TY  - CONF
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Branislav
AU  - Savić, Božidar
AU  - Milovanović, Bojan
AU  - Glišić, Dimitrije
AU  - Maletić, Jelena
AU  - Šolaja, Sofija
AU  - Milićević, Vesna
PY  - 2024
UR  - https://reponivs.nivs.rs/handle/123456789/952
AB  - Дивље свиње могу бити резервоари различитих бактерија, вируса и паразита и
могу се пренети на домаће свиње па и на људе индиректним или директним
контактом. Порцине цитомегаловирус (ПЦМВ) препознат је као главни
узрочник атрофичног ринитиса код свиња свих старосних категорија.
Међународни комитет за таксономију вируса (ИТЦВ) је порцине
цитомегаловирус сврстао у suid betaherpesvirus 2 (SuBHV2), и припада
подфамилији Betaherpesvirinae и фамилији Herpesviridae, али није сврстан ни у
један род. Генетска истраживања су показала да је ПЦМВ генетски сроднији
хуманим херпес вирусима (ХХВ) 6А, 6Б и 7. Поред тога, доказано је да ПЦМВ
доприноси репродуктивним проблемима код крмача и резултира раним
неонаталним губицима. Инфекција ПЦМВ-ом је раширена широм света и има
високу преваленцију, посебно у земљама са интензивном производњом свиња.
Клинички пролази непримећено због стеченог имунитета запата, и обично се
јавља код млађих категорија животиња. Нажалост, сама болест и инфекција су
углавном занемарени.
Како бисмо открили улогу дивљих свиња у епидемиологији ПЦМВ-а,
користили смо реал-тиме ПЦР тестирање 50 узорака (лимфни чвор, слезина и
бубрег) пореклом од одстрељених дивљих свиња.
Испитивање је потврдило присуство генома ПЦМВ у 4/50 (8%) узорака. Ови
резултати указују на релативно ниску али не и занемарљиву преваленцију
вируса у популацији дивљих свиња, што може да представља значајан ризик и
за популацију домаћих свиња.
AB  - Wild boars can be reservoirs of various bacteria, viruses, and parasites and can be
transmitted to domestic pigs and even humans through indirect or direct contact.
Porcine cytomegalovirus (PCMV) is recognized as the main cause of atrophic rhinitis
in pigs of all age categories. The International Committee on Taxonomy of Viruses
(ICTV) has classified porcine cytomegalovirus into suid betaherpesvirus 2
(SuBHV2), belonging to the subfamily Betaherpesvirinae and family Herpesviridae,
but it is not classified into any genus. Genetic research has shown that PCMV is
genetically closer to human herpes viruses (HHV) 6A, 6B, and 7. Additionally, it has
been proven that PCMV contributes to reproductive problems in sows and results in
early neonatal losses. PCMV infection is widespread worldwide and has a high
prevalence, especially in countries with intensive pig production. Clinically, it often
goes unnoticed due to acquired maternal immunity and usually occurs in younger
animal categories. Unfortunately, the disease itself and the infection are largely
neglected.
To discover the role of wild boars in PCMV epidemiology, we used real-time PCR
testing of 50 samples (lymph nodes, spleen, and kidney) originating from shot wild
boars.
Testing confirmed the presence of PCMV genome in 4 out of 50 (8%) samples. These
results indicate a relatively low but not negligible prevalence of the virus in the wild
boar population, which may pose a significant risk to the domestic pig population.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
T1  - Prva molekularna detekcija porcine citomegalovirusa kod divljih svinja u Srbiji
T1  - First molecular detection of porcine cytomegalovirus in wild boars in Serbia
EP  - 79
SP  - 78
ER  - 

@conference{
author = "Jezdimirović, Nemanja and Kureljušić, Branislav and Savić, Božidar and Milovanović, Bojan and Glišić, Dimitrije and Maletić, Jelena and Šolaja, Sofija and Milićević, Vesna",
year = "2024",
abstract = "Дивље свиње могу бити резервоари различитих бактерија, вируса и паразита и
могу се пренети на домаће свиње па и на људе индиректним или директним
контактом. Порцине цитомегаловирус (ПЦМВ) препознат је као главни
узрочник атрофичног ринитиса код свиња свих старосних категорија.
Међународни комитет за таксономију вируса (ИТЦВ) је порцине
цитомегаловирус сврстао у suid betaherpesvirus 2 (SuBHV2), и припада
подфамилији Betaherpesvirinae и фамилији Herpesviridae, али није сврстан ни у
један род. Генетска истраживања су показала да је ПЦМВ генетски сроднији
хуманим херпес вирусима (ХХВ) 6А, 6Б и 7. Поред тога, доказано је да ПЦМВ
доприноси репродуктивним проблемима код крмача и резултира раним
неонаталним губицима. Инфекција ПЦМВ-ом је раширена широм света и има
високу преваленцију, посебно у земљама са интензивном производњом свиња.
Клинички пролази непримећено због стеченог имунитета запата, и обично се
јавља код млађих категорија животиња. Нажалост, сама болест и инфекција су
углавном занемарени.
Како бисмо открили улогу дивљих свиња у епидемиологији ПЦМВ-а,
користили смо реал-тиме ПЦР тестирање 50 узорака (лимфни чвор, слезина и
бубрег) пореклом од одстрељених дивљих свиња.
Испитивање је потврдило присуство генома ПЦМВ у 4/50 (8%) узорака. Ови
резултати указују на релативно ниску али не и занемарљиву преваленцију
вируса у популацији дивљих свиња, што може да представља значајан ризик и
за популацију домаћих свиња., Wild boars can be reservoirs of various bacteria, viruses, and parasites and can be
transmitted to domestic pigs and even humans through indirect or direct contact.
Porcine cytomegalovirus (PCMV) is recognized as the main cause of atrophic rhinitis
in pigs of all age categories. The International Committee on Taxonomy of Viruses
(ICTV) has classified porcine cytomegalovirus into suid betaherpesvirus 2
(SuBHV2), belonging to the subfamily Betaherpesvirinae and family Herpesviridae,
but it is not classified into any genus. Genetic research has shown that PCMV is
genetically closer to human herpes viruses (HHV) 6A, 6B, and 7. Additionally, it has
been proven that PCMV contributes to reproductive problems in sows and results in
early neonatal losses. PCMV infection is widespread worldwide and has a high
prevalence, especially in countries with intensive pig production. Clinically, it often
goes unnoticed due to acquired maternal immunity and usually occurs in younger
animal categories. Unfortunately, the disease itself and the infection are largely
neglected.
To discover the role of wild boars in PCMV epidemiology, we used real-time PCR
testing of 50 samples (lymph nodes, spleen, and kidney) originating from shot wild
boars.
Testing confirmed the presence of PCMV genome in 4 out of 50 (8%) samples. These
results indicate a relatively low but not negligible prevalence of the virus in the wild
boar population, which may pose a significant risk to the domestic pig population.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.",
title = "Prva molekularna detekcija porcine citomegalovirusa kod divljih svinja u Srbiji, First molecular detection of porcine cytomegalovirus in wild boars in Serbia",
pages = "79-78"
}

Jezdimirović, N., Kureljušić, B., Savić, B., Milovanović, B., Glišić, D., Maletić, J., Šolaja, S.,& Milićević, V.. (2024). Prva molekularna detekcija porcine citomegalovirusa kod divljih svinja u Srbiji. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 78-79.

Jezdimirović N, Kureljušić B, Savić B, Milovanović B, Glišić D, Maletić J, Šolaja S, Milićević V. Prva molekularna detekcija porcine citomegalovirusa kod divljih svinja u Srbiji. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.. 2024;:78-79..

Jezdimirović, Nemanja, Kureljušić, Branislav, Savić, Božidar, Milovanović, Bojan, Glišić, Dimitrije, Maletić, Jelena, Šolaja, Sofija, Milićević, Vesna, "Prva molekularna detekcija porcine citomegalovirusa kod divljih svinja u Srbiji" in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god. (2024):78-79.

TY  - CONF
AU  - Savić, Božidar
AU  - Milićević, Vesna
AU  - Kureljušić, Branislav
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Maksimović Zorić, Jelena
AU  - Stevnčević, Ognjen
PY  - 2024
UR  - https://reponivs.nivs.rs/handle/123456789/953
AB  - Репродуктивни и респираторни синдром свиња (енгл. Porcine Reproductive and Respiratory
Syndrome – PRRS), је контагиозна вирусна афекција свиња која тренутно представља
економски најзначајније инфективно обољење свиња, ендемично у многим земљама у
свету укључујучи и нашу земљу. PRRS је узрокован са вирусом репродуктивног и
респираторног синдрома свиња (енгл. Porcine Reproductive and Respiratory Syndrome Virus
– PRRSV), а с краја 90-их година прошлог века, када је обољење по први пут
дијагностиковано у нашој земљи, постоји релативно ограничен број епидемиолошких
студија овог обољења и молекуларних истраживања овог вируса који циркулишу у
популацији свиња. Описана су два генотипа PRRSV: тип-1 или Европски тип (Lelystad -
прототип) и тип-2 или Амерички тип (VR-2332 – прототип). Од недавно, PRRSV тип-1 и
тип-2 су класификовани као две засебне врсте унутар рода Betaarterivirus и то као
Betaarterivirus suid 1 (PRRSV1) и Betaarterivirus suid 2 (PRRSV2). У оквиру генотипа 1
(PRRSV1) се разликују 4 генетске линије (подтипа) (1, 2, 3 и 4) у које су сврстани изолати
вируса пореклом из различитих географских региона Европе. Унутар подтипова 1 и 3, се
диференцирају кластери 1А-1Г и 3А-3Г док подтип 2 чини јединствена група изолата, без
дефинисаних кластера. У нашој земљи, PRRS је био искључиво узрокован генотипом 1
(PRRSV1), међутим, 2022 године, детектован је и генотип 2 вируса (PRRSV2), на фарми
која је вршила увоз свиња из Европске уније. Анализом генома овог вируса је установљено
да је најсличнији тзв. вакциналним-сојевима (vaccine-like strain), односно да је вирус
највероватније пореклом из вакцине (МLV PRRSV2 вакцина) која је употребљена за
имунизацију свиња против PRRSV2 у земљи извозници. Циљ овог истраживањ је био да
се установи генетски диверзитет изолата PRRSV1 пореклом са фарми свиња из наше земље
у периоду од 2012 до 2022 године. У ту сврху, извршено је секвенцирање 36 ОРФ5 гена
изолата PRRSV1 коришћењем Сангер методе, које су потом поређене и анализиране
заједно са 106 секвенци ОРФ5 гена PRRSV1 из генетских линија 1, 2 и 3, које репрезентују
комплетан спектар генетског диверзитета ових подтипова (секвенце кластера 1А-1Г, 3А-
3Г и линије 2), применом различитих модула са предефинисаним параметарима у оквиру
софтверских пакета CLC – MainWorkbench и Mega X. Прикупљене секвнеце ОРФ5 гена су
депоноване у „NCBI“ бази биоинформатичких података. Филогенетском анализом је
установљено да су сви изолати PRRSV1 детектовани у периооду од 2012 до 2022 године у
нашој земљи груписани у два подтипа, односно подтип 1 и 3. У оквиру линије 1, се налази
7 изолата и то: 2 изолата у кластеру 1А, 2 у кластеру 1Б, 2 у кластеру 1Д и један изолат у
кластеру 1Ф. У оквиру линије 2, 29 секвенци је груписано у кластер 3Ц. Добијени
резултати представљају важне информације за будуће епидемиолошке анализе PRRSV1
инфекције укључујући утврђивање повезаности односно сродности између изолата вируса,
поређење нових секвенци са секвенцама пореклом од вакциналних сојева вируса,
разликовање вакциналних од „дивљих“ сојева вируса и утврђивање „уноса“ нових вируса
у популацију. Оваква епидемиолошка истраживања треба искористити за установљавање
критичних тачака у биосигурносним мерама на конкретним фармама, те имплементирати
одговарајуће промене како би се PRRSV инфекција успешно превенирала и контролисала.
AB  - Porcine Reproductive and Respiratory Syndrome (PRRS) is a contagious viral disease
of swine that currently represents the most economically significant infectious disease
of pigs, endemic in many countries worldwide, including Serbia. PRRS is caused by the
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). Since the late 1990s,
when the disease was first diagnosed in the Serbia, there have been only few
epidemiological and molecular studies on circulating PPRS-viruses. Two genotypes of
PRRSV have been described: type 1 or European type (prototype Lelystad) and type 2
or American type (prototype VR-2332). Recently, PRRSV type 1 and type 2 have been
classified as two separate species within the genus Betaarterivirus, namely
Betaarterivirus suid 1 (PRRSV1) and Betaarterivirus suid 2 (PRRSV2). Within
genotype 1 (PRRSV1), four genetic lineages (subtypes) (1, 2, 3, and 4) have been
distinguished, in which isolates from different geographic regions of Europe are
classified. Within subtypes 1 and 3, clusters 1A-1G and 3A-3G are further differentiated,
while subtype 2 consists of a unique group of isolates, without defined clusters. In Serbia,
PRRS was exclusively caused by genotype 1 (PRRSV1); however, in 2022, a genotype
2 (PRRSV2) was detected on a farm that imported pigs from the European Union.
Genome analysis of this virus revealed its similarity to vaccine-like strains, indicating
that the virus most likely originated from a vaccine (MLV PRRSV2 vaccine) used for
immunization against PRRSV2 in the exporting country.
The aim of this study was to establish the genetic diversity of PRRSV1 isolates
originating from pig farms in Serbia from 2012 to 2022. For this purpose, sequencing of
36 ORF5 gene of PRRSV1 was performed using the Sanger method, which were then
compared and analyzed together with 106 ORF5 gene sequences of PRRSV1 from
genetic lineages 1, 2, and 3, representing the full range of genetic diversity of this
subtype (sequences from 1A-1G, 3A-3G clusters, and lineage 2), by using different
modules with predefined parameters within the software packages CLC –
MainWorkbench and Mega X. The obtained ORF5 gene sequences were deposited in the
NCBI database. Phylogenetic analysis revealed that all PRRSV1 isolates detected in the
Serbia from 2012 to 2022 were grouped into two subtypes, subtype 1 and 3. Within
lineage 1, there were 7 isolates: 2 in cluster 1A, 2 in cluster 1B, 2 in cluster 1D, and one
isolate in cluster 1F. Within lineage 2, 29 sequences were grouped in cluster 3C.
The obtained results provide important information for future epidemiological studies of
PRRSV1 infection, including the relatedness between isolates, comparing new obtianed
sequences with sequences originating from vaccine strains, differentiating vaccine
strains from "wild" strains, and determining the introduction of new strains into the
population. Such epidemiological studies can be used for find critical points in the
biosecurity on the given farms and implement changes in the others to prevent and
control PRRSV infection.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
T1  - Genetski diverzitet ORF5 gena virusa reproduktivnog i respiratornog sindroma svinja tip 1 od 2012 do 2022 godine
T1  - Genetic diversity of the ORF5 gene of type 1 porcine reproductive and respiratory syndrome virus in Serbia from 2012 to 2022
EP  - 103
SP  - 102
ER  - 

@conference{
author = "Savić, Božidar and Milićević, Vesna and Kureljušić, Branislav and Jezdimirović, Nemanja and Milovanović, Bojan and Maksimović Zorić, Jelena and Stevnčević, Ognjen",
year = "2024",
abstract = "Репродуктивни и респираторни синдром свиња (енгл. Porcine Reproductive and Respiratory
Syndrome – PRRS), је контагиозна вирусна афекција свиња која тренутно представља
економски најзначајније инфективно обољење свиња, ендемично у многим земљама у
свету укључујучи и нашу земљу. PRRS је узрокован са вирусом репродуктивног и
респираторног синдрома свиња (енгл. Porcine Reproductive and Respiratory Syndrome Virus
– PRRSV), а с краја 90-их година прошлог века, када је обољење по први пут
дијагностиковано у нашој земљи, постоји релативно ограничен број епидемиолошких
студија овог обољења и молекуларних истраживања овог вируса који циркулишу у
популацији свиња. Описана су два генотипа PRRSV: тип-1 или Европски тип (Lelystad -
прототип) и тип-2 или Амерички тип (VR-2332 – прототип). Од недавно, PRRSV тип-1 и
тип-2 су класификовани као две засебне врсте унутар рода Betaarterivirus и то као
Betaarterivirus suid 1 (PRRSV1) и Betaarterivirus suid 2 (PRRSV2). У оквиру генотипа 1
(PRRSV1) се разликују 4 генетске линије (подтипа) (1, 2, 3 и 4) у које су сврстани изолати
вируса пореклом из различитих географских региона Европе. Унутар подтипова 1 и 3, се
диференцирају кластери 1А-1Г и 3А-3Г док подтип 2 чини јединствена група изолата, без
дефинисаних кластера. У нашој земљи, PRRS је био искључиво узрокован генотипом 1
(PRRSV1), међутим, 2022 године, детектован је и генотип 2 вируса (PRRSV2), на фарми
која је вршила увоз свиња из Европске уније. Анализом генома овог вируса је установљено
да је најсличнији тзв. вакциналним-сојевима (vaccine-like strain), односно да је вирус
највероватније пореклом из вакцине (МLV PRRSV2 вакцина) која је употребљена за
имунизацију свиња против PRRSV2 у земљи извозници. Циљ овог истраживањ је био да
се установи генетски диверзитет изолата PRRSV1 пореклом са фарми свиња из наше земље
у периоду од 2012 до 2022 године. У ту сврху, извршено је секвенцирање 36 ОРФ5 гена
изолата PRRSV1 коришћењем Сангер методе, које су потом поређене и анализиране
заједно са 106 секвенци ОРФ5 гена PRRSV1 из генетских линија 1, 2 и 3, које репрезентују
комплетан спектар генетског диверзитета ових подтипова (секвенце кластера 1А-1Г, 3А-
3Г и линије 2), применом различитих модула са предефинисаним параметарима у оквиру
софтверских пакета CLC – MainWorkbench и Mega X. Прикупљене секвнеце ОРФ5 гена су
депоноване у „NCBI“ бази биоинформатичких података. Филогенетском анализом је
установљено да су сви изолати PRRSV1 детектовани у периооду од 2012 до 2022 године у
нашој земљи груписани у два подтипа, односно подтип 1 и 3. У оквиру линије 1, се налази
7 изолата и то: 2 изолата у кластеру 1А, 2 у кластеру 1Б, 2 у кластеру 1Д и један изолат у
кластеру 1Ф. У оквиру линије 2, 29 секвенци је груписано у кластер 3Ц. Добијени
резултати представљају важне информације за будуће епидемиолошке анализе PRRSV1
инфекције укључујући утврђивање повезаности односно сродности између изолата вируса,
поређење нових секвенци са секвенцама пореклом од вакциналних сојева вируса,
разликовање вакциналних од „дивљих“ сојева вируса и утврђивање „уноса“ нових вируса
у популацију. Оваква епидемиолошка истраживања треба искористити за установљавање
критичних тачака у биосигурносним мерама на конкретним фармама, те имплементирати
одговарајуће промене како би се PRRSV инфекција успешно превенирала и контролисала., Porcine Reproductive and Respiratory Syndrome (PRRS) is a contagious viral disease
of swine that currently represents the most economically significant infectious disease
of pigs, endemic in many countries worldwide, including Serbia. PRRS is caused by the
Porcine Reproductive and Respiratory Syndrome Virus (PRRSV). Since the late 1990s,
when the disease was first diagnosed in the Serbia, there have been only few
epidemiological and molecular studies on circulating PPRS-viruses. Two genotypes of
PRRSV have been described: type 1 or European type (prototype Lelystad) and type 2
or American type (prototype VR-2332). Recently, PRRSV type 1 and type 2 have been
classified as two separate species within the genus Betaarterivirus, namely
Betaarterivirus suid 1 (PRRSV1) and Betaarterivirus suid 2 (PRRSV2). Within
genotype 1 (PRRSV1), four genetic lineages (subtypes) (1, 2, 3, and 4) have been
distinguished, in which isolates from different geographic regions of Europe are
classified. Within subtypes 1 and 3, clusters 1A-1G and 3A-3G are further differentiated,
while subtype 2 consists of a unique group of isolates, without defined clusters. In Serbia,
PRRS was exclusively caused by genotype 1 (PRRSV1); however, in 2022, a genotype
2 (PRRSV2) was detected on a farm that imported pigs from the European Union.
Genome analysis of this virus revealed its similarity to vaccine-like strains, indicating
that the virus most likely originated from a vaccine (MLV PRRSV2 vaccine) used for
immunization against PRRSV2 in the exporting country.
The aim of this study was to establish the genetic diversity of PRRSV1 isolates
originating from pig farms in Serbia from 2012 to 2022. For this purpose, sequencing of
36 ORF5 gene of PRRSV1 was performed using the Sanger method, which were then
compared and analyzed together with 106 ORF5 gene sequences of PRRSV1 from
genetic lineages 1, 2, and 3, representing the full range of genetic diversity of this
subtype (sequences from 1A-1G, 3A-3G clusters, and lineage 2), by using different
modules with predefined parameters within the software packages CLC –
MainWorkbench and Mega X. The obtained ORF5 gene sequences were deposited in the
NCBI database. Phylogenetic analysis revealed that all PRRSV1 isolates detected in the
Serbia from 2012 to 2022 were grouped into two subtypes, subtype 1 and 3. Within
lineage 1, there were 7 isolates: 2 in cluster 1A, 2 in cluster 1B, 2 in cluster 1D, and one
isolate in cluster 1F. Within lineage 2, 29 sequences were grouped in cluster 3C.
The obtained results provide important information for future epidemiological studies of
PRRSV1 infection, including the relatedness between isolates, comparing new obtianed
sequences with sequences originating from vaccine strains, differentiating vaccine
strains from "wild" strains, and determining the introduction of new strains into the
population. Such epidemiological studies can be used for find critical points in the
biosecurity on the given farms and implement changes in the others to prevent and
control PRRSV infection.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.",
title = "Genetski diverzitet ORF5 gena virusa reproduktivnog i respiratornog sindroma svinja tip 1 od 2012 do 2022 godine, Genetic diversity of the ORF5 gene of type 1 porcine reproductive and respiratory syndrome virus in Serbia from 2012 to 2022",
pages = "103-102"
}

Savić, B., Milićević, V., Kureljušić, B., Jezdimirović, N., Milovanović, B., Maksimović Zorić, J.,& Stevnčević, O.. (2024). Genetski diverzitet ORF5 gena virusa reproduktivnog i respiratornog sindroma svinja tip 1 od 2012 do 2022 godine. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 102-103.

Savić B, Milićević V, Kureljušić B, Jezdimirović N, Milovanović B, Maksimović Zorić J, Stevnčević O. Genetski diverzitet ORF5 gena virusa reproduktivnog i respiratornog sindroma svinja tip 1 od 2012 do 2022 godine. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.. 2024;:102-103..

Savić, Božidar, Milićević, Vesna, Kureljušić, Branislav, Jezdimirović, Nemanja, Milovanović, Bojan, Maksimović Zorić, Jelena, Stevnčević, Ognjen, "Genetski diverzitet ORF5 gena virusa reproduktivnog i respiratornog sindroma svinja tip 1 od 2012 do 2022 godine" in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god. (2024):102-103.

TY  - CONF
AU  - Maksimović Zorić, Jelena
AU  - Veljović, Ljubiša
AU  - Glišić, Dimitrije
AU  - Kureljušić, Branislav
AU  - Jezdimirović, Nemanja
AU  - Stanojević, Slobodan
AU  - Maletić, Jelena
AU  - Ninković, Milan
AU  - Aksić, Đorđe
AU  - Savić, Božidar
PY  - 2024
UR  - https://reponivs.nivs.rs/handle/123456789/951
AB  - Афричка куга свиња (АКС) је први пут потврђена на територији Републике
Србије у јулу 2019. године, код домаћих свиња на епизоотиолошком подручју
Града Београда. Епизоотиолошким увиђајем је установљено да је неодговорно
понашање људи довело до уноса вируса из околних земаља и ширења заразе. У
првом таласу регистрована су жаришта у три насељена места, а применом
законом прописаних мера, болест је стављена под контролу и одјављена
децембра 2019. године. Упркос поновном уносу вируса из околних земаља и
ширењу заразе у популацијама дивљих и домаћих свиња у североисточним,
централним, источним и јужним деловима земље, ситуација на територији
епизоотиолошког подручја Града Београда у периоду од 2020. до 2022. године
је била стабилна. Поновно избијање заразе десило се 9. јуна 2023. године када
је болест потврђена код угинуле дивље свиње пронађене у ловишту
"Панчевачки рит", на територији општине Палилула. Већ 12. јуна потврђен је и
први случај код екстензивно узгајаних домаћих свиња у насљеном месту
Крњача. Зараза је убрзо потврђена и код дивљих свиња суседног ловишта "Рит"
и домаћих свиња других насељених места општине Палилула (Бесни Фок,
Дунавац, Јабучки Рит, Ковилово, Падинска Скела, Борча, Овча, Сланци, Велико
Село, Вишњица). У периоду од 9. јуна до 5. августа болест је потврђена на 157
газдинстава, односно код 223 домаће и код 110 дивљих свиња, те је посумњано
да су активности људи уз неадекватне биосигурносне мере на газдинствима
допринеле настанку епизоотије. Током јула и августа 2023. године зараза је
потврђена и код дивљих и домаћих свиња на територијама општина Земун,
Гроцка, Чукарица и Обреновац, где је регистровано 34 позитивна газдинстава и
једно ловиште. Од 26. септембра до 28. децембра није било нових случајева
заразе на епизоотиолошком подручју Града Београда, те је зараза одјављена 26.
децембра, односно 3 месеца после последњег потврђеног случаја АКС.
AB  - African swine fever (ASF) was first confirmed in the Republic of Serbia in July 2019,
in domestic pigs settled within the Belgrade epizootiology area. Through an
epizootiological investigation, it was concluded that the outbreak was a result of
irresponsible human behaviour which led to the introduction of the virus from
surrounding countries and its further spread. In the first wave, three outbreaks were
detected in three villages and by implementing regulatory measures for disease
control, the infection was successfully resolved in December 2019. Although the virus
re-entered from neighboring countries and spread across the northeast, central,
eastern, and southern regions, there were no new disease outbreaks in the Belgrade
epizootiological unit during the 2020-2022 period. Despite efforts to control the
infection, the disease reappeared in June 2023, spreading rapidly among wild boars
and domestic pigs in various settlements and hunting grounds of Palilula municipality.
During the two-month period, the disease was confirmed on 157 holdings,
respectively in 223 domestic pigs and 110 wild boars, implying the significance of
human behaviour and poor biosecurity measures on the epizootic spread of the
disease. During July and August 2023, the infection was confirmed in wild boars and
domestic pigs in the municipalities Zemun, Grocka, Čukarica, and Obrenovac, where
34 holdings and one hunting ground were declared positive. From September 26th to
December 28th, there were no new cases of infection in the Belgrade epizootiology
area, and the infection was resolved on December 26th, i.e. 3 months after the last
confirmed case of ASF.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
T1  - Afrička kuga svinja - epizootiološka situacija na teritoriji okruga grada Beograda u periodu od 2019. do 2023. godine
T1  - African swine fever - epizootiological situation in the Belgrade city area in the period from 2019 to 2023
EP  - 91
SP  - 90
ER  - 

@conference{
author = "Maksimović Zorić, Jelena and Veljović, Ljubiša and Glišić, Dimitrije and Kureljušić, Branislav and Jezdimirović, Nemanja and Stanojević, Slobodan and Maletić, Jelena and Ninković, Milan and Aksić, Đorđe and Savić, Božidar",
year = "2024",
abstract = "Афричка куга свиња (АКС) је први пут потврђена на територији Републике
Србије у јулу 2019. године, код домаћих свиња на епизоотиолошком подручју
Града Београда. Епизоотиолошким увиђајем је установљено да је неодговорно
понашање људи довело до уноса вируса из околних земаља и ширења заразе. У
првом таласу регистрована су жаришта у три насељена места, а применом
законом прописаних мера, болест је стављена под контролу и одјављена
децембра 2019. године. Упркос поновном уносу вируса из околних земаља и
ширењу заразе у популацијама дивљих и домаћих свиња у североисточним,
централним, источним и јужним деловима земље, ситуација на територији
епизоотиолошког подручја Града Београда у периоду од 2020. до 2022. године
је била стабилна. Поновно избијање заразе десило се 9. јуна 2023. године када
је болест потврђена код угинуле дивље свиње пронађене у ловишту
"Панчевачки рит", на територији општине Палилула. Већ 12. јуна потврђен је и
први случај код екстензивно узгајаних домаћих свиња у насљеном месту
Крњача. Зараза је убрзо потврђена и код дивљих свиња суседног ловишта "Рит"
и домаћих свиња других насељених места општине Палилула (Бесни Фок,
Дунавац, Јабучки Рит, Ковилово, Падинска Скела, Борча, Овча, Сланци, Велико
Село, Вишњица). У периоду од 9. јуна до 5. августа болест је потврђена на 157
газдинстава, односно код 223 домаће и код 110 дивљих свиња, те је посумњано
да су активности људи уз неадекватне биосигурносне мере на газдинствима
допринеле настанку епизоотије. Током јула и августа 2023. године зараза је
потврђена и код дивљих и домаћих свиња на територијама општина Земун,
Гроцка, Чукарица и Обреновац, где је регистровано 34 позитивна газдинстава и
једно ловиште. Од 26. септембра до 28. децембра није било нових случајева
заразе на епизоотиолошком подручју Града Београда, те је зараза одјављена 26.
децембра, односно 3 месеца после последњег потврђеног случаја АКС., African swine fever (ASF) was first confirmed in the Republic of Serbia in July 2019,
in domestic pigs settled within the Belgrade epizootiology area. Through an
epizootiological investigation, it was concluded that the outbreak was a result of
irresponsible human behaviour which led to the introduction of the virus from
surrounding countries and its further spread. In the first wave, three outbreaks were
detected in three villages and by implementing regulatory measures for disease
control, the infection was successfully resolved in December 2019. Although the virus
re-entered from neighboring countries and spread across the northeast, central,
eastern, and southern regions, there were no new disease outbreaks in the Belgrade
epizootiological unit during the 2020-2022 period. Despite efforts to control the
infection, the disease reappeared in June 2023, spreading rapidly among wild boars
and domestic pigs in various settlements and hunting grounds of Palilula municipality.
During the two-month period, the disease was confirmed on 157 holdings,
respectively in 223 domestic pigs and 110 wild boars, implying the significance of
human behaviour and poor biosecurity measures on the epizootic spread of the
disease. During July and August 2023, the infection was confirmed in wild boars and
domestic pigs in the municipalities Zemun, Grocka, Čukarica, and Obrenovac, where
34 holdings and one hunting ground were declared positive. From September 26th to
December 28th, there were no new cases of infection in the Belgrade epizootiology
area, and the infection was resolved on December 26th, i.e. 3 months after the last
confirmed case of ASF.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.",
title = "Afrička kuga svinja - epizootiološka situacija na teritoriji okruga grada Beograda u periodu od 2019. do 2023. godine, African swine fever - epizootiological situation in the Belgrade city area in the period from 2019 to 2023",
pages = "91-90"
}

Maksimović Zorić, J., Veljović, L., Glišić, D., Kureljušić, B., Jezdimirović, N., Stanojević, S., Maletić, J., Ninković, M., Aksić, Đ.,& Savić, B.. (2024). Afrička kuga svinja - epizootiološka situacija na teritoriji okruga grada Beograda u periodu od 2019. do 2023. godine. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 90-91.

Maksimović Zorić J, Veljović L, Glišić D, Kureljušić B, Jezdimirović N, Stanojević S, Maletić J, Ninković M, Aksić Đ, Savić B. Afrička kuga svinja - epizootiološka situacija na teritoriji okruga grada Beograda u periodu od 2019. do 2023. godine. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.. 2024;:90-91..

Maksimović Zorić, Jelena, Veljović, Ljubiša, Glišić, Dimitrije, Kureljušić, Branislav, Jezdimirović, Nemanja, Stanojević, Slobodan, Maletić, Jelena, Ninković, Milan, Aksić, Đorđe, Savić, Božidar, "Afrička kuga svinja - epizootiološka situacija na teritoriji okruga grada Beograda u periodu od 2019. do 2023. godine" in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god. (2024):90-91.

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Vićić, Ivan
AU  - Bradić, Milijana
AU  - Maletić, Jelena
AU  - Jezdimirović, Nemanja
AU  - Savić, Božidar
AU  - Milovanović, Bojan
AU  - Karabasil, Neđeljko
PY  - 2024
UR  - https://reponivs.nivs.rs/handle/123456789/955
AB  - Интензивирањем бројлерске производње дошло је до значајног повећања
преваленције различитих патолошких стања чија основна етиологија почива у
самом технолошком процесу производње. Појава контактног дерматитиса на
плантарној кожи екстремитета („foot pad dermatitis“), затим на скочном зглобу
(„hock burns“) и на грудима („breast burns“) данас представља врло раширену
појаву у интензивној производњи, наносећи значајне економске губитке услед
смањеног прираста и одбацивања трупова на линији клања. Поред интензивирања
бројлерске производње значајан утицај на њихову појаву имају исхрана, услови и
начин држања (врста простирке) и генетска предиспозиција. Најзначајнији
фактор ризика за настанак лезија је влажна простирка посебно у комбинацији са
штетним дејством амонијака. Појава лезија има веома велики значај као
индикатор добробити имајући у виду да постоје претпоставке да су установљене
лезије врло болне и да често онемогућавају нормално кретање пилића.
Макроскопским прегледом лезија на плантарној површини уочавају се
инфламаторне лезије праћене некрозом на јастучићима табана и/или на прстима.
Лезије се ређе могу установити на тибиометатарзалним зглобовима. Код благог
облика постоји дисколорација на кожи, хиперкератоза, а у тежим случајевима
јавња се едем, ерозије и улцерације.
Хистопатолошки, благе лезије се карактеришу умереном хиперплазијом и/или
хиперкератозом епидермиса, конгестијом и едемом, уз присуство благог
инфламаторног инфилтрата у форми периваскулитиса и субепителијалне
инфилтрације мононуклеарним ћелијама и мањим бројем гранулоцита. Умерене
суперфицијелне лезије се карактеришу врло израженом хиперплазијом и
хиперкератозом епидермиса, егзоцитозом, појавом пустула и красти, конгестијом
и инфилтрацијом дермиса мононуклеарним и гранулоцитиним инфилтратом.
Тешке, дубоке лезије се карактеришу некрозом епидермиса који је замењен
некротичним гнојним садржајем, појавом гранулационог ткива, израженом
инфламаторном инфилтрацијом (периваскулитис и субепителна инфилтрација)
доминантно хетерофилним гранулоцитима и мононуклеарним ћелијама.
Имајући у виду да је појава контактног дерматитиса све учесталија појава како на
фармама бројлерских пилића тако и на кланици приликом прегледа трупова на
линија клања неопходно је имплементирати програм контроле овог патолошког
стања и на тај начин побољшати добробит и обезбедити производњу квалитетног
и безбедног пилећег меса.
AB  - The intensification of broiler production has led to a significant increase in the
prevalence of various pathological conditions, whose basic etiology lies in the
production process itself. The occurrence of contact dermatitis on the plantar skin of
extremities ("foot pad dermatitis"), then on the hock joint ("hock burns"), and on the
breasts ("breast burns") is today a very widespread phenomenon in intensive production,
causing significant economic losses due to reduced growth and carcass rejection on the
slaughter line. In addition to the intensification of broiler production, significant factors
influencing their occurrence are nutrition, housing conditions (type of bedding), and
genetic predisposition. The most significant risk factor for lesion formation is wet
bedding, especially in combination with the harmful effects of ammonia. The
occurrence of lesions is very important as an indicator of welfare, considering that there
are assumptions that established lesions are very painful and often prevent normal
chicken movement. Macroscopic examination of lesions on the plantar surface reveals
inflammatory lesions accompanied by necrosis on the foot pads and/or toes. Lesions are
less commonly found on the tibiotarsal joints. In mild forms, discoloration of the skin,
hyperkeratosis, and in severe cases, edema, erosions, and ulcerations occur.
Histopathologically, mild lesions are characterized by moderate epidermal hyperplasia
and/or hyperkeratosis, congestion and edema, with the presence of mild inflammatory
infiltrate in the form of perivasculitis and subepithelial infiltration of mononuclear cells
and a small number of granulocytes. Moderate superficial lesions are characterized by
very pronounced epidermal hyperplasia and hyperkeratosis, exocytosis, appearance of
pustules and crusts, congestion, and infiltration of the dermis with mononuclear and
granulocytic infiltrate. Severe, deep lesions are characterized by epidermal necrosis
replaced by necrotic purulent content, appearance of granulation tissue, pronounced
inflammatory infiltration (perivasculitis and subepithelial infiltration) predominantly
with heterophilic granulocytes and mononuclear cells. Considering that the occurrence
of contact dermatitis is becoming more frequent both on broiler farms and in
slaughterhouses during carcass examination on the slaughter line, it is necessary to
implement a control program for this pathological condition
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
T1  - Kontaktni pododermatitis kod brojlerskih pilića – patološki aspekt -
T1  - Contact pododermatitis in broiler chickens – pathological aspect –
EP  - 147
SP  - 146
ER  - 

@conference{
author = "Kureljušić, Branislav and Vićić, Ivan and Bradić, Milijana and Maletić, Jelena and Jezdimirović, Nemanja and Savić, Božidar and Milovanović, Bojan and Karabasil, Neđeljko",
year = "2024",
abstract = "Интензивирањем бројлерске производње дошло је до значајног повећања
преваленције различитих патолошких стања чија основна етиологија почива у
самом технолошком процесу производње. Појава контактног дерматитиса на
плантарној кожи екстремитета („foot pad dermatitis“), затим на скочном зглобу
(„hock burns“) и на грудима („breast burns“) данас представља врло раширену
појаву у интензивној производњи, наносећи значајне економске губитке услед
смањеног прираста и одбацивања трупова на линији клања. Поред интензивирања
бројлерске производње значајан утицај на њихову појаву имају исхрана, услови и
начин држања (врста простирке) и генетска предиспозиција. Најзначајнији
фактор ризика за настанак лезија је влажна простирка посебно у комбинацији са
штетним дејством амонијака. Појава лезија има веома велики значај као
индикатор добробити имајући у виду да постоје претпоставке да су установљене
лезије врло болне и да често онемогућавају нормално кретање пилића.
Макроскопским прегледом лезија на плантарној површини уочавају се
инфламаторне лезије праћене некрозом на јастучићима табана и/или на прстима.
Лезије се ређе могу установити на тибиометатарзалним зглобовима. Код благог
облика постоји дисколорација на кожи, хиперкератоза, а у тежим случајевима
јавња се едем, ерозије и улцерације.
Хистопатолошки, благе лезије се карактеришу умереном хиперплазијом и/или
хиперкератозом епидермиса, конгестијом и едемом, уз присуство благог
инфламаторног инфилтрата у форми периваскулитиса и субепителијалне
инфилтрације мононуклеарним ћелијама и мањим бројем гранулоцита. Умерене
суперфицијелне лезије се карактеришу врло израженом хиперплазијом и
хиперкератозом епидермиса, егзоцитозом, појавом пустула и красти, конгестијом
и инфилтрацијом дермиса мононуклеарним и гранулоцитиним инфилтратом.
Тешке, дубоке лезије се карактеришу некрозом епидермиса који је замењен
некротичним гнојним садржајем, појавом гранулационог ткива, израженом
инфламаторном инфилтрацијом (периваскулитис и субепителна инфилтрација)
доминантно хетерофилним гранулоцитима и мононуклеарним ћелијама.
Имајући у виду да је појава контактног дерматитиса све учесталија појава како на
фармама бројлерских пилића тако и на кланици приликом прегледа трупова на
линија клања неопходно је имплементирати програм контроле овог патолошког
стања и на тај начин побољшати добробит и обезбедити производњу квалитетног
и безбедног пилећег меса., The intensification of broiler production has led to a significant increase in the
prevalence of various pathological conditions, whose basic etiology lies in the
production process itself. The occurrence of contact dermatitis on the plantar skin of
extremities ("foot pad dermatitis"), then on the hock joint ("hock burns"), and on the
breasts ("breast burns") is today a very widespread phenomenon in intensive production,
causing significant economic losses due to reduced growth and carcass rejection on the
slaughter line. In addition to the intensification of broiler production, significant factors
influencing their occurrence are nutrition, housing conditions (type of bedding), and
genetic predisposition. The most significant risk factor for lesion formation is wet
bedding, especially in combination with the harmful effects of ammonia. The
occurrence of lesions is very important as an indicator of welfare, considering that there
are assumptions that established lesions are very painful and often prevent normal
chicken movement. Macroscopic examination of lesions on the plantar surface reveals
inflammatory lesions accompanied by necrosis on the foot pads and/or toes. Lesions are
less commonly found on the tibiotarsal joints. In mild forms, discoloration of the skin,
hyperkeratosis, and in severe cases, edema, erosions, and ulcerations occur.
Histopathologically, mild lesions are characterized by moderate epidermal hyperplasia
and/or hyperkeratosis, congestion and edema, with the presence of mild inflammatory
infiltrate in the form of perivasculitis and subepithelial infiltration of mononuclear cells
and a small number of granulocytes. Moderate superficial lesions are characterized by
very pronounced epidermal hyperplasia and hyperkeratosis, exocytosis, appearance of
pustules and crusts, congestion, and infiltration of the dermis with mononuclear and
granulocytic infiltrate. Severe, deep lesions are characterized by epidermal necrosis
replaced by necrotic purulent content, appearance of granulation tissue, pronounced
inflammatory infiltration (perivasculitis and subepithelial infiltration) predominantly
with heterophilic granulocytes and mononuclear cells. Considering that the occurrence
of contact dermatitis is becoming more frequent both on broiler farms and in
slaughterhouses during carcass examination on the slaughter line, it is necessary to
implement a control program for this pathological condition",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.",
title = "Kontaktni pododermatitis kod brojlerskih pilića – patološki aspekt -, Contact pododermatitis in broiler chickens – pathological aspect –",
pages = "147-146"
}

Kureljušić, B., Vićić, I., Bradić, M., Maletić, J., Jezdimirović, N., Savić, B., Milovanović, B.,& Karabasil, N.. (2024). Kontaktni pododermatitis kod brojlerskih pilića – patološki aspekt -. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 146-147.

Kureljušić B, Vićić I, Bradić M, Maletić J, Jezdimirović N, Savić B, Milovanović B, Karabasil N. Kontaktni pododermatitis kod brojlerskih pilića – patološki aspekt -. in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god.. 2024;:146-147..

Kureljušić, Branislav, Vićić, Ivan, Bradić, Milijana, Maletić, Jelena, Jezdimirović, Nemanja, Savić, Božidar, Milovanović, Bojan, Karabasil, Neđeljko, "Kontaktni pododermatitis kod brojlerskih pilića – patološki aspekt -" in XXVI Simpozijum epizootiologa i epidemiolooga (XXVI Epizootilološki dani), Banja Koviljača  10 - 12. april 2024. god. (2024):146-147.

TY  - CONF
AU  - Pavlovic, Ivan
AU  - Savic, Bozidar
AU  - Zdravkovic, Nemanja
AU  - Radanovic, Oliver
AU  - Bojkovski, Jovan
AU  - Pavlovic, Marija
AU  - Tasic, Aleksandra
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/859
AB  - Introduction: Neonatal enteropathies of piglets were recognized as a serious problem of the
modern pig industry. Today it is known that it is a multicausal disease caused by numerous
agents of bacterial, viral and parasitic etiology (Jacobson, 2022) The aim of our work is to
point out the importance of parasitic infections in this disease.
Materials and Methods: In period 2017-2020 a total of 337 pigs, 2-21 weeks old, were
exanimate. After routine necropsy, parasitological, bacteriological and viral evaluations were
performed, as required to establish the cause of disease in each pig. To parasitological
examination we used faecal swab, gut contents and a mucous scrape of gut which we
examined with Sheathers sugar flotation and in direct smears stained with Gimsa strain.
Results: During our examination Eimeria sp. were detected at two week old piglet at 4.22%,
Ispsora suis at 2-4 week old piglet at 12,34% and cryptosporidial organisms were detected in
the microvillus brush border in the intestine of the pigs ranged from 7-12 weeks old at
61,36%. Based on the time of onset of neonatal enteropathies, Cryptosporidium sp. was
confirmed as the main parasitic agent of its occurrence. These results are similar to our
previous research (Pavlovic et al., 2007)
Conclusion: The role of infection with criptosporidia in the occurrence of neonatal
enteropathies in piglets, because of the multiple agents, which cause this disease, has not been
fully explained, but our examination indicated that cryptosporidia might act, either in itself or
in concert with other agents to induce or exacerbate clinical disease.
PB  - Cluj-Napoca : University of Agricultural Sciences and Veterinary Medicine
C3  - The 22nd International conference ”Life sciences for sustainable development”, 28 - 30 September 2023, Cluj-Napoca, Romania
T1  - The role of protozoal infections in the cause of neonatal enteropathies of piglets
EP  - 317
SP  - 317
ER  - 

@conference{
author = "Pavlovic, Ivan and Savic, Bozidar and Zdravkovic, Nemanja and Radanovic, Oliver and Bojkovski, Jovan and Pavlovic, Marija and Tasic, Aleksandra",
year = "2023",
abstract = "Introduction: Neonatal enteropathies of piglets were recognized as a serious problem of the
modern pig industry. Today it is known that it is a multicausal disease caused by numerous
agents of bacterial, viral and parasitic etiology (Jacobson, 2022) The aim of our work is to
point out the importance of parasitic infections in this disease.
Materials and Methods: In period 2017-2020 a total of 337 pigs, 2-21 weeks old, were
exanimate. After routine necropsy, parasitological, bacteriological and viral evaluations were
performed, as required to establish the cause of disease in each pig. To parasitological
examination we used faecal swab, gut contents and a mucous scrape of gut which we
examined with Sheathers sugar flotation and in direct smears stained with Gimsa strain.
Results: During our examination Eimeria sp. were detected at two week old piglet at 4.22%,
Ispsora suis at 2-4 week old piglet at 12,34% and cryptosporidial organisms were detected in
the microvillus brush border in the intestine of the pigs ranged from 7-12 weeks old at
61,36%. Based on the time of onset of neonatal enteropathies, Cryptosporidium sp. was
confirmed as the main parasitic agent of its occurrence. These results are similar to our
previous research (Pavlovic et al., 2007)
Conclusion: The role of infection with criptosporidia in the occurrence of neonatal
enteropathies in piglets, because of the multiple agents, which cause this disease, has not been
fully explained, but our examination indicated that cryptosporidia might act, either in itself or
in concert with other agents to induce or exacerbate clinical disease.",
publisher = "Cluj-Napoca : University of Agricultural Sciences and Veterinary Medicine",
journal = "The 22nd International conference ”Life sciences for sustainable development”, 28 - 30 September 2023, Cluj-Napoca, Romania",
title = "The role of protozoal infections in the cause of neonatal enteropathies of piglets",
pages = "317-317"
}

Pavlovic, I., Savic, B., Zdravkovic, N., Radanovic, O., Bojkovski, J., Pavlovic, M.,& Tasic, A.. (2023). The role of protozoal infections in the cause of neonatal enteropathies of piglets. in The 22nd International conference ”Life sciences for sustainable development”, 28 - 30 September 2023, Cluj-Napoca, Romania
Cluj-Napoca : University of Agricultural Sciences and Veterinary Medicine., 317-317.

Pavlovic I, Savic B, Zdravkovic N, Radanovic O, Bojkovski J, Pavlovic M, Tasic A. The role of protozoal infections in the cause of neonatal enteropathies of piglets. in The 22nd International conference ”Life sciences for sustainable development”, 28 - 30 September 2023, Cluj-Napoca, Romania. 2023;:317-317..

Pavlovic, Ivan, Savic, Bozidar, Zdravkovic, Nemanja, Radanovic, Oliver, Bojkovski, Jovan, Pavlovic, Marija, Tasic, Aleksandra, "The role of protozoal infections in the cause of neonatal enteropathies of piglets" in The 22nd International conference ”Life sciences for sustainable development”, 28 - 30 September 2023, Cluj-Napoca, Romania (2023):317-317.

TY  - JOUR
AU  - Pavlović, Ivan
AU  - Stanojević, Slobodan
AU  - Zdravković, Nemanja
AU  - Radanović, Oliver
AU  - Bojkovski, Jovan
AU  - Janković, Ljiljana
AU  - Pavlović, Marija
AU  - Tasić, Aleksandra
AU  - Savić, Božidar
AU  - Vojinović, Dragica
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/828
AB  - Parasitic infections cause significant losses to swine production in the farm system. Aim of our work is to presented measures to control parasitic infections at farms breeding swine. The basic measures that were developed and applied were: 1. Use the principles of good production and hygiene practices, 2. Management of the production process, 3. Parasitological diagnostics 4. Application of antiparasitic drugs 5. Strict compliance with biosecurity measures 6. General animal hygiene measures 7. Pest control and disinfection 8. Control of stray dogs and cats on the farm and control of birds 9. Removal of corpses 10. Removal of waste 11. Educational program. The application of this integrated control concept of parasite infection required systematic monitoring of infection on farms and slaughterhouses before and after the applied measures. During the control before the application of the measures, then six months later, the results obtained showed a reduction in the prevalence of parasitic infections by over 80%. Certainly, the complexity of the problem required the involvement of all relevant entities, primarily veterinary services, from farms to slaughterhouses.
PB  - Medwin publishers
T2  - International Journal of Zoology and Animal Biology
T1  - Measure to control of parasitic infections of swine in commercial farm
IS  - 2
SP  - 000467
VL  - 6
DO  - 10.23880/izab-16000467
ER  - 

@article{
author = "Pavlović, Ivan and Stanojević, Slobodan and Zdravković, Nemanja and Radanović, Oliver and Bojkovski, Jovan and Janković, Ljiljana and Pavlović, Marija and Tasić, Aleksandra and Savić, Božidar and Vojinović, Dragica",
year = "2023",
abstract = "Parasitic infections cause significant losses to swine production in the farm system. Aim of our work is to presented measures to control parasitic infections at farms breeding swine. The basic measures that were developed and applied were: 1. Use the principles of good production and hygiene practices, 2. Management of the production process, 3. Parasitological diagnostics 4. Application of antiparasitic drugs 5. Strict compliance with biosecurity measures 6. General animal hygiene measures 7. Pest control and disinfection 8. Control of stray dogs and cats on the farm and control of birds 9. Removal of corpses 10. Removal of waste 11. Educational program. The application of this integrated control concept of parasite infection required systematic monitoring of infection on farms and slaughterhouses before and after the applied measures. During the control before the application of the measures, then six months later, the results obtained showed a reduction in the prevalence of parasitic infections by over 80%. Certainly, the complexity of the problem required the involvement of all relevant entities, primarily veterinary services, from farms to slaughterhouses.",
publisher = "Medwin publishers",
journal = "International Journal of Zoology and Animal Biology",
title = "Measure to control of parasitic infections of swine in commercial farm",
number = "2",
pages = "000467",
volume = "6",
doi = "10.23880/izab-16000467"
}

Pavlović, I., Stanojević, S., Zdravković, N., Radanović, O., Bojkovski, J., Janković, L., Pavlović, M., Tasić, A., Savić, B.,& Vojinović, D.. (2023). Measure to control of parasitic infections of swine in commercial farm. in International Journal of Zoology and Animal Biology
Medwin publishers., 6(2), 000467.
https://doi.org/10.23880/izab-16000467

Pavlović I, Stanojević S, Zdravković N, Radanović O, Bojkovski J, Janković L, Pavlović M, Tasić A, Savić B, Vojinović D. Measure to control of parasitic infections of swine in commercial farm. in International Journal of Zoology and Animal Biology. 2023;6(2):000467.
doi:10.23880/izab-16000467 .

Pavlović, Ivan, Stanojević, Slobodan, Zdravković, Nemanja, Radanović, Oliver, Bojkovski, Jovan, Janković, Ljiljana, Pavlović, Marija, Tasić, Aleksandra, Savić, Božidar, Vojinović, Dragica, "Measure to control of parasitic infections of swine in commercial farm" in International Journal of Zoology and Animal Biology, 6, no. 2 (2023):000467,
https://doi.org/10.23880/izab-16000467 . .

TY  - JOUR
AU  - Maksimović Zorić, Jelena
AU  - Veljović, Ljubiša
AU  - Radosavljević, Vladimir
AU  - Glišić, Dimitrije
AU  - Kureljušić, Jasna
AU  - Maletić, Jelena
AU  - Savić, Božidar
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/535
AB  - Swine influenza A viruses (swIAVs) are characterised by high mutation rates and zoonotic and pandemicpotential. In order to draw conclusions about virulence in swine and pathogenicity to humans, we examined the existenceof molecular markers and accessory proteins, cross-reactivity with vaccine strains, and resistance to antiviral drugs in five strainsof H1N1 swIAVs. Material and Methods: Amino acid (AA) sequences of five previously genetically characterised swIAVs wereanalysed in MEGA 7.0 software and the Influenza Research Database. Results: Amino acid analysis revealed three virus strainswith 590S/591R polymorphism and T271A substitution within basic polymerase 2 (PB2) AA chains, which cause enhanced virusreplication in mammalian cells. The other two strains possessed D701N and R251K substitutions within PB2 and synthesised PB1-F2protein, which are the factors of increased polymerase activity and virulence in swine. All strains synthesised PB1-N40, PA-N155,PA-N182, and PA-X proteins responsible for enhanced replication in mammalian cells and downregulation of the immune responseof the host. Mutations detected within haemagglutinin antigenic sites imply the antigenic drift of the five analysed viruses in relationto the vaccine strains. All viruses show susceptibility to neuraminidase inhibitors and baloxavir marboxil, which is important insituations of incidental human infections. Conclusion: The detection of virulence markers and accessory proteins in the analysedviruses suggests their higher propensity for replication in mammalian cells, increased virulence, and potential for transmission tohumans, and implies compromised efficacy of influenza vaccines.
PB  - Warsaw : Walter de Gruyter
T2  - Journal of Veterinary Research
T1  - Protein sequence featuresof H1N1 swine influenza A virusesdetected on commercial swine farms in Serbia
EP  - 154
IS  - 2
SP  - 147
VL  - 67
DO  - 10.2478/jvetres-2023-0034
ER  - 

@article{
author = "Maksimović Zorić, Jelena and Veljović, Ljubiša and Radosavljević, Vladimir and Glišić, Dimitrije and Kureljušić, Jasna and Maletić, Jelena and Savić, Božidar",
year = "2023",
abstract = "Swine influenza A viruses (swIAVs) are characterised by high mutation rates and zoonotic and pandemicpotential. In order to draw conclusions about virulence in swine and pathogenicity to humans, we examined the existenceof molecular markers and accessory proteins, cross-reactivity with vaccine strains, and resistance to antiviral drugs in five strainsof H1N1 swIAVs. Material and Methods: Amino acid (AA) sequences of five previously genetically characterised swIAVs wereanalysed in MEGA 7.0 software and the Influenza Research Database. Results: Amino acid analysis revealed three virus strainswith 590S/591R polymorphism and T271A substitution within basic polymerase 2 (PB2) AA chains, which cause enhanced virusreplication in mammalian cells. The other two strains possessed D701N and R251K substitutions within PB2 and synthesised PB1-F2protein, which are the factors of increased polymerase activity and virulence in swine. All strains synthesised PB1-N40, PA-N155,PA-N182, and PA-X proteins responsible for enhanced replication in mammalian cells and downregulation of the immune responseof the host. Mutations detected within haemagglutinin antigenic sites imply the antigenic drift of the five analysed viruses in relationto the vaccine strains. All viruses show susceptibility to neuraminidase inhibitors and baloxavir marboxil, which is important insituations of incidental human infections. Conclusion: The detection of virulence markers and accessory proteins in the analysedviruses suggests their higher propensity for replication in mammalian cells, increased virulence, and potential for transmission tohumans, and implies compromised efficacy of influenza vaccines.",
publisher = "Warsaw : Walter de Gruyter",
journal = "Journal of Veterinary Research",
title = "Protein sequence featuresof H1N1 swine influenza A virusesdetected on commercial swine farms in Serbia",
pages = "154-147",
number = "2",
volume = "67",
doi = "10.2478/jvetres-2023-0034"
}

Maksimović Zorić, J., Veljović, L., Radosavljević, V., Glišić, D., Kureljušić, J., Maletić, J.,& Savić, B.. (2023). Protein sequence featuresof H1N1 swine influenza A virusesdetected on commercial swine farms in Serbia. in Journal of Veterinary Research
Warsaw : Walter de Gruyter., 67(2), 147-154.
https://doi.org/10.2478/jvetres-2023-0034

Maksimović Zorić J, Veljović L, Radosavljević V, Glišić D, Kureljušić J, Maletić J, Savić B. Protein sequence featuresof H1N1 swine influenza A virusesdetected on commercial swine farms in Serbia. in Journal of Veterinary Research. 2023;67(2):147-154.
doi:10.2478/jvetres-2023-0034 .

Maksimović Zorić, Jelena, Veljović, Ljubiša, Radosavljević, Vladimir, Glišić, Dimitrije, Kureljušić, Jasna, Maletić, Jelena, Savić, Božidar, "Protein sequence featuresof H1N1 swine influenza A virusesdetected on commercial swine farms in Serbia" in Journal of Veterinary Research, 67, no. 2 (2023):147-154,
https://doi.org/10.2478/jvetres-2023-0034 . .

TY  - CONF
AU  - Zdravković, Nemanja
AU  - Radanović, Oliver
AU  - Stanojević, Slobodan
AU  - Ninković, Milan
AU  - Grujović, Isidora
AU  - Marjanović, Đorđe
AU  - Savić, Božidar
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/817
AB  - Pojava i prva izolacija etiološkog agensa svinjskog paratifusa: Salmonella
enterica subsp. enterica serovar Choleraesuis var. Kunzendorf u Srbiji uznemirava
opštu struĉnu javnost. Bolest je za sada izolovana kod domaćih svinja
koje se dovode u vezu sa uveţenim grlima, meĊutim epizootiološki znaĉaj ove
bolesti upućuje na divlje svinje. Populacija divljih svinja je ĉesto opisana kao
domaćin silvatiĉnog ciklusa kruţenja ove bakterije, a od 2022. godine izolovana
je u Švedskoj na severu Evrope.
Bakterija Salmonella Choleraesuis je fakultativno intracelularni patogen prilagoĊen
svinjama, ali je zabeleţen kod ljudi i predstavlja zoonotski agens.
Paratifus svinja se odlikuje sa kliniĉkim karakteristikama enterokolitisa i septikemije
ali su promene na plućima karakteristiĉne za ovaj serovar. Tokom 1950-
ih i 1960-ih, S. Choleraesuis je opisana kao dominantan serovar kod svinja
širom sveta i još uvek je veoma ĉest u Severnoj Americi i Aziji, a reĊe se otkriva
u Australiji i zapadnoj Evropi. Za nas je interesantno što su meĊu sluĉajevima
prijavljenim u Evropi izolati divljih svinja iz Rumunije. Uprkos niskoj prevalenciji
kod svinja i ogromnim problemima sa drugim infekcijama, S. Choleraesuis
postaje sve zastupljenija kod divljih svinja iz Evrope.
AB  - Finding and the first isolation of the etiological agent of swine paratyphoid:
Salmonella enterica subsp. Enterica serovar Choleraesuis var. Kunzendorf in
Serbia disturbed the animal protection professional public. For now, the
disease is isolated in domestic pigs, which are associated with imported
animals, however, the epizootiological importance of this disease points to wild
pigs. The population of wild boars in the Cental Europe is often described as
the host of the sylvatic circulation cycle of these bacteria, and since 2022 it has
been isolated in Sweden in the northern part of Europe.
Bacteria Salmonella Choleraesuis is a facultative intracellular pathogen adapted
to pigs, but has been reported in humans and is a zoonotic agent. Swine
paratyphoid is characterized by clinical features of enterocolitis and septicemia,
but lung changes are characteristic of this serovar. In the 1950s and
1960s, S. Choleraesuis was described as the dominant serovar in pigs worldwide
and is still very common in North America and Asia, and less commonly
detected in Australia and Western Europe. It is interesting for us that among the
cases reported in Europe are isolates from Romania. Despite its low prevalence
in pigs and huge problems with other infections, S. Choleraesuis is becoming
more prevalent in wild boars from Europe.
PB  - Beograd : Fakultet veterinarske medicine
C3  - Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023
T1  - Bolest koja dolazi – paratifus divljih svinja uzrokovan bakterijom Salmonella Choleresuis
T1  - The emerging disease wild boar paratyphoid caused by Salmonella Choleresuis
EP  - 304
SP  - 303
ER  - 

@conference{
author = "Zdravković, Nemanja and Radanović, Oliver and Stanojević, Slobodan and Ninković, Milan and Grujović, Isidora and Marjanović, Đorđe and Savić, Božidar",
year = "2023",
abstract = "Pojava i prva izolacija etiološkog agensa svinjskog paratifusa: Salmonella
enterica subsp. enterica serovar Choleraesuis var. Kunzendorf u Srbiji uznemirava
opštu struĉnu javnost. Bolest je za sada izolovana kod domaćih svinja
koje se dovode u vezu sa uveţenim grlima, meĊutim epizootiološki znaĉaj ove
bolesti upućuje na divlje svinje. Populacija divljih svinja je ĉesto opisana kao
domaćin silvatiĉnog ciklusa kruţenja ove bakterije, a od 2022. godine izolovana
je u Švedskoj na severu Evrope.
Bakterija Salmonella Choleraesuis je fakultativno intracelularni patogen prilagoĊen
svinjama, ali je zabeleţen kod ljudi i predstavlja zoonotski agens.
Paratifus svinja se odlikuje sa kliniĉkim karakteristikama enterokolitisa i septikemije
ali su promene na plućima karakteristiĉne za ovaj serovar. Tokom 1950-
ih i 1960-ih, S. Choleraesuis je opisana kao dominantan serovar kod svinja
širom sveta i još uvek je veoma ĉest u Severnoj Americi i Aziji, a reĊe se otkriva
u Australiji i zapadnoj Evropi. Za nas je interesantno što su meĊu sluĉajevima
prijavljenim u Evropi izolati divljih svinja iz Rumunije. Uprkos niskoj prevalenciji
kod svinja i ogromnim problemima sa drugim infekcijama, S. Choleraesuis
postaje sve zastupljenija kod divljih svinja iz Evrope., Finding and the first isolation of the etiological agent of swine paratyphoid:
Salmonella enterica subsp. Enterica serovar Choleraesuis var. Kunzendorf in
Serbia disturbed the animal protection professional public. For now, the
disease is isolated in domestic pigs, which are associated with imported
animals, however, the epizootiological importance of this disease points to wild
pigs. The population of wild boars in the Cental Europe is often described as
the host of the sylvatic circulation cycle of these bacteria, and since 2022 it has
been isolated in Sweden in the northern part of Europe.
Bacteria Salmonella Choleraesuis is a facultative intracellular pathogen adapted
to pigs, but has been reported in humans and is a zoonotic agent. Swine
paratyphoid is characterized by clinical features of enterocolitis and septicemia,
but lung changes are characteristic of this serovar. In the 1950s and
1960s, S. Choleraesuis was described as the dominant serovar in pigs worldwide
and is still very common in North America and Asia, and less commonly
detected in Australia and Western Europe. It is interesting for us that among the
cases reported in Europe are isolates from Romania. Despite its low prevalence
in pigs and huge problems with other infections, S. Choleraesuis is becoming
more prevalent in wild boars from Europe.",
publisher = "Beograd : Fakultet veterinarske medicine",
journal = "Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023",
title = "Bolest koja dolazi – paratifus divljih svinja uzrokovan bakterijom Salmonella Choleresuis, The emerging disease wild boar paratyphoid caused by Salmonella Choleresuis",
pages = "304-303"
}

Zdravković, N., Radanović, O., Stanojević, S., Ninković, M., Grujović, I., Marjanović, Đ.,& Savić, B.. (2023). Bolest koja dolazi – paratifus divljih svinja uzrokovan bakterijom Salmonella Choleresuis. in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023
Beograd : Fakultet veterinarske medicine., 303-304.

Zdravković N, Radanović O, Stanojević S, Ninković M, Grujović I, Marjanović Đ, Savić B. Bolest koja dolazi – paratifus divljih svinja uzrokovan bakterijom Salmonella Choleresuis. in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023. 2023;:303-304..

Zdravković, Nemanja, Radanović, Oliver, Stanojević, Slobodan, Ninković, Milan, Grujović, Isidora, Marjanović, Đorđe, Savić, Božidar, "Bolest koja dolazi – paratifus divljih svinja uzrokovan bakterijom Salmonella Choleresuis" in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023 (2023):303-304.

TY  - CONF
AU  - Milovanović, Bojan
AU  - Stanojević, Slobodan
AU  - Kureljušić, Branislav
AU  - Zurovac Sapundžić, Zorana
AU  - Milićević, Vesna
AU  - Zdravković, Nemanja
AU  - Jezdimirović, Nemanja
AU  - Maletić, Milan
AU  - Savić, Božidar
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/816
AB  - Pojava povremenih pobačaja ne predstavlja razlog za zabrinutost. Dva glavna
kriterijuma kada pojava pobačaja postaje problem u zapatu su: ako stopa
pobačaja pređe 3% na 100 steonih krava ili 5% na 100 jagnjenih ovaca, ili
ukoliko veći broj životinja pobaci u kratkom vremenskom intervalu. U bilo koja
dva navedena slučaja neophodno je obavestiti ordinirajućeg veterinara i nadležnog
veterinarskog inspektora. Pobačaji se mogu podeliti na infektivne i neinfektivne.
Pobačaje infektivne prirode uzrokuju različiti virusi, bakterije (Brucella
abortus, Brucella ovis, Chlamydia abortus), gljivice, protozoe (Neospora
caninum) i rikecije (Coxiella burnetii). Uzročnici neinfektivne prirode mogu
biti: otrovne biljke, metabolički i hormonalni poremećaji, nutritivni deficiti,
traume i kongenitalne anomalije ploda. Etiološka dijagnoza pobačaja postavlja
se u svega 30% slučajeva – kod 40 do 50% slučajeva nije moguće utvrditi
uzrok. Podaci o zastupljenosti infektivnih agenasa kao uzročnika pobačaja variraju
u zavisnosti od regiona, načina držanja i uzoraka koji se dostavljaju na
laboratorijsko ispitivanje. Pored direktnog uticaja na zdravlje i dobrobit životinja,
pobačaji dovode i do ekonomskih gubitaka. Pojedini infektivni uzročnici
imaju zoonotski potencijal i predstavljaju opasnost po javno zdravlje. Zbog toga
prevencija pobačaja predstavlja imperativ u procesu proizvodnje.
AB  - The occurrence of periodical abortions is not a reason for concern. Two main
criteria when the abortions represent a problem on farm are: abortion rate
exceeds 3% per 100 pregnant cows or 5% per 100 pregnant ewes; certain
number of animals abort in a short time interval (abortion storm). In many of
two mentioned cases, it is necessary to inform the ordinating veterinarian and
the regional veterinary inspector. Etiology of abortions can be divided into
infectious and noninfectious. Infectious causes of abortions are viruses, bacteria
(Brucella abortus, Brucella ovis, Chlamydia abortus), fungi, protozoan (Neospora
caninum), rickettsias (Coxiella burnetii). Noninfectious abortions can be
caused by: heat stress, poisonous plants, metabolic and hormonal disorders,
nutritional deficits, trauma and congenital anomalies of fetus. The etiological
diagnosis of abortions is determinated in 30% of cases. In 40 to 50% of cases,
depending on the available laboratory diagnostics, it is not possible to establish
the cause. Data about prevalence of infectious agents vary depending on the
region, management and the samples that were submitted to diagnostic laboratory.
A spite of direct influence on animal health and welfare, abortions lead
to economic losses. Some infectious agents have zoonotic potential and represent
a risk to public health. Therefore, abortion control represent imperative in
the production process.
PB  - Beograd : Fakultet veterinarske medicine
C3  - Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023
T1  - Infektivni pobačaji preživara – zdravstveni i ekonomski značaj
T1  - Infectious abortions in ruminants–health and economic impact
EP  - 215
SP  - 207
ER  - 

@conference{
author = "Milovanović, Bojan and Stanojević, Slobodan and Kureljušić, Branislav and Zurovac Sapundžić, Zorana and Milićević, Vesna and Zdravković, Nemanja and Jezdimirović, Nemanja and Maletić, Milan and Savić, Božidar",
year = "2023",
abstract = "Pojava povremenih pobačaja ne predstavlja razlog za zabrinutost. Dva glavna
kriterijuma kada pojava pobačaja postaje problem u zapatu su: ako stopa
pobačaja pređe 3% na 100 steonih krava ili 5% na 100 jagnjenih ovaca, ili
ukoliko veći broj životinja pobaci u kratkom vremenskom intervalu. U bilo koja
dva navedena slučaja neophodno je obavestiti ordinirajućeg veterinara i nadležnog
veterinarskog inspektora. Pobačaji se mogu podeliti na infektivne i neinfektivne.
Pobačaje infektivne prirode uzrokuju različiti virusi, bakterije (Brucella
abortus, Brucella ovis, Chlamydia abortus), gljivice, protozoe (Neospora
caninum) i rikecije (Coxiella burnetii). Uzročnici neinfektivne prirode mogu
biti: otrovne biljke, metabolički i hormonalni poremećaji, nutritivni deficiti,
traume i kongenitalne anomalije ploda. Etiološka dijagnoza pobačaja postavlja
se u svega 30% slučajeva – kod 40 do 50% slučajeva nije moguće utvrditi
uzrok. Podaci o zastupljenosti infektivnih agenasa kao uzročnika pobačaja variraju
u zavisnosti od regiona, načina držanja i uzoraka koji se dostavljaju na
laboratorijsko ispitivanje. Pored direktnog uticaja na zdravlje i dobrobit životinja,
pobačaji dovode i do ekonomskih gubitaka. Pojedini infektivni uzročnici
imaju zoonotski potencijal i predstavljaju opasnost po javno zdravlje. Zbog toga
prevencija pobačaja predstavlja imperativ u procesu proizvodnje., The occurrence of periodical abortions is not a reason for concern. Two main
criteria when the abortions represent a problem on farm are: abortion rate
exceeds 3% per 100 pregnant cows or 5% per 100 pregnant ewes; certain
number of animals abort in a short time interval (abortion storm). In many of
two mentioned cases, it is necessary to inform the ordinating veterinarian and
the regional veterinary inspector. Etiology of abortions can be divided into
infectious and noninfectious. Infectious causes of abortions are viruses, bacteria
(Brucella abortus, Brucella ovis, Chlamydia abortus), fungi, protozoan (Neospora
caninum), rickettsias (Coxiella burnetii). Noninfectious abortions can be
caused by: heat stress, poisonous plants, metabolic and hormonal disorders,
nutritional deficits, trauma and congenital anomalies of fetus. The etiological
diagnosis of abortions is determinated in 30% of cases. In 40 to 50% of cases,
depending on the available laboratory diagnostics, it is not possible to establish
the cause. Data about prevalence of infectious agents vary depending on the
region, management and the samples that were submitted to diagnostic laboratory.
A spite of direct influence on animal health and welfare, abortions lead
to economic losses. Some infectious agents have zoonotic potential and represent
a risk to public health. Therefore, abortion control represent imperative in
the production process.",
publisher = "Beograd : Fakultet veterinarske medicine",
journal = "Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023",
title = "Infektivni pobačaji preživara – zdravstveni i ekonomski značaj, Infectious abortions in ruminants–health and economic impact",
pages = "215-207"
}

Milovanović, B., Stanojević, S., Kureljušić, B., Zurovac Sapundžić, Z., Milićević, V., Zdravković, N., Jezdimirović, N., Maletić, M.,& Savić, B.. (2023). Infektivni pobačaji preživara – zdravstveni i ekonomski značaj. in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023
Beograd : Fakultet veterinarske medicine., 207-215.

Milovanović B, Stanojević S, Kureljušić B, Zurovac Sapundžić Z, Milićević V, Zdravković N, Jezdimirović N, Maletić M, Savić B. Infektivni pobačaji preživara – zdravstveni i ekonomski značaj. in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023. 2023;:207-215..

Milovanović, Bojan, Stanojević, Slobodan, Kureljušić, Branislav, Zurovac Sapundžić, Zorana, Milićević, Vesna, Zdravković, Nemanja, Jezdimirović, Nemanja, Maletić, Milan, Savić, Božidar, "Infektivni pobačaji preživara – zdravstveni i ekonomski značaj" in Četvrti regionalni simpozijum Zaštita agrobiodiverziteta i očuvanje autohtonih rasa domaćih životinja, Dimitrovgrad, 29. jun - 1. jul 2023 (2023):207-215.

TY  - CONF
AU  - Savić, Božidar
AU  - Kureljušić, Branislav
AU  - Milićević, Vesna
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Zdravković, Nemanja
AU  - Stevančević, Dimitrije
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/802
AB  - Porcine reproductive and respiratory syndrome virus CPRRSV) is the causative agent of a devastating pig disease worldwide, which is endemic in many countries, including the Serbia. Only limited epidemiological or molecular studies has been published on circulating PRRS-viruses in the Serbia since the early nineties. Therefore, the aim of this study is to investigate the genetic diversity of circulating PRRS-viruses in Serbia in the last ten years, by comparing the nucleotid€ sequences obtained for ORF5, wlth the ORF5 sequences of PRRSV 1 subtype 1.
PB  - ECPHM
C3  - Proceedings : ESPHM : 14th European symposium of porcine health management
T1  - Genetic diversity of the orf5 gene of type 1 porcine reproductive and respiratory syndrome virus isolates in Serbian swine herds from 2012 to 2022
EP  - 323
SP  - 323
ER  - 

@conference{
author = "Savić, Božidar and Kureljušić, Branislav and Milićević, Vesna and Jezdimirović, Nemanja and Milovanović, Bojan and Zdravković, Nemanja and Stevančević, Dimitrije",
year = "2023",
abstract = "Porcine reproductive and respiratory syndrome virus CPRRSV) is the causative agent of a devastating pig disease worldwide, which is endemic in many countries, including the Serbia. Only limited epidemiological or molecular studies has been published on circulating PRRS-viruses in the Serbia since the early nineties. Therefore, the aim of this study is to investigate the genetic diversity of circulating PRRS-viruses in Serbia in the last ten years, by comparing the nucleotid€ sequences obtained for ORF5, wlth the ORF5 sequences of PRRSV 1 subtype 1.",
publisher = "ECPHM",
journal = "Proceedings : ESPHM : 14th European symposium of porcine health management",
title = "Genetic diversity of the orf5 gene of type 1 porcine reproductive and respiratory syndrome virus isolates in Serbian swine herds from 2012 to 2022",
pages = "323-323"
}

Savić, B., Kureljušić, B., Milićević, V., Jezdimirović, N., Milovanović, B., Zdravković, N.,& Stevančević, D.. (2023). Genetic diversity of the orf5 gene of type 1 porcine reproductive and respiratory syndrome virus isolates in Serbian swine herds from 2012 to 2022. in Proceedings : ESPHM : 14th European symposium of porcine health management
ECPHM., 323-323.

Savić B, Kureljušić B, Milićević V, Jezdimirović N, Milovanović B, Zdravković N, Stevančević D. Genetic diversity of the orf5 gene of type 1 porcine reproductive and respiratory syndrome virus isolates in Serbian swine herds from 2012 to 2022. in Proceedings : ESPHM : 14th European symposium of porcine health management. 2023;:323-323..

Savić, Božidar, Kureljušić, Branislav, Milićević, Vesna, Jezdimirović, Nemanja, Milovanović, Bojan, Zdravković, Nemanja, Stevančević, Dimitrije, "Genetic diversity of the orf5 gene of type 1 porcine reproductive and respiratory syndrome virus isolates in Serbian swine herds from 2012 to 2022" in Proceedings : ESPHM : 14th European symposium of porcine health management (2023):323-323.

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Milićević, Vesna
AU  - Milovanović, Bojan
AU  - Glišić, Dimitrije
AU  - Maletić, Jelena
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Jasna
AU  - Prodanov Radulović, Jasna
AU  - Savić, Božidar
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/804
AB  - Biosecurity ls of paramount Importance to prevent the introduction and spread of pathogens in pig farms. Applied biosecurity measures and efficient on-farm management protect pigs from different infectious diseases. African swine fever CASF) is a severe, viral disease of domestic pigs and wild boar. After the occurrence in 2007 in Georgia, the disease gradually spread throughout Europe. The first case of ASF in Serbia was confirmed on July 30, 2019.
PB  - ECPHM
C3  - Proceedings : ESPHM : 14th European symposium of porcine health management
T1  - Assessment of biosecurity measures in the Serbian backyards where the first African swine fever cases were confirmed
EP  - 253
SP  - 253
ER  - 

@conference{
author = "Kureljušić, Branislav and Milićević, Vesna and Milovanović, Bojan and Glišić, Dimitrije and Maletić, Jelena and Jezdimirović, Nemanja and Kureljušić, Jasna and Prodanov Radulović, Jasna and Savić, Božidar",
year = "2023",
abstract = "Biosecurity ls of paramount Importance to prevent the introduction and spread of pathogens in pig farms. Applied biosecurity measures and efficient on-farm management protect pigs from different infectious diseases. African swine fever CASF) is a severe, viral disease of domestic pigs and wild boar. After the occurrence in 2007 in Georgia, the disease gradually spread throughout Europe. The first case of ASF in Serbia was confirmed on July 30, 2019.",
publisher = "ECPHM",
journal = "Proceedings : ESPHM : 14th European symposium of porcine health management",
title = "Assessment of biosecurity measures in the Serbian backyards where the first African swine fever cases were confirmed",
pages = "253-253"
}

Kureljušić, B., Milićević, V., Milovanović, B., Glišić, D., Maletić, J., Jezdimirović, N., Kureljušić, J., Prodanov Radulović, J.,& Savić, B.. (2023). Assessment of biosecurity measures in the Serbian backyards where the first African swine fever cases were confirmed. in Proceedings : ESPHM : 14th European symposium of porcine health management
ECPHM., 253-253.

Kureljušić B, Milićević V, Milovanović B, Glišić D, Maletić J, Jezdimirović N, Kureljušić J, Prodanov Radulović J, Savić B. Assessment of biosecurity measures in the Serbian backyards where the first African swine fever cases were confirmed. in Proceedings : ESPHM : 14th European symposium of porcine health management. 2023;:253-253..

Kureljušić, Branislav, Milićević, Vesna, Milovanović, Bojan, Glišić, Dimitrije, Maletić, Jelena, Jezdimirović, Nemanja, Kureljušić, Jasna, Prodanov Radulović, Jasna, Savić, Božidar, "Assessment of biosecurity measures in the Serbian backyards where the first African swine fever cases were confirmed" in Proceedings : ESPHM : 14th European symposium of porcine health management (2023):253-253.

TY  - CONF
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Branislav
AU  - Savić, Božidar
AU  - Milovanović, Bojan
AU  - Glišić, Dimitrije
AU  - Maksimović Zorić, Jelena
AU  - Milićević, Vesna
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/767
AB  - Kliničko oboljenje uzrokovano sa porcine citomegalovirus (PCMV) se javlja samo
kod svinja, iako se infekcije srodnim virusima pojavljuju i kod drugih životinjskih vrsta
uključujući i ljude. Citomegalovirus kod svinja uzrokuje rinitis sa inkluzionim
telašcima (IBR), PCMV pripada podfamiliji Betaherpesvirinae i familiji Herpesviridae,
ali nije svrstan ni u jedan rod, a genetska istraživanja su pokazala da je PCMV genetski
srodniji humanim herpes virusima 6 i 7. Infekcija sa PCMV je prisutna širom sveta,
dominantno u zemljama sa intenzivnom proizvodnjom svinja i uglavnom je klinički
inaparentna zbog stečenog imuniteta zapata. Virus se prenosi horizontalno
(oronazalnim putem), a moguća je i kongenitalna transmisija, pa inficirani fetusi mogu
biti, mumificirani, mrtvorođeni ili rođeni živi kao slabo vitalna prasad. Kliničko
oboljenje se pojavljuje u akutnoj ili subakutnoj formi kod prasadi starosti do 4 nedelje,
a može se pojaviti i kod drugih starosnih kategorija u neimunim zapatima. Svinje koje
su prebolele infekciju ostaju doživotne kliconoše. Suide predstavljaju jedini rezervoar
virusa u prirodi. Rinitis sa inkluzionim telašcima je visoko prevalentna infekcija i
pretpostavlja se da je prevalencija oboljenja preko 90% na globalnom nivou, odnosno
98% u Evropi. U našoj zemlji još uvek nisu rađena opsežna istraživanja na utvrđivanju
prevalence oboljenja zbog čega su prevalenca infekcije i incidenca oboljenja još uvek
nepoznate. Zbog cirkulacije drugih respiratornih virusa u farmskim uslovima uzgoja
svinja, PCMV je često zapostavljen. Na poziv veterinarske službe, na farmi koja je imala učestale probleme sa
respiratornim oboljenjima, izvršili smo uzorkovanje oralnog fluida i analizirali
prikupljene uzorke primenom lančane reakcije polimeraze na prisustvo sledećih
virusnih agenasa: Encephalomyocarditis virus (EMCV), PCMV, Porcine circovirus tip 2
(PCV2). Virus reproduktivnog i respiratornog sindroma svinja (PRRSV) i Virus
influence svinja (SIV), sa ciljem uvida u prisustvo virusnih infektivnih agenasa na
farmi. Izvršenim analizama smo pored detekcije PRRSV, PCV2 i SIV, ustanovili i
prisustvo genoma PCMV kod prasadi iz odgoja. Mortalitet prasadi u neimunim
zapatima od posledica kliničkog PCMV-rinitisa može dostići 10%, ali se može povećati
do čak 50% ukoliko se bolest komplikuje drugim virusnim ili bakterijskim infekcijama.
Klinički značaj prisustva PCMV u konkretnom slučaju bi trebalo razmatrati u
kontekstu detekcije drugih virusnih patogena i njihovog sinergističkog efekta.
Međutim, obzirom da PCMV samostalno ili u koinfekcijama sa drugim, pre svega
virusnim respiratornim agensima može biti uzrok povećanja mortaliteta, ne treba ga
zanemariti. Vakcina protiv PCMV i specifična terapija ovog oboljenja ne postoje, sa
druge strane, ne postojanje informacija o prevalenci PCMV u našoj zemlji kao ni
vršenje rutinskog pregleda na ovu infekciju, predstavlja značajan rizik za širenje
virusa pre svega uvođenjem novonabavljenih životinja u zapat.
PB  - Beograd : Srpsko veterinarsko društvo
C3  - 34. Savetovanje veterinara Srbije, Zlatibor,  7-10. septembar 2023
T1  - Prva molekularna detekcija citomegalovirusa svinja u Srbiji
EP  - 95
SP  - 90
ER  - 

@conference{
author = "Jezdimirović, Nemanja and Kureljušić, Branislav and Savić, Božidar and Milovanović, Bojan and Glišić, Dimitrije and Maksimović Zorić, Jelena and Milićević, Vesna",
year = "2023",
abstract = "Kliničko oboljenje uzrokovano sa porcine citomegalovirus (PCMV) se javlja samo
kod svinja, iako se infekcije srodnim virusima pojavljuju i kod drugih životinjskih vrsta
uključujući i ljude. Citomegalovirus kod svinja uzrokuje rinitis sa inkluzionim
telašcima (IBR), PCMV pripada podfamiliji Betaherpesvirinae i familiji Herpesviridae,
ali nije svrstan ni u jedan rod, a genetska istraživanja su pokazala da je PCMV genetski
srodniji humanim herpes virusima 6 i 7. Infekcija sa PCMV je prisutna širom sveta,
dominantno u zemljama sa intenzivnom proizvodnjom svinja i uglavnom je klinički
inaparentna zbog stečenog imuniteta zapata. Virus se prenosi horizontalno
(oronazalnim putem), a moguća je i kongenitalna transmisija, pa inficirani fetusi mogu
biti, mumificirani, mrtvorođeni ili rođeni živi kao slabo vitalna prasad. Kliničko
oboljenje se pojavljuje u akutnoj ili subakutnoj formi kod prasadi starosti do 4 nedelje,
a može se pojaviti i kod drugih starosnih kategorija u neimunim zapatima. Svinje koje
su prebolele infekciju ostaju doživotne kliconoše. Suide predstavljaju jedini rezervoar
virusa u prirodi. Rinitis sa inkluzionim telašcima je visoko prevalentna infekcija i
pretpostavlja se da je prevalencija oboljenja preko 90% na globalnom nivou, odnosno
98% u Evropi. U našoj zemlji još uvek nisu rađena opsežna istraživanja na utvrđivanju
prevalence oboljenja zbog čega su prevalenca infekcije i incidenca oboljenja još uvek
nepoznate. Zbog cirkulacije drugih respiratornih virusa u farmskim uslovima uzgoja
svinja, PCMV je često zapostavljen. Na poziv veterinarske službe, na farmi koja je imala učestale probleme sa
respiratornim oboljenjima, izvršili smo uzorkovanje oralnog fluida i analizirali
prikupljene uzorke primenom lančane reakcije polimeraze na prisustvo sledećih
virusnih agenasa: Encephalomyocarditis virus (EMCV), PCMV, Porcine circovirus tip 2
(PCV2). Virus reproduktivnog i respiratornog sindroma svinja (PRRSV) i Virus
influence svinja (SIV), sa ciljem uvida u prisustvo virusnih infektivnih agenasa na
farmi. Izvršenim analizama smo pored detekcije PRRSV, PCV2 i SIV, ustanovili i
prisustvo genoma PCMV kod prasadi iz odgoja. Mortalitet prasadi u neimunim
zapatima od posledica kliničkog PCMV-rinitisa može dostići 10%, ali se može povećati
do čak 50% ukoliko se bolest komplikuje drugim virusnim ili bakterijskim infekcijama.
Klinički značaj prisustva PCMV u konkretnom slučaju bi trebalo razmatrati u
kontekstu detekcije drugih virusnih patogena i njihovog sinergističkog efekta.
Međutim, obzirom da PCMV samostalno ili u koinfekcijama sa drugim, pre svega
virusnim respiratornim agensima može biti uzrok povećanja mortaliteta, ne treba ga
zanemariti. Vakcina protiv PCMV i specifična terapija ovog oboljenja ne postoje, sa
druge strane, ne postojanje informacija o prevalenci PCMV u našoj zemlji kao ni
vršenje rutinskog pregleda na ovu infekciju, predstavlja značajan rizik za širenje
virusa pre svega uvođenjem novonabavljenih životinja u zapat.",
publisher = "Beograd : Srpsko veterinarsko društvo",
journal = "34. Savetovanje veterinara Srbije, Zlatibor,  7-10. septembar 2023",
title = "Prva molekularna detekcija citomegalovirusa svinja u Srbiji",
pages = "95-90"
}

Jezdimirović, N., Kureljušić, B., Savić, B., Milovanović, B., Glišić, D., Maksimović Zorić, J.,& Milićević, V.. (2023). Prva molekularna detekcija citomegalovirusa svinja u Srbiji. in 34. Savetovanje veterinara Srbije, Zlatibor,  7-10. septembar 2023
Beograd : Srpsko veterinarsko društvo., 90-95.

Jezdimirović N, Kureljušić B, Savić B, Milovanović B, Glišić D, Maksimović Zorić J, Milićević V. Prva molekularna detekcija citomegalovirusa svinja u Srbiji. in 34. Savetovanje veterinara Srbije, Zlatibor,  7-10. septembar 2023. 2023;:90-95..

Jezdimirović, Nemanja, Kureljušić, Branislav, Savić, Božidar, Milovanović, Bojan, Glišić, Dimitrije, Maksimović Zorić, Jelena, Milićević, Vesna, "Prva molekularna detekcija citomegalovirusa svinja u Srbiji" in 34. Savetovanje veterinara Srbije, Zlatibor,  7-10. septembar 2023 (2023):90-95.

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Savić, Božidar
AU  - Milovanović, Bojan
AU  - Maletić, Jelena
AU  - Ninković, Milan
AU  - Jezdimirović, Nemanja
AU  - Prodanov Radulović, Jasna
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/686
AB  - Biosecurity measures together with the efficient on-farm management embraces all aspects of
the prevention of pathogens entering pig farms, regardless of structure and animal number. In
the present study assessment of biosecurity measures in the commercial (industrial) pig farms in
Serbia was carried out through application of the questionnaire to farm veterinarians.
To assess biosecurity in commercial (industrial) farms, a Biocheck online survey
(https://biocheckgent.com) was conducted in the ten commercial pigs farms located in the
Northern part of Serbia where industrial pig production is localized and the highest density of pig
production can be found.
The results of the external biosecurity assessment showed a mean score of 75.55%, compared to
the average in Serbia, which was 68.55%, and the global average of 73%. External biosecurity
assessment showed the lowest scores for feed, water and equipment supply (47%). The
assessment of internal biosecurity revealed a score of 54.89% compared to the national average
of 44.22% and the world average of 64.11%. Regarding internal biosecurity, the lowest
percentage score (37.22%) was confirmed for farrowing and suckling period and for finishing unit
(37.67%). The overall biosecurity score for commercial pig farms included in this study was
65.55%. The national average was 56.33%, while the global average was 68.67%.
This study showed a bit less lower level of biosecurity measures in commercial pig farms in Serbia
comparing with global average. Certainly, having in mind the different pig production systems in
Serbia, there is urgent need to improve biosecurity in industrial farms. Serbia as a Western Balkan
country, has variable pig farming system characterized by a domination of traditional family
farms, smallholdings, backyard production and semi-free and free-range. Currently, traditional
farming methods in Serbia represent a cultural identity. The biosecurity measures that could be
implemented in extisted animal production systems need to be urgently identified.
PB  - Ghent : Faculty of veterinary medicine
C3  - COST action CA20103 "Biosecurity Enhanced Through Training Evaluation and Raising Awareness"
T1  - Assessment of biosecurity measures in the commercial (industrial) pig farms in Serbia
EP  - 39
SP  - 39
ER  - 

@conference{
author = "Kureljušić, Branislav and Savić, Božidar and Milovanović, Bojan and Maletić, Jelena and Ninković, Milan and Jezdimirović, Nemanja and Prodanov Radulović, Jasna",
year = "2023",
abstract = "Biosecurity measures together with the efficient on-farm management embraces all aspects of
the prevention of pathogens entering pig farms, regardless of structure and animal number. In
the present study assessment of biosecurity measures in the commercial (industrial) pig farms in
Serbia was carried out through application of the questionnaire to farm veterinarians.
To assess biosecurity in commercial (industrial) farms, a Biocheck online survey
(https://biocheckgent.com) was conducted in the ten commercial pigs farms located in the
Northern part of Serbia where industrial pig production is localized and the highest density of pig
production can be found.
The results of the external biosecurity assessment showed a mean score of 75.55%, compared to
the average in Serbia, which was 68.55%, and the global average of 73%. External biosecurity
assessment showed the lowest scores for feed, water and equipment supply (47%). The
assessment of internal biosecurity revealed a score of 54.89% compared to the national average
of 44.22% and the world average of 64.11%. Regarding internal biosecurity, the lowest
percentage score (37.22%) was confirmed for farrowing and suckling period and for finishing unit
(37.67%). The overall biosecurity score for commercial pig farms included in this study was
65.55%. The national average was 56.33%, while the global average was 68.67%.
This study showed a bit less lower level of biosecurity measures in commercial pig farms in Serbia
comparing with global average. Certainly, having in mind the different pig production systems in
Serbia, there is urgent need to improve biosecurity in industrial farms. Serbia as a Western Balkan
country, has variable pig farming system characterized by a domination of traditional family
farms, smallholdings, backyard production and semi-free and free-range. Currently, traditional
farming methods in Serbia represent a cultural identity. The biosecurity measures that could be
implemented in extisted animal production systems need to be urgently identified.",
publisher = "Ghent : Faculty of veterinary medicine",
journal = "COST action CA20103 "Biosecurity Enhanced Through Training Evaluation and Raising Awareness"",
title = "Assessment of biosecurity measures in the commercial (industrial) pig farms in Serbia",
pages = "39-39"
}

Kureljušić, B., Savić, B., Milovanović, B., Maletić, J., Ninković, M., Jezdimirović, N.,& Prodanov Radulović, J.. (2023). Assessment of biosecurity measures in the commercial (industrial) pig farms in Serbia. in COST action CA20103 "Biosecurity Enhanced Through Training Evaluation and Raising Awareness"
Ghent : Faculty of veterinary medicine., 39-39.

Kureljušić B, Savić B, Milovanović B, Maletić J, Ninković M, Jezdimirović N, Prodanov Radulović J. Assessment of biosecurity measures in the commercial (industrial) pig farms in Serbia. in COST action CA20103 "Biosecurity Enhanced Through Training Evaluation and Raising Awareness". 2023;:39-39..

Kureljušić, Branislav, Savić, Božidar, Milovanović, Bojan, Maletić, Jelena, Ninković, Milan, Jezdimirović, Nemanja, Prodanov Radulović, Jasna, "Assessment of biosecurity measures in the commercial (industrial) pig farms in Serbia" in COST action CA20103 "Biosecurity Enhanced Through Training Evaluation and Raising Awareness" (2023):39-39.

TY  - CONF
AU  - Maksimović Zorić, Jelena
AU  - Veljović, Ljubiša
AU  - Glišić, Dimitrije
AU  - Jezdimirović, Nemanja
AU  - Savić, Božidar
AU  - Milovanović, Bojan
AU  - Maletić, Jelena
AU  - Radosavljević, Vladimir
AU  - Kureljušić, Branislav
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/652
AB  - Swine influenza is a worldwide present respiratory disease of swine, in majority of cases caused by H1N1,
H1N2, and H3N2 subtypes of swine influenza A virus (swIAV). Exploration of the swIAV in Serbia in recent
ten years mainly was oriented to the passive surveillance and examination within PRDC on commercial pig
farms. The latest results suggest circulation of the viruses in the majority of the analysed commercial farms
and the presence of two subtypes - H1N1 and H3N2. Even though the problem exists none of the farms
apply vaccination as a measure of disease control. The aim of this research is to analyse the results of
passive surveillance on the two commercial farms conducted from 2020th to 2022nd.
A total of 94 samples for molecular analyses and 528 samples for serological analyses were submitted to
the Institute of Veterinary Medicine of Serbia during this period. These samples were obtained from swine
raised in two commercial farms (farm A and farm B) that practice farrow-to-finish production and have
implemented satisfactory biosecurity measures. The samples for molecular examination were mummified
fetuses, nasal swabs, oral fluids, parenchymatous organs, lungs, and sera. All samples were tested by M
gene real-time RT-PCR, according to the accredited WHO protocol (2009) for detection of influenza A
viruses. One virus was typed using multiplex real-time RT-PCR protocols described by Henritzi et al. (2016).
Serological examination was conducted using ELISA test (Ingezim Influenza A Kit, Ingenasa), and tested sera
originated from sows, suckling piglets, and nursing pigs.
During three year period influenza A viruses were detected on both farms, having on average 55,3% of the
analyzed samples positive. The highest detection rate was amongst the nasal swab (78.7%) and oral fluid
samples (83.3%), while virus was not confirmed in mummified fetuses and sera. Most of the samples
analyzed by PCR originated from farm A (80 samples), and the majority of tested were positive (60%).
Molecular typing revealed presence of H1N1 subtype in farm A that is in accordance with previous results
that confirmed H1N1 as dominating subtype that circulates in commercial farms in Serbia. Serology
examination confirmed a high overall seroprevalence of 64,6%. The serum samples from nursing pigs
accounted for the highest proportion (95.4%) among those examined, as respiratory issues linked to PRDC
typically manifest in this group. Given the endemic presence of swIAVs in the farms under analysis, there is
a pressing need to conduct further research on the circulating viruses and enhance the control measures
employed on these farms.
PB  - ESFLU
C3  - ESFLU Scientific meeting, Barcelona, 25-27th April 2023
T1  - Serological and molecular investigation of influenza in commercial pig farms in Serbia
ER  - 

@conference{
author = "Maksimović Zorić, Jelena and Veljović, Ljubiša and Glišić, Dimitrije and Jezdimirović, Nemanja and Savić, Božidar and Milovanović, Bojan and Maletić, Jelena and Radosavljević, Vladimir and Kureljušić, Branislav",
year = "2023",
abstract = "Swine influenza is a worldwide present respiratory disease of swine, in majority of cases caused by H1N1,
H1N2, and H3N2 subtypes of swine influenza A virus (swIAV). Exploration of the swIAV in Serbia in recent
ten years mainly was oriented to the passive surveillance and examination within PRDC on commercial pig
farms. The latest results suggest circulation of the viruses in the majority of the analysed commercial farms
and the presence of two subtypes - H1N1 and H3N2. Even though the problem exists none of the farms
apply vaccination as a measure of disease control. The aim of this research is to analyse the results of
passive surveillance on the two commercial farms conducted from 2020th to 2022nd.
A total of 94 samples for molecular analyses and 528 samples for serological analyses were submitted to
the Institute of Veterinary Medicine of Serbia during this period. These samples were obtained from swine
raised in two commercial farms (farm A and farm B) that practice farrow-to-finish production and have
implemented satisfactory biosecurity measures. The samples for molecular examination were mummified
fetuses, nasal swabs, oral fluids, parenchymatous organs, lungs, and sera. All samples were tested by M
gene real-time RT-PCR, according to the accredited WHO protocol (2009) for detection of influenza A
viruses. One virus was typed using multiplex real-time RT-PCR protocols described by Henritzi et al. (2016).
Serological examination was conducted using ELISA test (Ingezim Influenza A Kit, Ingenasa), and tested sera
originated from sows, suckling piglets, and nursing pigs.
During three year period influenza A viruses were detected on both farms, having on average 55,3% of the
analyzed samples positive. The highest detection rate was amongst the nasal swab (78.7%) and oral fluid
samples (83.3%), while virus was not confirmed in mummified fetuses and sera. Most of the samples
analyzed by PCR originated from farm A (80 samples), and the majority of tested were positive (60%).
Molecular typing revealed presence of H1N1 subtype in farm A that is in accordance with previous results
that confirmed H1N1 as dominating subtype that circulates in commercial farms in Serbia. Serology
examination confirmed a high overall seroprevalence of 64,6%. The serum samples from nursing pigs
accounted for the highest proportion (95.4%) among those examined, as respiratory issues linked to PRDC
typically manifest in this group. Given the endemic presence of swIAVs in the farms under analysis, there is
a pressing need to conduct further research on the circulating viruses and enhance the control measures
employed on these farms.",
publisher = "ESFLU",
journal = "ESFLU Scientific meeting, Barcelona, 25-27th April 2023",
title = "Serological and molecular investigation of influenza in commercial pig farms in Serbia"
}

Maksimović Zorić, J., Veljović, L., Glišić, D., Jezdimirović, N., Savić, B., Milovanović, B., Maletić, J., Radosavljević, V.,& Kureljušić, B.. (2023). Serological and molecular investigation of influenza in commercial pig farms in Serbia. in ESFLU Scientific meeting, Barcelona, 25-27th April 2023
ESFLU..

Maksimović Zorić J, Veljović L, Glišić D, Jezdimirović N, Savić B, Milovanović B, Maletić J, Radosavljević V, Kureljušić B. Serological and molecular investigation of influenza in commercial pig farms in Serbia. in ESFLU Scientific meeting, Barcelona, 25-27th April 2023. 2023;..

Maksimović Zorić, Jelena, Veljović, Ljubiša, Glišić, Dimitrije, Jezdimirović, Nemanja, Savić, Božidar, Milovanović, Bojan, Maletić, Jelena, Radosavljević, Vladimir, Kureljušić, Branislav, "Serological and molecular investigation of influenza in commercial pig farms in Serbia" in ESFLU Scientific meeting, Barcelona, 25-27th April 2023 (2023).

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Savić, Božidar
AU  - Milićević, Vesna
AU  - Radanović, Oliver
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Weissenbacher-Lang, Christiane
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/544
AB  - U etiopatogenezi nekroze ušne školjke kod svinja mogu biti uključeni
infektivni agensi kao i neinfektivni faktori. Griža ušiju kao oblik
kanibalizma obično predstavlja uzrok nekroze ušne školjke kod svinja, ali se
nekroza može pojaviti i bez ikakvih dokaza o postojanju griže ušiju. Iako su
istraživači ispitivali ulogu različitih uzročnika za razvoj lezija ušne
školjke, do sada nije potvrđena definitivna etiologija.
U ovom radu opisan je slučaj nekroze ušne školjke 10 uginulih svinja sa jedne
komercijalne farme svinja u Srbiji. Prema podacima ordinirajućeg veterinara
farme, lezije na ušnoj školjki su prvi put otkrivene kod svinja starosti između
45 i 50 dana kod više od 80% jedinki, u svim boksevima u odgajivalištu. Za
ispitivanje su uzete ušne školjke uginulih svinja i sprovedena su
patomorfološka, bakteriološka i molekularno-genetička ispitivanja.
Makroskopski, ustanovljene lezije su opisane kao blagi, superficijalni
dermatitis, a u težim slučajevima, bila je prisutna duboka inflamacija dermisa
sa ulceracijom i nekrozom. Histopatološkim pregledom utvrđen je erozivni i
ulcerozni dermatitis ušne školjke sa infiltracijom neutrofilnim granulocitima
i limfocitima, fibroplazija i bazofilne kolonije bakterija u krastama.
U osam uzoraka krasti i tkiva ušiju izolovani su S. aureus (MRSA soj), S. hyicus i
Streptococcus grupe C. U dva uzorka otkriven je samo S. hyicus. Svi uzorci bili su
pozitivni na T. denticola/T. putidum grupu i negativni na Mycoplasma suis. Sedam
od deset oralnih briseva bilo je pozitivno na T. denticola/T. putidum grupu. Dva
PCR proizvoda su sekvencionirana i filogenetska analiza je pokazala genetsku
sličnost sekvenci nukleotida sa T. medium/T. vincentii grupom i Treponema pedis.
Iako su bakterijski agensi uspešno utvrđeni u ispitanim uzorcima ušnih
školjki, neinfektivni faktori, uključujući dokazanu visoku vlažnost vazduha i
deficit sirovih proteina u obroku, takođe mogu biti uključeni u razvoj sindroma
nekroze ušne školjke. Istovremena detekcija treponema u uzorcima krasti i tkiva
ušiju i uzorcima brisa usne šupljine može ukazivati na prenos bakterija tokom
griže ušiju. Ovaj slučaj još jednom naglašava multifaktorijalni karakter ovog
sindroma što otežava kontrolu i prevenciju ove bolesti.
AB  - Infectious agents as well as non-infectious factors can be involved in the
etiopathogenesis of porcine ear necrosis. Furthermore, ear biting is commonly
suggested as a cause of ear necrosis in pigs, but it may also appear without any
evidence of ear biting. Although many causative agents for the development of ear
lesions have been suggested by investigators no definitive aetiology has been
identified so far.
This report describes case of ear necrosis of 10 dead pigs from one commercial pig
farm in Serbia. According to to the data obtained by the farm veterinarian, ear lesions
were first detected in pigs between 45 and 50 days of age from all pens and more than
80% of the pig population was affected. Auriculae of dead pigs were sampled and
pathomorphological, bacteriological and molecular-genetic examinations were carried
out.
The lesions ranged from mild, superficial dermatitis to severe, deep inflammation with
exudation, ulceration and necrosis. Histopathological examination revealed erosive
and ulcerative dermatitis of the pinna with neutrophilic and lymphocytic infiltration,
fibroplasia and bacterial colonies in the crusts.
In eight ear tissue scraping samples, S. aureus (MRSA strain), S. hyicus and
Streptococcus group C were isolated. In two samples only S. hyicus was detected. All
ear tissue scraping samples tested positive for the T. denticola/T. putidum group and
negative for Mycoplasma suis. Seven out of ten oral swabs were positive for the T.
denticola/T. putidum group. Two of the PCR products were sequenced, and the
phylogenetic analysis showed a genetic relationship of the treponeme nucleotide
sequences to the T. medium/T. vincentii group and Treponema pedis.
Although bacterial agents were determined successfully in ear tissue scraping
samples, non-infectious triggering factors including proven high humidity levels and
crude protein deficiencies may also have been involved in the development of ear
necrosis syndrome. The concurrent detection of Treponema in both ear tissue
scrapings and oral swab samples might indicate the transmission of the bacterium
during ear biting. The present case once again highlights the multifactorial character
of this condition that renders the control and prevention of this disease difficult.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani)
T1  - Nekroza ušne školjke kod svinja – ispitivanje moguće infektivne etiologije
T1  - Porcine ear necrosis – investigation of possible infectious etiology
EP  - 143
SP  - 142
ER  - 

@conference{
author = "Kureljušić, Branislav and Savić, Božidar and Milićević, Vesna and Radanović, Oliver and Jezdimirović, Nemanja and Milovanović, Bojan and Weissenbacher-Lang, Christiane",
year = "2023",
abstract = "U etiopatogenezi nekroze ušne školjke kod svinja mogu biti uključeni
infektivni agensi kao i neinfektivni faktori. Griža ušiju kao oblik
kanibalizma obično predstavlja uzrok nekroze ušne školjke kod svinja, ali se
nekroza može pojaviti i bez ikakvih dokaza o postojanju griže ušiju. Iako su
istraživači ispitivali ulogu različitih uzročnika za razvoj lezija ušne
školjke, do sada nije potvrđena definitivna etiologija.
U ovom radu opisan je slučaj nekroze ušne školjke 10 uginulih svinja sa jedne
komercijalne farme svinja u Srbiji. Prema podacima ordinirajućeg veterinara
farme, lezije na ušnoj školjki su prvi put otkrivene kod svinja starosti između
45 i 50 dana kod više od 80% jedinki, u svim boksevima u odgajivalištu. Za
ispitivanje su uzete ušne školjke uginulih svinja i sprovedena su
patomorfološka, bakteriološka i molekularno-genetička ispitivanja.
Makroskopski, ustanovljene lezije su opisane kao blagi, superficijalni
dermatitis, a u težim slučajevima, bila je prisutna duboka inflamacija dermisa
sa ulceracijom i nekrozom. Histopatološkim pregledom utvrđen je erozivni i
ulcerozni dermatitis ušne školjke sa infiltracijom neutrofilnim granulocitima
i limfocitima, fibroplazija i bazofilne kolonije bakterija u krastama.
U osam uzoraka krasti i tkiva ušiju izolovani su S. aureus (MRSA soj), S. hyicus i
Streptococcus grupe C. U dva uzorka otkriven je samo S. hyicus. Svi uzorci bili su
pozitivni na T. denticola/T. putidum grupu i negativni na Mycoplasma suis. Sedam
od deset oralnih briseva bilo je pozitivno na T. denticola/T. putidum grupu. Dva
PCR proizvoda su sekvencionirana i filogenetska analiza je pokazala genetsku
sličnost sekvenci nukleotida sa T. medium/T. vincentii grupom i Treponema pedis.
Iako su bakterijski agensi uspešno utvrđeni u ispitanim uzorcima ušnih
školjki, neinfektivni faktori, uključujući dokazanu visoku vlažnost vazduha i
deficit sirovih proteina u obroku, takođe mogu biti uključeni u razvoj sindroma
nekroze ušne školjke. Istovremena detekcija treponema u uzorcima krasti i tkiva
ušiju i uzorcima brisa usne šupljine može ukazivati na prenos bakterija tokom
griže ušiju. Ovaj slučaj još jednom naglašava multifaktorijalni karakter ovog
sindroma što otežava kontrolu i prevenciju ove bolesti., Infectious agents as well as non-infectious factors can be involved in the
etiopathogenesis of porcine ear necrosis. Furthermore, ear biting is commonly
suggested as a cause of ear necrosis in pigs, but it may also appear without any
evidence of ear biting. Although many causative agents for the development of ear
lesions have been suggested by investigators no definitive aetiology has been
identified so far.
This report describes case of ear necrosis of 10 dead pigs from one commercial pig
farm in Serbia. According to to the data obtained by the farm veterinarian, ear lesions
were first detected in pigs between 45 and 50 days of age from all pens and more than
80% of the pig population was affected. Auriculae of dead pigs were sampled and
pathomorphological, bacteriological and molecular-genetic examinations were carried
out.
The lesions ranged from mild, superficial dermatitis to severe, deep inflammation with
exudation, ulceration and necrosis. Histopathological examination revealed erosive
and ulcerative dermatitis of the pinna with neutrophilic and lymphocytic infiltration,
fibroplasia and bacterial colonies in the crusts.
In eight ear tissue scraping samples, S. aureus (MRSA strain), S. hyicus and
Streptococcus group C were isolated. In two samples only S. hyicus was detected. All
ear tissue scraping samples tested positive for the T. denticola/T. putidum group and
negative for Mycoplasma suis. Seven out of ten oral swabs were positive for the T.
denticola/T. putidum group. Two of the PCR products were sequenced, and the
phylogenetic analysis showed a genetic relationship of the treponeme nucleotide
sequences to the T. medium/T. vincentii group and Treponema pedis.
Although bacterial agents were determined successfully in ear tissue scraping
samples, non-infectious triggering factors including proven high humidity levels and
crude protein deficiencies may also have been involved in the development of ear
necrosis syndrome. The concurrent detection of Treponema in both ear tissue
scrapings and oral swab samples might indicate the transmission of the bacterium
during ear biting. The present case once again highlights the multifactorial character
of this condition that renders the control and prevention of this disease difficult.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani)",
title = "Nekroza ušne školjke kod svinja – ispitivanje moguće infektivne etiologije, Porcine ear necrosis – investigation of possible infectious etiology",
pages = "143-142"
}

Kureljušić, B., Savić, B., Milićević, V., Radanović, O., Jezdimirović, N., Milovanović, B.,& Weissenbacher-Lang, C.. (2023). Nekroza ušne školjke kod svinja – ispitivanje moguće infektivne etiologije. in XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani)
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 142-143.

Kureljušić B, Savić B, Milićević V, Radanović O, Jezdimirović N, Milovanović B, Weissenbacher-Lang C. Nekroza ušne školjke kod svinja – ispitivanje moguće infektivne etiologije. in XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani). 2023;:142-143..

Kureljušić, Branislav, Savić, Božidar, Milićević, Vesna, Radanović, Oliver, Jezdimirović, Nemanja, Milovanović, Bojan, Weissenbacher-Lang, Christiane, "Nekroza ušne školjke kod svinja – ispitivanje moguće infektivne etiologije" in XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani) (2023):142-143.

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Savić, Božidar
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Maksimović Zorić, Jelena
AU  - Dobrosavljević, Ivan
AU  - Prodanov Radulović, Jasna
AU  - Glišić, Dimitrije
AU  - Milićević, Vesna
AU  - Bojkovski, Jovan
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/499
AB  - Bolesti svinja koje se karakterišu pojavom vezikularnog sindroma su slinavka i šap,
vezikularna bolest svinja, vezikularni stomatitis, vezikularni egzantem svinja i Seneka bolest
svinja. Virus slinavke i šapa, virus vezikularne bolesti svinja i Senecavirus A pripadaju familiji
Picornaviridae.
Slinavka i šap je visoko kontagiozna virusna bolest različitih vrsta papkara koja se kod
svinja karakteriše apatijom, febrom, pojavom vezikula u predelu rila, usne šupljine, papaka i
mlečne žlezde. Klinička slika kod svinja uobičajeno nije teška, a u težim slučajevima može se
javiti eksungulacija. Vrata infekcije su sluznica ždrela i tonzile gde se odvija primarna replikacija
virusa, a potom sledi viremija sa sekundarnom replikacijom virusa na predilekcionim mestima.
Poznato je da inficirana svinja može da proizvede 400 miliona infektivnih doza dnevno i da tako
predstavlja značajan izvor infekcije za druge prijemčive vrste.
Infekcija Senecavirusom A se karakteriše povišenim mortalitetom kod prsadi na sisi do
sedmog dana starosti. Kod priplodnih kategorija svinja, postoji povišena telesna temperatura,
anoreksija, letargija, pojava vezikula na rilu, sluznici usne šupljine i koronarnom rubu papaka.
Pojava bolesti kod svinja koje se karakterišu vezikularnim sindromom uvek izaziva veliku
zabrinutost imajući u vidu da je klinički nemoguće razlikovati lezije koje izaziva virus slinavke i
šapa i drugi virusi. Konačnu dijagnozu je moguće jedino potvrditi u laboratoriji. Obzirom da su
svinje prijemčive za više vrsta virusa koji dovode do vezikularnog sindroma kao i činjenicu da
svinje pozitivne na slinavku i šap izlučuju veliku količinu virusa u spoljašnju sredinu putem
aerosola, blagovremeno utvrđivanje dijagnoze je od prvorazrednog značaja.
Ukoliko postoji sumnja na neku od bolesti koje se karakterišu vezikularnim sindromom
potrebno je bez odlaganja obavestiti nadležnog veterinarskog inspektora i regionalni institut koji
zajedno sa terenskom veterinarskom službom utvrđuju dalji postupak u skladu sa zakonskom
regulativom i sprovode epizootiološki nadzor i uzorkovanje materijala za laboratorijska
ispitivanja. Uzorci prvog prioriteta su pokrovni epitel vezikula, sadržaj vezikula, oralni/nazalni brisevi i uzorci krvi. Laboratorijska dijagnostika omogućava dobijanje rezultata u roku od
nekoliko časova.
PB  - Požarevac : Sitograf RM
C3  - 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
T1  - Vezikularni sindrom kod svinja – slinavka i šap ili Seneka virus?
EP  - 78
SP  - 72
ER  - 

@conference{
author = "Kureljušić, Branislav and Savić, Božidar and Jezdimirović, Nemanja and Milovanović, Bojan and Maksimović Zorić, Jelena and Dobrosavljević, Ivan and Prodanov Radulović, Jasna and Glišić, Dimitrije and Milićević, Vesna and Bojkovski, Jovan",
year = "2023",
abstract = "Bolesti svinja koje se karakterišu pojavom vezikularnog sindroma su slinavka i šap,
vezikularna bolest svinja, vezikularni stomatitis, vezikularni egzantem svinja i Seneka bolest
svinja. Virus slinavke i šapa, virus vezikularne bolesti svinja i Senecavirus A pripadaju familiji
Picornaviridae.
Slinavka i šap je visoko kontagiozna virusna bolest različitih vrsta papkara koja se kod
svinja karakteriše apatijom, febrom, pojavom vezikula u predelu rila, usne šupljine, papaka i
mlečne žlezde. Klinička slika kod svinja uobičajeno nije teška, a u težim slučajevima može se
javiti eksungulacija. Vrata infekcije su sluznica ždrela i tonzile gde se odvija primarna replikacija
virusa, a potom sledi viremija sa sekundarnom replikacijom virusa na predilekcionim mestima.
Poznato je da inficirana svinja može da proizvede 400 miliona infektivnih doza dnevno i da tako
predstavlja značajan izvor infekcije za druge prijemčive vrste.
Infekcija Senecavirusom A se karakteriše povišenim mortalitetom kod prsadi na sisi do
sedmog dana starosti. Kod priplodnih kategorija svinja, postoji povišena telesna temperatura,
anoreksija, letargija, pojava vezikula na rilu, sluznici usne šupljine i koronarnom rubu papaka.
Pojava bolesti kod svinja koje se karakterišu vezikularnim sindromom uvek izaziva veliku
zabrinutost imajući u vidu da je klinički nemoguće razlikovati lezije koje izaziva virus slinavke i
šapa i drugi virusi. Konačnu dijagnozu je moguće jedino potvrditi u laboratoriji. Obzirom da su
svinje prijemčive za više vrsta virusa koji dovode do vezikularnog sindroma kao i činjenicu da
svinje pozitivne na slinavku i šap izlučuju veliku količinu virusa u spoljašnju sredinu putem
aerosola, blagovremeno utvrđivanje dijagnoze je od prvorazrednog značaja.
Ukoliko postoji sumnja na neku od bolesti koje se karakterišu vezikularnim sindromom
potrebno je bez odlaganja obavestiti nadležnog veterinarskog inspektora i regionalni institut koji
zajedno sa terenskom veterinarskom službom utvrđuju dalji postupak u skladu sa zakonskom
regulativom i sprovode epizootiološki nadzor i uzorkovanje materijala za laboratorijska
ispitivanja. Uzorci prvog prioriteta su pokrovni epitel vezikula, sadržaj vezikula, oralni/nazalni brisevi i uzorci krvi. Laboratorijska dijagnostika omogućava dobijanje rezultata u roku od
nekoliko časova.",
publisher = "Požarevac : Sitograf RM",
journal = "20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja",
title = "Vezikularni sindrom kod svinja – slinavka i šap ili Seneka virus?",
pages = "78-72"
}

Kureljušić, B., Savić, B., Jezdimirović, N., Milovanović, B., Maksimović Zorić, J., Dobrosavljević, I., Prodanov Radulović, J., Glišić, D., Milićević, V.,& Bojkovski, J.. (2023). Vezikularni sindrom kod svinja – slinavka i šap ili Seneka virus?. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
Požarevac : Sitograf RM., 72-78.

Kureljušić B, Savić B, Jezdimirović N, Milovanović B, Maksimović Zorić J, Dobrosavljević I, Prodanov Radulović J, Glišić D, Milićević V, Bojkovski J. Vezikularni sindrom kod svinja – slinavka i šap ili Seneka virus?. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja. 2023;:72-78..

Kureljušić, Branislav, Savić, Božidar, Jezdimirović, Nemanja, Milovanović, Bojan, Maksimović Zorić, Jelena, Dobrosavljević, Ivan, Prodanov Radulović, Jasna, Glišić, Dimitrije, Milićević, Vesna, Bojkovski, Jovan, "Vezikularni sindrom kod svinja – slinavka i šap ili Seneka virus?" in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja (2023):72-78.

TY  - CONF
AU  - Savić, Božidar
AU  - Radanović, Oliver
AU  - Kureljušić, Branislav
AU  - Zdravković, Nemanja
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Maksimović Zorić, Jelena
AU  - Milićević, Vesna
AU  - Pavlović, Ivan
AU  - Stevančević, Ognjen
AU  - Dobrosavljević, Ivan
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/504
AB  - Streptokokone infekcije svinja se pojavljuju u svim zemljama sa intenzivnom svinjarskom
proizvodnjom, a izazivaju ih patogene streptokoke različitih serogrupa. Nekoliko vrsta
streptokoka je ustanovljeno kod svinja, od kojih su neki komensali, a neki patogeni. Najznačajnija
i najrasprostranjenija streptokoka svinja je Streptococcus suis (S. suis), uzročnik septikemičnog
oboljenja ili promena lokalizovanih u organima kod prasadi na sisi, prasadi stare 5 do 10 nedelja
i starijih kategorija svinja uključujući i nazimice, krmače i nerastove. Streptococcus suis je
inkapsulirana Gram-pozitivna koka, svrstana u grupu D prema Lancefield klasifikaciji. Do danas
je utvrđeno 35 kapsluarnih serotiova S. suis, koji se međusobno razlikuju po patogenosti. Većina
sojeva S. suis izolovanih od obolelih svinja pripada serotipovima 1-9, pri čemu je serotip 2
najprevalentniji i najvirulentniji serotip u većini evroazijskih zemalja. Streptokoke mogu na
različite načine da dospeju u organizam životinja. Glavna „ulazna vrata“ infekcije kod prasadi na
sisi predstavlja pupak, kratko posle poroda, ledirana gingiva ili otvorena pulpa kod korekcije zuba,
abrazije kože na ekstremitetima kod neadekvatnih podova, a naročito kada je kod krmača prisutan
MMA sindrom odnosno sindrom postpartalne disgalakcije. Takođe, i lezije kod kupiranja repa i
kastracije muške prasadi mogu predstavljati atrijum za infekciju. Kod latentno inficiranih krmača,
streptokoke naseljavaju tonzile pa se pretpostavlja da se u ovakvim slučajevima prasad mogu
inficirati preko respiratornog sistema. Ako se prasad inficiraju od latentno inficiranih krmača do
ekspresije bolesti dolazi posle imunosupresije.
Prateći zdravstveno stanje svinja u velikim aglomeracijama nam je omogućilo da na celovit način
pratimo oboljenja streptokokne etiologije koja se pojavljuju u više kliničkih i patomorfoloških
oblika. Tako, streptokokna infekcija kod prasadi na sisi i zalučene prasadi se manifestuje kao
streptokokna septikemija novorođene prasadi, streptokokna septikemija prasadi stare 2-3 nedelje,
zatim kao artritis, osteomijelitis, endokarditis, apostematozni miokarditis, meningoencefalitis,
cefalocervikalni limfadenitis, supkutani periartikularni absces, pneumonija i zapaljenje srednjeg
uva. Od oblika streptokokne infekcije kod prasadi na sisi najfrekentnije se javljaju streptokokna
septikemija i artritisi, a kod prasadi iz odgoja meningo-encefalitisi, endokarditis, pneumonija i  
zapaljenje srednjeg uva. Vrlo retko smo imali priliku da detektujemo i cefalo-cervikalni
limfadenitis i periartikularne apcese. Kod krmača, streptokoke su bile odgovorne za razvoj
mastitisa, endometritisa i pojavu abortusa. Najfrekventnije izolovani serotip S. suis u našem
istraživanju je bio serotip 2 (45%), a pored njega detektovani su i serotipovi ½ (17%), 1 (13%), 4
(7%), 7 (6%), 9 (5%), 5 (4%) i serotip 3 (3%), kao i veći broj izolata koje nismo mogli tipizirati.
Streptokokna infekcija svinja predstavlja ozbiljan i značajan zdravstveni problem u većim
aglomeracijama, a karakterišu je različiti putevi infekcije kao i polimorfizom u izražavanju.
AB  - Streptococcal infections of pigs occur in all countries with intensive pig production, and
are caused by pathogenic streptococci of different serogroups. Several species of streptococci have
been found in pigs, some of which are commensal and some are pathogenic. Streptococcus suis
(S. Suis) is one of the most important and widespread pathogens of pigs causing septicemic disease
or localized lesions in different organs in suckling piglets, 5- to 10-week-old piglets, and older
categories of pigs including gilts, sows, and boars. Streptococcus suis is an encapsulated Grampositive cocci, classified in group D according to the Lancefield classification. A total of 35 S.
suis capsular serotypes have been identified to date, which differ in pathogenicity. Most S. suis
strains isolated from diseased pigs belong to serotypes 1-9, with serotype 2 being the most
prevalent and virulent serotype in most eurasian countries. Streptococci can enter into the body in
different ways. The main portals of infection in suckling piglets are umbilical infections shortly
after birth, gum lesions or exposed dental pulp made during tooth cutting, skin injuries on the
extremities caused by abrasive floors, especially when MMA or postpartum dysgalactia syndrome
is present in sows. Castration and tail docking wounds can also be an portals for infection. In
latently infected sows, streptococci inhabit the tonsils, thus it is assumed that piglets can be
 infected through the respiratory system. In cases of infection of piglets from latently infected
sows, the disease occur in piglets after immunosuppression.
Monitoring the health status of pigs in large agglomerations allowed us, to comprehensively
survey of clinical, pathomorphological and etiological features of streptococcal diseases. Thus,
septicemia of newborn piglets, septicemia of 2-3 week old piglets, arthritis, osteomyelitis,
endocarditis, apostematous myocarditis, meningoencephalitis, cephalocervical lymphadenitis,
subcutaneous periarticular abscess, pneumonia and otitis media, were the most severe
manifestation of the disease. The septicemia and arthritis were the most common forms of the
streptococcal disease in suckling piglets, while meningo-encephalitis, endocarditis, pneumonia
and otitis media were the most common streptococcal diseases in weaned piglets. Cephalocervical lymphadenitis and periarticular abscesses were relativly sparsely detected. The most frequently isolated serotype S. suis was serotype 2 (45%), in addition, serotypes ½ (17%), 1 (13%), 4 (7%), 7 (6%), 9 (5%), 5 (4%) and 3 (3%) were also detected, as well as a larger number of isolates that we could not type. Streptococcal infection represents severe and significant health
problem in large pig agglomerations, and is characterized by different routes of infection as well
as polymorphism in expression.
PB  - Požarevac : Sitograf RM
C3  - 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
T1  - Kliničke i patomorfološke karakteristike infekcije svinja sa Streptococcus suis
T1  - Clinical and pathological characteristics of Streptococcus suis infections in pigs
EP  - 71
SP  - 56
ER  - 

@conference{
author = "Savić, Božidar and Radanović, Oliver and Kureljušić, Branislav and Zdravković, Nemanja and Jezdimirović, Nemanja and Milovanović, Bojan and Maksimović Zorić, Jelena and Milićević, Vesna and Pavlović, Ivan and Stevančević, Ognjen and Dobrosavljević, Ivan",
year = "2023",
abstract = "Streptokokone infekcije svinja se pojavljuju u svim zemljama sa intenzivnom svinjarskom
proizvodnjom, a izazivaju ih patogene streptokoke različitih serogrupa. Nekoliko vrsta
streptokoka je ustanovljeno kod svinja, od kojih su neki komensali, a neki patogeni. Najznačajnija
i najrasprostranjenija streptokoka svinja je Streptococcus suis (S. suis), uzročnik septikemičnog
oboljenja ili promena lokalizovanih u organima kod prasadi na sisi, prasadi stare 5 do 10 nedelja
i starijih kategorija svinja uključujući i nazimice, krmače i nerastove. Streptococcus suis je
inkapsulirana Gram-pozitivna koka, svrstana u grupu D prema Lancefield klasifikaciji. Do danas
je utvrđeno 35 kapsluarnih serotiova S. suis, koji se međusobno razlikuju po patogenosti. Većina
sojeva S. suis izolovanih od obolelih svinja pripada serotipovima 1-9, pri čemu je serotip 2
najprevalentniji i najvirulentniji serotip u većini evroazijskih zemalja. Streptokoke mogu na
različite načine da dospeju u organizam životinja. Glavna „ulazna vrata“ infekcije kod prasadi na
sisi predstavlja pupak, kratko posle poroda, ledirana gingiva ili otvorena pulpa kod korekcije zuba,
abrazije kože na ekstremitetima kod neadekvatnih podova, a naročito kada je kod krmača prisutan
MMA sindrom odnosno sindrom postpartalne disgalakcije. Takođe, i lezije kod kupiranja repa i
kastracije muške prasadi mogu predstavljati atrijum za infekciju. Kod latentno inficiranih krmača,
streptokoke naseljavaju tonzile pa se pretpostavlja da se u ovakvim slučajevima prasad mogu
inficirati preko respiratornog sistema. Ako se prasad inficiraju od latentno inficiranih krmača do
ekspresije bolesti dolazi posle imunosupresije.
Prateći zdravstveno stanje svinja u velikim aglomeracijama nam je omogućilo da na celovit način
pratimo oboljenja streptokokne etiologije koja se pojavljuju u više kliničkih i patomorfoloških
oblika. Tako, streptokokna infekcija kod prasadi na sisi i zalučene prasadi se manifestuje kao
streptokokna septikemija novorođene prasadi, streptokokna septikemija prasadi stare 2-3 nedelje,
zatim kao artritis, osteomijelitis, endokarditis, apostematozni miokarditis, meningoencefalitis,
cefalocervikalni limfadenitis, supkutani periartikularni absces, pneumonija i zapaljenje srednjeg
uva. Od oblika streptokokne infekcije kod prasadi na sisi najfrekentnije se javljaju streptokokna
septikemija i artritisi, a kod prasadi iz odgoja meningo-encefalitisi, endokarditis, pneumonija i  
zapaljenje srednjeg uva. Vrlo retko smo imali priliku da detektujemo i cefalo-cervikalni
limfadenitis i periartikularne apcese. Kod krmača, streptokoke su bile odgovorne za razvoj
mastitisa, endometritisa i pojavu abortusa. Najfrekventnije izolovani serotip S. suis u našem
istraživanju je bio serotip 2 (45%), a pored njega detektovani su i serotipovi ½ (17%), 1 (13%), 4
(7%), 7 (6%), 9 (5%), 5 (4%) i serotip 3 (3%), kao i veći broj izolata koje nismo mogli tipizirati.
Streptokokna infekcija svinja predstavlja ozbiljan i značajan zdravstveni problem u većim
aglomeracijama, a karakterišu je različiti putevi infekcije kao i polimorfizom u izražavanju., Streptococcal infections of pigs occur in all countries with intensive pig production, and
are caused by pathogenic streptococci of different serogroups. Several species of streptococci have
been found in pigs, some of which are commensal and some are pathogenic. Streptococcus suis
(S. Suis) is one of the most important and widespread pathogens of pigs causing septicemic disease
or localized lesions in different organs in suckling piglets, 5- to 10-week-old piglets, and older
categories of pigs including gilts, sows, and boars. Streptococcus suis is an encapsulated Grampositive cocci, classified in group D according to the Lancefield classification. A total of 35 S.
suis capsular serotypes have been identified to date, which differ in pathogenicity. Most S. suis
strains isolated from diseased pigs belong to serotypes 1-9, with serotype 2 being the most
prevalent and virulent serotype in most eurasian countries. Streptococci can enter into the body in
different ways. The main portals of infection in suckling piglets are umbilical infections shortly
after birth, gum lesions or exposed dental pulp made during tooth cutting, skin injuries on the
extremities caused by abrasive floors, especially when MMA or postpartum dysgalactia syndrome
is present in sows. Castration and tail docking wounds can also be an portals for infection. In
latently infected sows, streptococci inhabit the tonsils, thus it is assumed that piglets can be
 infected through the respiratory system. In cases of infection of piglets from latently infected
sows, the disease occur in piglets after immunosuppression.
Monitoring the health status of pigs in large agglomerations allowed us, to comprehensively
survey of clinical, pathomorphological and etiological features of streptococcal diseases. Thus,
septicemia of newborn piglets, septicemia of 2-3 week old piglets, arthritis, osteomyelitis,
endocarditis, apostematous myocarditis, meningoencephalitis, cephalocervical lymphadenitis,
subcutaneous periarticular abscess, pneumonia and otitis media, were the most severe
manifestation of the disease. The septicemia and arthritis were the most common forms of the
streptococcal disease in suckling piglets, while meningo-encephalitis, endocarditis, pneumonia
and otitis media were the most common streptococcal diseases in weaned piglets. Cephalocervical lymphadenitis and periarticular abscesses were relativly sparsely detected. The most frequently isolated serotype S. suis was serotype 2 (45%), in addition, serotypes ½ (17%), 1 (13%), 4 (7%), 7 (6%), 9 (5%), 5 (4%) and 3 (3%) were also detected, as well as a larger number of isolates that we could not type. Streptococcal infection represents severe and significant health
problem in large pig agglomerations, and is characterized by different routes of infection as well
as polymorphism in expression.",
publisher = "Požarevac : Sitograf RM",
journal = "20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja",
title = "Kliničke i patomorfološke karakteristike infekcije svinja sa Streptococcus suis, Clinical and pathological characteristics of Streptococcus suis infections in pigs",
pages = "71-56"
}

Savić, B., Radanović, O., Kureljušić, B., Zdravković, N., Jezdimirović, N., Milovanović, B., Maksimović Zorić, J., Milićević, V., Pavlović, I., Stevančević, O.,& Dobrosavljević, I.. (2023). Kliničke i patomorfološke karakteristike infekcije svinja sa Streptococcus suis. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
Požarevac : Sitograf RM., 56-71.

Savić B, Radanović O, Kureljušić B, Zdravković N, Jezdimirović N, Milovanović B, Maksimović Zorić J, Milićević V, Pavlović I, Stevančević O, Dobrosavljević I. Kliničke i patomorfološke karakteristike infekcije svinja sa Streptococcus suis. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja. 2023;:56-71..

Savić, Božidar, Radanović, Oliver, Kureljušić, Branislav, Zdravković, Nemanja, Jezdimirović, Nemanja, Milovanović, Bojan, Maksimović Zorić, Jelena, Milićević, Vesna, Pavlović, Ivan, Stevančević, Ognjen, Dobrosavljević, Ivan, "Kliničke i patomorfološke karakteristike infekcije svinja sa Streptococcus suis" in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja (2023):56-71.

TY  - CONF
AU  - Maksimović Zorić, Jelena
AU  - Veljović, Ljubiša
AU  - Glišić, Dimitrije
AU  - Savić, Božidar
AU  - Jezdimirović, Nemanja
AU  - Milovanović, Bojan
AU  - Maletić, Jelena
AU  - Spalević, Ljiljana
AU  - Kureljušić, Branislav
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/505
AB  - Influenca svinja predstavlja veoma važan zdravstvni i ekonomski problem u
komercijalnom uzgoju svinja. U etiologiji respiratornih oboljenja do kojih dovode dominiraju tri podtipa virusa influence tipa A - H1N1, H1N2 i H3N2, različitih genetskih i antigenskih karakteristika (Detmer, 2017). Iako u neimunom zapatu influenca može ostvariti visok morbiditet (i do 100%), mortalitet je uglavnom nizak (manji od 1%) i zavisi od soja virusa i prisustva drugih infekcija u zapatu (Van Reeth i sar., 2012, Zell i sar., 2013). Kao posledica cirkulacije virusa na
farmi dolazi do direktnih, i mnogo značajnijih, indirektnih gubitaka koji se ogledaju u smanjenju dnevnog prirasta, povećanju utroška hrane za kilogram prirasta, produžetku tova i dr. (Došen i sar., 2008). Na ekonomičnost proizvodnje najznačajnije utiče smanjenje dnevnog prirasta (Calderón Díaz i sar., 2020), a Haden i sar., 2012, su ustanovili da gubici po grlu u slučaju monoinfekcije virusom influence iznose 3,23$. Pored direktnih i indirektnih gubitaka u
proizvodnji, cirkulacija virusa influence u populacijama svinja predstavlja i problem od javnog značaja zbog zoonotskog potencijala koji ovi virusi poseduju i mogućih uzrokovanja oboljenja ljudi. Posle pandemije 2009. godine za koju je utvrđeno da je nastala prilagođavanjem i širenjem reasortiranog virusa svinja u humanoj populaciji (Smith i sar., 2009) opisani su mnogobrojni slučajevi oboljenja ljudi nastali prenošenjem virusa sa svinja na ljude (Hennig i sar., 2022). Iako
su to najčešće incidentni slučajevi oboljenja, a tek u nekoliko navrata oboljenje manje grupe ljudi (Hennig i sar., 2022), potencijal za prenos svinjskih virusa u humanu populaciju je evidentan, što upućuje na neophodnost praćenja raširenosti ove infekcije u zapatima svinja primenom kliničke opservacije i laboratorijskih ispitivanja obolelih.
Cirkulaciju virusa i stepen raširenosti infekcije u jednom zapatu svinja u kome se ne primenjuje vakcinacija kao mera kontrole, najlakše i najekonomičnije je utvrditi primenom laboratorijskog ispitivanja prisustva specifičnih antitela protiv virusa influence tipa A. Imunološki odgovor u vidu sinteze antitela je detektabilan već trećeg dana od nastanka infekcije (Lee i sar., 1995), pri čemu pik dostiže obično između 14. i 21. dana (Radojičić i sar., 2011). Nakon primarne infekcije nastali imunitet je dugotrajan i pruža zaštitu od infekcije istim ili drugim antigeno
sličnim sojem (Van Reeth i sar., 2012). Humoralni imunološki odgovor se ogleda u sintezi specifičnih antitela protiv hemaglutinina, neuraminidaze, nukleoproteina i matriks proteina virusa (Wright i sar., 2007), a laboratorijske metode koje se koriste za njihovu detekciju su imunoenzimski testovi (ELISA), virus neutralizacioni test (VNT) i inhibibicija hemaglutinacije (IHA) (Detmer i sar., 2013). Za testiranje velikog broja uzoraka seruma koje za cilj ima utvrđivanje seroprevalencije u jednom zapatu najpogodnije je koristiti ELISA test, dok se titar
antitela kod pojedinačnih životinja kao i podtip cirkulišućih virusa utvrđuju primenom VNT ili IHA. S' obzirom na činjenicu da je cirkulacija virusa influence tipa A potvrđena na većini velikih komercijalnih farmi u Srbiji (Maksimović Zorić i sar., 2020), izvršeno je ispitivanje seroprevalencije u različitim uzrasnim kategorijama i serotipizacija cirkulišućih virusa.
PB  - Požarevac : Sitograf RM
C3  - 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
T1  - Seroloska ispitivanja influence kod razlicitih uzrasnih kategorija svinja uzgajanih na komercijalnim farmama
EP  - 55
SP  - 48
ER  - 

@conference{
author = "Maksimović Zorić, Jelena and Veljović, Ljubiša and Glišić, Dimitrije and Savić, Božidar and Jezdimirović, Nemanja and Milovanović, Bojan and Maletić, Jelena and Spalević, Ljiljana and Kureljušić, Branislav",
year = "2023",
abstract = "Influenca svinja predstavlja veoma važan zdravstvni i ekonomski problem u
komercijalnom uzgoju svinja. U etiologiji respiratornih oboljenja do kojih dovode dominiraju tri podtipa virusa influence tipa A - H1N1, H1N2 i H3N2, različitih genetskih i antigenskih karakteristika (Detmer, 2017). Iako u neimunom zapatu influenca može ostvariti visok morbiditet (i do 100%), mortalitet je uglavnom nizak (manji od 1%) i zavisi od soja virusa i prisustva drugih infekcija u zapatu (Van Reeth i sar., 2012, Zell i sar., 2013). Kao posledica cirkulacije virusa na
farmi dolazi do direktnih, i mnogo značajnijih, indirektnih gubitaka koji se ogledaju u smanjenju dnevnog prirasta, povećanju utroška hrane za kilogram prirasta, produžetku tova i dr. (Došen i sar., 2008). Na ekonomičnost proizvodnje najznačajnije utiče smanjenje dnevnog prirasta (Calderón Díaz i sar., 2020), a Haden i sar., 2012, su ustanovili da gubici po grlu u slučaju monoinfekcije virusom influence iznose 3,23$. Pored direktnih i indirektnih gubitaka u
proizvodnji, cirkulacija virusa influence u populacijama svinja predstavlja i problem od javnog značaja zbog zoonotskog potencijala koji ovi virusi poseduju i mogućih uzrokovanja oboljenja ljudi. Posle pandemije 2009. godine za koju je utvrđeno da je nastala prilagođavanjem i širenjem reasortiranog virusa svinja u humanoj populaciji (Smith i sar., 2009) opisani su mnogobrojni slučajevi oboljenja ljudi nastali prenošenjem virusa sa svinja na ljude (Hennig i sar., 2022). Iako
su to najčešće incidentni slučajevi oboljenja, a tek u nekoliko navrata oboljenje manje grupe ljudi (Hennig i sar., 2022), potencijal za prenos svinjskih virusa u humanu populaciju je evidentan, što upućuje na neophodnost praćenja raširenosti ove infekcije u zapatima svinja primenom kliničke opservacije i laboratorijskih ispitivanja obolelih.
Cirkulaciju virusa i stepen raširenosti infekcije u jednom zapatu svinja u kome se ne primenjuje vakcinacija kao mera kontrole, najlakše i najekonomičnije je utvrditi primenom laboratorijskog ispitivanja prisustva specifičnih antitela protiv virusa influence tipa A. Imunološki odgovor u vidu sinteze antitela je detektabilan već trećeg dana od nastanka infekcije (Lee i sar., 1995), pri čemu pik dostiže obično između 14. i 21. dana (Radojičić i sar., 2011). Nakon primarne infekcije nastali imunitet je dugotrajan i pruža zaštitu od infekcije istim ili drugim antigeno
sličnim sojem (Van Reeth i sar., 2012). Humoralni imunološki odgovor se ogleda u sintezi specifičnih antitela protiv hemaglutinina, neuraminidaze, nukleoproteina i matriks proteina virusa (Wright i sar., 2007), a laboratorijske metode koje se koriste za njihovu detekciju su imunoenzimski testovi (ELISA), virus neutralizacioni test (VNT) i inhibibicija hemaglutinacije (IHA) (Detmer i sar., 2013). Za testiranje velikog broja uzoraka seruma koje za cilj ima utvrđivanje seroprevalencije u jednom zapatu najpogodnije je koristiti ELISA test, dok se titar
antitela kod pojedinačnih životinja kao i podtip cirkulišućih virusa utvrđuju primenom VNT ili IHA. S' obzirom na činjenicu da je cirkulacija virusa influence tipa A potvrđena na većini velikih komercijalnih farmi u Srbiji (Maksimović Zorić i sar., 2020), izvršeno je ispitivanje seroprevalencije u različitim uzrasnim kategorijama i serotipizacija cirkulišućih virusa.",
publisher = "Požarevac : Sitograf RM",
journal = "20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja",
title = "Seroloska ispitivanja influence kod razlicitih uzrasnih kategorija svinja uzgajanih na komercijalnim farmama",
pages = "55-48"
}

Maksimović Zorić, J., Veljović, L., Glišić, D., Savić, B., Jezdimirović, N., Milovanović, B., Maletić, J., Spalević, L.,& Kureljušić, B.. (2023). Seroloska ispitivanja influence kod razlicitih uzrasnih kategorija svinja uzgajanih na komercijalnim farmama. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja
Požarevac : Sitograf RM., 48-55.

Maksimović Zorić J, Veljović L, Glišić D, Savić B, Jezdimirović N, Milovanović B, Maletić J, Spalević L, Kureljušić B. Seroloska ispitivanja influence kod razlicitih uzrasnih kategorija svinja uzgajanih na komercijalnim farmama. in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja. 2023;:48-55..

Maksimović Zorić, Jelena, Veljović, Ljubiša, Glišić, Dimitrije, Savić, Božidar, Jezdimirović, Nemanja, Milovanović, Bojan, Maletić, Jelena, Spalević, Ljiljana, Kureljušić, Branislav, "Seroloska ispitivanja influence kod razlicitih uzrasnih kategorija svinja uzgajanih na komercijalnim farmama" in 20. Simpozijum Zdravstvena zaštita, selekcija i reprodukcija svinja (2023):48-55.

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Jezdimirović, Nemanja
AU  - Milićević, Vesna
AU  - Glišić, Dimitrije
AU  - Milovanović, Bojan
AU  - Maletić, Jelena
AU  - Maksimović Zorić, Jelena
AU  - Prodanov Radulović, Jasna
AU  - Savić, Božidar
PY  - 2023
UR  - https://swineflu.eu/wp-content/uploads/2023/06/ESFLU-Scientific-Meeting-Barcelona-2023-proceedings-3.pdf
UR  - https://reponivs.nivs.rs/handle/123456789/506
AB  - Swine influenza A is the most common respiratory disease in pig production around the world, as well as an important respiratory pathogen that affects pig health, welfare, productivity, and has zoonotic potential. Internal biosecurity practices during the pre-weaning period are critical in farms with an endemic presence of swine influenza to prevent infection and stop transmission. The current study aimed to determine whether there is a link between internal biosecurity and maintenance of influenza on the farm.
A Biocheck online survey (https://biocheckgent.com) was used to assess biosecurity at one farrow to wean pig farm in Serbia. Each assessed category was scored on a scale of 0 (worst-case scenario) to 100% (the best scenario). In the nursery, 10 udder skin wipes were obtained from lactating sows, whereas in the weaned piglets, 10 samples of oral fluid were collected and analysed for the presence of swine influenza A RNA using real-time RT-PCR. Throughout a year of monitoring, samples were collected six times every two months.
The external biosecurity assessment resulted in a score of 88%, compared to the Serbian average of 69% and the global average of 76%. External biosecurity assessments revealed the lowest scores for animal transport, carcass removal, and manure removal (71%). Internal biosecurity revealed a score of 67%, compared to the national average of 44% and the global average of 69%. Internal biosecurity was confirmed to have the lowest percentage score (36%) for the farrowing and suckling period. In this study, the overall biosecurity score for the pig farm was 78%. The national average was 57%, while the global average was 73%.
During 12 months of monitoring, swine influenza A virus positivity rate in investigated farm remained high in both set of samples. For udder skin wipes, the positivity rate ranged from 30% to 60%, and for oral fluid samples, it ranged from 50% to 80%. There was no seasonal variation in the positivity rate.
This study revealed low level of internal biosecurity for the farrowing and suckling period. The following suggestions were made to the farm manager: avoid moving pigs between litters after they are 3 days old; avoid using nurse sows; farm workers should change disposable gloves between litters; not entering in
farrowing crates and perform daily disinfection of fomites. Implementing vaccination is another preventive measure that needs to be discussed.
This study helped to identify gaps on biosecurity and risky practices in the pig farm evaluated.
PB  - ESFLU
C3  - ESFLU Scientific meeting
T1  - Low internal biosecurity: factor that favours maintenance of influenza on commercial farrow to wean pig farm in Serbia
ER  - 

@conference{
author = "Kureljušić, Branislav and Jezdimirović, Nemanja and Milićević, Vesna and Glišić, Dimitrije and Milovanović, Bojan and Maletić, Jelena and Maksimović Zorić, Jelena and Prodanov Radulović, Jasna and Savić, Božidar",
year = "2023",
abstract = "Swine influenza A is the most common respiratory disease in pig production around the world, as well as an important respiratory pathogen that affects pig health, welfare, productivity, and has zoonotic potential. Internal biosecurity practices during the pre-weaning period are critical in farms with an endemic presence of swine influenza to prevent infection and stop transmission. The current study aimed to determine whether there is a link between internal biosecurity and maintenance of influenza on the farm.
A Biocheck online survey (https://biocheckgent.com) was used to assess biosecurity at one farrow to wean pig farm in Serbia. Each assessed category was scored on a scale of 0 (worst-case scenario) to 100% (the best scenario). In the nursery, 10 udder skin wipes were obtained from lactating sows, whereas in the weaned piglets, 10 samples of oral fluid were collected and analysed for the presence of swine influenza A RNA using real-time RT-PCR. Throughout a year of monitoring, samples were collected six times every two months.
The external biosecurity assessment resulted in a score of 88%, compared to the Serbian average of 69% and the global average of 76%. External biosecurity assessments revealed the lowest scores for animal transport, carcass removal, and manure removal (71%). Internal biosecurity revealed a score of 67%, compared to the national average of 44% and the global average of 69%. Internal biosecurity was confirmed to have the lowest percentage score (36%) for the farrowing and suckling period. In this study, the overall biosecurity score for the pig farm was 78%. The national average was 57%, while the global average was 73%.
During 12 months of monitoring, swine influenza A virus positivity rate in investigated farm remained high in both set of samples. For udder skin wipes, the positivity rate ranged from 30% to 60%, and for oral fluid samples, it ranged from 50% to 80%. There was no seasonal variation in the positivity rate.
This study revealed low level of internal biosecurity for the farrowing and suckling period. The following suggestions were made to the farm manager: avoid moving pigs between litters after they are 3 days old; avoid using nurse sows; farm workers should change disposable gloves between litters; not entering in
farrowing crates and perform daily disinfection of fomites. Implementing vaccination is another preventive measure that needs to be discussed.
This study helped to identify gaps on biosecurity and risky practices in the pig farm evaluated.",
publisher = "ESFLU",
journal = "ESFLU Scientific meeting",
title = "Low internal biosecurity: factor that favours maintenance of influenza on commercial farrow to wean pig farm in Serbia"
}

Kureljušić, B., Jezdimirović, N., Milićević, V., Glišić, D., Milovanović, B., Maletić, J., Maksimović Zorić, J., Prodanov Radulović, J.,& Savić, B.. (2023). Low internal biosecurity: factor that favours maintenance of influenza on commercial farrow to wean pig farm in Serbia. in ESFLU Scientific meeting
ESFLU..

Kureljušić B, Jezdimirović N, Milićević V, Glišić D, Milovanović B, Maletić J, Maksimović Zorić J, Prodanov Radulović J, Savić B. Low internal biosecurity: factor that favours maintenance of influenza on commercial farrow to wean pig farm in Serbia. in ESFLU Scientific meeting. 2023;..

Kureljušić, Branislav, Jezdimirović, Nemanja, Milićević, Vesna, Glišić, Dimitrije, Milovanović, Bojan, Maletić, Jelena, Maksimović Zorić, Jelena, Prodanov Radulović, Jasna, Savić, Božidar, "Low internal biosecurity: factor that favours maintenance of influenza on commercial farrow to wean pig farm in Serbia" in ESFLU Scientific meeting (2023).

TY  - CONF
AU  - Kureljušić, Branislav
AU  - Maletić, Jelena
AU  - Milićević, Vesna
AU  - Savić, Božidar
AU  - Jezdimirović, Nemanja
AU  - Kureljušić, Jasna
AU  - Grubač, Siniša
AU  - Prodanov Radulović, Jasna
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/556
AB  - In Serbia, there are different animal production systems, including extensive ones, which are
common and traditional in Serbia. Nowadays, extensive pig production with very low or almost
no biosecurity measures plays an important role in the spread of ASF and other infectious
diseases. Extensive farming systems are traditionally practiced in villages, hamlets, and forests,
usually near riverbanks. In Serbia, there are different types of extensive production systems:
small farms, backyards, semi-free-range, free-range, and a small percentage of organic pig
production units. In traditional systems, pig production can also be divided into indoor and
outdoor housing. However, it is not easy to make a clear distinction between extensive indoor
and outdoor units. In traditional backyard housing systems, pigs are not confined to the units at
all times, and often there is no complete fencing. According to Serbian law, disease surveillance
is mandatory in all pig production. However, local veterinarians are mainly focused on the control
and diagnosis of transboundary infectious diseases such as ASF and CSF. For these reasons, many
other parasitic, bacterial, and sometimes viral infections are detected but underestimated.
During 2019-2023, we retrospectively analyzed the most common diseases in pigs from
traditional extensive husbandry necropsied in the Institute of Veterinary Medicine of Serbia and
the Scientific Veterinary Institute "Novi Sad". Among the most common parasitic diseases in pigs
in extensive husbandry are ascariasis and trichurosis. As for bacterial pathogens, Escherichia coli
and enteric clostridial infections, Pasteurella multocida, Glaesserella parasuis, Streptococcus spp.,
and Salmonella spp. were the most frequently isolated bacteria from various organs of the
examined pigs. The viral pathogens most commonly detected were suid herpesvirus 1 (Aujeszky's
disease) and porcine parvovirus (PPV), in addition to ASF, which was confirmed in infected
counties nationwide. Low biosecurity measures or lack of external biosecurity measures in
extensive swine production farms pose a high risk for transmission of various pathogens,
including not only diseases caused by conditionally pathogenic microorganisms, but also
notifiable diseases that can have a significant negative impact on the country's economy.
PB  - COST (European Cooperation in Science and Technology)
C3  - The 2023 Annual General Meeting of the COST action BETTER
T1  - Extensive pig production sector in Serbia – biosecurity concerns and diseases transmission
EP  - 24
SP  - 24
ER  - 

@conference{
author = "Kureljušić, Branislav and Maletić, Jelena and Milićević, Vesna and Savić, Božidar and Jezdimirović, Nemanja and Kureljušić, Jasna and Grubač, Siniša and Prodanov Radulović, Jasna",
year = "2023",
abstract = "In Serbia, there are different animal production systems, including extensive ones, which are
common and traditional in Serbia. Nowadays, extensive pig production with very low or almost
no biosecurity measures plays an important role in the spread of ASF and other infectious
diseases. Extensive farming systems are traditionally practiced in villages, hamlets, and forests,
usually near riverbanks. In Serbia, there are different types of extensive production systems:
small farms, backyards, semi-free-range, free-range, and a small percentage of organic pig
production units. In traditional systems, pig production can also be divided into indoor and
outdoor housing. However, it is not easy to make a clear distinction between extensive indoor
and outdoor units. In traditional backyard housing systems, pigs are not confined to the units at
all times, and often there is no complete fencing. According to Serbian law, disease surveillance
is mandatory in all pig production. However, local veterinarians are mainly focused on the control
and diagnosis of transboundary infectious diseases such as ASF and CSF. For these reasons, many
other parasitic, bacterial, and sometimes viral infections are detected but underestimated.
During 2019-2023, we retrospectively analyzed the most common diseases in pigs from
traditional extensive husbandry necropsied in the Institute of Veterinary Medicine of Serbia and
the Scientific Veterinary Institute "Novi Sad". Among the most common parasitic diseases in pigs
in extensive husbandry are ascariasis and trichurosis. As for bacterial pathogens, Escherichia coli
and enteric clostridial infections, Pasteurella multocida, Glaesserella parasuis, Streptococcus spp.,
and Salmonella spp. were the most frequently isolated bacteria from various organs of the
examined pigs. The viral pathogens most commonly detected were suid herpesvirus 1 (Aujeszky's
disease) and porcine parvovirus (PPV), in addition to ASF, which was confirmed in infected
counties nationwide. Low biosecurity measures or lack of external biosecurity measures in
extensive swine production farms pose a high risk for transmission of various pathogens,
including not only diseases caused by conditionally pathogenic microorganisms, but also
notifiable diseases that can have a significant negative impact on the country's economy.",
publisher = "COST (European Cooperation in Science and Technology)",
journal = "The 2023 Annual General Meeting of the COST action BETTER",
title = "Extensive pig production sector in Serbia – biosecurity concerns and diseases transmission",
pages = "24-24"
}

Kureljušić, B., Maletić, J., Milićević, V., Savić, B., Jezdimirović, N., Kureljušić, J., Grubač, S.,& Prodanov Radulović, J.. (2023). Extensive pig production sector in Serbia – biosecurity concerns and diseases transmission. in The 2023 Annual General Meeting of the COST action BETTER
COST (European Cooperation in Science and Technology)., 24-24.

Kureljušić B, Maletić J, Milićević V, Savić B, Jezdimirović N, Kureljušić J, Grubač S, Prodanov Radulović J. Extensive pig production sector in Serbia – biosecurity concerns and diseases transmission. in The 2023 Annual General Meeting of the COST action BETTER. 2023;:24-24..

Kureljušić, Branislav, Maletić, Jelena, Milićević, Vesna, Savić, Božidar, Jezdimirović, Nemanja, Kureljušić, Jasna, Grubač, Siniša, Prodanov Radulović, Jasna, "Extensive pig production sector in Serbia – biosecurity concerns and diseases transmission" in The 2023 Annual General Meeting of the COST action BETTER (2023):24-24.

TY  - CONF
AU  - Milićević, Vesna
AU  - Glišić, Dimitrije
AU  - Veljović, Ljubiša
AU  - Savić, Božidar
AU  - Kureljušić, Branislav
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/539
AB  - Virus reproduktivnog i respiratornog sindroma svinja (PRRSV) je prvi put u
Srbiji otkriven 2001. godine. PRRSV pripada familiji Arteriviridae i
razvrstava se u dva genotipa, genotip PRRSV-1 i PRRSV-2. Dok PRRSV-1
uglavnom uzrokuje respiratorne simptome, PRRSV-2 dovodi do
reproduktivnih poremećaja. Ekonomske štete koje su posledica PRRS-a su
značajne, te se danas PRRS kontroliše vakcinacijom sa više ili manje uspeha.
Pošto je virus, a naročito tip 1, izuzetno varijabilan, sa visokom stopom
mutacija i rekombinacija, potrebno je stalno praćenje sojeva, odnosno njihovo
menjanje u odnosu na dijagnostičke protokole i vakcinu. Dijagnostika PRRS-a
je upravo usled stalnih promena genoma veoma kompleksna, pa se svi sojevi
istog genotipa ne mogu detektovati jednim PCR protokolom. Genetske razlike
između PRRSV-1 i PRRSV-2 su tek značajne. Nadalje, usled primene
vakcinacije, serološka dijagnostika ima ograničenu primenu. Do 2022.
godine, u Srbiji je cirkulisao PRRS-1. U ovom radu je opisan prvi slučaj
dijagnostike i kontrole PRRSV-2 na farmi na kojoj je PRRSV-1 kontrolisan
vakcinacijom.
AB  - Porcine reproductive and respiratory syndrome virus (PRRSV) was first discovered
in Serbia in 2001. PRRSV belongs to the family Arteriviridae and is further classified
into two genotypes, genotype PRRSV-1 and PRRSV-2. While PRRSV-1 mainly
causes respiratory symptoms, PRRSV-2 leads to reproductive disorders. The
economic losses caused by PRRS are significant, and nowadays PRRS is controlled
by vaccination with more or less success. Since the virus, especially type 1, is
extremely variable, with high mutation and recombination rates, it is necessary to
constantly monitor the strains, and their changes in terms of diagnostic protocols and
vaccines. The diagnosis of PRRS is very complex precisely because of the constant
changes in the genome, so all strains of the same genotype cannot be detected by a
single PCR protocol. Genetic differences between PRRSV-1 and PRRSV-2 are even
more significant. Furthermore, due to the use of vaccination, serological diagnostics
has a limited application. Until 2022, PRRS-1 circulated in Serbia. This paper
describes the first case of diagnosis and control of PRRSV-2 on a farm where PRRSV-
1 was controlled by vaccination.
PB  - Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze
C3  - XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani)
T1  - Dijagnostika i karakteristike simultane PRRSV-1 I PRRSV-2 infekcije
T1  - Diagnosis and characteristics of simultaneous PRRSV-1 and PRRSV-2 infection
EP  - 83
SP  - 82
ER  - 

@conference{
author = "Milićević, Vesna and Glišić, Dimitrije and Veljović, Ljubiša and Savić, Božidar and Kureljušić, Branislav",
year = "2023",
abstract = "Virus reproduktivnog i respiratornog sindroma svinja (PRRSV) je prvi put u
Srbiji otkriven 2001. godine. PRRSV pripada familiji Arteriviridae i
razvrstava se u dva genotipa, genotip PRRSV-1 i PRRSV-2. Dok PRRSV-1
uglavnom uzrokuje respiratorne simptome, PRRSV-2 dovodi do
reproduktivnih poremećaja. Ekonomske štete koje su posledica PRRS-a su
značajne, te se danas PRRS kontroliše vakcinacijom sa više ili manje uspeha.
Pošto je virus, a naročito tip 1, izuzetno varijabilan, sa visokom stopom
mutacija i rekombinacija, potrebno je stalno praćenje sojeva, odnosno njihovo
menjanje u odnosu na dijagnostičke protokole i vakcinu. Dijagnostika PRRS-a
je upravo usled stalnih promena genoma veoma kompleksna, pa se svi sojevi
istog genotipa ne mogu detektovati jednim PCR protokolom. Genetske razlike
između PRRSV-1 i PRRSV-2 su tek značajne. Nadalje, usled primene
vakcinacije, serološka dijagnostika ima ograničenu primenu. Do 2022.
godine, u Srbiji je cirkulisao PRRS-1. U ovom radu je opisan prvi slučaj
dijagnostike i kontrole PRRSV-2 na farmi na kojoj je PRRSV-1 kontrolisan
vakcinacijom., Porcine reproductive and respiratory syndrome virus (PRRSV) was first discovered
in Serbia in 2001. PRRSV belongs to the family Arteriviridae and is further classified
into two genotypes, genotype PRRSV-1 and PRRSV-2. While PRRSV-1 mainly
causes respiratory symptoms, PRRSV-2 leads to reproductive disorders. The
economic losses caused by PRRS are significant, and nowadays PRRS is controlled
by vaccination with more or less success. Since the virus, especially type 1, is
extremely variable, with high mutation and recombination rates, it is necessary to
constantly monitor the strains, and their changes in terms of diagnostic protocols and
vaccines. The diagnosis of PRRS is very complex precisely because of the constant
changes in the genome, so all strains of the same genotype cannot be detected by a
single PCR protocol. Genetic differences between PRRSV-1 and PRRSV-2 are even
more significant. Furthermore, due to the use of vaccination, serological diagnostics
has a limited application. Until 2022, PRRS-1 circulated in Serbia. This paper
describes the first case of diagnosis and control of PRRSV-2 on a farm where PRRSV-
1 was controlled by vaccination.",
publisher = "Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze",
journal = "XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani)",
title = "Dijagnostika i karakteristike simultane PRRSV-1 I PRRSV-2 infekcije, Diagnosis and characteristics of simultaneous PRRSV-1 and PRRSV-2 infection",
pages = "83-82"
}

Milićević, V., Glišić, D., Veljović, L., Savić, B.,& Kureljušić, B.. (2023). Dijagnostika i karakteristike simultane PRRSV-1 I PRRSV-2 infekcije. in XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani)
Beograd : Srpsko veterinarsko društvo, Sekcija za zoonoze., 82-83.

Milićević V, Glišić D, Veljović L, Savić B, Kureljušić B. Dijagnostika i karakteristike simultane PRRSV-1 I PRRSV-2 infekcije. in XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani). 2023;:82-83..

Milićević, Vesna, Glišić, Dimitrije, Veljović, Ljubiša, Savić, Božidar, Kureljušić, Branislav, "Dijagnostika i karakteristike simultane PRRSV-1 I PRRSV-2 infekcije" in XXV Simpozijum epizootiologa i epidemiologa (XXV Epizootiološki dani) (2023):82-83.

TY  - CONF
AU  - Pavlović, Ivan
AU  - Radanović, Oliver
AU  - Zdravković, Nemanja
AU  - Savić, Božidar
AU  - Vasić, Ana
AU  - Bojkovski, Jovan
AU  - Dobrosavljević, Ivan
AU  - Stokić-Nikolić, Slavonka
AU  - Tasić, Aleksandra
AU  - Pavlović, Marija
AU  - Relić, Renata
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/500
AB  - Klasa Trematoda, u narodu poznatija kao metlji, obuhvata parazite čije telo nije
segmentisano na člančiće i poseduju organe za pričršćivanja u vidu jakih muskuloznih pijavki.
Kod svinja parazitira mali broj trematoda od kojih je većina u adultnom obliku a neke se nalaze
incistirane u larvarnom stadijumu najčešće u mišićima svinja. U Evropi je prisutan mali broj
trematoda ali su one zato u Aziji u velikom broju prisutne u patologiji svinja i ljudi. Ovde će mo
dati prikaz najznačajnih zoonotske trematoda svinja: Alaria alata, Fasciola hepatica, Dicrocelium
dendriticum, Fasciolopsis buski, Clonorchis sinensis i Opisthorchis felineus.
PB  - Požarevac : Sitograf RM
C3  - 20. Simpozijum "Zdravstvena zaštita, selekcija i reprodukcija svinja"
T1  - Trematode kod svinja
EP  - 121
SP  - 115
ER  - 

@conference{
author = "Pavlović, Ivan and Radanović, Oliver and Zdravković, Nemanja and Savić, Božidar and Vasić, Ana and Bojkovski, Jovan and Dobrosavljević, Ivan and Stokić-Nikolić, Slavonka and Tasić, Aleksandra and Pavlović, Marija and Relić, Renata",
year = "2023",
abstract = "Klasa Trematoda, u narodu poznatija kao metlji, obuhvata parazite čije telo nije
segmentisano na člančiće i poseduju organe za pričršćivanja u vidu jakih muskuloznih pijavki.
Kod svinja parazitira mali broj trematoda od kojih je većina u adultnom obliku a neke se nalaze
incistirane u larvarnom stadijumu najčešće u mišićima svinja. U Evropi je prisutan mali broj
trematoda ali su one zato u Aziji u velikom broju prisutne u patologiji svinja i ljudi. Ovde će mo
dati prikaz najznačajnih zoonotske trematoda svinja: Alaria alata, Fasciola hepatica, Dicrocelium
dendriticum, Fasciolopsis buski, Clonorchis sinensis i Opisthorchis felineus.",
publisher = "Požarevac : Sitograf RM",
journal = "20. Simpozijum "Zdravstvena zaštita, selekcija i reprodukcija svinja"",
title = "Trematode kod svinja",
pages = "121-115"
}

Pavlović, I., Radanović, O., Zdravković, N., Savić, B., Vasić, A., Bojkovski, J., Dobrosavljević, I., Stokić-Nikolić, S., Tasić, A., Pavlović, M.,& Relić, R.. (2023). Trematode kod svinja. in 20. Simpozijum "Zdravstvena zaštita, selekcija i reprodukcija svinja"
Požarevac : Sitograf RM., 115-121.

Pavlović I, Radanović O, Zdravković N, Savić B, Vasić A, Bojkovski J, Dobrosavljević I, Stokić-Nikolić S, Tasić A, Pavlović M, Relić R. Trematode kod svinja. in 20. Simpozijum "Zdravstvena zaštita, selekcija i reprodukcija svinja". 2023;:115-121..

Pavlović, Ivan, Radanović, Oliver, Zdravković, Nemanja, Savić, Božidar, Vasić, Ana, Bojkovski, Jovan, Dobrosavljević, Ivan, Stokić-Nikolić, Slavonka, Tasić, Aleksandra, Pavlović, Marija, Relić, Renata, "Trematode kod svinja" in 20. Simpozijum "Zdravstvena zaštita, selekcija i reprodukcija svinja" (2023):115-121.

TY  - CONF
AU  - Zdravković, Nemanja
AU  - Radanović, Oliver
AU  - Savić, Božidar
AU  - Ninković, Milan
AU  - Pavlović, Ivan
AU  - Bojkovski, Jovan
AU  - Jezdimirović, Nemanja
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/638
AB  - Пнеумоније у свињарској производњи представљају врло значајан здравствени и економски проблем. Поред биолошких агенаса за појаву оболења респираторног тракта, значајну улогу имају и неспецифични фактори, при чему се пре свега мисли на квалитет ваздуха, присуство микроорганизама и честица прашине у амбијенту у коме животиње бораве. Комплекс респираторне болести свиња (PRDC) је заједнички термин за пнеумоније свиња које имају мултифакторијалну етиологију, а не означава неки одрећени облик пнеумоније, при чему преваленца изолованих патогена варира између и унутар производних запата. Од прегледаних узорака плућа, најчешће изоловане бактеријске врсте биле су Pasteurella  multocida и Actinobacillus pleuropenumoniae. Значај ових узрочника пнеумонија свиња је потврђен и ранијих година.
AB  - Pneumonia in pig production represents a very significant health and economic problem. In addition to biological agents for the occurrence of respiratory tract diseases, non-specific factors also play a significant role, primarily referring to air quality,  the  presence  of  microorganisms  and  dust  particles  in  the  environment where  animals  live.  Porcine  respiratory  disease  complex  (PRDC)  is  a  collective term  for  swine  pneumonias  that  have  a  multifactorial  etiology,  rather  than  a specific  form  of  pneumonia,  with  the  prevalence  of  isolated  pathogens  varying between  and  within  production  herds.  Of  the  examined  lung  samples,  the  most frequently  isolated  bacterial  species  were  Pasteurella  multocida  and Actinobacillus  pleuropenumoniae.  The  importance  of  these  causative  agents  of swine pneumonia has been confirmed in previous years.
PB  - Banja Luka : Veterinarska komora Republike Srpske
C3  - 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina)
T1  - Bakterijske infekcije u kompleksu respiratornih bolesti svinja
T1  - Bacterial infections in the complex respiratory diseases of pigs
EP  - 34
SP  - 33
ER  - 

@conference{
author = "Zdravković, Nemanja and Radanović, Oliver and Savić, Božidar and Ninković, Milan and Pavlović, Ivan and Bojkovski, Jovan and Jezdimirović, Nemanja",
year = "2023",
abstract = "Пнеумоније у свињарској производњи представљају врло значајан здравствени и економски проблем. Поред биолошких агенаса за појаву оболења респираторног тракта, значајну улогу имају и неспецифични фактори, при чему се пре свега мисли на квалитет ваздуха, присуство микроорганизама и честица прашине у амбијенту у коме животиње бораве. Комплекс респираторне болести свиња (PRDC) је заједнички термин за пнеумоније свиња које имају мултифакторијалну етиологију, а не означава неки одрећени облик пнеумоније, при чему преваленца изолованих патогена варира између и унутар производних запата. Од прегледаних узорака плућа, најчешће изоловане бактеријске врсте биле су Pasteurella  multocida и Actinobacillus pleuropenumoniae. Значај ових узрочника пнеумонија свиња је потврђен и ранијих година., Pneumonia in pig production represents a very significant health and economic problem. In addition to biological agents for the occurrence of respiratory tract diseases, non-specific factors also play a significant role, primarily referring to air quality,  the  presence  of  microorganisms  and  dust  particles  in  the  environment where  animals  live.  Porcine  respiratory  disease  complex  (PRDC)  is  a  collective term  for  swine  pneumonias  that  have  a  multifactorial  etiology,  rather  than  a specific  form  of  pneumonia,  with  the  prevalence  of  isolated  pathogens  varying between  and  within  production  herds.  Of  the  examined  lung  samples,  the  most frequently  isolated  bacterial  species  were  Pasteurella  multocida  and Actinobacillus  pleuropenumoniae.  The  importance  of  these  causative  agents  of swine pneumonia has been confirmed in previous years.",
publisher = "Banja Luka : Veterinarska komora Republike Srpske",
journal = "28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina)",
title = "Bakterijske infekcije u kompleksu respiratornih bolesti svinja, Bacterial infections in the complex respiratory diseases of pigs",
pages = "34-33"
}

Zdravković, N., Radanović, O., Savić, B., Ninković, M., Pavlović, I., Bojkovski, J.,& Jezdimirović, N.. (2023). Bakterijske infekcije u kompleksu respiratornih bolesti svinja. in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina)
Banja Luka : Veterinarska komora Republike Srpske., 33-34.

Zdravković N, Radanović O, Savić B, Ninković M, Pavlović I, Bojkovski J, Jezdimirović N. Bakterijske infekcije u kompleksu respiratornih bolesti svinja. in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina). 2023;:33-34..

Zdravković, Nemanja, Radanović, Oliver, Savić, Božidar, Ninković, Milan, Pavlović, Ivan, Bojkovski, Jovan, Jezdimirović, Nemanja, "Bakterijske infekcije u kompleksu respiratornih bolesti svinja" in 28. Godišnje savjetovanje doktora veterinarske medicine Republike Srpske (Bosna i Hercegovina) (2023):33-34.

TY  - JOUR
AU  - Kojić, Kosta
AU  - Stevančević, Ognjen
AU  - Savić, Božidar
PY  - 2023
UR  - https://reponivs.nivs.rs/handle/123456789/632
AB  - Actinobacillus pluropneumoniae (APP) is one of the most important
bacterial respiratory pathogens in swine. It is the only etiological agent of
porcine pleuropneumoniae (PPP) or appears as a secondary bacterial infection
of the swine’s respiratory disease complex (PRDC). Antibiotics are still
the most eff ective measure for reducing mortality and severity of clinical
symptoms in most parts of the world. Nevertheless, in recent years, resistance
to certain antibiotics such as tetracycline, penicillin, aminoglycosides
and others has been increasing. Th e aim of this study was to examine the
resistance of A. pleuropneumoniae isolates in the area of AP Vojvodina. Th e
samples were collected from dead pigs’ lung tissue from 14 farms. Bacterial
strains were isolated on agar with 5% sheep blood and Staphylococcus
aureus culture as a source of factor V and for subculture chocolate agar
enriched with 10 mg/L NAD was included as well. Aft er the examination
of morphological and cultural characteristics, biochemical identifi cation
was performed using standard bacteriological tests. APP was confi rmed by
PCR. A total of 35 bacterial isolates were tested on antimicrobial resistance
using the disc diff usion method with 11 antibiotics. Antibiotics from
the group: aminoglycosides, sulfonamides, fl uoroquinolones, phenicols,
tetracyclines and beta-lactam antibiotics were used. Th e isolates collected
in the area of AP Vojvodina, from 2015 to 2022, retained high sensitivity
to fl orfenicol, cephalosporins and fl uoroquinolones. However, increasing antibiotic resistance was observed for penicillin, tetracycline and all tested
aminoglycosides.
AB  - Actinobacillus pleuropneumoniae (APP) se ubraja u najznačajnije bakterijske
respiratorne patogene svinja. Jedini je etiološki agens porcine pleuropneumoniae
(PPP) ili se pojavljuje kao sekundarna bakterijska infekcija
u kompleksu respiratorne bolesti svinja (PRDC). Antibiotici su i dalje najefi
kasnija mera za smanjenje mortaliteta i težine kliničke slike u većini dijelova
svijeta, međutim tokom prethodnih godina javlja sve češća pojava
rezistencije na pojedine antibiotske preparate poput tetraciklina, penicilina,
aminoglikozida i dr. Cilj ove studije jeste ispitati rezisteniciju izolata
A. pleuropneumoniae na prostoru AP Vojvodine. Uzorci su prikupljeni iz
plućnog tkiva uginulih svinja sa 14 farmi. Za izolaciju A. pleuropneumoniae
korišten je agar sa 5% ovčije krvi i kultura soja Staphylococcus aureus
kao izvor V faktora, a za presejavanje čokoladni agar obogaćen sa 10 mg/L
NAD. Nakon ispitivanja morfoloških i kulturelnih karakteristika izvršena
je biohemijska identifi kacija primenom standardnih bakterioloških testova.
APP je potvrđen pomoću PCR metode. U ispitivanju antibiotske osetljivosti
35 bakterijskih izolata korištena je disk difuziona metoda sa ukupno
11 antibiotika. Korišteni su antibiotici iz grupe:, aminoglikozida, sulfonamida,
fl uorohinolona, fenikola, tetraciklina i beta-laktamskih antibiotika
AB preparata. Izolati prikupljeni na teritoriji AP Vojvodine od 2015
do 2022 godine zadržali su visoku osetljivost na fl orfenikol, cefalosporine
i fl uorohinolone. Kod drugih antimikrobnih sredstava kao što su penicilin,tetraciklin i svi testirani aminoglikozidi, uočena je povećana rezistencija na
antibiotike.
PB  - Novi Sad : Scientific Veterinary Institute "Novi Sad"
T2  - Archives of Veterinary Medicine (Arhiv veterinarske medicine)
T1  - Antimicrobial resistance of actinobacillus pleuropneumoniae field isolates in Autonomous province of Vojvodina, Republic of Serbia
T1  - Antimikrobna rezistencija izolata actinobacillus pleuropneumoniae na teritoriji autonomne pokrajine Vojvodine, Republika Srbija
EP  - 96
IS  - 1
SP  - 87
VL  - 16
DO  - 10.46784/e-avm.v16i1.308
ER  - 

@article{
author = "Kojić, Kosta and Stevančević, Ognjen and Savić, Božidar",
year = "2023",
abstract = "Actinobacillus pluropneumoniae (APP) is one of the most important
bacterial respiratory pathogens in swine. It is the only etiological agent of
porcine pleuropneumoniae (PPP) or appears as a secondary bacterial infection
of the swine’s respiratory disease complex (PRDC). Antibiotics are still
the most eff ective measure for reducing mortality and severity of clinical
symptoms in most parts of the world. Nevertheless, in recent years, resistance
to certain antibiotics such as tetracycline, penicillin, aminoglycosides
and others has been increasing. Th e aim of this study was to examine the
resistance of A. pleuropneumoniae isolates in the area of AP Vojvodina. Th e
samples were collected from dead pigs’ lung tissue from 14 farms. Bacterial
strains were isolated on agar with 5% sheep blood and Staphylococcus
aureus culture as a source of factor V and for subculture chocolate agar
enriched with 10 mg/L NAD was included as well. Aft er the examination
of morphological and cultural characteristics, biochemical identifi cation
was performed using standard bacteriological tests. APP was confi rmed by
PCR. A total of 35 bacterial isolates were tested on antimicrobial resistance
using the disc diff usion method with 11 antibiotics. Antibiotics from
the group: aminoglycosides, sulfonamides, fl uoroquinolones, phenicols,
tetracyclines and beta-lactam antibiotics were used. Th e isolates collected
in the area of AP Vojvodina, from 2015 to 2022, retained high sensitivity
to fl orfenicol, cephalosporins and fl uoroquinolones. However, increasing antibiotic resistance was observed for penicillin, tetracycline and all tested
aminoglycosides., Actinobacillus pleuropneumoniae (APP) se ubraja u najznačajnije bakterijske
respiratorne patogene svinja. Jedini je etiološki agens porcine pleuropneumoniae
(PPP) ili se pojavljuje kao sekundarna bakterijska infekcija
u kompleksu respiratorne bolesti svinja (PRDC). Antibiotici su i dalje najefi
kasnija mera za smanjenje mortaliteta i težine kliničke slike u većini dijelova
svijeta, međutim tokom prethodnih godina javlja sve češća pojava
rezistencije na pojedine antibiotske preparate poput tetraciklina, penicilina,
aminoglikozida i dr. Cilj ove studije jeste ispitati rezisteniciju izolata
A. pleuropneumoniae na prostoru AP Vojvodine. Uzorci su prikupljeni iz
plućnog tkiva uginulih svinja sa 14 farmi. Za izolaciju A. pleuropneumoniae
korišten je agar sa 5% ovčije krvi i kultura soja Staphylococcus aureus
kao izvor V faktora, a za presejavanje čokoladni agar obogaćen sa 10 mg/L
NAD. Nakon ispitivanja morfoloških i kulturelnih karakteristika izvršena
je biohemijska identifi kacija primenom standardnih bakterioloških testova.
APP je potvrđen pomoću PCR metode. U ispitivanju antibiotske osetljivosti
35 bakterijskih izolata korištena je disk difuziona metoda sa ukupno
11 antibiotika. Korišteni su antibiotici iz grupe:, aminoglikozida, sulfonamida,
fl uorohinolona, fenikola, tetraciklina i beta-laktamskih antibiotika
AB preparata. Izolati prikupljeni na teritoriji AP Vojvodine od 2015
do 2022 godine zadržali su visoku osetljivost na fl orfenikol, cefalosporine
i fl uorohinolone. Kod drugih antimikrobnih sredstava kao što su penicilin,tetraciklin i svi testirani aminoglikozidi, uočena je povećana rezistencija na
antibiotike.",
publisher = "Novi Sad : Scientific Veterinary Institute "Novi Sad"",
journal = "Archives of Veterinary Medicine (Arhiv veterinarske medicine)",
title = "Antimicrobial resistance of actinobacillus pleuropneumoniae field isolates in Autonomous province of Vojvodina, Republic of Serbia, Antimikrobna rezistencija izolata actinobacillus pleuropneumoniae na teritoriji autonomne pokrajine Vojvodine, Republika Srbija",
pages = "96-87",
number = "1",
volume = "16",
doi = "10.46784/e-avm.v16i1.308"
}

Kojić, K., Stevančević, O.,& Savić, B.. (2023). Antimicrobial resistance of actinobacillus pleuropneumoniae field isolates in Autonomous province of Vojvodina, Republic of Serbia. in Archives of Veterinary Medicine (Arhiv veterinarske medicine)
Novi Sad : Scientific Veterinary Institute "Novi Sad"., 16(1), 87-96.
https://doi.org/10.46784/e-avm.v16i1.308

Kojić K, Stevančević O, Savić B. Antimicrobial resistance of actinobacillus pleuropneumoniae field isolates in Autonomous province of Vojvodina, Republic of Serbia. in Archives of Veterinary Medicine (Arhiv veterinarske medicine). 2023;16(1):87-96.
doi:10.46784/e-avm.v16i1.308 .

Kojić, Kosta, Stevančević, Ognjen, Savić, Božidar, "Antimicrobial resistance of actinobacillus pleuropneumoniae field isolates in Autonomous province of Vojvodina, Republic of Serbia" in Archives of Veterinary Medicine (Arhiv veterinarske medicine), 16, no. 1 (2023):87-96,
https://doi.org/10.46784/e-avm.v16i1.308 . .

TY  - JOUR
AU  - Kojić, Kosta
AU  - Stevančević, Ognjen
AU  - Savić, Božidar
AU  - Stojanac, Nenad
AU  - Davidov, Ivana
AU  - Spasojević, Jovana
AU  - Cincović, Marko
PY  - 2022
UR  - https://reponivs.nivs.rs/handle/123456789/645
AB  - Background: Actinobacillus pleuropneumoniae (A. pleuropneumoniae) is one of the most important bacterial respiratory
pathogens. It is the only etiological agent of porcine pleuropneumonia (PPP) or it appears as a secondary bacterial infection
in the swine respiratory disease complex (PRDC). In Serbia, apart from the identification of serotype 2, no tests have
been performed to establish the presence of other A. pleuropneumoniae serotypes in the pig population. The aim of this
study was to perform genotyping of A. pleuropneumoniae isolates originating from pig farms in Serbia by apx genes and
using multiplex polymerase chain reaction (mPCR).
Materials, Methods & Results: Isolates of A. pleuropneumoniae examined in this study were obtained from lungs with
macroscopically visible alterations characteristic of a A. pleuropneumoniae. A total of 46 isolates were examined. They
were extracted from the lung tissue samples of pig carcasses from 9 farms across different parts of Serbia. Genotyping
of isolates was performed in the previously described manner. Briefly, 5 pairs of oligonucleotide primers were used for
amplification of 4 different apx genes which encode synthesis of exotoxins (ApxI , ApxII , ApxIII i ApxIV) characteristic
for all A. pleuropneumoniae serotypes and biovars. Amplification of appropriate genome parts was performed with a reaction
chain polymerase (PCR) in multiplex (m) format using appropriate diagnostic kits to extract DNA from bacteria and
perform mPCR reaction. The results of genotyping of 46 isolates of A. pleuropneumoniae indicate the existence of a large
number of different serotypes of A. pleuropneumoniae on the studied farms or that different serotypes of this microorganism
circulate in the pig population in Serbia. In addition to the detection of dominant serotype 2, which was established on 7
farms, of which in 4 farms it was the only detected serotype, in the examined pig population the presence of serotypes 3, 5,
6, 7 and 9 was also found. Furthermore, the presence of 2 different serotypes of A. Pleuropneumoniae was also detected on
3 farms; on the first farm serotypes 2 and 3, on the second farm serotypes 2 and 6, and on the third farm serotypes 2 and 7.
Discussion: Although the research was done with a relatively small number of isolates of A. pleuropneumoniae, comparing
the obtained results with the results on the presence and prevalence of appropriate serotypes from other countries, we
concluded that there is significant diversity of this pathogen in the pig population in farms of Serbia. Detection of different
serotypes of A. pleuropneumoniae in the pig population and the presence of several different serotypes on 1 farm was
established for the very first time in Serbia. All isolates from our study can be characterized as highly virulent, considering
that the clinical symptoms, pathological findings and the results of bacteriological examination indicated A. pleuropneumoniae
to be the cause of animal death. Like in the neighbouring countries, the strongly pathogenic serotype 9 and the less
pathogenic serotype 2 are the most frequently identified causative agents of porcine pleuropneumonia in the Autonomous
Province of Vojvodina, Republic of Serbia. The necessity to establish the presence of all A. pleuropneumoniae serotypes
in the pig population, and in particular to determine the presence of different serotypes on individual farms, is crucial for
several reasons: making a definitive diagnosis; development of prophylactic strategies for medicines; implementation of
immunoprophylactic vaccination.
PB  - Porto Alegre : Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul
T2  - Acta Scientiae Veterinariae
T1  - Genotype profiles of Actinobacillus pleuropneumoniae isolated from pigs in Vojvodina, Serbia
SP  - 1877
VL  - 50
DO  - 10.22456/1679-9216.123206
ER  - 

@article{
author = "Kojić, Kosta and Stevančević, Ognjen and Savić, Božidar and Stojanac, Nenad and Davidov, Ivana and Spasojević, Jovana and Cincović, Marko",
year = "2022",
abstract = "Background: Actinobacillus pleuropneumoniae (A. pleuropneumoniae) is one of the most important bacterial respiratory
pathogens. It is the only etiological agent of porcine pleuropneumonia (PPP) or it appears as a secondary bacterial infection
in the swine respiratory disease complex (PRDC). In Serbia, apart from the identification of serotype 2, no tests have
been performed to establish the presence of other A. pleuropneumoniae serotypes in the pig population. The aim of this
study was to perform genotyping of A. pleuropneumoniae isolates originating from pig farms in Serbia by apx genes and
using multiplex polymerase chain reaction (mPCR).
Materials, Methods & Results: Isolates of A. pleuropneumoniae examined in this study were obtained from lungs with
macroscopically visible alterations characteristic of a A. pleuropneumoniae. A total of 46 isolates were examined. They
were extracted from the lung tissue samples of pig carcasses from 9 farms across different parts of Serbia. Genotyping
of isolates was performed in the previously described manner. Briefly, 5 pairs of oligonucleotide primers were used for
amplification of 4 different apx genes which encode synthesis of exotoxins (ApxI , ApxII , ApxIII i ApxIV) characteristic
for all A. pleuropneumoniae serotypes and biovars. Amplification of appropriate genome parts was performed with a reaction
chain polymerase (PCR) in multiplex (m) format using appropriate diagnostic kits to extract DNA from bacteria and
perform mPCR reaction. The results of genotyping of 46 isolates of A. pleuropneumoniae indicate the existence of a large
number of different serotypes of A. pleuropneumoniae on the studied farms or that different serotypes of this microorganism
circulate in the pig population in Serbia. In addition to the detection of dominant serotype 2, which was established on 7
farms, of which in 4 farms it was the only detected serotype, in the examined pig population the presence of serotypes 3, 5,
6, 7 and 9 was also found. Furthermore, the presence of 2 different serotypes of A. Pleuropneumoniae was also detected on
3 farms; on the first farm serotypes 2 and 3, on the second farm serotypes 2 and 6, and on the third farm serotypes 2 and 7.
Discussion: Although the research was done with a relatively small number of isolates of A. pleuropneumoniae, comparing
the obtained results with the results on the presence and prevalence of appropriate serotypes from other countries, we
concluded that there is significant diversity of this pathogen in the pig population in farms of Serbia. Detection of different
serotypes of A. pleuropneumoniae in the pig population and the presence of several different serotypes on 1 farm was
established for the very first time in Serbia. All isolates from our study can be characterized as highly virulent, considering
that the clinical symptoms, pathological findings and the results of bacteriological examination indicated A. pleuropneumoniae
to be the cause of animal death. Like in the neighbouring countries, the strongly pathogenic serotype 9 and the less
pathogenic serotype 2 are the most frequently identified causative agents of porcine pleuropneumonia in the Autonomous
Province of Vojvodina, Republic of Serbia. The necessity to establish the presence of all A. pleuropneumoniae serotypes
in the pig population, and in particular to determine the presence of different serotypes on individual farms, is crucial for
several reasons: making a definitive diagnosis; development of prophylactic strategies for medicines; implementation of
immunoprophylactic vaccination.",
publisher = "Porto Alegre : Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul",
journal = "Acta Scientiae Veterinariae",
title = "Genotype profiles of Actinobacillus pleuropneumoniae isolated from pigs in Vojvodina, Serbia",
pages = "1877",
volume = "50",
doi = "10.22456/1679-9216.123206"
}

Kojić, K., Stevančević, O., Savić, B., Stojanac, N., Davidov, I., Spasojević, J.,& Cincović, M.. (2022). Genotype profiles of Actinobacillus pleuropneumoniae isolated from pigs in Vojvodina, Serbia. in Acta Scientiae Veterinariae
Porto Alegre : Faculdade de Veterinária, Universidade Federal do Rio Grande do Sul., 50, 1877.
https://doi.org/10.22456/1679-9216.123206

Kojić K, Stevančević O, Savić B, Stojanac N, Davidov I, Spasojević J, Cincović M. Genotype profiles of Actinobacillus pleuropneumoniae isolated from pigs in Vojvodina, Serbia. in Acta Scientiae Veterinariae. 2022;50:1877.
doi:10.22456/1679-9216.123206 .

Kojić, Kosta, Stevančević, Ognjen, Savić, Božidar, Stojanac, Nenad, Davidov, Ivana, Spasojević, Jovana, Cincović, Marko, "Genotype profiles of Actinobacillus pleuropneumoniae isolated from pigs in Vojvodina, Serbia" in Acta Scientiae Veterinariae, 50 (2022):1877,
https://doi.org/10.22456/1679-9216.123206 . .