In vitro procena kapaciteta vezivanja kombinovanog adsorbenta (bentonit i ekstrakt ćelijskog zida kvasca) i aflatoksina b1
In vitro assessment of binding capacity of combined adsorbent (bentonite with yeast cell wall extracts) and aflatoxin b1
2020
Preuzimanje 🢃
Autori
Nešić, KsenijaJakšić, Sandra
Popov, N.
Živkov-Baloš, Milica
Pajić, M.
Zloh, B.
Polaček, Vladimir
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The contamination of animal feed with mycotoxins is a worldwide problem in the animal husbandry, but it also represents a serious threat for the whole food chain. The health of both animals and humans is potentially endangered. From this point of view aflatoxins are a class of mycotoxins especially well known. Therefore, new strategies to combat these natural contaminants are constantly being developed. The most applied method to protect animals against aflatoxicosis is the utilization of feed additives aimed to adsorb aflatoxins. In order to estimate adsorbing potential of feed additive “MycoStop DUPLO”, designed for the prevention and/or alleviation of adverse effects of aflatoxin B1 in animal nutrition, in vitro trial was conducted. As a result of the experiment, conducted at pH 5 during 120 minutes of incubation at 37°C, the optimal formulation of the adsorbent was revealed. This product, in low concentration and in the presence of high amounts of toxin, met the stringent European ...regulation requirements for minimum 90% aflatoxin binding efficiency (90.1% achieved with 0.02% adsorbent and 4 mg/L toxin concentration). In higher adsorbent (0.2%), and lower toxin (0.2 mg/L) conditions, adsorption was 99.6%. Such outcome indicated the validity of in vitro experimental approach which can serve as a reliable fast tool for triage of adsorbents and preselect them for in vivo tests.
Ključne reči:
mycotoxins / feed / feed additivesIzvor:
Archives of Veterinary Medicine, 2020, 13, 1, 41-52Izdavač:
- Naučni institut za veterinarstvo "Novi Sad", Novi Sad
Finansiranje / projekti:
- This paper is published as part of the project financed by the Inovation Fund of the Republic of Serbia. The authors cordially thank INBERG d.o.o., Belgrade, Serbia for providing tested adsorbents.
Institucija/grupa
Naučni institut za veterinarstvo SrbijeTY - JOUR AU - Nešić, Ksenija AU - Jakšić, Sandra AU - Popov, N. AU - Živkov-Baloš, Milica AU - Pajić, M. AU - Zloh, B. AU - Polaček, Vladimir PY - 2020 UR - https://reponivs.nivs.rs/handle/123456789/405 AB - The contamination of animal feed with mycotoxins is a worldwide problem in the animal husbandry, but it also represents a serious threat for the whole food chain. The health of both animals and humans is potentially endangered. From this point of view aflatoxins are a class of mycotoxins especially well known. Therefore, new strategies to combat these natural contaminants are constantly being developed. The most applied method to protect animals against aflatoxicosis is the utilization of feed additives aimed to adsorb aflatoxins. In order to estimate adsorbing potential of feed additive “MycoStop DUPLO”, designed for the prevention and/or alleviation of adverse effects of aflatoxin B1 in animal nutrition, in vitro trial was conducted. As a result of the experiment, conducted at pH 5 during 120 minutes of incubation at 37°C, the optimal formulation of the adsorbent was revealed. This product, in low concentration and in the presence of high amounts of toxin, met the stringent European regulation requirements for minimum 90% aflatoxin binding efficiency (90.1% achieved with 0.02% adsorbent and 4 mg/L toxin concentration). In higher adsorbent (0.2%), and lower toxin (0.2 mg/L) conditions, adsorption was 99.6%. Such outcome indicated the validity of in vitro experimental approach which can serve as a reliable fast tool for triage of adsorbents and preselect them for in vivo tests. PB - Naučni institut za veterinarstvo "Novi Sad", Novi Sad T2 - Archives of Veterinary Medicine T1 - In vitro procena kapaciteta vezivanja kombinovanog adsorbenta (bentonit i ekstrakt ćelijskog zida kvasca) i aflatoksina b1 T1 - In vitro assessment of binding capacity of combined adsorbent (bentonite with yeast cell wall extracts) and aflatoxin b1 EP - 52 IS - 1 SP - 41 VL - 13 DO - 10.46784/e-avm.v13i1.65 UR - conv_633 ER -
@article{ author = "Nešić, Ksenija and Jakšić, Sandra and Popov, N. and Živkov-Baloš, Milica and Pajić, M. and Zloh, B. and Polaček, Vladimir", year = "2020", abstract = "The contamination of animal feed with mycotoxins is a worldwide problem in the animal husbandry, but it also represents a serious threat for the whole food chain. The health of both animals and humans is potentially endangered. From this point of view aflatoxins are a class of mycotoxins especially well known. Therefore, new strategies to combat these natural contaminants are constantly being developed. The most applied method to protect animals against aflatoxicosis is the utilization of feed additives aimed to adsorb aflatoxins. In order to estimate adsorbing potential of feed additive “MycoStop DUPLO”, designed for the prevention and/or alleviation of adverse effects of aflatoxin B1 in animal nutrition, in vitro trial was conducted. As a result of the experiment, conducted at pH 5 during 120 minutes of incubation at 37°C, the optimal formulation of the adsorbent was revealed. This product, in low concentration and in the presence of high amounts of toxin, met the stringent European regulation requirements for minimum 90% aflatoxin binding efficiency (90.1% achieved with 0.02% adsorbent and 4 mg/L toxin concentration). In higher adsorbent (0.2%), and lower toxin (0.2 mg/L) conditions, adsorption was 99.6%. Such outcome indicated the validity of in vitro experimental approach which can serve as a reliable fast tool for triage of adsorbents and preselect them for in vivo tests.", publisher = "Naučni institut za veterinarstvo "Novi Sad", Novi Sad", journal = "Archives of Veterinary Medicine", title = "In vitro procena kapaciteta vezivanja kombinovanog adsorbenta (bentonit i ekstrakt ćelijskog zida kvasca) i aflatoksina b1, In vitro assessment of binding capacity of combined adsorbent (bentonite with yeast cell wall extracts) and aflatoxin b1", pages = "52-41", number = "1", volume = "13", doi = "10.46784/e-avm.v13i1.65", url = "conv_633" }
Nešić, K., Jakšić, S., Popov, N., Živkov-Baloš, M., Pajić, M., Zloh, B.,& Polaček, V.. (2020). In vitro procena kapaciteta vezivanja kombinovanog adsorbenta (bentonit i ekstrakt ćelijskog zida kvasca) i aflatoksina b1. in Archives of Veterinary Medicine Naučni institut za veterinarstvo "Novi Sad", Novi Sad., 13(1), 41-52. https://doi.org/10.46784/e-avm.v13i1.65 conv_633
Nešić K, Jakšić S, Popov N, Živkov-Baloš M, Pajić M, Zloh B, Polaček V. In vitro procena kapaciteta vezivanja kombinovanog adsorbenta (bentonit i ekstrakt ćelijskog zida kvasca) i aflatoksina b1. in Archives of Veterinary Medicine. 2020;13(1):41-52. doi:10.46784/e-avm.v13i1.65 conv_633 .
Nešić, Ksenija, Jakšić, Sandra, Popov, N., Živkov-Baloš, Milica, Pajić, M., Zloh, B., Polaček, Vladimir, "In vitro procena kapaciteta vezivanja kombinovanog adsorbenta (bentonit i ekstrakt ćelijskog zida kvasca) i aflatoksina b1" in Archives of Veterinary Medicine, 13, no. 1 (2020):41-52, https://doi.org/10.46784/e-avm.v13i1.65 ., conv_633 .