić, B., Milovanović, B.,& Karabasil, N.. (2024). Kontaktni pododermatitis kod brojlerskih pilića – patološki aspekt -. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 146-147.

Kureljušić B, Vićić I, Bradić M, Maletić J, Jezdimirović N, Savić B, Milovanović B, Karabasil N. Kontaktni pododermatitis kod brojlerskih pilića – patološki aspekt -. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.. 2024;:146-147..

Kureljušić, Branislav, Vićić, Ivan, Bradić, Milijana, Maletić, Jelena, Jezdimirović, Nemanja, Savić, Božidar, Milovanović, Bojan, Karabasil, Neđeljko, "Kontaktni pododermatitis kod brojlerskih pilića – patološki aspekt -" in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god. (2024):146-147.

TY  - CONF
AU  - Šolaja, Sofija
AU  - Glišić, Dimitrije
AU  - Zurovac Sapundžić, Zorana
AU  - Milovanović, Bojan
AU  - Maletić, Jelena
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Branislav
AU  - Milićević, Vesna
PY  - 2024
UR  - https://reponivs.nivs.rs/handle/123456789/954
AB  - Инфективне болести представљају један од главних проблема у интензивном узгоју свиња, упркос технолошком напретку и развоју биосигурносних мера. Вирусна респираторна обољења која имају највећи економски и здравствени значај у свињарству су репродуктивни и респираторни синдром свиња, инфлуенца свиња и Аујецкијева болест. Сеоска газдинства екстензивног типа, и даље предcтављају најчешћи начин узгоја свиња у Србији. Циљ истраживања је био да се утврди серопреваленција респираторних вируса на сеоским газдинствима која представљају извор патогена за комерцијалне фарме. Крвни серуми су узорковани од 222 јединке са 69 газдинстава на којима се налазило до 10 свиња. За детекцију антитела су коришћени комерцијални ЕЛИСА тестови према упутству произвођача. Установљено је 38 (17,1%) серопозитивних јединки на вирус Аујецкијеве болести и 6 (2,7%) на вирус репродуктивног и респираторног синдрома. Антитела на вирус инфлуенце свиња нису установљена ни код једне јединкe. Два газдинства (2,9%) су била серопозитивна на репродуктивни и респираторни синдром са серопреваленцијом у запату од 100%, без присуства антитела на друге тестиране вирусе. Проценат серопозитивних запата на Аујецкијеву болест је био 10,1%, а серопреваленција у запатима је варирала од 33% до 100%. Серонегативних запата на све три болести је било 48 (69,5%). Ови резултати указују да међу свињама на сеоским газдинствима највише циркулише вирус Аујецкијеве болести. Главне катактеристике сеоских газдинстава су неадекватне биосигурносне мере, исхрана помијама и неконтролисан транспорт и контакт са другим врстама животиња. Стога, будући да је здравствени статус оваквих запата непознат, они се сматрају извором високог ризика за комерцијалне фарме. Власници сеоских газдинстава су често запослени на комерцијалним фармама, без обзира на забрану држања свиња, и представљају везу између сеоских газдинстава и комерцијалних фарми. Неопходно је спровести мониторниг здравственог стања, побољшање биосигурносних мера и едукацију власника како би се спречило ширење инфективних обољења са сеоских газдинстава на комерцијалне фарме.
AB  - Infectious diseases represent one of the main challenges in intensive pig farming, despite technological advancements and biosecurity improvement. Viral respiratory diseases with the greatest economic and health significance in pig farming include porcine reproductive and respiratory syndrome (PRRS), swine influenza (SI), and Aujeszky's disease (AD). Small backyard farms continue to be the most common method of pig farming in Serbia. This research aimed to assess the prevalence of respiratory viruses on backyard farms, which serve as a source of pathogens for commercial farms. Serum samples were collected from 222 individuals on 69 farms, each housing up to 10 pigs. Commercial ELISA tests were used for antibody detection according to the manufacturer's instructions. Out of the samples, 38 (17.1%) were seropositive for AD, and 6 (2.7%) for PRRS. No antibodies to the swine influenza virus were detected. Two farms (2.9%) were seropositive for PRRS with a herd-level seroprevalence of 100%, with no antibodies detected for other tested viruses. The percentage of seropositive farms for Aujeszky's disease was 10.1%, with herd-level seroprevalence ranging from 33% to 100%. There were 48 (69.5%) seronegative herds for all three diseases. These results indicate that Aujeszky's disease virus circulates the most among pigs on backyard farms. Main characteristics of backyard farms are low biosecurity, swill feeding, uncontrolled trade and contact with other animal species. Thus, since the health status of backyard farms is unknown, they are considered a high-risk infection source for commercial farms. Owners of backyard farms are often employed on commercial farms, despite regulations, serving as a link between backyard and commercial farms. Implementation of monitoring, improvement of biosecurity measures and education of owners are crucial steps for preventing the transmission of infectious diseases between backyard and commercial farms.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
T1  - Seroprevalencija virusnih respiratornih oboljenja svinja na seoskim gazdinstvima u Srbiji
T1  - Seroprevalence of viral respiratory diseases in swine backyard farms in Serbia
EP  - 107
SP  - 106
ER  - 

@conference{
author = "Šolaja, Sofija and Glišić, Dimitrije and Zurovac Sapundžić, Zorana and Milovanović, Bojan and Maletić, Jelena and Jezdimirović, Nemanja and Kureljušić, Branislav and Milićević, Vesna",
year = "2024",
abstract = "Инфективне болести представљају један од главних проблема у интензивном узгоју свиња, упркос технолошком напретку и развоју биосигурносних мера. Вирусна респираторна обољења која имају највећи економски и здравствени значај у свињарству су репродуктивни и респираторни синдром свиња, инфлуенца свиња и Аујецкијева болест. Сеоска газдинства екстензивног типа, и даље предcтављају најчешћи начин узгоја свиња у Србији. Циљ истраживања је био да се утврди серопреваленција респираторних вируса на сеоским газдинствима која представљају извор патогена за комерцијалне фарме. Крвни серуми су узорковани од 222 јединке са 69 газдинстава на којима се налазило до 10 свиња. За детекцију антитела су коришћени комерцијални ЕЛИСА тестови према упутству произвођача. Установљено је 38 (17,1%) серопозитивних јединки на вирус Аујецкијеве болести и 6 (2,7%) на вирус репродуктивног и респираторног синдрома. Антитела на вирус инфлуенце свиња нису установљена ни код једне јединкe. Два газдинства (2,9%) су била серопозитивна на репродуктивни и респираторни синдром са серопреваленцијом у запату од 100%, без присуства антитела на друге тестиране вирусе. Проценат серопозитивних запата на Аујецкијеву болест је био 10,1%, а серопреваленција у запатима је варирала од 33% до 100%. Серонегативних запата на све три болести је било 48 (69,5%). Ови резултати указују да међу свињама на сеоским газдинствима највише циркулише вирус Аујецкијеве болести. Главне катактеристике сеоских газдинстава су неадекватне биосигурносне мере, исхрана помијама и неконтролисан транспорт и контакт са другим врстама животиња. Стога, будући да је здравствени статус оваквих запата непознат, они се сматрају извором високог ризика за комерцијалне фарме. Власници сеоских газдинстава су често запослени на комерцијалним фармама, без обзира на забрану држања свиња, и представљају везу између сеоских газдинстава и комерцијалних фарми. Неопходно је спровести мониторниг здравственог стања, побољшање биосигурносних мера и едукацију власника како би се спречило ширење инфективних обољења са сеоских газдинстава на комерцијалне фарме., Infectious diseases represent one of the main challenges in intensive pig farming, despite technological advancements and biosecurity improvement. Viral respiratory diseases with the greatest economic and health significance in pig farming include porcine reproductive and respiratory syndrome (PRRS), swine influenza (SI), and Aujeszky's disease (AD). Small backyard farms continue to be the most common method of pig farming in Serbia. This research aimed to assess the prevalence of respiratory viruses on backyard farms, which serve as a source of pathogens for commercial farms. Serum samples were collected from 222 individuals on 69 farms, each housing up to 10 pigs. Commercial ELISA tests were used for antibody detection according to the manufacturer's instructions. Out of the samples, 38 (17.1%) were seropositive for AD, and 6 (2.7%) for PRRS. No antibodies to the swine influenza virus were detected. Two farms (2.9%) were seropositive for PRRS with a herd-level seroprevalence of 100%, with no antibodies detected for other tested viruses. The percentage of seropositive farms for Aujeszky's disease was 10.1%, with herd-level seroprevalence ranging from 33% to 100%. There were 48 (69.5%) seronegative herds for all three diseases. These results indicate that Aujeszky's disease virus circulates the most among pigs on backyard farms. Main characteristics of backyard farms are low biosecurity, swill feeding, uncontrolled trade and contact with other animal species. Thus, since the health status of backyard farms is unknown, they are considered a high-risk infection source for commercial farms. Owners of backyard farms are often employed on commercial farms, despite regulations, serving as a link between backyard and commercial farms. Implementation of monitoring, improvement of biosecurity measures and education of owners are crucial steps for preventing the transmission of infectious diseases between backyard and commercial farms.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.",
title = "Seroprevalencija virusnih respiratornih oboljenja svinja na seoskim gazdinstvima u Srbiji, Seroprevalence of viral respiratory diseases in swine backyard farms in Serbia",
pages = "107-106"
}

Šolaja, S., Glišić, D., Zurovac Sapundžić, Z., Milovanović, B., Maletić, J., Jezdimirović, N., Kureljušić, B.,& Milićević, V.. (2024). Seroprevalencija virusnih respiratornih oboljenja svinja na seoskim gazdinstvima u Srbiji. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 106-107.

Šolaja S, Glišić D, Zurovac Sapundžić Z, Milovanović B, Maletić J, Jezdimirović N, Kureljušić B, Milićević V. Seroprevalencija virusnih respiratornih oboljenja svinja na seoskim gazdinstvima u Srbiji. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.. 2024;:106-107..

Šolaja, Sofija, Glišić, Dimitrije, Zurovac Sapundžić, Zorana, Milovanović, Bojan, Maletić, Jelena, Jezdimirović, Nemanja, Kureljušić, Branislav, Milićević, Vesna, "Seroprevalencija virusnih respiratornih oboljenja svinja na seoskim gazdinstvima u Srbiji" in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god. (2024):106-107.

TY  - CONF
AU  - Ninković, Milan
AU  - Zdravković, Nemanja
AU  - Jezdimirović, Nemanja
AU  - Tasić, Aleksandra
AU  - Arsić, Sveta
AU  - Pavlović, Marija
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/819
AB  - The aim of this study was to evaluate the effect of fresh carrots nutritional supplementation
on the reproductive performance of Simmental cows. The usage of fresh carrots, which may
reach the β-carotene level of 200-1000 mg/kg, may positively affect reproductive
performance in cows, as beta-carotene is essential for the normal function of the reproductive
system. The experiment was carried out on twenty-four Simmental dairy cows, where 12
cows were supplementary fed with 5 kg carrots per cow/day from calving to the first artificial
insemination up to 75 days. Non-supplemented 12 cows served as a control group. All
observed cows were healthy. Reproductive performance was followed by estrus response,
conception rate, pregnancy percentage, calving percentage, and rate of embryonic survival.
All cows included in the survey were gynecologically ultrasound examined without
reproductive disorders. The results of the current study showed that cows in the experiment
group had higher estrus response and conception rates of 8.3% higher and embryonic survival
rates of 16.6% higher than the control group. We conclude that the nutritional
supplementation of fresh carrots in cows’ diets is stimulating and therefore recommended for
improved reproductive performance, which is attributed to higher β-carotene intake resulting
in better reproductive performance and reduced embryonic death rate.
PB  - East Sarajevo : Faculty of Agriculture
C3  - Book of abstracts : 14. International Scientific Agriculture Symposium "AGROSYM 2023", Jahorina, October 05-08, 2023
T1  - Effect of feeding with fresh carrots on reproductive performance of Simmental cows
EP  - 598
SP  - 598
ER  - 

@conference{
author = "Ninković, Milan and Zdravković, Nemanja and Jezdimirović, Nemanja and Tasić, Aleksandra and Arsić, Sveta and Pavlović, Marija",
year = "2023",
abstract = "The aim of this study was to evaluate the effect of fresh carrots nutritional supplementation
on the reproductive performance of Simmental cows. The usage of fresh carrots, which may
reach the β-carotene level of 200-1000 mg/kg, may positively affect reproductive
performance in cows, as beta-carotene is essential for the normal function of the reproductive
system. The experiment was carried out on twenty-four Simmental dairy cows, where 12
cows were supplementary fed with 5 kg carrots per cow/day from calving to the first artificial
insemination up to 75 days. Non-supplemented 12 cows served as a control group. All
observed cows were healthy. Reproductive performance was followed by estrus response,
conception rate, pregnancy percentage, calving percentage, and rate of embryonic survival.
All cows included in the survey were gynecologically ultrasound examined without
reproductive disorders. The results of the current study showed that cows in the experiment
group had higher estrus response and conception rates of 8.3% higher and embryonic survival
rates of 16.6% higher than the control group. We conclude that the nutritional
supplementation of fresh carrots in cows’ diets is stimulating and therefore recommended for
improved reproductive performance, which is attributed to higher β-carotene intake resulting
in better reproductive performance and reduced embryonic death rate.",
publisher = "East Sarajevo : Faculty of Agriculture",
journal = "Book of abstracts : 14. International Scientific Agriculture Symposium "AGROSYM 2023", Jahorina, October 05-08, 2023",
title = "Effect of feeding with fresh carrots on reproductive performance of Simmental cows",
pages = "598-598"
}

Ninković, M., Zdravković, N., Jezdimirović, N., Tasić, A., Arsić, S.,& Pavlović, M.. (2023). Effect of feeding with fresh carrots on reproductive performance of Simmental cows. in Book of abstracts : 14. International Scientific Agriculture Symposium "AGROSYM 2023", Jahorina, October 05-08, 2023
East Sarajevo : Faculty of Agriculture., 598-598.

Ninković M, Zdravković N, Jezdimirović N, Tasić A, Arsić S, Pavlović M. Effect of feeding with fresh carrots on reproductive performance of Simmental cows. in Book of abstracts : 14. International Scientific Agriculture Symposium "AGROSYM 2023", Jahorina, October 05-08, 2023. 2023;:598-598..

Ninković, Milan, Zdravković, Nemanja, Jezdimirović, Nemanja, Tasić, Aleksandra, Arsić, Sveta, Pavlović, Marija, "Effect of feeding with fresh carrots on reproductive performance of Simmental cows" in Book of abstracts : 14. International Scientific Agriculture Symposium "AGROSYM 2023", Jahorina, October 05-08, 2023 (2023):598-598.

TY  - CONF
AU  - Ninković, Milan
AU  - Zdravković, Nemanja
AU  - Žutić, Jadranka
AU  - Nikolić, Marko
AU  - Jezdimirović, Nemanja
AU  - Bojkovski, Jovan
AU  - Arsić, Sveta
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/651
AB  - Neonatalne dijareje teladi predstavljaju veoma značajan problem
koji u govedarskoj proizvodnji nanosi velike gubitke. Infektivna etiologija dijareja,
pre svega virusa Corona i Rota, otvaraju vrata enteropatogenim bakterijama izazivajući
atrofiju crevnih resica, oštećenje i citolizu enterocita, posledično dovodeći do
pojave maldigestije i malresopcije. Dijareje teladi su praćene profuznim sadržajem iz
creva, apatijom i dehidratacijom koje, komplikovane sekudarnom bakterijskom infekcijom,
mogu dovesti i do letalnog ishoda. Nastanku dijareja doprinosi nagomilavanje
osmotskih aktivnih materija zbog nemogućnosti razlaganja himusa u lumenu creva.
Usled inflamatornih procesa u digestivnom traktu, dolazi do poremećaja u procesu varenja
mleka i proizvodnje lab fermeta (himozina). Nesvareno mleko narušava osmotsku
koncentraciju u crevima što prouzrokuje transudaciju tečnosti u lumen i povećanje
zapremine tečnog sadržaja. On se ubrzano izbacuje što je klinički manifestovano pojavom
dijareje. Cilj ovog rada je prikaže efekte peroralne upotrebe 20% rastvora lab fermenta
(himozina) kao potpore u terapiji dijareja kod novorođene teladi. Lab ferment
u sirištu teleta ima ulogu u procesu formiranja gruša i postepenoj proteolizi, a samim
tim učestvuje u regulaciji osmotskog pritiska u crevima. Peroralnim davanjem 20% rastvora
lab fermenta, teladima koja imaju očuvan apetit, potpomaže se proces varenja
mleka i formiranja gruša. Zavisno od inteziteta dijareje, pored nadoknade tečnosti i antibiotske
terapije, upotreba 20% rastvora lab-fermenta je bila veoma uspešna u bržem
i efikasnijem uspostavljanju normalne konzistencije crevnog sadržaja. Takođe je zapaženo
da samostalna upotreba lab fermenta kod dijareja nastalih usled presisavanja teladi,
dovodi do skraćivanja njihovog trajanja.
AB  - Neonatal diarrhea in calves is a very significant problem that causes
large losses in cattle production. Infectious etiology of diarrhea, primarily Corona and
Rota viruses, open the door to enteropathogenic bacteria, causing atrophy of intestinal
villi, damage and cytolysis of enterocytes, consequently leading to mal - digestion and
mal - absorption. Diarrhea in calves is accompanied by profuse contents from the intestines,
apathy and dehydration, which, complicated by secondary bacterial infection,
can lead to a fatal outcome. The accumulation of osmotic active substances contributes
to the occurrence of diarrhea due to the impossibility of breaking down the chyme
in the intestinal lumen. Due to inflammatory processes in the digestive tract, there is a
disturbance in the process of milk digestion and the production of lab fermet (chymosin).
Undigested milk disrupts the osmotic concentration in the intestine, which causes
transudation of fluid into the lumen and an increase in the volume of the fluid content.
It is excreted rapidly, which is clinically manifested by the appearance of diarrhea.
The aim of this paper is to show the effects of oral use of a 20% solution of lab ferment
(chymosin) as a support in the treatment of diarrhea in newborn calves. Lab ferment
in calf rennet plays a role in the process of curd formation and gradual proteolysis, and
thus participates in the regulation of osmotic pressure in the intestines. By orally giving
a 20% solution of lab ferment to calves that have a preserved appetite, the process of
milk digestion and curd formation is supported. Depending on the intensity of the diarrhea,
in addition to fluid replacement and antibiotic therapy, the use of a 20% lab-ferment
solution was very successful in establishing the normal consistency of the intestinal
contents, faster and more efficiently. It has also been noted that the independent use
of lab ferment in diarrhea, caused by sucking calves leads to a shortening of the disease.
PB  - Beograd : Udruženje veterinara praktičara Srbije
C3  - 5. Simpozijum sa međunarodnim učešćem "Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda"
T1  - Primena lab fermenta (himozina) u terapiji neonatalnih dijareja teladi
T1  - Application of lab ferment (chymosin) in the therapy of neonatal calves diarrhea
EP  - 182
SP  - 181
ER  - 

@conference{
author = "Ninković, Milan and Zdravković, Nemanja and Žutić, Jadranka and Nikolić, Marko and Jezdimirović, Nemanja and Bojkovski, Jovan and Arsić, Sveta",
year = "2023",
abstract = "Neonatalne dijareje teladi predstavljaju veoma značajan problem
koji u govedarskoj proizvodnji nanosi velike gubitke. Infektivna etiologija dijareja,
pre svega virusa Corona i Rota, otvaraju vrata enteropatogenim bakterijama izazivajući
atrofiju crevnih resica, oštećenje i citolizu enterocita, posledično dovodeći do
pojave maldigestije i malresopcije. Dijareje teladi su praćene profuznim sadržajem iz
creva, apatijom i dehidratacijom koje, komplikovane sekudarnom bakterijskom infekcijom,
mogu dovesti i do letalnog ishoda. Nastanku dijareja doprinosi nagomilavanje
osmotskih aktivnih materija zbog nemogućnosti razlaganja himusa u lumenu creva.
Usled inflamatornih procesa u digestivnom traktu, dolazi do poremećaja u procesu varenja
mleka i proizvodnje lab fermeta (himozina). Nesvareno mleko narušava osmotsku
koncentraciju u crevima što prouzrokuje transudaciju tečnosti u lumen i povećanje
zapremine tečnog sadržaja. On se ubrzano izbacuje što je klinički manifestovano pojavom
dijareje. Cilj ovog rada je prikaže efekte peroralne upotrebe 20% rastvora lab fermenta
(himozina) kao potpore u terapiji dijareja kod novorođene teladi. Lab ferment
u sirištu teleta ima ulogu u procesu formiranja gruša i postepenoj proteolizi, a samim
tim učestvuje u regulaciji osmotskog pritiska u crevima. Peroralnim davanjem 20% rastvora
lab fermenta, teladima koja imaju očuvan apetit, potpomaže se proces varenja
mleka i formiranja gruša. Zavisno od inteziteta dijareje, pored nadoknade tečnosti i antibiotske
terapije, upotreba 20% rastvora lab-fermenta je bila veoma uspešna u bržem
i efikasnijem uspostavljanju normalne konzistencije crevnog sadržaja. Takođe je zapaženo
da samostalna upotreba lab fermenta kod dijareja nastalih usled presisavanja teladi,
dovodi do skraćivanja njihovog trajanja., Neonatal diarrhea in calves is a very significant problem that causes
large losses in cattle production. Infectious etiology of diarrhea, primarily Corona and
Rota viruses, open the door to enteropathogenic bacteria, causing atrophy of intestinal
villi, damage and cytolysis of enterocytes, consequently leading to mal - digestion and
mal - absorption. Diarrhea in calves is accompanied by profuse contents from the intestines,
apathy and dehydration, which, complicated by secondary bacterial infection,
can lead to a fatal outcome. The accumulation of osmotic active substances contributes
to the occurrence of diarrhea due to the impossibility of breaking down the chyme
in the intestinal lumen. Due to inflammatory processes in the digestive tract, there is a
disturbance in the process of milk digestion and the production of lab fermet (chymosin).
Undigested milk disrupts the osmotic concentration in the intestine, which causes
transudation of fluid into the lumen and an increase in the volume of the fluid content.
It is excreted rapidly, which is clinically manifested by the appearance of diarrhea.
The aim of this paper is to show the effects of oral use of a 20% solution of lab ferment
(chymosin) as a support in the treatment of diarrhea in newborn calves. Lab ferment
in calf rennet plays a role in the process of curd formation and gradual proteolysis, and
thus participates in the regulation of osmotic pressure in the intestines. By orally giving
a 20% solution of lab ferment to calves that have a preserved appetite, the process of
milk digestion and curd formation is supported. Depending on the intensity of the diarrhea,
in addition to fluid replacement and antibiotic therapy, the use of a 20% lab-ferment
solution was very successful in establishing the normal consistency of the intestinal
contents, faster and more efficiently. It has also been noted that the independent use
of lab ferment in diarrhea, caused by sucking calves leads to a shortening of the disease.",
publisher = "Beograd : Udruženje veterinara praktičara Srbije",
journal = "5. Simpozijum sa međunarodnim učešćem "Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda"",
title = "Primena lab fermenta (himozina) u terapiji neonatalnih dijareja teladi, Application of lab ferment (chymosin) in the therapy of neonatal calves diarrhea",
pages = "182-181"
}

Ninković, M., Zdravković, N., Žutić, J., Nikolić, M., Jezdimirović, N., Bojkovski, J.,& Arsić, S.. (2023). Primena lab fermenta (himozina) u terapiji neonatalnih dijareja teladi. in 5. Simpozijum sa međunarodnim učešćem "Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda"
Beograd : Udruženje veterinara praktičara Srbije., 181-182.

Ninković M, Zdravković N, Žutić J, Nikolić M, Jezdimirović N, Bojkovski J, Arsić S. Primena lab fermenta (himozina) u terapiji neonatalnih dijareja teladi. in 5. Simpozijum sa međunarodnim učešćem "Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda". 2023;:181-182..

Ninković, Milan, Zdravković, Nemanja, Žutić, Jadranka, Nikolić, Marko, Jezdimirović, Nemanja, Bojkovski, Jovan, Arsić, Sveta, "Primena lab fermenta (himozina) u terapiji neonatalnih dijareja teladi" in 5. Simpozijum sa međunarodnim učešćem "Zdravstvena zaštita i reprodukcija papkara, kopitara, živine i mesojeda" (2023):181-182.

TY  - CONF
AU  - Ninković, Milan
AU  - Zdravković, Nemanja
AU  - Nikolić, Marko
AU  - Pavlović, Marija
AU  - Jezdimirović, Nemanja
AU  - Zurovac Sapundžić, Zorana
AU  - Bojkovski, Jovan
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/599
AB  - Дијареје код  новорођених телади стварају велике проблеме стварајући велике економске губитке. Вирусни узрочници дијареја Корона и Рота вирус у првим данима живота доводе до тешких дијареја које се могу завршити угинућем телади. Вируси Рота и Корона отварају врата за секударне бактеријске узрочнике компликујући клиничку слику дијареје. У овом раду је приказан случај дијареја код телади проузроковани Рота вирусима и резултат вакцинације након случаја. Фарми 22 краве, сименталске расе током Јула 2022. године забележена су угинућа код 3 телета, старости од 5 до 12 дана, Поред примењене адекватне терапије, телад су брзо угињавала. Клиничка слика код оболелих телади је била акутног тока, изразитим профузним садржајем, са присутном дехидратацијом, апатијом. Поред тога, као значајан предиспонирајући фактор настанка дијареја јесте и топлотни стрес, где су дневне температуре се кретале и до 40 ℃. За дијагностичко испитивање узети су ректални брисеви од оболелих телади. Присуство Рота вируса у испитујућим брисевима потврђено је PCR методом. Због присутног проблема на фарми извршена је вакцинације свих гравидних крава у периоду 4-12 недеља пре очекиваног термина тељења комерцијално доступном вакцином. Применом вакцинације крава  у периоду засушења 4-12 недеље пре очекиваног тељења  против Kорона и Рота вируса постиже се адекватна пасивнa заштитa код новорођених телади. Резултати вакцинације високо стеоних крава огледа кроз смањење појаве дијареја, смањење стопе угинућа, смањење трошкова лечења,  као и смањене употребе антибиотика као најважнијег задатка у спречавања даљег раста антимикробне резистенције. Најважнији закључак из овог случаја је да појаве нових случајева дијареја ниje забележенo, значајно је смањена употреба антибиотика код телади који потичу од вакцинисаних крава, и у каснијим фазама одгоја таква телад су много мање имали здравствених проблема.
AB  - Diarrhea in newborn calves creates major problems, creating major economic losses. Viral causes of diarrhea Corona and Rota virus in the first days of life lead to severe diarrhea that can end in the death of calves. Rota and Corona viruses open the door for secondary bacterial agents, complicating the clinical picture of diarrhea. This paper presents a case of diarrhea in calves caused by Rota viruses and the result of vaccination after the case. On the farm of 20 cows, the Simmental breed, in July 2022, the deaths of 3 calves, aged from 5 to 12 days, were recorded. Despite the applied adequate therapy, the calves died quickly. The clinical picture in the affected calves was acute, with marked profuse content, with dehydration and apathy present. In addition, as a significant predisposing factor for the occurrence of diarrhea is heat stress, where daily temperatures ranged up to 40 ℃. Rectal swabs from sick calves were taken for diagnostic testing. The presence of Rotavirus in the test swabs was confirmed by the PCR method. Due to the current problem on the farm, all pregnant cows were vaccinated in the period 4-12 weeks before the expected calving date with a commercially available vaccine. Vaccination of cows during the drying period 4-12 weeks before the expected calving against Corona and Rotavirus achieves adequate passive immune protection in newborn calves. The results of vaccination of highly pregnant cows are reflected in the reduction of diarrhea, the reduction of death rates, the reduction of treatment costs, as well as the reduced use of antibiotics is the most important task in preventing the further growth of antimicrobial resistance. The most important conclusion from this case is that no new cases of diarrhea were recorded, the use of antibiotics in calves from vaccinated cows was significantly reduced, and in the later stages of rearing such calves had much fewer health problems.
PB  - Banja Luka : Veterinarska komora Republike Srpske
C3  - 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina)
T1  - Rota virusna dijareja teladi pre i posle vakcinacije - iskustvo
T1  - Rotaviruses diarrhea in calves before and after vaccination – experience
EP  - 70
SP  - 68
ER  - 

@conference{
author = "Ninković, Milan and Zdravković, Nemanja and Nikolić, Marko and Pavlović, Marija and Jezdimirović, Nemanja and Zurovac Sapundžić, Zorana and Bojkovski, Jovan",
year = "2023",
abstract = "Дијареје код  новорођених телади стварају велике проблеме стварајући велике економске губитке. Вирусни узрочници дијареја Корона и Рота вирус у првим данима живота доводе до тешких дијареја које се могу завршити угинућем телади. Вируси Рота и Корона отварају врата за секударне бактеријске узрочнике компликујући клиничку слику дијареје. У овом раду је приказан случај дијареја код телади проузроковани Рота вирусима и резултат вакцинације након случаја. Фарми 22 краве, сименталске расе током Јула 2022. године забележена су угинућа код 3 телета, старости од 5 до 12 дана, Поред примењене адекватне терапије, телад су брзо угињавала. Клиничка слика код оболелих телади је била акутног тока, изразитим профузним садржајем, са присутном дехидратацијом, апатијом. Поред тога, као значајан предиспонирајући фактор настанка дијареја јесте и топлотни стрес, где су дневне температуре се кретале и до 40 ℃. За дијагностичко испитивање узети су ректални брисеви од оболелих телади. Присуство Рота вируса у испитујућим брисевима потврђено је PCR методом. Због присутног проблема на фарми извршена је вакцинације свих гравидних крава у периоду 4-12 недеља пре очекиваног термина тељења комерцијално доступном вакцином. Применом вакцинације крава  у периоду засушења 4-12 недеље пре очекиваног тељења  против Kорона и Рота вируса постиже се адекватна пасивнa заштитa код новорођених телади. Резултати вакцинације високо стеоних крава огледа кроз смањење појаве дијареја, смањење стопе угинућа, смањење трошкова лечења,  као и смањене употребе антибиотика као најважнијег задатка у спречавања даљег раста антимикробне резистенције. Најважнији закључак из овог случаја је да појаве нових случајева дијареја ниje забележенo, значајно је смањена употреба антибиотика код телади који потичу од вакцинисаних крава, и у каснијим фазама одгоја таква телад су много мање имали здравствених проблема., Diarrhea in newborn calves creates major problems, creating major economic losses. Viral causes of diarrhea Corona and Rota virus in the first days of life lead to severe diarrhea that can end in the death of calves. Rota and Corona viruses open the door for secondary bacterial agents, complicating the clinical picture of diarrhea. This paper presents a case of diarrhea in calves caused by Rota viruses and the result of vaccination after the case. On the farm of 20 cows, the Simmental breed, in July 2022, the deaths of 3 calves, aged from 5 to 12 days, were recorded. Despite the applied adequate therapy, the calves died quickly. The clinical picture in the affected calves was acute, with marked profuse content, with dehydration and apathy present. In addition, as a significant predisposing factor for the occurrence of diarrhea is heat stress, where daily temperatures ranged up to 40 ℃. Rectal swabs from sick calves were taken for diagnostic testing. The presence of Rotavirus in the test swabs was confirmed by the PCR method. Due to the current problem on the farm, all pregnant cows were vaccinated in the period 4-12 weeks before the expected calving date with a commercially available vaccine. Vaccination of cows during the drying period 4-12 weeks before the expected calving against Corona and Rotavirus achieves adequate passive immune protection in newborn calves. The results of vaccination of highly pregnant cows are reflected in the reduction of diarrhea, the reduction of death rates, the reduction of treatment costs, as well as the reduced use of antibiotics is the most important task in preventing the further growth of antimicrobial resistance. The most important conclusion from this case is that no new cases of diarrhea were recorded, the use of antibiotics in calves from vaccinated cows was significantly reduced, and in the later stages of rearing such calves had much fewer health problems.",
publisher = "Banja Luka : Veterinarska komora Republike Srpske",
journal = "28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina)",
title = "Rota virusna dijareja teladi pre i posle vakcinacije - iskustvo, Rotaviruses diarrhea in calves before and after vaccination – experience",
pages = "70-68"
}

Ninković, M., Zdravković, N., Nikolić, M., Pavlović, M., Jezdimirović, N., Zurovac Sapundžić, Z.,& Bojkovski, J.. (2023). Rota virusna dijareja teladi pre i posle vakcinacije - iskustvo. in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina)
Banja Luka : Veterinarska komora Republike Srpske., 68-70.

Ninković M, Zdravković N, Nikolić M, Pavlović M, Jezdimirović N, Zurovac Sapundžić Z, Bojkovski J. Rota virusna dijareja teladi pre i posle vakcinacije - iskustvo. in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina). 2023;:68-70..

Ninković, Milan, Zdravković, Nemanja, Nikolić, Marko, Pavlović, Marija, Jezdimirović, Nemanja, Zurovac Sapundžić, Zorana, Bojkovski, Jovan, "Rota virusna dijareja teladi pre i posle vakcinacije - iskustvo" in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina) (2023):68-70.

TY  - CONF
AU  - Ninković, Milan
AU  - Zdravković, Nemanja
AU  - Jezdimirović, Nemanja
AU  - Žutić, Jadranka
AU  - Bojkovski, Jovan
AU  - Arsić, Sveta
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/789
AB  - Hemolaktija je klinički znak, koji označava prisustvo krvi u mleku. Dovodi do
pojave ekonomskih gubitaka zbog odbacivanja mleka i terapije obolelih krava.
Uobičajeni razlozi za nastanak hemolaktije su trauma vimena, ruptura krvnih sudova,
krvarenje usled dijapedeze, infektivna bolest (leptospiroza), trombocitopenija,
dijapedeza usled hiperemije posle porođaja, deficit vitamina. Patofiziologija
procesa i tačan uzrok njegovog nastanka nisu utvrđeni. Hemolaktija se može javiti
u bilo kojoj fazi laktacije, a najveći problem javljaju u prvim danima laktacije.
Prisustvo krvi u mleku narušava kvalitet kolostruma, što je od značaja za novorođenu
telad. Cilj ovog rada bio je da ukaže na pojavu hemolaktije kod mlečnih krava.
Dugotrajno praćenje pojave hemolaktije ukazuje da se može javiti u bilo kojoj
fazi laktacije, pretežno u prvih 100 dana laktacije. Trajanje hemolaktije zavisi od
inteziteta kliničkog skora. Postoje brojni protokoli za kontrolu i skraćivanje trajanja
hemolaktije. Terapija hemolaktije zasniva se na primeni rastvora kalcijuma, vitamina
K, antikoagulansa, vazokonstriktora, vitamina C.
AB  - Haemolactia is clinical sign, that marks the presence of blood in milk. It leads
to the occurrence of economic losses due to the rejection of milk and therapy-affected
cows. The common reasons for the occurrence of haemolactia are trauma
udder, rupture blood vessels, haemorrhage due to diapedesis, infectious disease
(leptospirosis), thrombocytopenia, diapedesis due to hyperemia after parturition,
deficiency vitamins. The pathophysiology of the process and the exact cause of
its occurrence have not been established. Hemolactia can occur at any stage of
lactation, with the biggest problem being the first days of lactation, when it usually
occurs. The presence of blood in milk impairs the quality of colostrum, which is 
important for newborn calves. The aim of this work was to indicate the occurrence
of haemolactia in dairy cows. Long-term follow-up of the occurrence of hemolactia
indicates that it can occur at any stage of lactation, predominantly in the first 100
days. The duration of haemolactia depends on the clinical score of haemolactia.
There are numerous protocols for controlling and shortening the duration of haemolactia.
Therapy of haemolactia is based on the administration of calcium solutions,
vitamin K, anticoagulants, vasoconstrictors, vitamin C.
PB  - Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila
C3  - 14. Научни симпозијум репродукција животиња
T1  - Hemolaktija kod mlečnih krava
T1  - Haemolactia in dairy cows
EP  - 176
SP  - 175
ER  - 

@conference{
author = "Ninković, Milan and Zdravković, Nemanja and Jezdimirović, Nemanja and Žutić, Jadranka and Bojkovski, Jovan and Arsić, Sveta",
year = "2023",
abstract = "Hemolaktija je klinički znak, koji označava prisustvo krvi u mleku. Dovodi do
pojave ekonomskih gubitaka zbog odbacivanja mleka i terapije obolelih krava.
Uobičajeni razlozi za nastanak hemolaktije su trauma vimena, ruptura krvnih sudova,
krvarenje usled dijapedeze, infektivna bolest (leptospiroza), trombocitopenija,
dijapedeza usled hiperemije posle porođaja, deficit vitamina. Patofiziologija
procesa i tačan uzrok njegovog nastanka nisu utvrđeni. Hemolaktija se može javiti
u bilo kojoj fazi laktacije, a najveći problem javljaju u prvim danima laktacije.
Prisustvo krvi u mleku narušava kvalitet kolostruma, što je od značaja za novorođenu
telad. Cilj ovog rada bio je da ukaže na pojavu hemolaktije kod mlečnih krava.
Dugotrajno praćenje pojave hemolaktije ukazuje da se može javiti u bilo kojoj
fazi laktacije, pretežno u prvih 100 dana laktacije. Trajanje hemolaktije zavisi od
inteziteta kliničkog skora. Postoje brojni protokoli za kontrolu i skraćivanje trajanja
hemolaktije. Terapija hemolaktije zasniva se na primeni rastvora kalcijuma, vitamina
K, antikoagulansa, vazokonstriktora, vitamina C., Haemolactia is clinical sign, that marks the presence of blood in milk. It leads
to the occurrence of economic losses due to the rejection of milk and therapy-affected
cows. The common reasons for the occurrence of haemolactia are trauma
udder, rupture blood vessels, haemorrhage due to diapedesis, infectious disease
(leptospirosis), thrombocytopenia, diapedesis due to hyperemia after parturition,
deficiency vitamins. The pathophysiology of the process and the exact cause of
its occurrence have not been established. Hemolactia can occur at any stage of
lactation, with the biggest problem being the first days of lactation, when it usually
occurs. The presence of blood in milk impairs the quality of colostrum, which is 
important for newborn calves. The aim of this work was to indicate the occurrence
of haemolactia in dairy cows. Long-term follow-up of the occurrence of hemolactia
indicates that it can occur at any stage of lactation, predominantly in the first 100
days. The duration of haemolactia depends on the clinical score of haemolactia.
There are numerous protocols for controlling and shortening the duration of haemolactia.
Therapy of haemolactia is based on the administration of calcium solutions,
vitamin K, anticoagulants, vasoconstrictors, vitamin C.",
publisher = "Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila",
journal = "14. Научни симпозијум репродукција животиња",
title = "Hemolaktija kod mlečnih krava, Haemolactia in dairy cows",
pages = "176-175"
}

Ninković, M., Zdravković, N., Jezdimirović, N., Žutić, J., Bojkovski, J.,& Arsić, S.. (2023). Hemolaktija kod mlečnih krava. in 14. Научни симпозијум репродукција животиња
Beograd : Fakultet veterinarske medicine, Centar za izdavačku delatnost i promet učila., 175-176.

Ninković M, Zdravković N, Jezdimirović N, Žutić J, Bojkovski J, Arsić S. Hemolaktija kod mlečnih krava. in 14. Научни симпозијум репродукција животиња. 2023;:175-176..

Ninković, Milan, Zdravković, Nemanja, Jezdimirović, Nemanja, Žutić, Jadranka, Bojkovski, Jovan, Arsić, Sveta, "Hemolaktija kod mlečnih krava" in 14. Научни симпозијум репродукција животиња (2023):175-176.

TY  - CONF
AU  - Milovanović, Bojan
AU  - Stanojević, Slobodan
AU  - Kureljušić, Branislav
AU  - Zurovac Sapundžić, Zorana
AU  - Milićević, Vesna
AU  - Zdravković, Nemanja
AU  - Jezdimirović, Nemanja
AU  - Maletić, Milan
AU  - Savić, Božidar
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/816
AB  - Pojava povremenih pobačaja ne predstavlja razlog za zabrinutost. Dva glavna
kriterijuma kada pojava pobačaja postaje problem u zapatu su: ako stopa
pobačaja pređe 3% na 100 steonih krava ili 5% na 100 jagnjenih ovaca, ili
ukoliko veći broj životinja pobaci u kratkom vremenskom intervalu. U bilo koja
dva navedena slučaja neophodno je obavestiti ordinirajućeg veterinara i nadležnog
veterinarskog inspektora. Pobačaji se mogu podeliti na infektivne i neinfektivne.
Pobačaje infektivne prirode uzrokuju različiti virusi, bakterije (Brucella
abortus, Brucella ovis, Chlamydia abortus), gljivice, protozoe (Neospora
caninum) i rikecije (Coxiella burnetii). Uzročnici neinfektivne prirode mogu
biti: otrovne biljke, metabolički i hormonalni poremećaji, nutritivni deficiti,
traume i kongenitalne anomalije ploda. Etiološka dijagnoza pobačaja postavlja
se u svega 30% slučajeva – kod 40 do 50% slučajeva nije moguće utvrditi
uzrok. Podaci o zastupljenosti infektivnih agenasa kao uzročnika pobačaja variraju
u zavisnosti od regiona, načina držanja i uzoraka koji se dostavljaju na
laboratorijsko ispitivanje. Pored direktnog uticaja na zdravlje i dobrobit životinja,
pobačaji dovode i do ekonomskih gubitaka. Pojedini infektivni uzročnici
imaju zoonotski potencijal i predstavljaju opasnost po javno zdravlje. Zbog toga
prevencija pobačaja predstavlja imperativ u procesu proizvodnje.
AB  - The occurrence of periodical abortions is not a reason for concern. Two main
criteria when the abortions represent a problem on farm are: abortion rate
exceeds 3% per 100 pregnant cows or 5% per 100 pregnant ewes; certain
number of animals abort in a short time interval (abortion storm). In many of
two mentioned cases, it is necessary to inform the ordinating veterinarian and
the regional veterinary inspector. Etiology of abortions can be divided into
infectious and noninfectious. Infectious causes of abortions are viruses, bacteria
(Brucella abortus, Brucella ovis, Chlamydia abortus), fungi, protozoan (Neospora
caninum), rickettsias (Coxiella burnetii). Noninfectious abortions can be
caused by: heat stress, poisonous plants, metabolic and hormonal disorders,
nutritional deficits, trauma and congenital anomalies of fetus. The etiological
diagnosis of abortions is determinated in 30% of cases. In 40 to 50% of cases,
depending on the available laboratory diagnostics, it is not possible to establish
the cause. Data about prevalence of infectious agents vary depending on the
region, management and the samples that were submitted to diagnostic laboratory.
A spite of direct influence on animal health and welfare, abortions lead
to economic losses. Some infectious agents have zoonotic potential and represent
a risk to public health. Therefore, abortion control represent imperative in
the production process.
PB  - Beograd : Fakultet veterinarske medicine
C3  - Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023
T1  - Infektivni pobačaji preživara – zdravstveni i ekonomski značaj
T1  - Infectious abortions in ruminants–health and economic impact
EP  - 215
SP  - 207
ER  - 

@conference{
author = "Milovanović, Bojan and Stanojević, Slobodan and Kureljušić, Branislav and Zurovac Sapundžić, Zorana and Milićević, Vesna and Zdravković, Nemanja and Jezdimirović, Nemanja and Maletić, Milan and Savić, Božidar",
year = "2023",
abstract = "Pojava povremenih pobačaja ne predstavlja razlog za zabrinutost. Dva glavna
kriterijuma kada pojava pobačaja postaje problem u zapatu su: ako stopa
pobačaja pređe 3% na 100 steonih krava ili 5% na 100 jagnjenih ovaca, ili
ukoliko veći broj životinja pobaci u kratkom vremenskom intervalu. U bilo koja
dva navedena slučaja neophodno je obavestiti ordinirajućeg veterinara i nadležnog
veterinarskog inspektora. Pobačaji se mogu podeliti na infektivne i neinfektivne.
Pobačaje infektivne prirode uzrokuju različiti virusi, bakterije (Brucella
abortus, Brucella ovis, Chlamydia abortus), gljivice, protozoe (Neospora
caninum) i rikecije (Coxiella burnetii). Uzročnici neinfektivne prirode mogu
biti: otrovne biljke, metabolički i hormonalni poremećaji, nutritivni deficiti,
traume i kongenitalne anomalije ploda. Etiološka dijagnoza pobačaja postavlja
se u svega 30% slučajeva – kod 40 do 50% slučajeva nije moguće utvrditi
uzrok. Podaci o zastupljenosti infektivnih agenasa kao uzročnika pobačaja variraju
u zavisnosti od regiona, načina držanja i uzoraka koji se dostavljaju na
laboratorijsko ispitivanje. Pored direktnog uticaja na zdravlje i dobrobit životinja,
pobačaji dovode i do ekonomskih gubitaka. Pojedini infektivni uzročnici
imaju zoonotski potencijal i predstavljaju opasnost po javno zdravlje. Zbog toga
prevencija pobačaja predstavlja imperativ u procesu proizvodnje., The occurrence of periodical abortions is not a reason for concern. Two main
criteria when the abortions represent a problem on farm are: abortion rate
exceeds 3% per 100 pregnant cows or 5% per 100 pregnant ewes; certain
number of animals abort in a short time interval (abortion storm). In many of
two mentioned cases, it is necessary to inform the ordinating veterinarian and
the regional veterinary inspector. Etiology of abortions can be divided into
infectious and noninfectious. Infectious causes of abortions are viruses, bacteria
(Brucella abortus, Brucella ovis, Chlamydia abortus), fungi, protozoan (Neospora
caninum), rickettsias (Coxiella burnetii). Noninfectious abortions can be
caused by: heat stress, poisonous plants, metabolic and hormonal disorders,
nutritional deficits, trauma and congenital anomalies of fetus. The etiological
diagnosis of abortions is determinated in 30% of cases. In 40 to 50% of cases,
depending on the available laboratory diagnostics, it is not possible to establish
the cause. Data about prevalence of infectious agents vary depending on the
region, management and the samples that were submitted to diagnostic laboratory.
A spite of direct influence on animal health and welfare, abortions lead
to economic losses. Some infectious agents have zoonotic potential and represent
a risk to public health. Therefore, abortion control represent imperative in
the production process.",
publisher = "Beograd : Fakultet veterinarske medicine",
journal = "Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023",
title = "Infektivni pobačaji preživara – zdravstveni i ekonomski značaj, Infectious abortions in ruminants–health and economic impact",
pages = "215-207"
}

Milovanović, B., Stanojević, S., Kureljušić, B., Zurovac Sapundžić, Z., Milićević, V., Zdravković, N., Jezdimirović, N., Maletić, M.,& Savić, B.. (2023). Infektivni pobačaji preživara – zdravstveni i ekonomski značaj. in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023
Beograd : Fakultet veterinarske medicine., 207-215.

Milovanović B, Stanojević S, Kureljušić B, Zurovac Sapundžić Z, Milićević V, Zdravković N, Jezdimirović N, Maletić M, Savić B. Infektivni pobačaji preživara – zdravstveni i ekonomski značaj. in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023. 2023;:207-215..

Milovanović, Bojan, Stanojević, Slobodan, Kureljušić, Branislav, Zurovac Sapundžić, Zorana, Milićević, Vesna, Zdravković, Nemanja, Jezdimirović, Nemanja, Maletić, Milan, Savić, Božidar, "Infektivni pobačaji preživara – zdravstveni i ekonomski značaj" in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023 (2023):207-215.

TY  - CONF
AU  - Savić, Božidar
AU  - Kureljušić, Branislav
AU  - Milićević, Vesna
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Zdravković, Nemanja
AU  - Stevančević, Dimitrije
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/802
AB  - Porcine reproductive and respiratory syndrome virus CPRRSV) is the causative agent of a devastating pig disease worldwide, which is endemic in many countries, including the Serbia. Only limited epidemiological or molecular studies has been published on circulating PRRS-viruses in the Serbia since the early nineties. Therefore, the aim of this study is to investigate the genetic diversity of circulating PRRS-viruses in Serbia in the last ten years, by comparing the nucleotid€ sequences obtained for ORF5, wlth the ORF5 sequences of PRRSV 1 subtype 1.
PB  - ECPHM
C3  - Proceedings : ESPHM : 14th European symposium of porcine health management
T1  - Genetic diversity of the orf5 gene of type 1 porcine reproductive and respiratory syndrome virus isolates in Serbian swine herds from 2012 to 2022
EP  - 323
SP  - 323
ER  - 

@conference{
author = "Savić, Božidar and Kureljušić, Branislav and Milićević, Vesna and Jezdimirović, Nemanja and Milovanović, Bojan and Zdravković, Nemanja and Stevančević, Dimitrije",
year = "2023",
abstract = "Porcine reproductive and respiratory syndrome virus CPRRSV) is the causative agent of a devastating pig disease worldwide, which is endemic in many countries, including the Serbia. Only limited epidemiological or molecular studies has been published on circulating PRRS-viruses in the Serbia since the early nineties. Therefore, the aim of this study is to investigate the genetic diversity of circulating PRRS-viruses in Serbia in the last ten years, by comparing the nucleotid€ sequences obtained for ORF5, wlth the ORF5 sequences of PRRSV 1 subtype 1.",
publisher = "ECPHM",
journal = "Proceedings : ESPHM : 14th European symposium of porcine health management",
title = "Genetic diversity of the orf5 gene of type 1 porcine reproductive and respiratory syndrome virus isolates in Serbian swine herds from 2012 to 2022",
pages = "323-323"
}

Savić, B., Kureljušić, B., Milićević, V., Jezdimirović, N., Milovanović, B., Zdravković, N.,& Stevančević, D.. (2023). Genetic diversity of the orf5 gene of type 1 porcine reproductive and respiratory syndrome virus isolates in Serbian swine herds from 2012 to 2022. in Proceedings : ESPHM : 14th European symposium of porcine health management
ECPHM., 323-323.

Savić B, Kureljušić B, Milićević V, Jezdimirović N, Milovanović B, Zdravković N, Stevančević D. Genetic diversity of the orf5 gene of type 1 porcine reproductive and respiratory syndrome virus isolates in Serbian swine herds from 2012 to 2022. in Proceedings : ESPHM : 14th European symposium of porcine health management. 2023;:323-323..

Savić, Božidar, Kureljušić, Branislav, Milićević, Vesna, Jezdimirović, Nemanja, Milovanović, Bojan, Zdravković, Nemanja, Stevančević, Dimitrije, "Genetic diversity of the orf5 gene of type 1 porcine reproductive and respiratory syndrome virus isolates in Serbian swine herds from 2012 to 2022" in Proceedings : ESPHM : 14th European symposium of porcine health management (2023):323-323.

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Milićević, Vesna
AU  - Milovanović, Bojan
AU  - Glišić, Dimitrije
AU  - Maletić, Jelena
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Jasna
AU  - Prodanov Radulović, Jasna
AU  - Savić, Božidar
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/804
AB  - Biosecurity ls of paramount Importance to prevent the introduction and spread of pathogens in pig farms. Applied biosecurity measures and efficient on-farm management protect pigs from different infectious diseases. African swine fever CASF) is a severe, viral disease of domestic pigs and wild boar. After the occurrence in 2007 in Georgia, the disease gradually spread throughout Europe. The first case of ASF in Serbia was confirmed on July 30, 2019.
PB  - ECPHM
C3  - Proceedings : ESPHM : 14th European symposium of porcine health management
T1  - Assessment of biosecurity measures in the Serbian backyards where the first African swine fever cases were confirmed
EP  - 253
SP  - 253
ER  - 

@conference{
author = "Kureljušić, Branislav and Milićević, Vesna and Milovanović, Bojan and Glišić, Dimitrije and Maletić, Jelena and Jezdimirović, Nemanja and Kureljušić, Jasna and Prodanov Radulović, Jasna and Savić, Božidar",
year = "2023",
abstract = "Biosecurity ls of paramount Importance to prevent the introduction and spread of pathogens in pig farms. Applied biosecurity measures and efficient on-farm management protect pigs from different infectious diseases. African swine fever CASF) is a severe, viral disease of domestic pigs and wild boar. After the occurrence in 2007 in Georgia, the disease gradually spread throughout Europe. The first case of ASF in Serbia was confirmed on July 30, 2019.",
publisher = "ECPHM",
journal = "Proceedings : ESPHM : 14th European symposium of porcine health management",
title = "Assessment of biosecurity measures in the Serbian backyards where the first African swine fever cases were confirmed",
pages = "253-253"
}

Kureljušić, B., Milićević, V., Milovanović, B., Glišić, D., Maletić, J., Jezdimirović, N., Kureljušić, J., Prodanov Radulović, J.,& Savić, B.. (2023). Assessment of biosecurity measures in the Serbian backyards where the first African swine fever cases were confirmed. in Proceedings : ESPHM : 14th European symposium of porcine health management
ECPHM., 253-253.

Kureljušić B, Milićević V, Milovanović B, Glišić D, Maletić J, Jezdimirović N, Kureljušić J, Prodanov Radulović J, Savić B. Assessment of biosecurity measures in the Serbian backyards where the first African swine fever cases were confirmed. in Proceedings : ESPHM : 14th European symposium of porcine health management. 2023;:253-253..

Kureljušić, Branislav, Milićević, Vesna, Milovanović, Bojan, Glišić, Dimitrije, Maletić, Jelena, Jezdimirović, Nemanja, Kureljušić, Jasna, Prodanov Radulović, Jasna, Savić, Božidar, "Assessment of biosecurity measures in the Serbian backyards where the first African swine fever cases were confirmed" in Proceedings : ESPHM : 14th European symposium of porcine health management (2023):253-253.

TY  - JOUR
AU  - Milićević, Vesna
AU  - Glišić, Dimitrije
AU  - Zurovac Sapundžić, Zorana
AU  - Milovanović, Bojan
AU  - Maletić, Jelena
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Branislav
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/773
AB  - Contrary to pig farming in developedWestern countries, in a large part of the world, pigs
are still traditionally kept in small backyard farms, usually for family needs. Their main characteristics
are low biosecurity, swill feeding, natural breeding and uncontrolled trade. Given the high number
of backyard farms in Serbia and the risk they are thought to pose to intensive pig farming, the main
aim of this study was to evaluate the prevalence of major viral diseases of swine among traditionally
kept pigs in small holdings with low biosecurity. For this investigation, 222 serum samples from
69 backyard holdings were randomly selected and tested for antibodies to Porcine Reproductive and
Respiratory Syndrome virus (PRRSV), Aujeszky’s disease virus (ADV), Porcine Parvovirus (PPV)
and Swine influenza Virus (SIV) by enzyme-linked immunosorbent assay (ELISA). The herd-level
seroprevalence of PRRS, Aujeszky’s disease and PPV was 2.9%, 27.5% and 37.7%, respectively. Swine
influenza seroconversion was not confirmed in any of the tested holdings. Despite widely distributed
PPV and AD in backyard farms in Serbia, almost 50% of them are still negative for all the tested
diseases. The backyard farms must be monitored, and owners must be educated as their role in
eradication programs and obtaining country-free status may be crucial.
PB  - MDPI
T2  - Animals
T1  - Seroprevalence of viral enzootic diseases in swine backyard farms in Serbia
SP  - 3409
VL  - 13
DO  - 10.3390/ ani13213409
ER  - 

@article{
author = "Milićević, Vesna and Glišić, Dimitrije and Zurovac Sapundžić, Zorana and Milovanović, Bojan and Maletić, Jelena and Jezdimirović, Nemanja and Kureljušić, Branislav",
year = "2023",
abstract = "Contrary to pig farming in developedWestern countries, in a large part of the world, pigs
are still traditionally kept in small backyard farms, usually for family needs. Their main characteristics
are low biosecurity, swill feeding, natural breeding and uncontrolled trade. Given the high number
of backyard farms in Serbia and the risk they are thought to pose to intensive pig farming, the main
aim of this study was to evaluate the prevalence of major viral diseases of swine among traditionally
kept pigs in small holdings with low biosecurity. For this investigation, 222 serum samples from
69 backyard holdings were randomly selected and tested for antibodies to Porcine Reproductive and
Respiratory Syndrome virus (PRRSV), Aujeszky’s disease virus (ADV), Porcine Parvovirus (PPV)
and Swine influenza Virus (SIV) by enzyme-linked immunosorbent assay (ELISA). The herd-level
seroprevalence of PRRS, Aujeszky’s disease and PPV was 2.9%, 27.5% and 37.7%, respectively. Swine
influenza seroconversion was not confirmed in any of the tested holdings. Despite widely distributed
PPV and AD in backyard farms in Serbia, almost 50% of them are still negative for all the tested
diseases. The backyard farms must be monitored, and owners must be educated as their role in
eradication programs and obtaining country-free status may be crucial.",
publisher = "MDPI",
journal = "Animals",
title = "Seroprevalence of viral enzootic diseases in swine backyard farms in Serbia",
pages = "3409",
volume = "13",
doi = "10.3390/ ani13213409"
}

Milićević, V., Glišić, D., Zurovac Sapundžić, Z., Milovanović, B., Maletić, J., Jezdimirović, N.,& Kureljušić, B.. (2023). Seroprevalence of viral enzootic diseases in swine backyard farms in Serbia. in Animals
MDPI., 13, 3409.
https://doi.org/10.3390/ ani13213409

Milićević V, Glišić D, Zurovac Sapundžić Z, Milovanović B, Maletić J, Jezdimirović N, Kureljušić B. Seroprevalence of viral enzootic diseases in swine backyard farms in Serbia. in Animals. 2023;13:3409.
doi:10.3390/ ani13213409 .

Milićević, Vesna, Glišić, Dimitrije, Zurovac Sapundžić, Zorana, Milovanović, Bojan, Maletić, Jelena, Jezdimirović, Nemanja, Kureljušić, Branislav, "Seroprevalence of viral enzootic diseases in swine backyard farms in Serbia" in Animals, 13 (2023):3409,
https://doi.org/10.3390/ ani13213409 . .

TY  - CONF
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Branislav
AU  - Savić, Božidar
AU  - Milovanović, Bojan
AU  - Glišić, Dimitrije
AU  - Maksimović Zorić, Jelena
AU  - Milićević, Vesna
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/767
AB  - Kliničko oboljenje uzrokovano sa porcine citomegalovirus (PCMV) se javlja samo
kod svinja, iako se infekcije srodnim virusima pojavljuju i kod drugih životinjskih vrsta
uključujući i ljude. Citomegalovirus kod svinja uzrokuje rinitis sa inkluzionim
telašcima (IBR), PCMV pripada podfamiliji Betaherpesvirinae i familiji Herpesviridae,
ali nije svrstan ni u jedan rod, a genetska istraživanja su pokazala da je PCMV genetski
srodniji humanim herpes virusima 6 i 7. Infekcija sa PCMV je prisutna širom sveta,
dominantno u zemljama sa intenzivnom proizvodnjom svinja i uglavnom je klinički
inaparentna zbog stečenog imuniteta zapata. Virus se prenosi horizontalno
(oronazalnim putem), a moguća je i kongenitalna transmisija, pa inficirani fetusi mogu
biti, mumificirani, mrtvorođeni ili rođeni živi kao slabo vitalna prasad. Kliničko
oboljenje se pojavljuje u akutnoj ili subakutnoj formi kod prasadi starosti do 4 nedelje,
a može se pojaviti i kod drugih starosnih kategorija u neimunim zapatima. Svinje koje
su prebolele infekciju ostaju doživotne kliconoše. Suide predstavljaju jedini rezervoar
virusa u prirodi. Rinitis sa inkluzionim telašcima je visoko prevalentna infekcija i
pretpostavlja se da je prevalencija oboljenja preko 90% na globalnom nivou, odnosno
98% u Evropi. U našoj zemlji još uvek nisu rađena opsežna istraživanja na utvrđivanju
prevalence oboljenja zbog čega su prevalenca infekcije i incidenca oboljenja još uvek
nepoznate. Zbog cirkulacije drugih respiratornih virusa u farmskim uslovima uzgoja
svinja, PCMV je često zapostavljen. Na poziv veterinarske službe, na farmi koja je imala učestale probleme sa
respiratornim oboljenjima, izvršili smo uzorkovanje oralnog fluida i analizirali
prikupljene uzorke primenom lančane reakcije polimeraze na prisustvo sledećih
virusnih agenasa: Encephalomyocarditis virus (EMCV), PCMV, Porcine circovirus tip 2
(PCV2). Virus reproduktivnog i respiratornog sindroma svinja (PRRSV) i Virus
influence svinja (SIV), sa ciljem uvida u prisustvo virusnih infektivnih agenasa na
farmi. Izvršenim analizama smo pored detekcije PRRSV, PCV2 i SIV, ustanovili i
prisustvo genoma PCMV kod prasadi iz odgoja. Mortalitet prasadi u neimunim
zapatima od posledica kliničkog PCMV-rinitisa može dostići 10%, ali se može povećati
do čak 50% ukoliko se bolest komplikuje drugim virusnim ili bakterijskim infekcijama.
Klinički značaj prisustva PCMV u konkretnom slučaju bi trebalo razmatrati u
kontekstu detekcije drugih virusnih patogena i njihovog sinergističkog efekta.
Međutim, obzirom da PCMV samostalno ili u koinfekcijama sa drugim, pre svega
virusnim respiratornim agensima može biti uzrok povećanja mortaliteta, ne treba ga
zanemariti. Vakcina protiv PCMV i specifična terapija ovog oboljenja ne postoje, sa
druge strane, ne postojanje informacija o prevalenci PCMV u našoj zemlji kao ni
vršenje rutinskog pregleda na ovu infekciju, predstavlja značajan rizik za širenje
virusa pre svega uvođenjem novonabavljenih životinja u zapat.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 34. Savetovanje veterinara Srbije, Zlatibor,  7-10. septembar 2023
T1  - Prva molekularna detekcija citomegalovirusa svinja u Srbiji
EP  - 95
SP  - 90
ER  - 

@conference{
author = "Jezdimirović, Nemanja and Kureljušić, Branislav and Savić, Božidar and Milovanović, Bojan and Glišić, Dimitrije and Maksimović Zorić, Jelena and Milićević, Vesna",
year = "2023",
abstract = "Kliničko oboljenje uzrokovano sa porcine citomegalovirus (PCMV) se javlja samo
kod svinja, iako se infekcije srodnim virusima pojavljuju i kod drugih životinjskih vrsta
uključujući i ljude. Citomegalovirus kod svinja uzrokuje rinitis sa inkluzionim
telašcima (IBR), PCMV pripada podfamiliji Betaherpesvirinae i familiji Herpesviridae,
ali nije svrstan ni u jedan rod, a genetska istraživanja su pokazala da je PCMV genetski
srodniji humanim herpes virusima 6 i 7. Infekcija sa PCMV je prisutna širom sveta,
dominantno u zemljama sa intenzivnom proizvodnjom svinja i uglavnom je klinički
inaparentna zbog stečenog imuniteta zapata. Virus se prenosi horizontalno
(oronazalnim putem), a moguća je i kongenitalna transmisija, pa inficirani fetusi mogu
biti, mumificirani, mrtvorođeni ili rođeni živi kao slabo vitalna prasad. Kliničko
oboljenje se pojavljuje u akutnoj ili subakutnoj formi kod prasadi starosti do 4 nedelje,
a može se pojaviti i kod drugih starosnih kategorija u neimunim zapatima. Svinje koje
su prebolele infekciju ostaju doživotne kliconoše. Suide predstavljaju jedini rezervoar
virusa u prirodi. Rinitis sa inkluzionim telašcima je visoko prevalentna infekcija i
pretpostavlja se da je prevalencija oboljenja preko 90% na globalnom nivou, odnosno
98% u Evropi. U našoj zemlji još uvek nisu rađena opsežna istraživanja na utvrđivanju
prevalence oboljenja zbog čega su prevalenca infekcije i incidenca oboljenja još uvek
nepoznate. Zbog cirkulacije drugih respiratornih virusa u farmskim uslovima uzgoja
svinja, PCMV je često zapostavljen. Na poziv veterinarske službe, na farmi koja je imala učestale probleme sa
respiratornim oboljenjima, izvršili smo uzorkovanje oralnog fluida i analizirali
prikupljene uzorke primenom lančane reakcije polimeraze na prisustvo sledećih
virusnih agenasa: Encephalomyocarditis virus (EMCV), PCMV, Porcine circovirus tip 2
(PCV2). Virus reproduktivnog i respiratornog sindroma svinja (PRRSV) i Virus
influence svinja (SIV), sa ciljem uvida u prisustvo virusnih infektivnih agenasa na
farmi. Izvršenim analizama smo pored detekcije PRRSV, PCV2 i SIV, ustanovili i
prisustvo genoma PCMV kod prasadi iz odgoja. Mortalitet prasadi u neimunim
zapatima od posledica kliničkog PCMV-rinitisa može dostići 10%, ali se može povećati
do čak 50% ukoliko se bolest komplikuje drugim virusnim ili bakterijskim infekcijama.
Klinički značaj prisustva PCMV u konkretnom slučaju bi trebalo razmatrati u
kontekstu detekcije drugih virusnih patogena i njihovog sinergističkog efekta.
Međutim, obzirom da PCMV samostalno ili u koinfekcijama sa drugim, pre svega
virusnim respiratornim agensima može biti uzrok povećanja mortaliteta, ne treba ga
zanemariti. Vakcina protiv PCMV i specifična terapija ovog oboljenja ne postoje, sa
druge strane, ne postojanje informacija o prevalenci PCMV u našoj zemlji kao ni
vršenje rutinskog pregleda na ovu infekciju, predstavlja značajan rizik za širenje
virusa pre svega uvođenjem novonabavljenih životinja u zapat.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "34. Savetovanje veterinara Srbije, Zlatibor,  7-10. septembar 2023",
title = "Prva molekularna detekcija citomegalovirusa svinja u Srbiji",
pages = "95-90"
}

Jezdimirović, N., Kureljušić, B., Savić, B., Milovanović, B., Glišić, D., Maksimović Zorić, J.,& Milićević, V.. (2023). Prva molekularna detekcija citomegalovirusa svinja u Srbiji. in 34. Savetovanje veterinara Srbije, Zlatibor,  7-10. septembar 2023
Beograd : Srpsko veterinarsko društvo., 90-95.

Jezdimirović N, Kureljušić B, Savić B, Milovanović B, Glišić D, Maksimović Zorić J, Milićević V. Prva molekularna detekcija citomegalovirusa svinja u Srbiji. in 34. Savetovanje veterinara Srbije, Zlatibor,  7-10. septembar 2023. 2023;:90-95..

Jezdimirović, Nemanja, Kureljušić, Branislav, Savić, Božidar, Milovanović, Bojan, Glišić, Dimitrije, Maksimović Zorić, Jelena, Milićević, Vesna, "Prva molekularna detekcija citomegalovirusa svinja u Srbiji" in 34. Savetovanje veterinara Srbije, Zlatibor,  7-10. septembar 2023 (2023):90-95.

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Savić, Božidar
AU  - Milovanović, Bojan
AU  - Maletić, Jelena
AU  - Ninković, Milan
AU  - Jezdimirović, Nemanja
AU  - Prodanov Radulović, Jasna
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/686
AB  - Biosecurity measures together with the efficient on-farm management embraces all aspects of
the prevention of pathogens entering pig farms, regardless of structure and animal number. In
the present study assessment of biosecurity measures in the commercial (industrial) pig farms in
Serbia was carried out through application of the questionnaire to farm veterinarians.
To assess biosecurity in commercial (industrial) farms, a Biocheck online survey
(https://biocheckgent.com) was conducted in the ten commercial pigs farms located in the
Northern part of Serbia where industrial pig production is localized and the highest density of pig
production can be found.
The results of the external biosecurity assessment showed a mean score of 75.55%, compared to
the average in Serbia, which was 68.55%, and the global average of 73%. External biosecurity
assessment showed the lowest scores for feed, water and equipment supply (47%). The
assessment of internal biosecurity revealed a score of 54.89% compared to the national average
of 44.22% and the world average of 64.11%. Regarding internal biosecurity, the lowest
percentage score (37.22%) was confirmed for farrowing and suckling period and for finishing unit
(37.67%). The overall biosecurity score for commercial pig farms included in this study was
65.55%. The national average was 56.33%, while the global average was 68.67%.
This study showed a bit less lower level of biosecurity measures in commercial pig farms in Serbia
comparing with global average. Certainly, having in mind the different pig production systems in
Serbia, there is urgent need to improve biosecurity in industrial farms. Serbia as a Western Balkan
country, has variable pig farming system characterized by a domination of traditional family
farms, smallholdings, backyard production and semi-free and free-range. Currently, traditional
farming methods in Serbia represent a cultural identity. The biosecurity measures that could be
implemented in extisted animal production systems need to be urgently identified.
PB  - Ghent : Faculty of veterinary medicine
C3  - COST action CA20103 "Biosecurity Enhanced Through Training Evaluation and Raising Awareness"
T1  - Assessment of biosecurity measures in the commercial (industrial) pig farms in Serbia
EP  - 39
SP  - 39
ER  - 

@conference{
author = "Kureljušić, Branislav and Savić, Božidar and Milovanović, Bojan and Maletić, Jelena and Ninković, Milan and Jezdimirović, Nemanja and Prodanov Radulović, Jasna",
year = "2023",
abstract = "Biosecurity measures together with the efficient on-farm management embraces all aspects of
the prevention of pathogens entering pig farms, regardless of structure and animal number. In
the present study assessment of biosecurity measures in the commercial (industrial) pig farms in
Serbia was carried out through application of the questionnaire to farm veterinarians.
To assess biosecurity in commercial (industrial) farms, a Biocheck online survey
(https://biocheckgent.com) was conducted in the ten commercial pigs farms located in the
Northern part of Serbia where industrial pig production is localized and the highest density of pig
production can be found.
The results of the external biosecurity assessment showed a mean score of 75.55%, compared to
the average in Serbia, which was 68.55%, and the global average of 73%. External biosecurity
assessment showed the lowest scores for feed, water and equipment supply (47%). The
assessment of internal biosecurity revealed a score of 54.89% compared to the national average
of 44.22% and the world average of 64.11%. Regarding internal biosecurity, the lowest
percentage score (37.22%) was confirmed for farrowing and suckling period and for finishing unit
(37.67%). The overall biosecurity score for commercial pig farms included in this study was
65.55%. The national average was 56.33%, while the global average was 68.67%.
This study showed a bit less lower level of biosecurity measures in commercial pig farms in Serbia
comparing with global average. Certainly, having in mind the different pig production systems in
Serbia, there is urgent need to improve biosecurity in industrial farms. Serbia as a Western Balkan
country, has variable pig farming system characterized by a domination of traditional family
farms, smallholdings, backyard production and semi-free and free-range. Currently, traditional
farming methods in Serbia represent a cultural identity. The biosecurity measures that could be
implemented in extisted animal production systems need to be urgently identified.",
publisher = "Ghent : Faculty of veterinary medicine",
journal = "COST action CA20103 "Biosecurity Enhanced Through Training Evaluation and Raising Awareness"",
title = "Assessment of biosecurity measures in the commercial (industrial) pig farms in Serbia",
pages = "39-39"
}

Kureljušić, B., Savić, B., Milovanović, B., Maletić, J., Ninković, M., Jezdimirović, N.,& Prodanov Radulović, J.. (2023). Assessment of biosecurity measures in the commercial (industrial) pig farms in Serbia. in COST action CA20103 "Biosecurity Enhanced Through Training Evaluation and Raising Awareness"
Ghent : Faculty of veterinary medicine., 39-39.

Kureljušić B, Savić B, Milovanović B, Maletić J, Ninković M, Jezdimirović N, Prodanov Radulović J. Assessment of biosecurity measures in the commercial (industrial) pig farms in Serbia. in COST action CA20103 "Biosecurity Enhanced Through Training Evaluation and Raising Awareness". 2023;:39-39..

Kureljušić, Branislav, Savić, Božidar, Milovanović, Bojan, Maletić, Jelena, Ninković, Milan, Jezdimirović, Nemanja, Prodanov Radulović, Jasna, "Assessment of biosecurity measures in the commercial (industrial) pig farms in Serbia" in COST action CA20103 "Biosecurity Enhanced Through Training Evaluation and Raising Awareness" (2023):39-39.

TY  - CONF
AU  - Maksimović Zorić, Jelena
AU  - Veljović, Ljubiša
AU  - Glišić, Dimitrije
AU  - Jezdimirović, Nemanja
AU  - Savić, Božidar
AU  - Milovanović, Bojan
AU  - Maletić, Jelena
AU  - Radosavljević, Vladimir
AU  - Kureljušić, Branislav
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/652
AB  - Swine influenza is a worldwide present respiratory disease of swine, in majority of cases caused by H1N1,
H1N2, and H3N2 subtypes of swine influenza A virus (swIAV). Exploration of the swIAV in Serbia in recent
ten years mainly was oriented to the passive surveillance and examination within PRDC on commercial pig
farms. The latest results suggest circulation of the viruses in the majority of the analysed commercial farms
and the presence of two subtypes - H1N1 and H3N2. Even though the problem exists none of the farms
apply vaccination as a measure of disease control. The aim of this research is to analyse the results of
passive surveillance on the two commercial farms conducted from 2020th to 2022nd.
A total of 94 samples for molecular analyses and 528 samples for serological analyses were submitted to
the Institute of Veterinary Medicine of Serbia during this period. These samples were obtained from swine
raised in two commercial farms (farm A and farm B) that practice farrow-to-finish production and have
implemented satisfactory biosecurity measures. The samples for molecular examination were mummified
fetuses, nasal swabs, oral fluids, parenchymatous organs, lungs, and sera. All samples were tested by M
gene real-time RT-PCR, according to the accredited WHO protocol (2009) for detection of influenza A
viruses. One virus was typed using multiplex real-time RT-PCR protocols described by Henritzi et al. (2016).
Serological examination was conducted using ELISA test (Ingezim Influenza A Kit, Ingenasa), and tested sera
originated from sows, suckling piglets, and nursing pigs.
During three year period influenza A viruses were detected on both farms, having on average 55,3% of the
analyzed samples positive. The highest detection rate was amongst the nasal swab (78.7%) and oral fluid
samples (83.3%), while virus was not confirmed in mummified fetuses and sera. Most of the samples
analyzed by PCR originated from farm A (80 samples), and the majority of tested were positive (60%).
Molecular typing revealed presence of H1N1 subtype in farm A that is in accordance with previous results
that confirmed H1N1 as dominating subtype that circulates in commercial farms in Serbia. Serology
examination confirmed a high overall seroprevalence of 64,6%. The serum samples from nursing pigs
accounted for the highest proportion (95.4%) among those examined, as respiratory issues linked to PRDC
typically manifest in this group. Given the endemic presence of swIAVs in the farms under analysis, there is
a pressing need to conduct further research on the circulating viruses and enhance the control measures
employed on these farms.
PB  - ESFLU
C3  - ESFLU Scientific meeting, Barcelona, 25-27th April 2023
T1  - Serological and molecular investigation of influenza in commercial pig farms in Serbia
ER  - 

@conference{
author = "Maksimović Zorić, Jelena and Veljović, Ljubiša and Glišić, Dimitrije and Jezdimirović, Nemanja and Savić, Božidar and Milovanović, Bojan and Maletić, Jelena and Radosavljević, Vladimir and Kureljušić, Branislav",
year = "2023",
abstract = "Swine influenza is a worldwide present respiratory disease of swine, in majority of cases caused by H1N1,
H1N2, and H3N2 subtypes of swine influenza A virus (swIAV). Exploration of the swIAV in Serbia in recent
ten years mainly was oriented to the passive surveillance and examination within PRDC on commercial pig
farms. The latest results suggest circulation of the viruses in the majority of the analysed commercial farms
and the presence of two subtypes - H1N1 and H3N2. Even though the problem exists none of the farms
apply vaccination as a measure of disease control. The aim of this research is to analyse the results of
passive surveillance on the two commercial farms conducted from 2020th to 2022nd.
A total of 94 samples for molecular analyses and 528 samples for serological analyses were submitted to
the Institute of Veterinary Medicine of Serbia during this period. These samples were obtained from swine
raised in two commercial farms (farm A and farm B) that practice farrow-to-finish production and have
implemented satisfactory biosecurity measures. The samples for molecular examination were mummified
fetuses, nasal swabs, oral fluids, parenchymatous organs, lungs, and sera. All samples were tested by M
gene real-time RT-PCR, according to the accredited WHO protocol (2009) for detection of influenza A
viruses. One virus was typed using multiplex real-time RT-PCR protocols described by Henritzi et al. (2016).
Serological examination was conducted using ELISA test (Ingezim Influenza A Kit, Ingenasa), and tested sera
originated from sows, suckling piglets, and nursing pigs.
During three year period influenza A viruses were detected on both farms, having on average 55,3% of the
analyzed samples positive. The highest detection rate was amongst the nasal swab (78.7%) and oral fluid
samples (83.3%), while virus was not confirmed in mummified fetuses and sera. Most of the samples
analyzed by PCR originated from farm A (80 samples), and the majority of tested were positive (60%).
Molecular typing revealed presence of H1N1 subtype in farm A that is in accordance with previous results
that confirmed H1N1 as dominating subtype that circulates in commercial farms in Serbia. Serology
examination confirmed a high overall seroprevalence of 64,6%. The serum samples from nursing pigs
accounted for the highest proportion (95.4%) among those examined, as respiratory issues linked to PRDC
typically manifest in this group. Given the endemic presence of swIAVs in the farms under analysis, there is
a pressing need to conduct further research on the circulating viruses and enhance the control measures
employed on these farms.",
publisher = "ESFLU",
journal = "ESFLU Scientific meeting, Barcelona, 25-27th April 2023",
title = "Serological and molecular investigation of influenza in commercial pig farms in Serbia"
}

Maksimović Zorić, J., Veljović, L., Glišić, D., Jezdimirović, N., Savić, B., Milovanović, B., Maletić, J., Radosavljević, V.,& Kureljušić, B.. (2023). Serological and molecular investigation of influenza in commercial pig farms in Serbia. in ESFLU Scientific meeting, Barcelona, 25-27th April 2023
ESFLU..

Maksimović Zorić J, Veljović L, Glišić D, Jezdimirović N, Savić B, Milovanović B, Maletić J, Radosavljević V, Kureljušić B. Serological and molecular investigation of influenza in commercial pig farms in Serbia. in ESFLU Scientific meeting, Barcelona, 25-27th April 2023. 2023;..

Maksimović Zorić, Jelena, Veljović, Ljubiša, Glišić, Dimitrije, Jezdimirović, Nemanja, Savić, Božidar, Milovanović, Bojan, Maletić, Jelena, Radosavljević, Vladimir, Kureljušić, Branislav, "Serological and molecular investigation of influenza in commercial pig farms in Serbia" in ESFLU Scientific meeting, Barcelona, 25-27th April 2023 (2023).

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Savić, Božidar
AU  - Milićević, Vesna
AU  - Radanović, Oliver
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Weissenbacher-Lang, Christiane
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/544
AB  - U etiopatogenezi nekroze ušne školjke kod svinja mogu biti uključeni
infektivni agensi kao i neinfektivni faktori. Griža ušiju kao oblik
kanibalizma obično predstavlja uzrok nekroze ušne školjke kod svinja, ali se
nekroza može pojaviti i bez ikakvih dokaza o postojanju griže ušiju. Iako su
istraživači ispitivali ulogu različitih uzročnika za razvoj lezija ušne
školjke, do sada nije potvrđena definitivna etiologija.
U ovom radu opisan je slučaj nekroze ušne školjke 10 uginulih svinja sa jedne
komercijalne farme svinja u Srbiji. Prema podacima ordinirajućeg veterinara
farme, lezije na ušnoj školjki su prvi put otkrivene kod svinja starosti između
45 i 50 dana kod više od 80% jedinki, u svim boksevima u odgajivalištu. Za
ispitivanje su uzete ušne školjke uginulih svinja i sprovedena su
patomorfološka, bakteriološka i molekularno-genetička ispitivanja.
Makroskopski, ustanovljene lezije su opisane kao blagi, superficijalni
dermatitis, a u težim slučajevima, bila je prisutna duboka inflamacija dermisa
sa ulceracijom i nekrozom. Histopatološkim pregledom utvrđen je erozivni i
ulcerozni dermatitis ušne školjke sa infiltracijom neutrofilnim granulocitima
i limfocitima, fibroplazija i bazofilne kolonije bakterija u krastama.
U osam uzoraka krasti i tkiva ušiju izolovani su S. aureus (MRSA soj), S. hyicus i
Streptococcus grupe C. U dva uzorka otkriven je samo S. hyicus. Svi uzorci bili su
pozitivni na T. denticola/T. putidum grupu i negativni na Mycoplasma suis. Sedam
od deset oralnih briseva bilo je pozitivno na T. denticola/T. putidum grupu. Dva
PCR proizvoda su sekvencionirana i filogenetska analiza je pokazala genetsku
sličnost sekvenci nukleotida sa T. medium/T. vincentii grupom i Treponema pedis.
Iako su bakterijski agensi uspešno utvrđeni u ispitanim uzorcima ušnih
školjki, neinfektivni faktori, uključujući dokazanu visoku vlažnost vazduha i
deficit sirovih proteina u obroku, takođe mogu biti uključeni u razvoj sindroma
nekroze ušne školjke. Istovremena detekcija treponema u uzorcima krasti i tkiva
ušiju i uzorcima brisa usne šupljine može ukazivati na prenos bakterija tokom
griže ušiju. Ovaj slučaj još jednom naglašava multifaktorijalni karakter ovog
sindroma što otežava kontrolu i prevenciju ove bolesti.
AB  - Infectious agents as well as non-infectious factors can be involved in the
etiopathogenesis of porcine ear necrosis. Furthermore, ear biting is commonly
suggested as a cause of ear necrosis in pigs, but it may also appear without any
evidence of ear biting. Although many causative agents for the development of ear
lesions have been suggested by investigators no definitive aetiology has been
identified so far.
This report describes case of ear necrosis of 10 dead pigs from one commercial pig
farm in Serbia. According to to the data obtained by the farm veterinarian, ear lesions
were first detected in pigs between 45 and 50 days of age from all pens and more than
80% of the pig population was affected. Auriculae of dead pigs were sampled and
pathomorphological, bacteriological and molecular-genetic examinations were carried
out.
The lesions ranged from mild, superficial dermatitis to severe, deep inflammation with
exudation, ulceration and necrosis. Histopathological examination revealed erosive
and ulcerative dermatitis of the pinna with neutrophilic and lymphocytic infiltration,
fibroplasia and bacterial colonies in the crusts.
In eight ear tissue scraping samples, S. aureus (MRSA strain), S. hyicus and
Streptococcus group C were isolated. In two samples only S. hyicus was detected. All
ear tissue scraping samples tested positive for the T. denticola/T. putidum group and
negative for Mycoplasma suis. Seven out of ten oral swabs were positive for the T.
denticola/T. putidum group. Two of the PCR products were sequenced, and the
phylogenetic analysis showed a genetic relationship of the treponeme nucleotide
sequences to the T. medium/T. vincentii group and Treponema pedis.
Although bacterial agents were determined successfully in ear tissue scraping
samples, non-infectious triggering factors including proven high humidity levels and
crude protein deficiencies may also have been involved in the development of ear
necrosis syndrome. The concurrent detection of Treponema in both ear tissue
scrapings and oral swab samples might indicate the transmission of the bacterium
during ear biting. The present case once again highlights the multifactorial character
of this condition that renders the control and prevention of this disease difficult.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani)
T1  - Nekroza ušne školjke kod svinja – ispitivanje moguće infektivne etiologije
T1  - Porcine ear necrosis – investigation of possible infectious etiology
EP  - 143
SP  - 142
ER  - 

@conference{
author = "Kureljušić, Branislav and Savić, Božidar and Milićević, Vesna and Radanović, Oliver and Jezdimirović, Nemanja and Milovanović, Bojan and Weissenbacher-Lang, Christiane",
year = "2023",
abstract = "U etiopatogenezi nekroze ušne školjke kod svinja mogu biti uključeni
infektivni agensi kao i neinfektivni faktori. Griža ušiju kao oblik
kanibalizma obično predstavlja uzrok nekroze ušne školjke kod svinja, ali se
nekroza može pojaviti i bez ikakvih dokaza o postojanju griže ušiju. Iako su
istraživači ispitivali ulogu različitih uzročnika za razvoj lezija ušne
školjke, do sada nije potvrđena definitivna etiologija.
U ovom radu opisan je slučaj nekroze ušne školjke 10 uginulih svinja sa jedne
komercijalne farme svinja u Srbiji. Prema podacima ordinirajućeg veterinara
farme, lezije na ušnoj školjki su prvi put otkrivene kod svinja starosti između
45 i 50 dana kod više od 80% jedinki, u svim boksevima u odgajivalištu. Za
ispitivanje su uzete ušne školjke uginulih svinja i sprovedena su
patomorfološka, bakteriološka i molekularno-genetička ispitivanja.
Makroskopski, ustanovljene lezije su opisane kao blagi, superficijalni
dermatitis, a u težim slučajevima, bila je prisutna duboka inflamacija dermisa
sa ulceracijom i nekrozom. Histopatološkim pregledom utvrđen je erozivni i
ulcerozni dermatitis ušne školjke sa infiltracijom neutrofilnim granulocitima
i limfocitima, fibroplazija i bazofilne kolonije bakterija u krastama.
U osam uzoraka krasti i tkiva ušiju izolovani su S. aureus (MRSA soj), S. hyicus i
Streptococcus grupe C. U dva uzorka otkriven je samo S. hyicus. Svi uzorci bili su
pozitivni na T. denticola/T. putidum grupu i negativni na Mycoplasma suis. Sedam
od deset oralnih briseva bilo je pozitivno na T. denticola/T. putidum grupu. Dva
PCR proizvoda su sekvencionirana i filogenetska analiza je pokazala genetsku
sličnost sekvenci nukleotida sa T. medium/T. vincentii grupom i Treponema pedis.
Iako su bakterijski agensi uspešno utvrđeni u ispitanim uzorcima ušnih
školjki, neinfektivni faktori, uključujući dokazanu visoku vlažnost vazduha i
deficit sirovih proteina u obroku, takođe mogu biti uključeni u razvoj sindroma
nekroze ušne školjke. Istovremena detekcija treponema u uzorcima krasti i tkiva
ušiju i uzorcima brisa usne šupljine može ukazivati na prenos bakterija tokom
griže ušiju. Ovaj slučaj još jednom naglašava multifaktorijalni karakter ovog
sindroma što otežava kontrolu i prevenciju ove bolesti., Infectious agents as well as non-infectious factors can be involved in the
etiopathogenesis of porcine ear necrosis. Furthermore, ear biting is commonly
suggested as a cause of ear necrosis in pigs, but it may also appear without any
evidence of ear biting. Although many causative agents for the development of ear
lesions have been suggested by investigators no definitive aetiology has been
identified so far.
This report describes case of ear necrosis of 10 dead pigs from one commercial pig
farm in Serbia. According to to the data obtained by the farm veterinarian, ear lesions
were first detected in pigs between 45 and 50 days of age from all pens and more than
80% of the pig population was affected. Auriculae of dead pigs were sampled and
pathomorphological, bacteriological and molecular-genetic examinations were carried
out.
The lesions ranged from mild, superficial dermatitis to severe, deep inflammation with
exudation, ulceration and necrosis. Histopathological examination revealed erosive
and ulcerative dermatitis of the pinna with neutrophilic and lymphocytic infiltration,
fibroplasia and bacterial colonies in the crusts.
In eight ear tissue scraping samples, S. aureus (MRSA strain), S. hyicus and
Streptococcus group C were isolated. In two samples only S. hyicus was detected. All
ear tissue scraping samples tested positive for the T. denticola/T. putidum group and
negative for Mycoplasma suis. Seven out of ten oral swabs were positive for the T.
denticola/T. putidum group. Two of the PCR products were sequenced, and the
phylogenetic analysis showed a genetic relationship of the treponeme nucleotide
sequences to the T. medium/T. vincentii group and Treponema pedis.
Although bacterial agents were determined successfully in ear tissue scraping
samples, non-infectious triggering factors including proven high humidity levels and
crude protein deficiencies may also have been involved in the development of ear
necrosis syndrome. The concurrent detection of Treponema in both ear tissue
scrapings and oral swab samples might indicate the transmission of the bacterium
during ear biting. The present case once again highlights the multifactorial character
of this condition that renders the control and prevention of this disease difficult.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani)",
title = "Nekroza ušne školjke kod svinja – ispitivanje moguće infektivne etiologije, Porcine ear necrosis – investigation of possible infectious etiology",
pages = "143-142"
}

Kureljušić, B., Savić, B., Milićević, V., Radanović, O., Jezdimirović, N., Milovanović, B.,& Weissenbacher-Lang, C.. (2023). Nekroza ušne školjke kod svinja – ispitivanje moguće infektivne etiologije. in XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani)
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 142-143.

Kureljušić B, Savić B, Milićević V, Radanović O, Jezdimirović N, Milovanović B, Weissenbacher-Lang C. Nekroza ušne školjke kod svinja – ispitivanje moguće infektivne etiologije. in XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani). 2023;:142-143..

Kureljušić, Branislav, Savić, Božidar, Milićević, Vesna, Radanović, Oliver, Jezdimirović, Nemanja, Milovanović, Bojan, Weissenbacher-Lang, Christiane, "Nekroza ušne školjke kod svinja – ispitivanje moguće infektivne etiologije" in XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani) (2023):142-143.

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Savić, Božidar
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Maksimović Zorić, Jelena
AU  - Dobrosavljević, Ivan
AU  - Prodanov Radulović, Jasna
AU  - Glišić, Dimitrije
AU  - Milićević, Vesna
AU  - Bojkovski, Jovan
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/499
AB  - Bolesti svinja koje se karakterišu pojavom vezikularnog sindroma su slinavka i šap,
vezikularna bolest svinja, vezikularni stomatitis, vezikularni egzantem svinja i Seneka bolest
svinja. Virus slinavke i šapa, virus vezikularne bolesti svinja i Senecavirus A pripadaju familiji
Picornaviridae.
Slinavka i šap je visoko kontagiozna virusna bolest različitih vrsta papkara koja se kod
svinja karakteriše apatijom, febrom, pojavom vezikula u predelu rila, usne šupljine, papaka i
mlečne žlezde. Klinička slika kod svinja uobičajeno nije teška, a u težim slučajevima može se
javiti eksungulacija. Vrata infekcije su sluznica ždrela i tonzile gde se odvija primarna replikacija
virusa, a potom sledi viremija sa sekundarnom replikacijom virusa na predilekcionim mestima.
Poznato je da inficirana svinja može da proizvede 400 miliona infektivnih doza dnevno i da tako
predstavlja značajan izvor infekcije za druge prijemčive vrste.
Infekcija Senecavirusom A se karakteriše povišenim mortalitetom kod prsadi na sisi do
sedmog dana starosti. Kod priplodnih kategorija svinja, postoji povišena telesna temperatura,
anoreksija, letargija, pojava vezikula na rilu, sluznici usne šupljine i koronarnom rubu papaka.
Pojava bolesti kod svinja koje se karakterišu vezikularnim sindromom uvek izaziva veliku
zabrinutost imajući u vidu da je klinički nemoguće razlikovati lezije koje izaziva virus slinavke i
šapa i drugi virusi. Konačnu dijagnozu je moguće jedino potvrditi u laboratoriji. Obzirom da su
svinje prijemčive za više vrsta virusa koji dovode do vezikularnog sindroma kao i činjenicu da
svinje pozitivne na slinavku i šap izlučuju veliku količinu virusa u spoljašnju sredinu putem
aerosola, blagovremeno utvrđivanje dijagnoze je od prvorazrednog značaja.
Ukoliko postoji sumnja na neku od bolesti koje se karakterišu vezikularnim sindromom
potrebno je bez odlaganja obavestiti nadležnog veterinarskog inspektora i regionalni institut koji
zajedno sa terenskom veterinarskom službom utvrđuju dalji postupak u skladu sa zakonskom
regulativom i sprovode epizootiološki nadzor i uzorkovanje materijala za laboratorijska
ispitivanja. Uzorci prvog prioriteta su pokrovni epitel vezikula, sadržaj vezikula, oralni/nazalni brisevi i uzorci krvi. Laboratorijska dijagnostika omogućava dobijanje rezultata u roku od
nekoliko časova.
PB  - Požarevac : Sitograf RM
C3  - 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
T1  - Vezikularni sindrom kod svinja – slinavka i šap ili Seneka virus?
EP  - 78
SP  - 72
ER  - 

@conference{
author = "Kureljušić, Branislav and Savić, Božidar and Jezdimirović, Nemanja and Milovanović, Bojan and Maksimović Zorić, Jelena and Dobrosavljević, Ivan and Prodanov Radulović, Jasna and Glišić, Dimitrije and Milićević, Vesna and Bojkovski, Jovan",
year = "2023",
abstract = "Bolesti svinja koje se karakterišu pojavom vezikularnog sindroma su slinavka i šap,
vezikularna bolest svinja, vezikularni stomatitis, vezikularni egzantem svinja i Seneka bolest
svinja. Virus slinavke i šapa, virus vezikularne bolesti svinja i Senecavirus A pripadaju familiji
Picornaviridae.
Slinavka i šap je visoko kontagiozna virusna bolest različitih vrsta papkara koja se kod
svinja karakteriše apatijom, febrom, pojavom vezikula u predelu rila, usne šupljine, papaka i
mlečne žlezde. Klinička slika kod svinja uobičajeno nije teška, a u težim slučajevima može se
javiti eksungulacija. Vrata infekcije su sluznica ždrela i tonzile gde se odvija primarna replikacija
virusa, a potom sledi viremija sa sekundarnom replikacijom virusa na predilekcionim mestima.
Poznato je da inficirana svinja može da proizvede 400 miliona infektivnih doza dnevno i da tako
predstavlja značajan izvor infekcije za druge prijemčive vrste.
Infekcija Senecavirusom A se karakteriše povišenim mortalitetom kod prsadi na sisi do
sedmog dana starosti. Kod priplodnih kategorija svinja, postoji povišena telesna temperatura,
anoreksija, letargija, pojava vezikula na rilu, sluznici usne šupljine i koronarnom rubu papaka.
Pojava bolesti kod svinja koje se karakterišu vezikularnim sindromom uvek izaziva veliku
zabrinutost imajući u vidu da je klinički nemoguće razlikovati lezije koje izaziva virus slinavke i
šapa i drugi virusi. Konačnu dijagnozu je moguće jedino potvrditi u laboratoriji. Obzirom da su
svinje prijemčive za više vrsta virusa koji dovode do vezikularnog sindroma kao i činjenicu da
svinje pozitivne na slinavku i šap izlučuju veliku količinu virusa u spoljašnju sredinu putem
aerosola, blagovremeno utvrđivanje dijagnoze je od prvorazrednog značaja.
Ukoliko postoji sumnja na neku od bolesti koje se karakterišu vezikularnim sindromom
potrebno je bez odlaganja obavestiti nadležnog veterinarskog inspektora i regionalni institut koji
zajedno sa terenskom veterinarskom službom utvrđuju dalji postupak u skladu sa zakonskom
regulativom i sprovode epizootiološki nadzor i uzorkovanje materijala za laboratorijska
ispitivanja. Uzorci prvog prioriteta su pokrovni epitel vezikula, sadržaj vezikula, oralni/nazalni brisevi i uzorci krvi. Laboratorijska dijagnostika omogućava dobijanje rezultata u roku od
nekoliko časova.",
publisher = "Požarevac : Sitograf RM",
journal = "20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja",
title = "Vezikularni sindrom kod svinja – slinavka i šap ili Seneka virus?",
pages = "78-72"
}

Kureljušić, B., Savić, B., Jezdimirović, N., Milovanović, B., Maksimović Zorić, J., Dobrosavljević, I., Prodanov Radulović, J., Glišić, D., Milićević, V.,& Bojkovski, J.. (2023). Vezikularni sindrom kod svinja – slinavka i šap ili Seneka virus?. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
Požarevac : Sitograf RM., 72-78.

Kureljušić B, Savić B, Jezdimirović N, Milovanović B, Maksimović Zorić J, Dobrosavljević I, Prodanov Radulović J, Glišić D, Milićević V, Bojkovski J. Vezikularni sindrom kod svinja – slinavka i šap ili Seneka virus?. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja. 2023;:72-78..

Kureljušić, Branislav, Savić, Božidar, Jezdimirović, Nemanja, Milovanović, Bojan, Maksimović Zorić, Jelena, Dobrosavljević, Ivan, Prodanov Radulović, Jasna, Glišić, Dimitrije, Milićević, Vesna, Bojkovski, Jovan, "Vezikularni sindrom kod svinja – slinavka i šap ili Seneka virus?" in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja (2023):72-78.

TY  - CONF
AU  - Savić, Božidar
AU  - Radanović, Oliver
AU  - Kureljušić, Branislav
AU  - Zdravković, Nemanja
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Maksimović Zorić, Jelena
AU  - Milićević, Vesna
AU  - Pavlović, Ivan
AU  - Stevančević, Ognjen
AU  - Dobrosavljević, Ivan
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/504
AB  - Streptokokone infekcije svinja se pojavljuju u svim zemljama sa intenzivnom svinjarskom
proizvodnjom, a izazivaju ih patogene streptokoke različitih serogrupa. Nekoliko vrsta
streptokoka je ustanovljeno kod svinja, od kojih su neki komensali, a neki patogeni. Najznačajnija
i najrasprostranjenija streptokoka svinja je Streptococcus suis (S. suis), uzročnik septikemičnog
oboljenja ili promena lokalizovanih u organima kod prasadi na sisi, prasadi stare 5 do 10 nedelja
i starijih kategorija svinja uključujući i nazimice, krmače i nerastove. Streptococcus suis je
inkapsulirana Gram-pozitivna koka, svrstana u grupu D prema Lancefield klasifikaciji. Do danas
je utvrđeno 35 kapsluarnih serotiova S. suis, koji se međusobno razlikuju po patogenosti. Većina
sojeva S. suis izolovanih od obolelih svinja pripada serotipovima 1-9, pri čemu je serotip 2
najprevalentniji i najvirulentniji serotip u većini evroazijskih zemalja. Streptokoke mogu na
različite načine da dospeju u organizam životinja. Glavna „ulazna vrata“ infekcije kod prasadi na
sisi predstavlja pupak, kratko posle poroda, ledirana gingiva ili otvorena pulpa kod korekcije zuba,
abrazije kože na ekstremitetima kod neadekvatnih podova, a naročito kada je kod krmača prisutan
MMA sindrom odnosno sindrom postpartalne disgalakcije. Takođe, i lezije kod kupiranja repa i
kastracije muške prasadi mogu predstavljati atrijum za infekciju. Kod latentno inficiranih krmača,
streptokoke naseljavaju tonzile pa se pretpostavlja da se u ovakvim slučajevima prasad mogu
inficirati preko respiratornog sistema. Ako se prasad inficiraju od latentno inficiranih krmača do
ekspresije bolesti dolazi posle imunosupresije.
Prateći zdravstveno stanje svinja u velikim aglomeracijama nam je omogućilo da na celovit način
pratimo oboljenja streptokokne etiologije koja se pojavljuju u više kliničkih i patomorfoloških
oblika. Tako, streptokokna infekcija kod prasadi na sisi i zalučene prasadi se manifestuje kao
streptokokna septikemija novorođene prasadi, streptokokna septikemija prasadi stare 2-3 nedelje,
zatim kao artritis, osteomijelitis, endokarditis, apostematozni miokarditis, meningoencefalitis,
cefalocervikalni limfadenitis, supkutani periartikularni absces, pneumonija i zapaljenje srednjeg
uva. Od oblika streptokokne infekcije kod prasadi na sisi najfrekentnije se javljaju streptokokna
septikemija i artritisi, a kod prasadi iz odgoja meningo-encefalitisi, endokarditis, pneumonija i  
zapaljenje srednjeg uva. Vrlo retko smo imali priliku da detektujemo i cefalo-cervikalni
limfadenitis i periartikularne apcese. Kod krmača, streptokoke su bile odgovorne za razvoj
mastitisa, endometritisa i pojavu abortusa. Najfrekventnije izolovani serotip S. suis u našem
istraživanju je bio serotip 2 (45%), a pored njega detektovani su i serotipovi ½ (17%), 1 (13%), 4
(7%), 7 (6%), 9 (5%), 5 (4%) i serotip 3 (3%), kao i veći broj izolata koje nismo mogli tipizirati.
Streptokokna infekcija svinja predstavlja ozbiljan i značajan zdravstveni problem u većim
aglomeracijama, a karakterišu je različiti putevi infekcije kao i polimorfizom u izražavanju.
AB  - Streptococcal infections of pigs occur in all countries with intensive pig production, and
are caused by pathogenic streptococci of different serogroups. Several species of streptococci have
been found in pigs, some of which are commensal and some are pathogenic. Streptococcus suis
(S. Suis) is one of the most important and widespread pathogens of pigs causing septicemic disease
or localized lesions in different organs in suckling piglets, 5- to 10-week-old piglets, and older
categories of pigs including gilts, sows, and boars. Streptococcus suis is an encapsulated Grampositive cocci, classified in group D according to the Lancefield classification. A total of 35 S.
suis capsular serotypes have been identified to date, which differ in pathogenicity. Most S. suis
strains isolated from diseased pigs belong to serotypes 1-9, with serotype 2 being the most
prevalent and virulent serotype in most eurasian countries. Streptococci can enter into the body in
different ways. The main portals of infection in suckling piglets are umbilical infections shortly
after birth, gum lesions or exposed dental pulp made during tooth cutting, skin injuries on the
extremities caused by abrasive floors, especially when MMA or postpartum dysgalactia syndrome
is present in sows. Castration and tail docking wounds can also be an portals for infection. In
latently infected sows, streptococci inhabit the tonsils, thus it is assumed that piglets can be
 infected through the respiratory system. In cases of infection of piglets from latently infected
sows, the disease occur in piglets after immunosuppression.
Monitoring the health status of pigs in large agglomerations allowed us, to comprehensively
survey of clinical, pathomorphological and etiological features of streptococcal diseases. Thus,
septicemia of newborn piglets, septicemia of 2-3 week old piglets, arthritis, osteomyelitis,
endocarditis, apostematous myocarditis, meningoencephalitis, cephalocervical lymphadenitis,
subcutaneous periarticular abscess, pneumonia and otitis media, were the most severe
manifestation of the disease. The septicemia and arthritis were the most common forms of the
streptococcal disease in suckling piglets, while meningo-encephalitis, endocarditis, pneumonia
and otitis media were the most common streptococcal diseases in weaned piglets. Cephalocervical lymphadenitis and periarticular abscesses were relativly sparsely detected. The most frequently isolated serotype S. suis was serotype 2 (45%), in addition, serotypes ½ (17%), 1 (13%), 4 (7%), 7 (6%), 9 (5%), 5 (4%) and 3 (3%) were also detected, as well as a larger number of isolates that we could not type. Streptococcal infection represents severe and significant health
problem in large pig agglomerations, and is characterized by different routes of infection as well
as polymorphism in expression.
PB  - Požarevac : Sitograf RM
C3  - 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
T1  - Kliničke i patomorfološke karakteristike infekcije svinja sa Streptococcus suis
T1  - Clinical and pathological characteristics of Streptococcus suis infections in pigs
EP  - 71
SP  - 56
ER  - 

@conference{
author = "Savić, Božidar and Radanović, Oliver and Kureljušić, Branislav and Zdravković, Nemanja and Jezdimirović, Nemanja and Milovanović, Bojan and Maksimović Zorić, Jelena and Milićević, Vesna and Pavlović, Ivan and Stevančević, Ognjen and Dobrosavljević, Ivan",
year = "2023",
abstract = "Streptokokone infekcije svinja se pojavljuju u svim zemljama sa intenzivnom svinjarskom
proizvodnjom, a izazivaju ih patogene streptokoke različitih serogrupa. Nekoliko vrsta
streptokoka je ustanovljeno kod svinja, od kojih su neki komensali, a neki patogeni. Najznačajnija
i najrasprostranjenija streptokoka svinja je Streptococcus suis (S. suis), uzročnik septikemičnog
oboljenja ili promena lokalizovanih u organima kod prasadi na sisi, prasadi stare 5 do 10 nedelja
i starijih kategorija svinja uključujući i nazimice, krmače i nerastove. Streptococcus suis je
inkapsulirana Gram-pozitivna koka, svrstana u grupu D prema Lancefield klasifikaciji. Do danas
je utvrđeno 35 kapsluarnih serotiova S. suis, koji se međusobno razlikuju po patogenosti. Većina
sojeva S. suis izolovanih od obolelih svinja pripada serotipovima 1-9, pri čemu je serotip 2
najprevalentniji i najvirulentniji serotip u većini evroazijskih zemalja. Streptokoke mogu na
različite načine da dospeju u organizam životinja. Glavna „ulazna vrata“ infekcije kod prasadi na
sisi predstavlja pupak, kratko posle poroda, ledirana gingiva ili otvorena pulpa kod korekcije zuba,
abrazije kože na ekstremitetima kod neadekvatnih podova, a naročito kada je kod krmača prisutan
MMA sindrom odnosno sindrom postpartalne disgalakcije. Takođe, i lezije kod kupiranja repa i
kastracije muške prasadi mogu predstavljati atrijum za infekciju. Kod latentno inficiranih krmača,
streptokoke naseljavaju tonzile pa se pretpostavlja da se u ovakvim slučajevima prasad mogu
inficirati preko respiratornog sistema. Ako se prasad inficiraju od latentno inficiranih krmača do
ekspresije bolesti dolazi posle imunosupresije.
Prateći zdravstveno stanje svinja u velikim aglomeracijama nam je omogućilo da na celovit način
pratimo oboljenja streptokokne etiologije koja se pojavljuju u više kliničkih i patomorfoloških
oblika. Tako, streptokokna infekcija kod prasadi na sisi i zalučene prasadi se manifestuje kao
streptokokna septikemija novorođene prasadi, streptokokna septikemija prasadi stare 2-3 nedelje,
zatim kao artritis, osteomijelitis, endokarditis, apostematozni miokarditis, meningoencefalitis,
cefalocervikalni limfadenitis, supkutani periartikularni absces, pneumonija i zapaljenje srednjeg
uva. Od oblika streptokokne infekcije kod prasadi na sisi najfrekentnije se javljaju streptokokna
septikemija i artritisi, a kod prasadi iz odgoja meningo-encefalitisi, endokarditis, pneumonija i  
zapaljenje srednjeg uva. Vrlo retko smo imali priliku da detektujemo i cefalo-cervikalni
limfadenitis i periartikularne apcese. Kod krmača, streptokoke su bile odgovorne za razvoj
mastitisa, endometritisa i pojavu abortusa. Najfrekventnije izolovani serotip S. suis u našem
istraživanju je bio serotip 2 (45%), a pored njega detektovani su i serotipovi ½ (17%), 1 (13%), 4
(7%), 7 (6%), 9 (5%), 5 (4%) i serotip 3 (3%), kao i veći broj izolata koje nismo mogli tipizirati.
Streptokokna infekcija svinja predstavlja ozbiljan i značajan zdravstveni problem u većim
aglomeracijama, a karakterišu je različiti putevi infekcije kao i polimorfizom u izražavanju., Streptococcal infections of pigs occur in all countries with intensive pig production, and
are caused by pathogenic streptococci of different serogroups. Several species of streptococci have
been found in pigs, some of which are commensal and some are pathogenic. Streptococcus suis
(S. Suis) is one of the most important and widespread pathogens of pigs causing septicemic disease
or localized lesions in different organs in suckling piglets, 5- to 10-week-old piglets, and older
categories of pigs including gilts, sows, and boars. Streptococcus suis is an encapsulated Grampositive cocci, classified in group D according to the Lancefield classification. A total of 35 S.
suis capsular serotypes have been identified to date, which differ in pathogenicity. Most S. suis
strains isolated from diseased pigs belong to serotypes 1-9, with serotype 2 being the most
prevalent and virulent serotype in most eurasian countries. Streptococci can enter into the body in
different ways. The main portals of infection in suckling piglets are umbilical infections shortly
after birth, gum lesions or exposed dental pulp made during tooth cutting, skin injuries on the
extremities caused by abrasive floors, especially when MMA or postpartum dysgalactia syndrome
is present in sows. Castration and tail docking wounds can also be an portals for infection. In
latently infected sows, streptococci inhabit the tonsils, thus it is assumed that piglets can be
 infected through the respiratory system. In cases of infection of piglets from latently infected
sows, the disease occur in piglets after immunosuppression.
Monitoring the health status of pigs in large agglomerations allowed us, to comprehensively
survey of clinical, pathomorphological and etiological features of streptococcal diseases. Thus,
septicemia of newborn piglets, septicemia of 2-3 week old piglets, arthritis, osteomyelitis,
endocarditis, apostematous myocarditis, meningoencephalitis, cephalocervical lymphadenitis,
subcutaneous periarticular abscess, pneumonia and otitis media, were the most severe
manifestation of the disease. The septicemia and arthritis were the most common forms of the
streptococcal disease in suckling piglets, while meningo-encephalitis, endocarditis, pneumonia
and otitis media were the most common streptococcal diseases in weaned piglets. Cephalocervical lymphadenitis and periarticular abscesses were relativly sparsely detected. The most frequently isolated serotype S. suis was serotype 2 (45%), in addition, serotypes ½ (17%), 1 (13%), 4 (7%), 7 (6%), 9 (5%), 5 (4%) and 3 (3%) were also detected, as well as a larger number of isolates that we could not type. Streptococcal infection represents severe and significant health
problem in large pig agglomerations, and is characterized by different routes of infection as well
as polymorphism in expression.",
publisher = "Požarevac : Sitograf RM",
journal = "20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja",
title = "Kliničke i patomorfološke karakteristike infekcije svinja sa Streptococcus suis, Clinical and pathological characteristics of Streptococcus suis infections in pigs",
pages = "71-56"
}

Savić, B., Radanović, O., Kureljušić, B., Zdravković, N., Jezdimirović, N., Milovanović, B., Maksimović Zorić, J., Milićević, V., Pavlović, I., Stevančević, O.,& Dobrosavljević, I.. (2023). Kliničke i patomorfološke karakteristike infekcije svinja sa Streptococcus suis. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
Požarevac : Sitograf RM., 56-71.

Savić B, Radanović O, Kureljušić B, Zdravković N, Jezdimirović N, Milovanović B, Maksimović Zorić J, Milićević V, Pavlović I, Stevančević O, Dobrosavljević I. Kliničke i patomorfološke karakteristike infekcije svinja sa Streptococcus suis. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja. 2023;:56-71..

Savić, Božidar, Radanović, Oliver, Kureljušić, Branislav, Zdravković, Nemanja, Jezdimirović, Nemanja, Milovanović, Bojan, Maksimović Zorić, Jelena, Milićević, Vesna, Pavlović, Ivan, Stevančević, Ognjen, Dobrosavljević, Ivan, "Kliničke i patomorfološke karakteristike infekcije svinja sa Streptococcus suis" in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja (2023):56-71.

TY  - CONF
AU  - Maksimović Zorić, Jelena
AU  - Veljović, Ljubiša
AU  - Glišić, Dimitrije
AU  - Savić, Božidar
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Maletić, Jelena
AU  - Spalević, Ljiljana
AU  - Kureljušić, Branislav
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/505
AB  - Influenca svinja predstavlja veoma važan zdravstvni i ekonomski problem u
komercijalnom uzgoju svinja. U etiologiji respiratornih oboljenja do kojih dovode dominiraju tri podtipa virusa influence tipa A - H1N1, H1N2 i H3N2, različitih genetskih i antigenskih karakteristika (Detmer, 2017). Iako u neimunom zapatu influenca može ostvariti visok morbiditet (i do 100%), mortalitet je uglavnom nizak (manji od 1%) i zavisi od soja virusa i prisustva drugih infekcija u zapatu (Van Reeth i sar., 2012, Zell i sar., 2013). Kao posledica cirkulacije virusa na
farmi dolazi do direktnih, i mnogo značajnijih, indirektnih gubitaka koji se ogledaju u smanjenju dnevnog prirasta, povećanju utroška hrane za kilogram prirasta, produžetku tova i dr. (Došen i sar., 2008). Na ekonomičnost proizvodnje najznačajnije utiče smanjenje dnevnog prirasta (Calderón Díaz i sar., 2020), a Haden i sar., 2012, su ustanovili da gubici po grlu u slučaju monoinfekcije virusom influence iznose 3,23$. Pored direktnih i indirektnih gubitaka u
proizvodnji, cirkulacija virusa influence u populacijama svinja predstavlja i problem od javnog značaja zbog zoonotskog potencijala koji ovi virusi poseduju i mogućih uzrokovanja oboljenja ljudi. Posle pandemije 2009. godine za koju je utvrđeno da je nastala prilagođavanjem i širenjem reasortiranog virusa svinja u humanoj populaciji (Smith i sar., 2009) opisani su mnogobrojni slučajevi oboljenja ljudi nastali prenošenjem virusa sa svinja na ljude (Hennig i sar., 2022). Iako
su to najčešće incidentni slučajevi oboljenja, a tek u nekoliko navrata oboljenje manje grupe ljudi (Hennig i sar., 2022), potencijal za prenos svinjskih virusa u humanu populaciju je evidentan, što upućuje na neophodnost praćenja raširenosti ove infekcije u zapatima svinja primenom kliničke opservacije i laboratorijskih ispitivanja obolelih.
Cirkulaciju virusa i stepen raširenosti infekcije u jednom zapatu svinja u kome se ne primenjuje vakcinacija kao mera kontrole, najlakše i najekonomičnije je utvrditi primenom laboratorijskog ispitivanja prisustva specifičnih antitela protiv virusa influence tipa A. Imunološki odgovor u vidu sinteze antitela je detektabilan već trećeg dana od nastanka infekcije (Lee i sar., 1995), pri čemu pik dostiže obično između 14. i 21. dana (Radojičić i sar., 2011). Nakon primarne infekcije nastali imunitet je dugotrajan i pruža zaštitu od infekcije istim ili drugim antigeno
sličnim sojem (Van Reeth i sar., 2012). Humoralni imunološki odgovor se ogleda u sintezi specifičnih antitela protiv hemaglutinina, neuraminidaze, nukleoproteina i matriks proteina virusa (Wright i sar., 2007), a laboratorijske metode koje se koriste za njihovu detekciju su imunoenzimski testovi (ELISA), virus neutralizacioni test (VNT) i inhibibicija hemaglutinacije (IHA) (Detmer i sar., 2013). Za testiranje velikog broja uzoraka seruma koje za cilj ima utvrđivanje seroprevalencije u jednom zapatu najpogodnije je koristiti ELISA test, dok se titar
antitela kod pojedinačnih životinja kao i podtip cirkulišućih virusa utvrđuju primenom VNT ili IHA. S' obzirom na činjenicu da je cirkulacija virusa influence tipa A potvrđena na većini velikih komercijalnih farmi u Srbiji (Maksimović Zorić i sar., 2020), izvršeno je ispitivanje seroprevalencije u različitim uzrasnim kategorijama i serotipizacija cirkulišućih virusa.
PB  - Požarevac : Sitograf RM
C3  - 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
T1  - Seroloska ispitivanja influence kod razlicitih uzrasnih kategorija svinja uzgajanih na komercijalnim farmama
EP  - 55
SP  - 48
ER  - 

@conference{
author = "Maksimović Zorić, Jelena and Veljović, Ljubiša and Glišić, Dimitrije and Savić, Božidar and Jezdimirović, Nemanja and Milovanović, Bojan and Maletić, Jelena and Spalević, Ljiljana and Kureljušić, Branislav",
year = "2023",
abstract = "Influenca svinja predstavlja veoma važan zdravstvni i ekonomski problem u
komercijalnom uzgoju svinja. U etiologiji respiratornih oboljenja do kojih dovode dominiraju tri podtipa virusa influence tipa A - H1N1, H1N2 i H3N2, različitih genetskih i antigenskih karakteristika (Detmer, 2017). Iako u neimunom zapatu influenca može ostvariti visok morbiditet (i do 100%), mortalitet je uglavnom nizak (manji od 1%) i zavisi od soja virusa i prisustva drugih infekcija u zapatu (Van Reeth i sar., 2012, Zell i sar., 2013). Kao posledica cirkulacije virusa na
farmi dolazi do direktnih, i mnogo značajnijih, indirektnih gubitaka koji se ogledaju u smanjenju dnevnog prirasta, povećanju utroška hrane za kilogram prirasta, produžetku tova i dr. (Došen i sar., 2008). Na ekonomičnost proizvodnje najznačajnije utiče smanjenje dnevnog prirasta (Calderón Díaz i sar., 2020), a Haden i sar., 2012, su ustanovili da gubici po grlu u slučaju monoinfekcije virusom influence iznose 3,23$. Pored direktnih i indirektnih gubitaka u
proizvodnji, cirkulacija virusa influence u populacijama svinja predstavlja i problem od javnog značaja zbog zoonotskog potencijala koji ovi virusi poseduju i mogućih uzrokovanja oboljenja ljudi. Posle pandemije 2009. godine za koju je utvrđeno da je nastala prilagođavanjem i širenjem reasortiranog virusa svinja u humanoj populaciji (Smith i sar., 2009) opisani su mnogobrojni slučajevi oboljenja ljudi nastali prenošenjem virusa sa svinja na ljude (Hennig i sar., 2022). Iako
su to najčešće incidentni slučajevi oboljenja, a tek u nekoliko navrata oboljenje manje grupe ljudi (Hennig i sar., 2022), potencijal za prenos svinjskih virusa u humanu populaciju je evidentan, što upućuje na neophodnost praćenja raširenosti ove infekcije u zapatima svinja primenom kliničke opservacije i laboratorijskih ispitivanja obolelih.
Cirkulaciju virusa i stepen raširenosti infekcije u jednom zapatu svinja u kome se ne primenjuje vakcinacija kao mera kontrole, najlakše i najekonomičnije je utvrditi primenom laboratorijskog ispitivanja prisustva specifičnih antitela protiv virusa influence tipa A. Imunološki odgovor u vidu sinteze antitela je detektabilan već trećeg dana od nastanka infekcije (Lee i sar., 1995), pri čemu pik dostiže obično između 14. i 21. dana (Radojičić i sar., 2011). Nakon primarne infekcije nastali imunitet je dugotrajan i pruža zaštitu od infekcije istim ili drugim antigeno
sličnim sojem (Van Reeth i sar., 2012). Humoralni imunološki odgovor se ogleda u sintezi specifičnih antitela protiv hemaglutinina, neuraminidaze, nukleoproteina i matriks proteina virusa (Wright i sar., 2007), a laboratorijske metode koje se koriste za njihovu detekciju su imunoenzimski testovi (ELISA), virus neutralizacioni test (VNT) i inhibibicija hemaglutinacije (IHA) (Detmer i sar., 2013). Za testiranje velikog broja uzoraka seruma koje za cilj ima utvrđivanje seroprevalencije u jednom zapatu najpogodnije je koristiti ELISA test, dok se titar
antitela kod pojedinačnih životinja kao i podtip cirkulišućih virusa utvrđuju primenom VNT ili IHA. S' obzirom na činjenicu da je cirkulacija virusa influence tipa A potvrđena na većini velikih komercijalnih farmi u Srbiji (Maksimović Zorić i sar., 2020), izvršeno je ispitivanje seroprevalencije u različitim uzrasnim kategorijama i serotipizacija cirkulišućih virusa.",
publisher = "Požarevac : Sitograf RM",
journal = "20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja",
title = "Seroloska ispitivanja influence kod razlicitih uzrasnih kategorija svinja uzgajanih na komercijalnim farmama",
pages = "55-48"
}

Maksimović Zorić, J., Veljović, L., Glišić, D., Savić, B., Jezdimirović, N., Milovanović, B., Maletić, J., Spalević, L.,& Kureljušić, B.. (2023). Seroloska ispitivanja influence kod razlicitih uzrasnih kategorija svinja uzgajanih na komercijalnim farmama. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
Požarevac : Sitograf RM., 48-55.

Maksimović Zorić J, Veljović L, Glišić D, Savić B, Jezdimirović N, Milovanović B, Maletić J, Spalević L, Kureljušić B. Seroloska ispitivanja influence kod razlicitih uzrasnih kategorija svinja uzgajanih na komercijalnim farmama. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja. 2023;:48-55..

Maksimović Zorić, Jelena, Veljović, Ljubiša, Glišić, Dimitrije, Savić, Božidar, Jezdimirović, Nemanja, Milovanović, Bojan, Maletić, Jelena, Spalević, Ljiljana, Kureljušić, Branislav, "Seroloska ispitivanja influence kod razlicitih uzrasnih kategorija svinja uzgajanih na komercijalnim farmama" in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja (2023):48-55.

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Jezdimirović, Nemanja
AU  - Milićević, Vesna
AU  - Glišić, Dimitrije
AU  - Milovanović, Bojan
AU  - Maletić, Jelena
AU  - Maksimović Zorić, Jelena
AU  - Prodanov Radulović, Jasna
AU  - Savić, Božidar
PY  - 2023
UR  - https://swineflu.eu/wp-content/uploads/2023/06/ESFLU-Scientific-Meeting-Barcelona-2023-proceedings-3.pdf
UR  - https://reponivs.nivs.rs/handle/123456789/506
AB  - Swine influenza A is the most common respiratory disease in pig production around the world, as well as an important respiratory pathogen that affects pig health, welfare, productivity, and has zoonotic potential. Internal biosecurity practices during the pre-weaning period are critical in farms with an endemic presence of swine influenza to prevent infection and stop transmission. The current study aimed to determine whether there is a link between internal biosecurity and maintenance of influenza on the farm.
A Biocheck online survey (https://biocheckgent.com) was used to assess biosecurity at one farrow to wean pig farm in Serbia. Each assessed category was scored on a scale of 0 (worst-case scenario) to 100% (the best scenario). In the nursery, 10 udder skin wipes were obtained from lactating sows, whereas in the weaned piglets, 10 samples of oral fluid were collected and analysed for the presence of swine influenza A RNA using real-time RT-PCR. Throughout a year of monitoring, samples were collected six times every two months.
The external biosecurity assessment resulted in a score of 88%, compared to the Serbian average of 69% and the global average of 76%. External biosecurity assessments revealed the lowest scores for animal transport, carcass removal, and manure removal (71%). Internal biosecurity revealed a score of 67%, compared to the national average of 44% and the global average of 69%. Internal biosecurity was confirmed to have the lowest percentage score (36%) for the farrowing and suckling period. In this study, the overall biosecurity score for the pig farm was 78%. The national average was 57%, while the global average was 73%.
During 12 months of monitoring, swine influenza A virus positivity rate in investigated farm remained high in both set of samples. For udder skin wipes, the positivity rate ranged from 30% to 60%, and for oral fluid samples, it ranged from 50% to 80%. There was no seasonal variation in the positivity rate.
This study revealed low level of internal biosecurity for the farrowing and suckling period. The following suggestions were made to the farm manager: avoid moving pigs between litters after they are 3 days old; avoid using nurse sows; farm workers should change disposable gloves between litters; not entering in
farrowing crates and perform daily disinfection of fomites. Implementing vaccination is another preventive measure that needs to be discussed.
This study helped to identify gaps on biosecurity and risky practices in the pig farm evaluated.
PB  - ESFLU
C3  - ESFLU Scientific meeting
T1  - Low internal biosecurity: factor that favours maintenance of influenza on commercial farrow to wean pig farm in Serbia
ER  - 

@conference{
author = "Kureljušić, Branislav and Jezdimirović, Nemanja and Milićević, Vesna and Glišić, Dimitrije and Milovanović, Bojan and Maletić, Jelena and Maksimović Zorić, Jelena and Prodanov Radulović, Jasna and Savić, Božidar",
year = "2023",
abstract = "Swine influenza A is the most common respiratory disease in pig production around the world, as well as an important respiratory pathogen that affects pig health, welfare, productivity, and has zoonotic potential. Internal biosecurity practices during the pre-weaning period are critical in farms with an endemic presence of swine influenza to prevent infection and stop transmission. The current study aimed to determine whether there is a link between internal biosecurity and maintenance of influenza on the farm.
A Biocheck online survey (https://biocheckgent.com) was used to assess biosecurity at one farrow to wean pig farm in Serbia. Each assessed category was scored on a scale of 0 (worst-case scenario) to 100% (the best scenario). In the nursery, 10 udder skin wipes were obtained from lactating sows, whereas in the weaned piglets, 10 samples of oral fluid were collected and analysed for the presence of swine influenza A RNA using real-time RT-PCR. Throughout a year of monitoring, samples were collected six times every two months.
The external biosecurity assessment resulted in a score of 88%, compared to the Serbian average of 69% and the global average of 76%. External biosecurity assessments revealed the lowest scores for animal transport, carcass removal, and manure removal (71%). Internal biosecurity revealed a score of 67%, compared to the national average of 44% and the global average of 69%. Internal biosecurity was confirmed to have the lowest percentage score (36%) for the farrowing and suckling period. In this study, the overall biosecurity score for the pig farm was 78%. The national average was 57%, while the global average was 73%.
During 12 months of monitoring, swine influenza A virus positivity rate in investigated farm remained high in both set of samples. For udder skin wipes, the positivity rate ranged from 30% to 60%, and for oral fluid samples, it ranged from 50% to 80%. There was no seasonal variation in the positivity rate.
This study revealed low level of internal biosecurity for the farrowing and suckling period. The following suggestions were made to the farm manager: avoid moving pigs between litters after they are 3 days old; avoid using nurse sows; farm workers should change disposable gloves between litters; not entering in
farrowing crates and perform daily disinfection of fomites. Implementing vaccination is another preventive measure that needs to be discussed.
This study helped to identify gaps on biosecurity and risky practices in the pig farm evaluated.",
publisher = "ESFLU",
journal = "ESFLU Scientific meeting",
title = "Low internal biosecurity: factor that favours maintenance of influenza on commercial farrow to wean pig farm in Serbia"
}

Kureljušić, B., Jezdimirović, N., Milićević, V., Glišić, D., Milovanović, B., Maletić, J., Maksimović Zorić, J., Prodanov Radulović, J.,& Savić, B.. (2023). Low internal biosecurity: factor that favours maintenance of influenza on commercial farrow to wean pig farm in Serbia. in ESFLU Scientific meeting
ESFLU..

Kureljušić B, Jezdimirović N, Milićević V, Glišić D, Milovanović B, Maletić J, Maksimović Zorić J, Prodanov Radulović J, Savić B. Low internal biosecurity: factor that favours maintenance of influenza on commercial farrow to wean pig farm in Serbia. in ESFLU Scientific meeting. 2023;..

Kureljušić, Branislav, Jezdimirović, Nemanja, Milićević, Vesna, Glišić, Dimitrije, Milovanović, Bojan, Maletić, Jelena, Maksimović Zorić, Jelena, Prodanov Radulović, Jasna, Savić, Božidar, "Low internal biosecurity: factor that favours maintenance of influenza on commercial farrow to wean pig farm in Serbia" in ESFLU Scientific meeting (2023).

TY  - CONF
AU  - Ninković, Milan
AU  - Zdravković, Nemanja
AU  - Jezdimirović, Nemanja
AU  - Arsić, Sveta
AU  - Bojkovski, Jovan
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/823
AB  - Lameness causes significant economic losses in dairy cows. Lesions of the foot are the cause
of about 85% of all lameness in dairy cows. In addition, lameness can be localized in other
places of the locomotor system such as joints, muscles, and skin. The aim of this study was to
show the distribution of locomotor lesions in dairy cows. A total of 144 Simmental dairy
cows (36 primiparous and 108 multiparous) from 10 small dairy farms located in the Macva
district, Serbia were observed during regular hoof trimming. All cows were housed in a tiedholding
system. The clinical examination focused on all possible alternations on the observed
hooves and legs. Lesions of the horn, skin, joints, and leg injuries were noted. Of the 144
animals presenting for a hoof trim, 49 cows (34.0%) had no locomotor lesions noted. In this
study, lesions were present in 95 (66,0%) of all examined cows. Locomotor lesions of the
horn were detected in 82.4% (61/74 of cases), skin 2.7%, joints in 10.8%, and leg injuries in
4.05% of the cases in multiparous cows. Thus, lesions of the horn were detected in 61.9%
(13/21 of cases), skin 4.7%, joint in 23.8% and leg injuries in 9.5% of the cases in
primiparous cows. Our results show that lesions on the hooves are the most dominant site of
the locomotor system.
C3  - 14. International Scientific Agricultural Symposium "Agrosym 2023"
T1  - Distribution of locomotor lesions in dairy cows in Serbia
EP  - 597
SP  - 597
ER  - 

@conference{
author = "Ninković, Milan and Zdravković, Nemanja and Jezdimirović, Nemanja and Arsić, Sveta and Bojkovski, Jovan",
year = "2023",
abstract = "Lameness causes significant economic losses in dairy cows. Lesions of the foot are the cause
of about 85% of all lameness in dairy cows. In addition, lameness can be localized in other
places of the locomotor system such as joints, muscles, and skin. The aim of this study was to
show the distribution of locomotor lesions in dairy cows. A total of 144 Simmental dairy
cows (36 primiparous and 108 multiparous) from 10 small dairy farms located in the Macva
district, Serbia were observed during regular hoof trimming. All cows were housed in a tiedholding
system. The clinical examination focused on all possible alternations on the observed
hooves and legs. Lesions of the horn, skin, joints, and leg injuries were noted. Of the 144
animals presenting for a hoof trim, 49 cows (34.0%) had no locomotor lesions noted. In this
study, lesions were present in 95 (66,0%) of all examined cows. Locomotor lesions of the
horn were detected in 82.4% (61/74 of cases), skin 2.7%, joints in 10.8%, and leg injuries in
4.05% of the cases in multiparous cows. Thus, lesions of the horn were detected in 61.9%
(13/21 of cases), skin 4.7%, joint in 23.8% and leg injuries in 9.5% of the cases in
primiparous cows. Our results show that lesions on the hooves are the most dominant site of
the locomotor system.",
journal = "14. International Scientific Agricultural Symposium "Agrosym 2023"",
title = "Distribution of locomotor lesions in dairy cows in Serbia",
pages = "597-597"
}

Ninković, M., Zdravković, N., Jezdimirović, N., Arsić, S.,& Bojkovski, J.. (2023). Distribution of locomotor lesions in dairy cows in Serbia. in 14. International Scientific Agricultural Symposium "Agrosym 2023", 597-597.

Ninković M, Zdravković N, Jezdimirović N, Arsić S, Bojkovski J. Distribution of locomotor lesions in dairy cows in Serbia. in 14. International Scientific Agricultural Symposium "Agrosym 2023". 2023;:597-597..

Ninković, Milan, Zdravković, Nemanja, Jezdimirović, Nemanja, Arsić, Sveta, Bojkovski, Jovan, "Distribution of locomotor lesions in dairy cows in Serbia" in 14. International Scientific Agricultural Symposium "Agrosym 2023" (2023):597-597.

TY  - JOUR
AU  - Spalević, Ljiljana
AU  - Zdravković, Nemanja
AU  - Žutić, Jadranka
AU  - Vojinović, Dragica
AU  - Milićević, Vesna
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Jasna
AU  - Radanović, Oliver
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/756
AB  - Poultry represents a significant global reservoir of Salmonella spp. Poultry salmonellosis results in 
significant economic losses, and some serovars also have zoonotic potential. Some poultry can be infected with Salmo nella species without showing clinical signs of the disease, but it is a significant source of the spread of the infection. 
Clinical symptoms range from digestive problems (white diarrhea, malabsorption) to bacteremia and death. This study 
aimed to retrospectively show the presence of bacteria Salmonella enterica subspecies enterica of various serovars 
in poultry in the Belgrade epizootiological area in a period of six years (2014-2019). A total of 4580 samples were 
examined, including incubated eggs, dead chickens, broiler feces, and laying hens with 207 positive samples. Salmo nella was isolated by standard microbiological methods followed by serological typing. In the examined period, the 
prevalence of poultry salmonella was 4.52%. The highest number of examined samples was recorded in 2017 (879) 
and positive in 2018 (65), while the lowest prevalence was recorded during the year 2016 with 7 positive samples. Of 
all isolated and serotyped Salmonella, the most commonly isolated serovar was S. Enteritidis (65.28%), followed by
S. Infantis (21.30%), S. Mbandaka (6.02%), S. Senftenberg (3.24%), S. Typhimurium (1.85%), S. Agona (0.93%), S. 
Taksony (0.93%), and the least common is S. Tshiongwe (0.46%). The first report of serovars: S. Agona, S. Taksony 
and S. Tshiongwe have been during 2018. The highest number of positive specimens was found in laying hens faces 
(116 of 921 tested), broiler faces (73 of 1147), chickens carcasses (12 of 1443), and incubated eggs (6 of 1069). Com plete eradication of Salmonella from production is a challenging goal because of a heterogeneous serovars pool and 
various sources of infection. Prevention is the best tool for controlling Salmonella: hygiene, biosecurity, and where 
applicable - vaccination. It is a great responsibility of the poultry farmers to apply the existing standards and to improve 
the new ones.
PB  - Athens : Hellenic veterinary medical Society
T2  - Journal of the Hellenic Veterinary Medical Society
T1  - A retrospective study on the isolated strains of Salmonella in poultry
EP  - 5898
IS  - 3
SP  - 5893
VL  - 74
DO  - 10.12681/jhvms.25005
ER  - 

@article{
author = "Spalević, Ljiljana and Zdravković, Nemanja and Žutić, Jadranka and Vojinović, Dragica and Milićević, Vesna and Jezdimirović, Nemanja and Kureljušić, Jasna and Radanović, Oliver",
year = "2023",
abstract = "Poultry represents a significant global reservoir of Salmonella spp. Poultry salmonellosis results in 
significant economic losses, and some serovars also have zoonotic potential. Some poultry can be infected with Salmo nella species without showing clinical signs of the disease, but it is a significant source of the spread of the infection. 
Clinical symptoms range from digestive problems (white diarrhea, malabsorption) to bacteremia and death. This study 
aimed to retrospectively show the presence of bacteria Salmonella enterica subspecies enterica of various serovars 
in poultry in the Belgrade epizootiological area in a period of six years (2014-2019). A total of 4580 samples were 
examined, including incubated eggs, dead chickens, broiler feces, and laying hens with 207 positive samples. Salmo nella was isolated by standard microbiological methods followed by serological typing. In the examined period, the 
prevalence of poultry salmonella was 4.52%. The highest number of examined samples was recorded in 2017 (879) 
and positive in 2018 (65), while the lowest prevalence was recorded during the year 2016 with 7 positive samples. Of 
all isolated and serotyped Salmonella, the most commonly isolated serovar was S. Enteritidis (65.28%), followed by
S. Infantis (21.30%), S. Mbandaka (6.02%), S. Senftenberg (3.24%), S. Typhimurium (1.85%), S. Agona (0.93%), S. 
Taksony (0.93%), and the least common is S. Tshiongwe (0.46%). The first report of serovars: S. Agona, S. Taksony 
and S. Tshiongwe have been during 2018. The highest number of positive specimens was found in laying hens faces 
(116 of 921 tested), broiler faces (73 of 1147), chickens carcasses (12 of 1443), and incubated eggs (6 of 1069). Com plete eradication of Salmonella from production is a challenging goal because of a heterogeneous serovars pool and 
various sources of infection. Prevention is the best tool for controlling Salmonella: hygiene, biosecurity, and where 
applicable - vaccination. It is a great responsibility of the poultry farmers to apply the existing standards and to improve 
the new ones.",
publisher = "Athens : Hellenic veterinary medical Society",
journal = "Journal of the Hellenic Veterinary Medical Society",
title = "A retrospective study on the isolated strains of Salmonella in poultry",
pages = "5898-5893",
number = "3",
volume = "74",
doi = "10.12681/jhvms.25005"
}

Spalević, L., Zdravković, N., Žutić, J., Vojinović, D., Milićević, V., Jezdimirović, N., Kureljušić, J.,& Radanović, O.. (2023). A retrospective study on the isolated strains of Salmonella in poultry. in Journal of the Hellenic Veterinary Medical Society
Athens : Hellenic veterinary medical Society., 74(3), 5893-5898.
https://doi.org/10.12681/jhvms.25005

Spalević L, Zdravković N, Žutić J, Vojinović D, Milićević V, Jezdimirović N, Kureljušić J, Radanović O. A retrospective study on the isolated strains of Salmonella in poultry. in Journal of the Hellenic Veterinary Medical Society. 2023;74(3):5893-5898.
doi:10.12681/jhvms.25005 .

Spalević, Ljiljana, Zdravković, Nemanja, Žutić, Jadranka, Vojinović, Dragica, Milićević, Vesna, Jezdimirović, Nemanja, Kureljušić, Jasna, Radanović, Oliver, "A retrospective study on the isolated strains of Salmonella in poultry" in Journal of the Hellenic Veterinary Medical Society, 74, no. 3 (2023):5893-5898,
https://doi.org/10.12681/jhvms.25005 . .

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Maletić, Jelena
AU  - Milićević, Vesna
AU  - Savić, Božidar
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Jasna
AU  - Grubač, Siniša
AU  - Prodanov Radulović, Jasna
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/556
AB  - In Serbia, there are different animal production systems, including extensive ones, which are
common and traditional in Serbia. Nowadays, extensive pig production with very low or almost
no biosecurity measures plays an important role in the spread of ASF and other infectious
diseases. Extensive farming systems are traditionally practiced in villages, hamlets, and forests,
usually near riverbanks. In Serbia, there are different types of extensive production systems:
small farms, backyards, semi-free-range, free-range, and a small percentage of organic pig
production units. In traditional systems, pig production can also be divided into indoor and
outdoor housing. However, it is not easy to make a clear distinction between extensive indoor
and outdoor units. In traditional backyard housing systems, pigs are not confined to the units at
all times, and often there is no complete fencing. According to Serbian law, disease surveillance
is mandatory in all pig production. However, local veterinarians are mainly focused on the control
and diagnosis of transboundary infectious diseases such as ASF and CSF. For these reasons, many
other parasitic, bacterial, and sometimes viral infections are detected but underestimated.
During 2019-2023, we retrospectively analyzed the most common diseases in pigs from
traditional extensive husbandry necropsied in the Institute of Veterinary Medicine of Serbia and
the Scientific Veterinary Institute "Novi Sad". Among the most common parasitic diseases in pigs
in extensive husbandry are ascariasis and trichurosis. As for bacterial pathogens, Escherichia coli
and enteric clostridial infections, Pasteurella multocida, Glaesserella parasuis, Streptococcus spp.,
and Salmonella spp. were the most frequently isolated bacteria from various organs of the
examined pigs. The viral pathogens most commonly detected were suid herpesvirus 1 (Aujeszky's
disease) and porcine parvovirus (PPV), in addition to ASF, which was confirmed in infected
counties nationwide. Low biosecurity measures or lack of external biosecurity measures in
extensive swine production farms pose a high risk for transmission of various pathogens,
including not only diseases caused by conditionally pathogenic microorganisms, but also
notifiable diseases that can have a significant negative impact on the country's economy.
PB  - COST (European Cooperation in Science and Technology)
C3  - The 2023 Annual General Meeting of the COST action BETTER
T1  - Extensive pig production sector in Serbia – biosecurity concerns and diseases transmission
EP  - 24
SP  - 24
ER  - 

@conference{
author = "Kureljušić, Branislav and Maletić, Jelena and Milićević, Vesna and Savić, Božidar and Jezdimirović, Nemanja and Kureljušić, Jasna and Grubač, Siniša and Prodanov Radulović, Jasna",
year = "2023",
abstract = "In Serbia, there are different animal production systems, including extensive ones, which are
common and traditional in Serbia. Nowadays, extensive pig production with very low or almost
no biosecurity measures plays an important role in the spread of ASF and other infectious
diseases. Extensive farming systems are traditionally practiced in villages, hamlets, and forests,
usually near riverbanks. In Serbia, there are different types of extensive production systems:
small farms, backyards, semi-free-range, free-range, and a small percentage of organic pig
production units. In traditional systems, pig production can also be divided into indoor and
outdoor housing. However, it is not easy to make a clear distinction between extensive indoor
and outdoor units. In traditional backyard housing systems, pigs are not confined to the units at
all times, and often there is no complete fencing. According to Serbian law, disease surveillance
is mandatory in all pig production. However, local veterinarians are mainly focused on the control
and diagnosis of transboundary infectious diseases such as ASF and CSF. For these reasons, many
other parasitic, bacterial, and sometimes viral infections are detected but underestimated.
During 2019-2023, we retrospectively analyzed the most common diseases in pigs from
traditional extensive husbandry necropsied in the Institute of Veterinary Medicine of Serbia and
the Scientific Veterinary Institute "Novi Sad". Among the most common parasitic diseases in pigs
in extensive husbandry are ascariasis and trichurosis. As for bacterial pathogens, Escherichia coli
and enteric clostridial infections, Pasteurella multocida, Glaesserella parasuis, Streptococcus spp.,
and Salmonella spp. were the most frequently isolated bacteria from various organs of the
examined pigs. The viral pathogens most commonly detected were suid herpesvirus 1 (Aujeszky's
disease) and porcine parvovirus (PPV), in addition to ASF, which was confirmed in infected
counties nationwide. Low biosecurity measures or lack of external biosecurity measures in
extensive swine production farms pose a high risk for transmission of various pathogens,
including not only diseases caused by conditionally pathogenic microorganisms, but also
notifiable diseases that can have a significant negative impact on the country's economy.",
publisher = "COST (European Cooperation in Science and Technology)",
journal = "The 2023 Annual General Meeting of the COST action BETTER",
title = "Extensive pig production sector in Serbia – biosecurity concerns and diseases transmission",
pages = "24-24"
}

Kureljušić, B., Maletić, J., Milićević, V., Savić, B., Jezdimirović, N., Kureljušić, J., Grubač, S.,& Prodanov Radulović, J.. (2023). Extensive pig production sector in Serbia – biosecurity concerns and diseases transmission. in The 2023 Annual General Meeting of the COST action BETTER
COST (European Cooperation in Science and Technology)., 24-24.

Kureljušić B, Maletić J, Milićević V, Savić B, Jezdimirović N, Kureljušić J, Grubač S, Prodanov Radulović J. Extensive pig production sector in Serbia – biosecurity concerns and diseases transmission. in The 2023 Annual General Meeting of the COST action BETTER. 2023;:24-24..

Kureljušić, Branislav, Maletić, Jelena, Milićević, Vesna, Savić, Božidar, Jezdimirović, Nemanja, Kureljušić, Jasna, Grubač, Siniša, Prodanov Radulović, Jasna, "Extensive pig production sector in Serbia – biosecurity concerns and diseases transmission" in The 2023 Annual General Meeting of the COST action BETTER (2023):24-24.